Kyverna Therapeutics logo
Kyverna Therapeutics

Taming Autoimmunity™

Senior Vice President, Manufacturing and Supply

Vice PresidentVice PresidentFull TimeRemoteSeniorTeam 51-200Since 2019H1B No SponsorCompany SiteLinkedIn

Location

United States

Posted

2 days ago

Salary

$365K - $400K / year

Seniority

Senior

Bachelor Degree15 yrs expEnglish

Job Description

Senior Vice President, Manufacturing and Supply

Kyverna Therapeutics

• Evaluate, source and manage the network of contract manufacturers, cell collection centers, and contract development organizations. • Evaluate, negotiate and implement major contracts related to manufacturing, procurement and logistics management for autologous and allogeneic CAR T therapies globally. • Build and lead the manufacturing function and supply chain function, including relationship, technical management, contract negotiation and oversight of our external manufacturing and supply organizations. • Build and lead the organization to provide and manage clinical supply, materials management, sourcing and strategic sourcing for the pipeline of cell therapies (both autologous and allogeneic) for Kyverna. • Recruit, hire, and develop employees, and assess, recommend, and implement the structure and capabilities needed to grow the function in step with Kyverna’s strategic growth. • Source and lead the evaluation of qualified organizations to provide critical services, materials, or products to Kyverna. Provide strategic input, including capital planning and capacity management, and information supporting the expansion of the Kyverna footprint globally. Assist teams in building the full business case with risks, opportunities and recommendations that support the growth of Kyverna. • Lead the Supply and Ops planning for all products at Kyverna. Aggregate demand and ensure robust and agile supply strategies to meet demand. • Participate as Member/Leader for Kyverna on JSCs with external members of the supply chain. • Develop and lead the Business Operational reviews for manufacturing and supply of all Kyverna products. Assess and communicate the performance heatmap of the components of the entire supply chain. Escalate conditions of high risk and actively intervene to mitigate risks. • Ensure network readiness for pivotal/registrational studies and launch/commercial supply activities. • Develop and manage manufacturing and supply chain operational budget(s) • Provide scientific and technical guidance and serve as SME for manufacturing processes and technology adoption. • Establish and build the process for process monitoring and performance management of products produced in multiple supply points. Set the expectations for performance of this capability and manage the team to communicate and respond to signals indicating out-of-alignment conditions. • Implement and operate the supply orchestrations systems for Kyverna to track, trace, and adjust the end-to-end patient journey, meeting scheduling requirements and optimizing patient experience. • Support CMC and product development teams through collaboration on development of product history files, master files, site master plans and validation plans. • Maintain current awareness of GMP/GTP and other regulations, guidance documents, advisory committees, industry standards and trends applicable to current and future cell therapy development operations and products. • Provide key strategic Compliance best business practices to projects and cross-functional teams, including process development, manufacturing implementation, IMPD and IND preparation, and discussions with regulators.

Job Requirements

  • Degree (Bachelor or higher) in Biochemistry, Chemical Engineering, Biotechnology or equivalent
  • 15+ years of pharmaceutical manufacturing, technology transfer or process development experience with at least 5 years’ experience in leadership roles. Prior experience with Cell Therapy Manufacturing and Supply Chain management is required.
  • Expertise with cGMP manufacturing as well as regulatory requirements for biopharmaceutical products and ATMPs
  • Demonstrated ability to manage multiple complex relationships with CMO network
  • Ability to design and build the manufacturing and supply function for Kyverna
  • Deep knowledge and experience in managing manufacturing and supply operations for clinical trial products and aseptic processes, with an emphasis on cell therapies.
  • Ability to think critically, and demonstrated troubleshooting and problem-solving skills
  • Excellent interpersonal, verbal and written communication skills
  • Ability to function efficiently and independently in a changing environment
  • Self-motivated and willing to accept temporary responsibilities outside of the initial job description
  • The ability to manage and advance multiple projects simultaneously and dynamically reprioritize as needed
  • Demonstrated success in leading high performing teams.
  • Demonstrated capacity to think creatively when addressing complex situations
  • Ability to communicate effectively with Kyverna Leadership, clinical, biomarker, biostatistical, and pre-clinical scientists, and with external business partners and Regulatory Authorities.
  • Self-starter, works effectively in teams

