Role Description The Senior Clinical Trial Manager is responsible for the execution and management of assigned clinical studies while ensuring Good Clinical Practices (GCP) Compliance, high study quality, and timely completion. This position is responsible for assisting in meeting functional, organizational, and corporate goals for acoramidis (AG10) by providing successful management of clinical study teams and clinical trials. Responsibilities - Leads the Clinical Study Team for assigned projects; may lead one or more clinical studies, from concept to protocol, and achieve corporate objectives and key milestones such as First Patient In, Interim Analysis, Database lock, etc. - Manage external vendors and contract research organizations; may manage internal resources such as Clinical Research Associates (CRAs) and Clinical Trial Assistants (CTAs). - Prepare/Review/Approve study documents such as the Monitoring Manual, Study Operational Manual, Source Data Verifications Plan, and Laboratory Manual. - Coordinate and design study materials such as CRFs, patient diaries, study participation cards, and source documents. - Manage operational activities at the study level and monitoring activities (may include routine on-site clinical monitoring) at clinical study sites to assure adherence to GCP, Standard Operating Procedures (SOPs), and study protocols. - Negotiate and manage vendor work agreements and site contracts. Qualifications - Bachelor’s degree in a scientific discipline or equivalent is required; an advanced degree is preferred. - Requires at least eight years of biopharma industry experience (relevant clinical trials experience, in the biotechnology, pharmaceutical, CRO, medical device industry) with at least two years managing clinical trials. - Must have vendor management experience in clinical operations/development. - Strong verbal and written communication skills, can communicate strategic direction and relevant context so that employees at all levels understand their role in achieving success. - Ability to build and maintain strong working relationships within the department and cross-functionally to meet a project or corporate goal. - Experience with Microsoft Office Suite required (Word, Excel, Project, Outlook). - Must be able and willing to travel periodically. Benefits - Market-leading compensation. - 401(k) with employer match. - Employee Stock Purchase Program (ESPP). - Pre-tax commuter benefits (transit and parking). - Referral bonus for hired candidates. - Subsidized lunch and parking on in-office days. - 100% employer-paid medical, dental, and vision premiums for you and your dependents. - Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA). - Fertility & family-forming benefits. - Expanded mental health support (therapy and coaching resources). - Hybrid work model with flexibility. - Flexible, “take-what-you-need” paid time off and company-paid holidays. - Comprehensive paid medical and parental leave to care for yourself and your family. - People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility. - We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching. - We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities.

• Execute and own external data management activities for assigned clinical studies • Develop and maintain Data Transfer Agreements (DTAs) and external data specifications • Coordinate and perform test data transfers with hands-on QC • Import, validate, and reconcile external datasets • Collaborate with Clinical Operations, Biostatistics, and Regulatory teams • Support regulatory inspections as the external data management subject matter expert

• You own the end-to-end partner journey within the Seller Central / Partner Hub and continuously improve the self-service experience for marketplace partners. • You collect, structure and prioritize requirements from Business Development, Technical Integration, Customer Success and direct partner feedback. • You translate business requirements into clear user stories, problem statements and user flows while collaborating closely with Product and Tech teams. • You define and monitor relevant KPIs such as onboarding speed, self-service adoption, seller NPS and ticket reduction to drive continuous optimization. • You identify opportunities for automation and process improvements to reduce manual onboarding efforts and improve the partner experience.

• As a Partner Enablement Manager, you will play a key role in building a scalable enablement ecosystem that empowers our marketplace partners to independently and successfully use our platform. • You will work at the intersection of content, product, technical integrations and partner experience, creating modern learning and communication formats that drive real impact. • In this role, you will translate complex technical and operational processes into user-friendly and engaging content while continuously improving the partner onboarding journey.