Title: Polysomnographic Research Technologist Location: 221 Longwood Avenue Boston (Boston Lying-In) time type Part time Job Description: Site: Mass General Brigham Incorporated Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Summary Will work very independently and under general supervision to support the technical operations of the Sleep Reading Center. Responsibilities include executing protocols involving a variety of routine and non-routine experiments at a professional level: processing, scoring, editing, analyzing, and quality checking data from a wide range of data collection systems and sources, maintaining databases of polysomnographic (PSG) data, including data collected for heart rate and rhythm (ECG), sleep stages (EEG), muscle activity (EMG), oxygen saturation, carbon dioxide, respiration, and peripheral arterial tone (PAT), as well as data collected from actigraphy to estimate movement and sleep-wake times, and from other devices used to assess sleep and physical activity. The data will be obtained from studies obtained from clinical research sites across the U.S. participating in NIH-funded multicenter studies and other research studies. The Technologist will also analyze data quality trends and identify studies that meet study-specific criteria for urgent medical referrals that require timely physician notification due to extreme physiological abnormalities. Does this position require Patient Care? Yes Essential Functions -Independently processes, scores, and generates reports for polysomnography studies, actigraphy recordings, and other device data types from studies conducted in diverse clinical sites across the U.S., applying study-specific analysis protocols. -Responsible for daily monitoring, quality checking, data entering, and editing of study data received at the Sleep Reading Center. -Responsible for assisting with data collection and analysis projects. This may include independent analysis projects under the supervision of the Chief Polysomnologist, Sr. Project Manager, or PI of the Sleep Reading Center. -Performs qualitative (sleep scoring) and quantitative (spectral) analysis of polysomnography and actigraphy recordings according to standard criteria for specific research protocols conducted in association with the Sleep Reading Center. -Provides support and helps coordinate activities to prepare grants, progress reports, manuscripts, and presentations. -Assists supervisor with clerical and administrative duties associated with conferences, courses, site visits, and other events. This may include assisting with developing activities for continuing education activities. -Participates in quality assurance activities related to scoring accuracy and reliability. -Generates reports for each study, transmits reports to appropriate institutions, clinics, and researchers, and archives studies appropriately. Qualifications Education Bachelor's Degree Related Field of Study required Can this role accept experience in lieu of a degree? Yes Licenses and Credentials--RPSGT credential Experience Previous science or patient-care backgrounds and scientific research interests. 1-2 years preferred and Experience scoring polysomnography data is required, preferably in a research setting. 1-2 years preferred Knowledge, Skills and Abilities - High level of technical knowledge, communication, and reasoning skills. - Effective interpersonal skills, able to work with others with minimal conflict. - Must possess excellent organizational skills. - Ability to pay meticulous attention to detail while maintaining a sense of priority, efficiency, and a clear view of larger project objectives. - Ability to follow directions carefully and work with minimal direct supervision once trained. - Ability to maintain positive working relationships with co-workers and to work cooperatively with others. - Ability to work effectively as a member of a research team. - Display initiative and sound judgment in crisis or unexpected situations. - Willingness to assume additional work when required during acute periods of high volume Additional Job Details (if applicable) Remote Type Hybrid Work Location 221 Longwood Avenue Scheduled Weekly Hours 0 Employee Type Per Diem Work Shift Day (United States of America) Pay Range $20.16 - $29.01/Hourly Grade 5 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: 0100 Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

• Prepare and submit regulatory documents to Institutional Review Boards (IRBs) and other applicable oversight bodies. • Maintain and organize IND Safety Reports, Investigator Brochures, and other essential regulatory documentation. • Monitor and support compliance with federal regulations, sponsor requirements, and institutional policies. • Assist with regulatory submissions and ongoing regulatory affairs activities for industry-sponsored and investigator-initiated clinical trials. • Partner with Regulatory Affairs leadership, study teams, and Principal Investigators to ensure regulatory requirements are met. • Support audit and inspection readiness by maintaining complete, accurate, and current regulatory files. • Track deadlines and manage multiple priorities while ensuring timely completion of submissions and compliance-related activities. • Other duties as assigned.

Role Description We are currently seeking a Senior Business Analyst to join our team in Montgomery, Alabama (US-AL), United States. This can be a remote position with limited travel to the client’s site. The Senior Business Analyst will work closely with the State staff and act as the trusted partner supporting the full system life cycle of assigned projects, focusing on the Medicaid Claims Processing System. Responsibilities include: - Participating in the development and formulation of process specifications to meet business requirements. - Defining and documenting requirements (business, functional, and/or technical). - Performing in-depth analyses and developing plans and approaches to design and development. - Lending guidance and expertise to testing, validation, and CMS certification. - Offering guidance and insight to training activities, overall roll-out strategies, and post-production activities. - Bridging the transition of project-to-program, lending guidance to business stakeholders. - Assisting the Project Manager in project management processes and performance metrics. - Analyzing source systems and identifying potential data gaps. - Providing project management support, including: - Scope Management - Requirements Management - Defect Management - Schedule Management - Risk and Issue Management - Communications Management - Change Management - Quality Management - User Acceptance Test Management - Participating in testing strategy, plan, and results. - Assisting in transition to operations processes. - Providing input to weekly and monthly report of activities, risks, issues, observations, findings, recommendations. - Supporting monthly project summary for reporting to CMS. Qualifications - Minimum 8 years of experience as a Senior Business Analyst with 3 years working on business process modelling and management. - 5+ years of experience in MMIS or domain knowledge of Medicare, Medicaid or with a major health care payer. - 5+ years of experience at large multi-contractor organizations, including leading centralized or matrixed teams. - 2+ years of experience with MS Visio, MS Project, and MS Office 365. - Bachelor's degree or equivalent work experience. Requirements - Experience facilitating requirements development sessions. - Ability to review deliverables and processes for quality and completeness. - Experience in test case development, execution, defect identification, and reporting. - Experience developing and reviewing implementation deliverables. - Experience with data conversions. - Experience in working on projects with multiple vendors. - Strong written and verbal communication skills. Benefits - Medical, dental, and vision insurance with an employer contribution. - Flexible spending or health savings account. - Life and AD&D insurance. - Short and long-term disability coverage. - Paid time off. - Employee assistance program. - Participation in a 401k program with company match. - Additional voluntary or legally-required benefits.

