• provide outsourced digital services • deliver next-generation customer experience • represent, protect and grow client brands • leverage cloud-based infrastructure

• Lead end-to-end process improvement initiatives across CTO, partnering with stakeholders to identify high-impact improvement opportunities and establish clear success metrics aligned to business outcomes • Analyze current state processes to identify inefficiencies, bottlenecks, and improvement opportunities; conduct comprehensive process mapping and documentation to establish baseline metrics and performance indicators • Complete root cause analysis using data-driven approaches to uncover underlying issues and inform improvement strategies • Challenge existing workflows and assumptions to drive innovation and standardization, developing recommendations for process redesign and optimization aligned with organizational strategy • Design future state processes that are streamlined, scalable, and measurable, ensuring solutions address stakeholder needs and drive improvements in cost, speed, quality, and customer experience • Influence stakeholders across the organization, building consensus and driving adoption of process improvements and new ways of working • Define and track KPIs to measure the success and impact of implemented improvements, communicating outcomes and learnings to stakeholders • Mentor team members on Lean Six Sigma Black Belt methodologies and best practices, reviewing process flows and building improvement capability across the organization

Role Description The Supply Chain Operations and Logistics Specialists will play a critical role in the growth of Ionis and its transformation into a fully integrated biotechnology organization, by ensuring continued access to Ionis marketed products. This individual will be responsible for managing and assisting with the operations and logistics associated with the delivery of our U.S marketed products from our US 3PL partner to our authorized distributors. An ideal candidate will have extensive knowledge of key ERP systems, contract portals, payment portals such as COUPA, and the ability to network efficiently cross functionally. This position will report to the Executive Director, Global Commercial Trade lead and may be located at our corporate headquarters in Carlsbad California, or remote, with preference to the middle-United States region. Responsibilities - Assist with managing the movement of commercially released finished goods throughout the U.S distribution ecosystem; this would be in conjunction with our 3PL partner, contracted Specialty Pharmacies and Distributors. - Assume administrative responsibilities for the creation and maintenance of new business partners in the Ionis ERP Ecosystem (SAP S4/Hana) and the subsequent management of managing customer set ups with our 3PL partner. - Integrate into the Order to Cash (OTC) team; creating strong cross functional partnerships with internal Ionis functions within Accounting, Tax, Supply Chain, and IT. - Create strong collaboration work streams with key workstreams in Ionis’s Commercial Quality Affairs, Commercial, US Marketed Access, Patient Services/Commercial Trade and Distribution, Commercial Analytics, Finance, Accounting. - Assist as directed with the maintenance and oversight of the required US Pharmacy State License renewals and updates as required. - Collaborates closely with all Supply Chain, Demand Planning, and Global Logistics leads to ensure validated and compliant means are used to deliver and transport our finished goods to authorized distributors. - Expand relationship with U.S Commercial distribution to efficiently manage key provisions of executed Distribution and Purchase agreements; such as required notice/notice periods, Accounts Receivable reconciliation activities, Return Goods processes and other contractual obligations as required. - Be a trusted Supply Chain and Operations/Logistics specialist acting as the point person to the various field teams—providing necessary support to maximize their productivity in a compliant manner. - Assume key roles within the OTC Module as assigned (Shipping Specialist, Sales Manager, Sales Clerk, etc.) - Attend and represent Ionis as key industry and customer meetings. - Represent Supply Chain on key internal cross functional product/project teams providing oversight on key logistics capabilities. Qualifications - Preferred Bachelors’, Associate, or other relevant post-secondary degree or significant industry experience. - Bio/pharmaceutical experience of minimum of 5 years with previous experience working within a commercial ecosystem and developing strong cross functional partnerships. - Strong operational and administrative oversight with a keen eye on details such as performance against KPIs and SLAs, leveraging Ionis SAP capabilities to lead decision making, and managing the Purchase Order and Invoicing for assigned vendors. - General Knowledge of the U.S Distribution ecosystem. - Strong leadership skills and ability to partner effectively and collaborate across functions to gain alignment, hold external partners accountable, and improve business performance. - Demonstrated ability and proven history of assisting with assigned projects and initiatives to completion. - Highly organized and detail oriented, with strong project management and presentation and writing skills, proactive communications. Benefits - Ionis offers an excellent benefits package! - Highly competitive benefits. Company Description For more information about Ionis and to apply for this position; reference requisition # IONIS004036. The pay scale for this position is $21.44/hour to $30.55/hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

Role Description Are you passionate about luxury travel and providing exceptional service to high-end clients? Join our team as an Entry-Level Luxury Travel Coordinator and help clients book exclusive, luxury vacations tailored to their unique preferences. This remote role offers flexibility while allowing you to work with an award-winning team in the travel industry. - Assist clients in booking luxury vacations, including five-star resorts, exclusive destinations, and private travel experiences. - Provide detailed information about luxury accommodations, activities, and experiences that suit client preferences. - Ensure a seamless booking process from start to finish, managing all reservations and client requests. - Stay informed on luxury travel trends, exclusive destinations, and premium services to provide clients with expert advice. - Offer exceptional customer service, addressing any issues or concerns promptly. Qualifications - A passion for luxury travel and a strong desire to help clients experience premium vacations. - Strong communication and organizational skills. - Basic computer skills, with the ability to use travel booking platforms and digital tools. - Ability to work independently and manage multiple tasks efficiently. - Prior experience in customer service or travel is an advantage, but not required. Requirements - Flexible work hours with the option to work remotely. Benefits - Competitive compensation with performance-based rewards. - Exclusive travel perks and discounts on luxury vacations. - Opportunity to grow within a leading luxury travel company.