Title: Sr Clinical Research Coordinator Sleep Medicine RL Location: Boston, MA, USA Job Description: Full time job requisition id RQ4064705 Site: The Brigham and Women's Hospital, Inc Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Summary Working independently and following established policies, procedures, and study protocols, provides assistance on clinical research studies, including recruiting, evaluating, and consenting patients for studies; collecting and organizing patient data; scheduling patients for study visits; performing clinical tests such as EKGs and anthropometry; maintaining and updating data generated by the study. Additionally, provide input into determining study subject suitability and input into recruitment strategy. A second set of responsibilities includes assisting with growth and maintenance of research data, including ensuring protocols and data elements are appropriately documented; this may include assisting with developing search, visualization, and harmonization tools. Does this position require Patient Care? No Essential Functions -Independently determines the suitability of study subjects. -Develops and implements recruitment strategies. -Participates in the design of research methodology. -Plans, performs, and designs statistical analyses. -Recommends protocol changes, writes protocols, and contributes to manuscripts. -Independently performs specialized projects. Qualifications Education Bachelor's Degree Related Field of Study required or Graduate Diploma Related Field of Study preferred Experience Related post-bachelor's degree research experience 3-5 years required Knowledge, Skills and Abilities - Ability to work more independently and as a team member. - High degree of computer literacy and analytical skills. - Ability to identify both technical and non-technical problems and develop solutions. - Ability to interpret acceptability of data results. - Highly proficient data management skills and working knowledge of data management systems. - Able to display initiative to introduce innovations to research study. - Excellent time management, organizational, interpersonal, written, and verbal communication skills. Additional Job Details (if applicable) Remote Type Hybrid Work Location 221 Longwood Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $ - $82,014.40/Annual Grade 6 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: 2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

• Designing and implementing clinical trial protocols, ensuring adherence to scientific and regulatory standards • Conducting data analysis and interpretation to derive insights that support study objectives • Collaborating with cross-functional teams to ensure effective study execution and data quality • Engaging with stakeholders to communicate findings and contribute to scientific discussions • Assisting in the preparation of regulatory submissions, study reports, and scientific publications

• Oversee clinical trial management workstreams, ensuring deliverables meet quality and timeline expectations. • Collaborate with cross-functional teams to design and implement effective clinical trial enrollment. • Collaborating with cross-functional teams to develop and implement comprehensive clinical trial protocols. • Overseeing and managing the day-to-day operations of clinical trials, ensuring compliance with regulatory standards. • Analyzing and interpreting clinical trial data, identifying trends, and providing insights to optimize study outcomes. • Proactively addressing challenges and implementing effective solutions to ensure the successful execution of clinical trials. • Communicating effectively with internal and external stakeholders to foster strong partnerships and facilitate smooth trial processes.

• Support the design, start-up, and execution of global clinical trials, ensuring adherence to protocol, regulatory requirements, and data integrity standards. • Contribute to development of clinical protocols, statistical analysis plans, investigator brochures, and regulatory documents, with focus on study endpoints, key efficacy outcomes, and safety assessments. • Collaborate with cross-functional teams to support endpoint strategy, event adjudication processes, and safety monitoring. • Participate in development and oversight of endpoint adjudication charters, safety monitoring plans, and Data Monitoring Committee (DMC) interactions. • Provide clinical input into data management plans, CRF design, and clinical data review, with focus on key study endpoints, efficacy and safety outcomes, and/or imaging or biomarker endpoints, as applicable. • Conduct ongoing clinical data review and signal detection, supporting identification and resolution of safety and data quality issues across global trial sites. • Support preparation and interpretation of interim analyses, database lock activities, and top-line data readouts. • Assist Development Lead and Clinical Scientist Director with medical monitoring activities and oversight of CROs, vendors, and adjudication committees. • Collaborate with clinical operations, biostatistics, safety, regulatory, and medical affairs teams to ensure successful delivery of clinical studies across relevant indications and endpoint strategies. • Contribute to clinical study reports, regulatory submissions, scientific publications, and presentations for internal and external stakeholders. • Identify operational or scientific risks and proactively implement mitigation strategies across cross-functional teams.