Role Description Join Us as a Senior Clinical Research Associate (Level I) – Make an Impact at the Forefront of Innovation. As part of our global team, you’ll have the opportunity to perform and coordinate all aspects of the clinical monitoring and site management process. - Conduct remote or on-site visits to assess protocol and regulatory compliance and manage required documentation. - Manage procedures and guidelines from different sponsors and/or monitoring environments (i.e., FSO, FSP, Government, etc.). - Ensure that the trial is conducted in accordance with the approved protocol, ICH-GCP guidelines, applicable regulations, and SOPs. - Ensure audit readiness and develop collaborative relationships with investigational sites. Detailed tasks and responsibilities assigned to your role are outlined in the task matrix. What You’ll Do: - Monitor investigator sites with a risk-based monitoring approach, applying root cause analysis (RCA), critical thinking, and problem-solving skills. - Ensure data accuracy through SDR, SDV, and CRF review as applicable through on-site and remote monitoring activities. - Assess investigational product through physical inventory and records review. - Document observations in reports and letters in a timely manner using approved business writing standards. - Escalate observed deficiencies and issues to clinical management expeditiously and follow all issues through to resolution. - Maintain regular contact between monitoring visits with investigative sites to confirm protocol adherence and issue resolution. - Conduct monitoring tasks in accordance with the approved monitoring plan. - Participate in the investigator payment process. - Ensure shared responsibility with other project team members on issues/findings resolution. - Investigate and follow-up on findings as applicable. - Provide trial status tracking and progress update reports to the Clinical Team Manager (CTM) as required. - Ensure study systems are updated per agreed study conventions (e.g., Clinical Trial Management System, CTMS). - Perform QC check of reports generated from CTMS system where required. - Participate in investigator meetings as necessary. - Identify potential investigators in collaboration with the client company to ensure the acceptability of qualified investigative sites. - Initiate clinical trial sites according to relevant procedures to ensure compliance with protocol and regulatory obligations. - Ensure trial close out and retrieval of trial materials. - Ensure that required essential documents are complete and in place, according to ICH-GCP and applicable regulations. - Conduct on-site file reviews as per project specifications. - Contribute to the project team by assisting in preparation of project publications/tools, and sharing ideas/suggestions with team members. - Perform additional study tasks as assigned by CTM (e.g., trip report review, newsletter creation, lead CRA team calls, etc.). - Facilitate effective communication between investigative sites, the client company, and the PPD project team through written, oral, and/or electronic contacts. - Respond to company, client, and applicable regulatory requirements/audits/inspections. - Maintain & complete administrative tasks such as expense reports and timesheets in a timely manner. - Contribute to other project work and initiatives for process improvement, as required. Qualifications - Bachelor's degree in a life science related field or a Registered Nursing certification or equivalent and relevant formal academic/vocational qualification. - Total experience: at least 3 years as a CRA. - Oncology/Cell therapy experience: at least 2 years of on-site, hands-on experience. - Location: various locations. Requirements - Effective clinical monitoring skills. - Demonstrated understanding of medical/therapeutic area knowledge and medical terminology. - Excellent understanding and demonstrated application of ICH GCPs, applicable regulations, and procedural documents. - Well-developed critical thinking skills, including but not limited to critical mindset, in-depth investigation for appropriate root cause analysis and problem solving. - Ability to manage Risk Based Monitoring concepts and processes. - Effective oral and written communication skills, with the ability to communicate effectively with medical personnel. - Ability to maintain customer focus through the utilization of good listening skills, attention to detail, and the ability to perceive customers’ underlying issues. - Effective interpersonal skills. - Strong attention to detail. - Effective organizational and time management skills. - Ability to remain flexible and adaptable in a wide range of scenarios. - Ability to work in a team or independently as required. - Good computer skills: proficient knowledge of Microsoft Office and the ability to learn appropriate software. - Good English language and grammar skills. - Good presentation skills. Working Conditions and Environment - Work is performed in an office/laboratory/clinical/and/or home office environment with exposure to electrical office equipment. - Frequent drives to site locations. - Frequent travel, generally 60-80% but more for some individuals. - May also include extended overnight stays. - Exposure to biological fluids with potential exposure to infectious organisms. - Personal protective equipment required such as protective eyewear, garments, and gloves. - Exposure to fluctuating and/or extreme temperatures on rare occasions. - Must be able to comply with specific sponsor/client/site requirements, even if not required by Thermo Fisher Scientific.