• Produce and own institutional-grade research across macro, crypto, and Binance-related themes, developing original ideas, frameworks, and new methodologies, including work that connects the macro and traditional-finance backdrop to the crypto economy. • Build rigorous models and clear visualizations from market data, public on-chain data, and other sources to support the team's research and decision-making across the business. • Act as a proactive thought leader: stay ahead of market trends, risks, and opportunities, form original views early, and help shape the conversation on the themes that matter to the market and to Binance, from the macro backdrop and market structure to tokenization, DeFi, and institutional adoption. • Work with teams across the business to track and align narratives, ensuring their market developments roll up into the team's research, and the team's research in turn feeds Binance's broader narrative and supports their goals. • Build the team's external research network and share insights across the industry, amplifying the reach and distribution of research content and strengthening its positioning.

• Monitors activities conducted by clinical investigative sites as they relate to AbbVie clinical studies to ensure successful execution of the protocol. • Ensures adherence to federal regulations and applicable local regulations, Good Clinical Practices (GCPs), ICH Guidelines, AbbVie Standard Operating Procedures (SOPs), Monitoring Plans, and to quality standards in conducting clinical research. • Conducts site qualification, initiation, interim monitoring and study closeout visits for Phase I to III studies in accordance with applicable regulations, Good Clinical Practices (GCPs), ICH Guidelines, and AbbVie Standard Operating Procedures (SOPs) and business processes. • Ensures regulatory inspection readiness at assigned clinical sites. • Ensures quality of data submitted from study sites and assures timely submission of data, including appropriate reporting and follow-up for all safety events by site personnel. • Trains study site personnel on the protocol and applicable regulatory requirements in collaboration with pertinent project team members. • Identifies, evaluates and recommends new/potential investigators/sites on an ongoing basis.

• Performs site qualification, site initiation, interim monitoring, site management and close-out visits (performed on-site or remotely) ensuring regulatory, ICH-GCP and/or Good Pharmacoepidemiology Practice (GPP) and protocol compliance • Uses judgment and experience to evaluate overall performance of site and site staff and to provide recommendations regarding site-specific actions; immediately communicates/escalates serious issues to the project team and develops action plans • Maintains a working knowledge of ICH/GCP Guidelines or other applicable guidance, relevant regulations, and company SOPs/processes • Verifies the process of obtaining informed consent has been adequately performed and documented for each subject/patient as required/appropriate • Demonstrates diligence in protecting the confidentiality of each subject/patient • Assesses factors that might affect subject/patient’s safety and clinical data integrity at an investigator/physician site such as protocol deviation/violations and pharmacovigilance issues • Assesses site processes • Conducts Source Document Review of appropriate site source documents and medical records • Verifies required clinical data entered in the case report form (CRF) is accurate and complete via review of site source documents and medical records • Applies query resolution techniques remotely and on site, and provides guidance to site staff as necessary, driving query resolution to closure within agreed timelines • Utilizes available hardware and software to support the effective conduct of the clinical study data review and capture • Verifies site compliance with electronic data capture requirements • May perform investigational product (IP) inventory, reconciliation and reviews storage and security • Verifies the IP has been dispensed and administered to subjects/patients according to the protocol • Verifies issues or risks associated with blinded or randomized information related to IP • Applies knowledge of GCP/local regulations and organizational procedures to ensure IP is appropriately (re)labelled, imported and released/returned • Routinely reviews the Investigator Site File (ISF) for accuracy, timeliness and completeness • Reconciles contents of the ISF with the Trial Master File (TMF) • Ensures the investigator/physician site is aware of the requirement of archiving essential documents in accordance with local guidelines and regulations • Documents activities via confirmation letters, follow-up letters, trip reports, communication logs, and other required project documents as per SOPs and Clinical Monitoring Plan/Site Management Plan • Supports subject/patient recruitment, retention and awareness strategies • Enters data into tracking systems as required to track all observations, ongoing status and assigned action items to resolution • Understands project scope, budgets, and timelines for own and others’ activities in the clinical team; manages site-level activities / communication to ensure project objectives, deliverables and timelines are met • Must be able to quickly adapt to changing priorities to achieve goals / targets • May act as primary liaison with project site personnel, or in collaboration with Central Monitoring Associate • Prepares for and attends Investigator Meetings and/or sponsor face to face meetings • Provides guidance at the site and project level towards audit readiness standards and supports preparation for audit and required follow-up actions • May provide training or mentorship to more junior level CRAs

• Responsible for site qualification, initiation, interim monitoring, site management, and study close-out visits • Provide mentoring and guidance to less experienced CRAs and site staff when needed • Document site visit findings via written reports • Assess, monitor, and train study site staff on protocol adherence as required • Review study subject safety information and informed consent • Conduct source document verification for compliance, patient safety, and veracity of data • Review CRFs using paper or electronic data capture systems and assist sites with data query resolution • Ensure site compliance with IP receipt, accountability and return or destruction • Conduct accompanied site visits for assessment or training of other CRAs as requested and appropriate