Bristol Myers Squibb

• Clinical Development Strategy: Design and execute innovative Phase 0/1 clinical trials. • Define the clinical path to proof-of-concept, including the use of theranostic pairs to accelerate patient selection. • Translational & Medical Oversight: Lead the translation of preclinical pharmacology and toxicology into First-in-Human dosing strategies. • Serve as the primary medical/scientific voice for the early-stage pipeline. • Dosimetry & PK/PD: Collaborate with medical physicists to integrate radiation dosimetry into clinical protocols, ensuring optimized therapeutic windows and individualized patient safety. • Imaging Strategy: Define the imaging strategy to provide early evidence of target engagement, biodistribution, and tumor response. • Regulatory Liaison: Act as the lead clinical expert for meetings with global health authorities (FDA/EMA). • Draft and defend clinical sections of IND/CTA filings, with a focus on justifying dose-escalation schemes and safety monitoring. • Support and lead interactions with the FDA’s Division of Medical Imaging and Radiation Medicine. • KOL Collaboration: Establish a network of academic investigators and nuclear medicine specialists to ensure strategic alignment with changes in therapeutic landscapes and collaboration on early development programs. • Portfolio strategy: Lead asset strategies for RayzeBio products in early clinical development. • Mentorship: Build and mentor the RayzeBio asset teams in clinical development. Serve as manager and cross-functional leader across the RayzeBio organization.

• Set strategic priorities for the field team (this is a third-party outsourced field organization) • Motivate and inspire the team for optimal performance • Communicate and enforce the Rules of Engagement (ROE) and Ways of Work (WOW) among all team members • Monitor team performance and recommend/implement enhancements based on learnings • Continue to infuse a high performance and learning culture among the organization • Collaborate with leadership at our third-party contracted partner organization to ensure consistency in messaging and team leadership approach • Develop and nurture key customer relationships (KOLs, Executives, treatment team members, office staff) • Mine insight from external engagement that translates to internal action • Represent the Customer Experience business function in customer interactions and industry events • Challenge the status quo and evolve the current model for maximum effectiveness and to address unmet educational needs • Assess and evaluate go-to-market PAL model for future indications • Build infrastructure and model to support future indications • Represent the PAL team in key leadership reviews • Collaborate with the Customer Experience Team, including Strategy & Operations to prepare for and execute Quarterly Business Reviews • Serve as decision-maker for resource considerations for PAL field team • Collaborate with internal partners to ensure effective training and pull through for resources • Consistently engage key internal partners (Customer Experience, Brand, Market Access) to ensure a collaborative and prioritized approach to field execution for field team against most critical business priorities

• Promotes approved indications of BMS products within a defined territory or region to meet or exceed assigned sales targets in a compliant manner. • Creates demand for BMS medicines by articulating in a balanced manner the clinical and scientific rationale for use of products in appropriate patients. • Engages with and continuously maintains/grows a high level of scientific expertise in all assigned products and therapeutic areas. • Prepares and successfully implements comprehensive territory and account plans. • Proactively uses available tools such as CE^3 to derive insights and to dynamically inform call plans. • Provides feedback on experience using these tools to leadership to enable continuous improvement. • Demonstrates scientific expertise and passion in using approved scientific resources and publications to present information to HCPs and ensures medical accuracy. • Conducts in-office presentations (e.g., lunch and learns) and discusses product-related scientific information with HCPs that is consistent with label. • Organizes external speaker programs, selecting speakers from list approved by Speakers Bureau and facilitating scheduling and logistics. • Maintains a high level of working expertise on emerging data for approved indications. • Engages real-time medical support through Medical on Call to reactively answer unsolicited questions and complex technical inquiries. • Proactively collaborates with other field teams to ensure the best Customer Experience (Cx) for HCPs. • Gathers and shares relevant insights and information internally with the appropriate stakeholders to enable BMS to better serve its customers. • Complies with all laws, regulations, and policies that govern the conduct of BMS.

• Collaborate closely with R&D, Commercial, Access, and Corporate Communications to shape pipeline and portfolio strategies, ensuring alignment of medical plans with portfolio objectives. • Serve as the key medical representative on clinical development teams and study execution teams, providing scientific and medical expertise to support cross-functional deliverables such as early development strategy, trial designs, and recruitment. • Accountable for developing the integrated medical evidence plan for early pipeline assets- including therapeutic and diagnostic agents. • Oversee medical communication strategy and pull through in publications, congress planning, advisory boards, and KOL engagement. • Provide medical leadership across the medical matrix team, including medical positioning, field medical engagement, and external education. • Engage with key external thought leaders, medical organizations, and patient advocacy groups to inform strategy and uphold scientific credibility. • Mentor and develop medical staff within a matrixed environment. • Leverage AI to drive program, portfolio, or functional performance through prioritization and scaled adoption.

