• Serve as a trusted analytics partner to Brand teams supporting BEQALZI and BTK CDAC launch planning, execution, and ongoing performance management. • Own customer segmentation strategy and execution, including the development, refinement, and activation of segments to support brand strategy, targeting, and customer engagement. • Lead analytics using secondary data sources to generate actionable insights on customer behavior, market dynamics, patient flow, and brand performance. • Own advanced analytics modeling for the brands, including use cases such as look-alike modeling, program or campaign effectiveness measurement, and other predictive or prescriptive analytics to inform business decisions. • Develop and deliver strategic and tactical analyses to answer key business questions related to launch readiness, brand performance, customer engagement, market evolution, and competitive dynamics. • Partner closely with Brand Teams, GCMT, Medical, GCSO, and other internal teams to integrate multiple data sources into a cohesive view of business performance and opportunity. • Design and maintain launch performance measurement frameworks, dashboards, KPIs, and business reviews to track progress against strategic objectives. • Support development of market assessments, segmentation, patient or customer journey analyses, and performance storytelling for leadership audiences. • Translate analytical findings into clear recommendations that influence strategic decisions and improve launch effectiveness. • Manage projects effectively across multiple stakeholders, ensuring timely delivery, high quality outputs, and alignment with business priorities.

• Support the Director, GVP Quality in implementing GVP Quality Assurance • Ensure Pharmacovigilance activities comply with regulatory standards • Lead audit and inspection activities • Manage quality systems and risk management • Develop and manage quality metrics • Conduct GCP/GVP training as needed

Role Description The Medical Science Liaison Lead is a professional in charge of leading, managing and monitoring a team of Medical Science Liaisons in Italy and reporting into the Country Medical Director for Italy. He/she will act as a scientific and clinical expert, supporting the medical and scientific objectives of Alnylam’s portfolio in TTR. The MSL Team Lead will be responsible to co-create a comprehensive field medical plan and supporting KOL relationships within Italy. He/she will be accountable also to communicate the science and clinical application of RNAi to Healthcare Practitioners (HCPs). In addition, MSL Team Lead is expected to build strong cross-functional relationships with colleagues in Medical Affairs, Patient Advocacy and Commercial, while maintaining full compliance with all relevant company, industry, legal, and regulatory requirements. Finally, the MSL Lead will be in charge of providing medical and scientific input into the planning and execution of Medical projects. Key Responsibilities - People Leadership Responsibilities - Build and foster an inspiring team environment with a strong culture of open communication and collaboration - Lead and drive the performance, effectiveness, and impact of the MSL team - Define and execute the MSL team strategy, including the development and implementation of territory plans and clear team objectives - Partner closely with the Country Medical Director and Medical Affairs leadership to ensure strong alignment and cross-functional collaboration - Monitor, analyze, and act on performance metrics to continuously enhance team effectiveness - Provide regular updates and insights on medical activities and projects in collaboration with the Medical Director - Lead talent development and succession planning for the MSL team - Set clear priorities, delegate responsibilities, and ensure timely delivery of team objectives - Coach, mentor, and develop team members to strengthen capabilities and drive engagement - Lead recruitment and onboarding of new MSL team members - Scientific expert in TTR - Provide accurate and fair-balanced scientific and medical information (clinical data, development, publications ...) upon request, according to the needs of experts or healthcare professionals, through individual interviews or scientific meetings. - Participate in regional events, national and international congresses as agreed with Medical Director and governance. - Management of national & regional medical projects (IIS, Research collaborations, other) - Maintain a level of expertise in the evolving scientific / therapeutic area and in competitor medicines. - Non-promotional communication with healthcare professionals, respecting the principles of separation of promotional and non-promotional activities defined by the promotional information charter. - Good Clinical Practices - Be compliant to Ethics, Compliance and internal policies Qualifications - Scientific Degree and proven basic science and/or clinical background to enable engagement of Health Care Professionals in a scientifically meaningful exchange - Previous people management experience is preferred - Experience as MSL in biotech, speciality and rare disease is preferred - Experience in clinical research, patient recruitment, and investigator-sponsored trials is a plus - Experience in medical education and KOL management - Effective communication of evidence based scientific information - Ability to work collaboratively and cross-functionally - Decision-making and accountability - Hard-working, energetic and passionate about making a meaningful difference for patients and their caregivers - Outstanding interpersonal skills, including building strong working relationships, and managing and resolving conflict - Demonstrated ability to work effectively in a highly matrixed environment; strongly team oriented - Superb communication skills; oral and written, including presentation skills in Italian & English - An unwavering commitment to upholding the highest ethical, legal, regulatory and scientific standards Requirements - Italy Pay Range: €99,500 to €134,600 gross per annum - The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. - Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills and education. - This role is eligible for an annual short-term incentive award (e.g. bonus or sales incentive), an annual long-term incentive award (e.g. equity) and competitive benefits. Company Description Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Our culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity.