Benefits

  • bonus
  • benefits
  • participation in Company’s stock plan

Related Categories

Related Job Pages

More Vice President Jobs

Lisinski Law Firm logo

Vice President – IT

Lisinski Law Firm

We bring compassion back to law by protecting client rights, representing and fighting for what our clients deserve.

Vice President3 days ago
Full TimeRemoteTeam 1,001-5,000Since 2020H1B No Sponsor

• Develop and execute a multi-year IT strategy that aligns with the company’s broader business objectives • Identify and implement emerging technologies (such as AI, machine learning, or automation) to modernize legacy processes • Act as the primary technical advisor to the C-suite, translating complex technical concepts into business outcomes • Oversee the design and maintenance of scalable, reliable, and secure enterprise systems (Cloud, On-prem, and Hybrid) • Ensure high availability of all internal and external-facing systems, maintaining strict Service Level Agreements (SLAs) • Negotiate and manage contracts with third-party vendors, MSPs, and software providers • Direct the development of a comprehensive security strategy to protect company data, IP, and customer privacy • Establish and test Business Continuity (BC) and Disaster Recovery (DR) plans to minimize downtime during outages or breaches • Ensure the organization adheres to relevant legal and industry standards to ensure optimal service and cost-efficiency • Develop and manage the annual IT CAPEX and OPEX budgets, ensuring maximum Return on Investment (ROI) • Build, mentor, and lead a high-performing IT team; foster a culture of continuous learning and technical excellence • Prioritize projects and resources across the IT department to meet deadlines and ensure business consistency

United States
Lincoln Financial logo

AVP, Claims Learning & Development

Lincoln Financial

We help people confidently plan for their version of a successful financial future.

Vice President3 days ago
Full TimeRemoteTeam 10,001+Since 1905H1B No Sponsor

Role Description We are excited to bring on an AVP, Learning & Development to join our Group Protection Claims & Operations training organization in a remote environment. - Sets and executes the Learning & Development strategy, incorporating emerging trends and partnering with senior leadership to drive enterprise initiatives, change management, and continuous capability building. - Leads the design and delivery of comprehensive training programs, ensuring alignment to business priorities, organizational readiness, and measurable improvements in performance, productivity, and quality. - Establishes and drives performance outcomes, setting priorities, goals, and KPIs while monitoring results and taking action to meet or exceed business objectives. - Builds and leads a high-performing team, including talent acquisition, development, coaching, and succession planning to strengthen organizational capability. - Partners with business leaders and stakeholders to assess learning needs, provide strategic guidance, and ensure effective application of training to on-the-job performance. - Drives operational excellence and innovation, including strategic process improvements, evaluation of training effectiveness, and optimization of resources (including budget oversight) to enhance impact and efficiency. Qualifications - 4 Year/Bachelor's degree or equivalent work experience (4 years of experience in lieu of Bachelor's). - 10+ Years experience in training that directly aligns with the specific responsibilities for this position, including 3+ years of managerial, supervisory, and/or demonstrated leadership experience including influencing senior management/critical stakeholders experience. - Demonstrated strong relationship management skills with internal/external clients with proven ability to develop creative and collaborative approaches. - Ability to think critically, analyze information and to evaluate the implications of a course of action or solution. - Demonstrate strong project management leadership skills including critical ability to coordinate and balance multiple projects in a time-sensitive environment, under pressure and meeting deadlines. - Confident, comfortable communicator with strong written and verbal communication skills. Requirements - Experience leveraging automation and AI tools to support curriculum and process modernization. - Travel Requirements: Up to 30%. Benefits - Clearly defined career tracks and job levels, along with associated behaviors for each of Lincoln's core values and leadership attributes. - Leadership development and virtual training opportunities. - PTO/parental leave. - Competitive 401K and employee benefits. - Free financial counseling, health coaching and employee assistance program. - Tuition assistance program. - Work arrangements that work for you. - Effective productivity/technology tools and training.