• Interact with clinical investigators and thought leaders to design a clinical development plan for nominated drug candidates • Lead internal study teams, and partner with investigators and CROs to design and implement clinical studies • Work closely with GPLs to ensure development and commercial optimization of Rayze Bio assets • Contribute to writing of protocols, investigator brochures, clinical study reports, and review of other clinical trial and regulatory documents • Conduct investigator meetings and lead site qualification and initiation visits with clinical trial investigators • Execute and deploy drug development strategic plans, develop contingency plans, provide technical and strategic advice, and meet milestones and budgets • Translate findings from research and nonclinical studies into clinical development opportunities • Oversee Data Review and Independent Data Monitoring Committees • Conduct clinical trials using ethical guidelines relevant to the pharmaceutical industry, and ensure compliance with these external guidelines • Establish and maintain positive relationships with clinical trial investigators and thought leaders • As needed serve as clinical lead for regulatory interactions, including preparation of briefing documents and attendance and presentation at health authority meetings. Oversee regulatory submissions for assets in prostate cancer indications • Lead cross-functional study teams and supervise and mentor clinical scientists and medical directors in executing the programs for prostate cancers. • Recruit and build and manage team of medical directors and clinical scientists as needed based on programmatic needs • Leverages AI to drive program, portfolio, or functional performance through prioritization and scaled adoption • Willing to travel approximately 30% of the time.

• Lead the Clinical Data Management function at RayzeBio, providing strategic and operational oversight across the clinical portfolio. • Serve as the Data Management lead for a high-priority clinical development program, maintaining hands-on involvement in study execution, data review, issue resolution, and risk management. • Provide leadership for NDA/BLA submission activities, including submission readiness, data standards compliance, and regulatory inspection preparedness. • Partner cross-functionally with Clinical Operations, Biostatistics, Statistical Programming, Medical Monitoring, Safety, and Regulatory Affairs to support study execution and data quality objectives. • Oversee CROs and vendors, ensuring quality, compliance, accountability, and adherence to timelines and deliverables. • Lead ongoing cross-functional data review activities and oversee the development of key data management documentation, including Data Management Plans, edit checks, validation specifications, reconciliation plans, and data transfer agreements. • Develop and implement scalable data management processes, standards, governance, and SOPs to support operational excellence and organizational growth. • Manage competing priorities across multiple studies while proactively identifying operational risks and mitigation strategies. • Build, develop, and expand the Clinical Data Management team, and foster a collaborative and high-performing team environment. • Willing to travel approximately 10% of the time. Evening and weekend work will be involved.

• Conduct non-interventional research projects using retrospective data resources in support of RWD Analytics customer needs • Communicate project status and results effectively to all stakeholders • Engage with customer teams on protocol development, statistical analysis, interpretation and presentation of results, and strategic direction of messaging and research needs • Provide scientific leadership and guidance related to health and economic outcomes research using non-interventional methods • Execute research projects across the customer team • Mentor staff in the development of functional and behavioral skills related to job performance • Engage key RWD Analytics customers in research and market access to plan and execute value focused research projects • Assess the environment and analytical tool set to ensure current needs are met and future needs are communicated by the RWD Analytics Data Development team • Complete other duties as assigned by the Director, RWD Analytics

Title: Regional Echo Liaison - Texas Location: Dallas - TX - US Houston - TX - US Full time Job Description: Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. Key Responsibilities - Build and maintain strong, collaborative relationships with Thought Leaders and Healthcare Providers - Lead peer-to-peer scientific discussions focused on the safe and appropriate use of therapies - Gather and communicate field-based insights on disease state, clinical practice, and patient management - Translate complex clinical and scientific data into clear, actionable insights for echocardiography and sonography professionals - Serve as a trusted scientific resource within the healthcare community - Align field activities with medical strategy and evolving stakeholder needs Qualifications & Experience - Graduate of an accredited ultrasound program (echocardiography required); bachelor's degree preferred - Active cardiac ultrasound registry (RDCS or RCS required) - Minimum of 5 years of adult echocardiography experience - Experience in hypertrophic cardiomyopathy (HCM) strongly preferred - Strong knowledge of HCM and familiarity with relevant scientific literature - Proven ability to interpret and communicate complex clinical data clearly and effectively - Excellent presentation, communication, and interpersonal skills - Highly organized, detail-oriented, and self-motivated - Ability to work both independently and collaboratively - Proficiency in English (written and spoken) Additional Requirements - Home-based role with 50-70% travel, including overnight and occasional weekend travel - Ability to travel by car and/or air as needed - Ability to lift up to 45 lbs and transport educational equipment (e.g., simulator) #LI-Remote If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview: Field - United States - US: $127,890 - $154,974 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include: - Health Coverage: Medical, pharmacy, dental, and vision care. - Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). - Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. Work-life benefits include: Paid Time Off - US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) - Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. - Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. Supporting People with Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. Candidate Rights BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Data Protection We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley. R1603505 : Regional Echo Liaison - Texas

