Natera logo
Natera

We are a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.

Senior Bioinformatics Scientist

GeneralGeneralFull TimeRemoteSeniorTeam 1,001-5,000Since 2004H1B SponsorCompany SiteLinkedIn

Location

California

Posted

2 days ago

Salary

$117.4K - $146.8K / year

Seniority

Senior

Postgraduate Degree5 yrs expEnglishAWSCloudLinuxMySQLNumpyPandasPythonScikit-Learn

Job Description

Senior Bioinformatics Scientist

Natera

• Analyze complex genomic datasets leveraging scaled in-house pipelines • Architect, build, and deploy automated analysis pipelines for diagnostic tests • Engineer novel genomic analysis tools and proactively identify optimization pathways • Participate in code reviews, technical documentation • Coordinate directly with downstream infrastructure teams to ensure R&D tools scale efficiently into production systems

Job Requirements

  • Ph.D. or Master's degree with a minimum of 5 years of professional experience in Bioinformatics, Computer Science, Engineering, Biochemistry, or a related quantitative field.
  • Deep theoretical and practical understanding of high-throughput DNA sequence data analysis, including mapping, sequence alignment, and variant calling workflows.
  • Advanced understanding of data structures, algorithm design, and computational complexity.
  • Strong Python programming skills, including fluency with the scientific computing stack (NumPy, Pandas, Scikit-learn) for data manipulation, analysis, and automation.
  • Proficiency with workflow languages — Nextflow or WDL strongly preferred.
  • Extensive experience in distributed computing and cloud environments; AWS strongly preferred.
  • Deep expertise navigating Linux environments, utilizing command-line tools, and writing efficient shell scripts.
  • Demonstrated technical autonomy and rigorous data discipline when troubleshooting high-complexity algorithmic challenges.
  • Excellent communication skills with a proven track record of explaining computational results clearly to cross-functional stakeholders.
  • Prior experience working with relational databases, particularly MySQL, is highly desirable.

Benefits

  • Comprehensive medical plans for eligible employees and their dependents
  • Dental plans for eligible employees and their dependents
  • Vision plans for eligible employees and their dependents
  • Life insurance and disability plans
  • Free testing for Natera employees and their immediate families
  • Fertility care benefits
  • Pregnancy and baby bonding leave
  • 401k benefits
  • Commuter benefits
  • Generous employee referral program

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