United States
$127.5K - $232.3K / year
Western Governors University logo

Lead, Student Communities

Western Governors University

WGU is driven by a mission to expand access to higher education through online, competency-based degree programs. The university is committed to being a great place to work for a diverse workforce of student-focused professionals.

Vice President3 days ago
Full TimeRemoteTeam 51-200

Role Description Develops and maintains dynamic student community programs that create a safe space for prospective students, current students, and alumni that encourages relationship building and networking for their professional success. Responsible for organizing faculty volunteers and club advisors to form a student community team as they connect with prospective, active, and former WGU students. Coordinates with volunteers and club advisors who provide input. Responsible for managing community-building initiatives which impact student success and improve the student experience. - Lead the vision, strategy, and execution of student community programs, clubs, and engagement initiatives. - Build and support a network of faculty volunteers and club advisors to strengthen student connections across the lifecycle. - Partner cross-functionally with communications, PR, enrollment, academic teams, and other stakeholders to enhance community participation. - Develop and maintain processes, policies, and programs that improve student experience and operational efficiency. - Monitor and moderate online community spaces, ensuring an inclusive, engaging, and high-quality environment. - Analyze engagement and student success metrics, including retention and graduation trends, and report insights to leadership. - Plan and execute virtual and in-person community events that increase engagement and brand awareness. Qualifications - Bachelor’s degree in Marketing, Communications, Information Technology or a related discipline. - Two (2) years of experience leading a student community with user engagement, project management, and multiple social platforms. - Experience reporting and managing data using reporting platforms such as Salesforce, Tableau or Power BI. - Strong interpersonal, communication, and conflict resolution skills with excellent writing ability. - Ability to manage multiple priorities and projects in a fast-paced environment with a results-driven mindset. - Experience building or supporting student or community engagement programs such as forums, ambassador programs, or clubs. Requirements - Master’s degree in a related field (Bonus Points). - Experience leading initiatives that promote engagement, retention, and success among underserved student populations, including first-generation, community college, and TRIO students (Bonus Points). - Experience supporting students in an online learning environment (Bonus Points). - Experience with UX design (Bonus Points). - Project management experience and ability to lead cross-functional initiatives (Bonus Points). Benefits - Eligible for bonuses. - Medical, dental, vision, telehealth and mental healthcare. - Health savings account and flexible spending account. - Basic and voluntary life insurance. - Disability coverage. - Accident, critical illness and hospital indemnity supplemental coverages. - Legal and identity theft coverage. - Retirement savings plan. - Wellbeing program. - Discounted WGU tuition. - Flexible paid time off for rest and relaxation with no need for accrual. - Flexible paid sick time with no need for accrual. - 11 paid holidays. - Other paid leaves, including up to 12 weeks of parental leave.

United States
$66.3K - $99.5K / year
Vice President3 days ago
Full TimeRemoteTeam 501-1,000Since 2007H1B No Sponsor

• Own the day-to-day execution of Skyward's cost-containment program across the stop-loss portfolio • Develop and refine cost-containment protocols, standard operating procedures (SOPs), and playbooks • Monitor and evaluate cost-containment vendor performance • Assist the VP with vendor selection, due diligence, and contract evaluation • Track, quantify, and report cost-containment savings • Stay current on emerging cost drivers, treatment modalities, regulatory changes, and market trends • Provide senior-level clinical expertise on complex, high-cost, and sensitive claims • Build and maintain executive-level relationships with TPAs, producers, policyholders, and cost-containment vendors • Serve as a senior mentor and resource to Clinical Consultants • Identify opportunities to leverage data and analytics to improve cost-containment outcomes • Design and maintain SOPs, workflows, and documentation standards

United States
$110K - $160K / year