Title: Associate Director, Global Clinical Scientist (Cell Therapy) Location: Princeton United States time type Full time job requisition id R1603544 Job Description: Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. The Associate Director, Global Clinical Scientist provides scientific expertise necessary to design and deliver clinical studies and programs. Position Summary / Objective - Responsible for implementation, planning, and execution of assigned clinical trial activities. Serves as Clinical Trial Lead for one or more trials - Successfully leads, plans, and executes trial level activities for multiple trials with minimal to moderate level of supervision - Provides scientific and clinical leadership to team of supporting Clinical Scientists (matrix leadership) - Co-Leads study team meetings in partnership with GDO protocol manager; and collaborate with cross functional study team members - May support clinical development planning (collaboration with Clinical Development Lead/Clinical Trial Physician for provision and analysis of data to support future planning) Position Responsibilities - Maintain a thorough understanding of assigned protocols and protocol requirements; educate supporting team members - Plan and lead the implementation all study startup/conduct/close-out activities as applicable - Evaluate innovative trial designs (collaboration with Medical Monitor/Clinical Development Lead) - Protocol and ICF development process with minimal guidance; including writing, reviewing, adjudication/resolution of cross functional comments and ensuring high clinical quality (collaboration with Medical Writing) - Site-facing activities such as training and serving as primary contact for clinical questions - Activities related to data generation and validation, including CRF design, clinical data review/query resolution; ensure consistent, quality data review by supporting CS team - Clinical data trend identification; provide trends and escalate questions to Medical Monitor - Develop clinical narrative plan; review clinical narratives - Provision of information required by Protocol Manager for development of trial budget, CRO scope of work, etc. - Review development of site and CRA training materials and presentation at SIV and Investigator meetings and support on Study committee (e.g., DMC) activities - Drafting/review and validation of clinical study reports (CSRs) and clinical portions of Regulatory Documents (e.g., IB, DSUR, regulatory responses) - Collaborate and serve as primary liaison between external partners for scientific advice Degree Requirements - Degree in Life Sciences (MD, PhD, Pharm D, MS, RN or other scientific field preferred) Experience Requirements - 5+ years of experience in clinical science, clinical research, or equivalent - Proficient knowledge of GCP/ICH, drug development process, study design, statistics, clinical operations - Proficient knowledge and skills to support program specific data review, trend identification, data interpretation - Knowledge of the establishment and operation of data monitoring committees, dose review teams, and independent response adjudication committees Key Competency Requirements - Excellent verbal, written, communication and interpersonal skills - Must be able to effectively communicate and collaborate across functions and job levels - Ability to assimilate technical information quickly - Routinely takes initiative - Detail-oriented - Strong sense of teamwork; ability to lead team activities - Proficient in Medical Terminology and medical writing skills - Proficient knowledge of the disease area(s), KOLs, indication(s), compound(s) under study (including MOA, PK/PD, biomarker & safety profile) - Proficient critical thinking, problem solving, decision making skills - Understanding of functional and cross-functional relationships - Commitment to Quality - Adaptable / Flexible - willing and able to adjust to multiple demands and shifting priorities as well as an ability to meet day-to-day challenges with confidence and professionalism - Proficient planning/project management skills (ability to develop short to mid-range plans that are realistic and effective in meeting goals) - Proficient in Microsoft Word, Excel, PowerPoint, Electronic Data Capture (e.g., RAVE), J-Review or similar data reporting tools Travel Required Domestic and International travel may be required. If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview: Brisbane - CA - US: $211,910 - $256,789 Madison - Giralda - NJ - US: $184,270 - $223,294 Princeton - NJ - US: $184,270 - $223,294 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include: - Health Coverage: Medical, pharmacy, dental, and vision care. - Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). - Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. Work-life benefits include: Paid Time Off - US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) - Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. - Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. Supporting People with Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Lead and manage clinical development strategies, ensuring alignment with regulatory goals, while mentoring clinical trial physicians and overseeing the execution and analysis of clinical studies across multiple indications.