Role Description The Project Director for Postsecondary Education works as a part of the leadership team in the WestEd Center for Economic Mobility. The Project Director has three primary areas of responsibility: - Implementing projects that help postsecondary education systems utilize labor market information to support the economic mobility of learners. - Leading strategy and business development. - Supervising staff and cultivating their development. The ideal candidate should have the following core qualifications: - Experience in a leadership role in open-access postsecondary education, with experience leading reform initiatives. - Strong sense of labor market trends and how the focus on return on investment is reshaping the role of education in preparing people for rewarding, well-paid work. - Deep understanding of postsecondary structures and systems, including college governance, programming, data systems, and change management. - Strong facilitation skills, including leading groups of postsecondary practitioners through planning and program redesign processes that build consensus and create a shared purpose across interest holders. - A proven track record leading large, complex, multi-year projects, with demanding timelines and teams that include people not in one’s direct line of supervision, with diverse technical, programmatic, and research components. - Mastery of operational systems necessary to manage large projects such as contracting, staffing projections, budgeting, and fiscal management. - Strong business development experience, including managing a diverse portfolio of projects while continuously engaging in proposal development leading to new projects and lines of work. - Experience with supervising a team with a focus on building strong career ladders, mentoring, performance management, and staff development. Responsibilities - Provide oversight and mentoring to team members who are leading projects within the postsecondary portfolio to ensure high quality work, support fidelity to Center for Economic Mobility priorities, and foster leadership within the team. - Lead projects within the postsecondary portfolio by providing content expertise, supporting practitioners and policy makers to engage with labor market information, facilitating meetings with practitioners, and overseeing project management. - Oversee operational aspects of projects including reporting, budget development and monitoring, financial transactions, execution of project plans, and project performance. - Contribute to projects within the postsecondary portfolio in specific roles such as facilitation, technical assistance, writing reports and toolkits, and supporting planning processes. - Present information in a concise fashion in high-stakes settings such as meeting with advisory committees, legislative staff, and the press. - Support dissemination of our work through conferences, blog posts, white papers, infographics, and other presentation venues including engagement with federal and state policy leaders. - Manage partnerships across agencies and within WestEd departments. Qualifications - At least 10 years in a postsecondary education leadership or technical assistance role. - History of managing complex projects involving large project teams, multiple stakeholders, and multiple project budgets in excess of $1 million dollars. - Able to ensure that one's own and others’ work and information are complete and accurate, especially under tight timelines. - Able to communicate complex information to diverse audiences, particularly labor market information. - Track record of building partnerships that expand the impact of individual projects. - Long-term fundraising ability, including securing large-scale contracts and grants over a period of multiple years. - Experience leading teams of people in a way that supports their growth. - Able to communicate in a collaborative manner with colleagues and partners at all levels, from frontline employees to executives and external representatives. - Strong writing and visualization skills including experience with creating materials for a diverse audience with clarity and brevity and understanding. Requirements - An abiding commitment to helping people attain living wages and more stable employment. - Ability to travel – requires 25% travel time. Benefits - 15% contribution toward retirement effective day 1 of employment and immediately 100% vested. - Pre-tax Flexible Spending Accounts and Health Savings Account option. - All health/welfare benefits are effective the first of the month following the hire date. - PTO: 19 days (increases to 21 days beginning the third year of employment), 12 paid holidays. - Life Insurance: value of 3x gross salary, max of 500k. - Opportunities for annual merit-based performance increases + annual incentives. - Professional development opportunities & mentorship program. Company Description WestEd is a community of over 1,400 researchers, practitioners, consultants, and administrative professionals committed to making a qualitative difference in the lives of youth, children, and adults. We conduct and apply research, develop evidence-based solutions, and provide consulting services across the country in both rural and urban communities to improve equitable outcomes for individuals from infancy through adulthood.