Location: Cambridge United States Job Description: Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Patient Support Manager (PSM) to join our growing Market Access team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping Sickle Cell patients. The Sickle Cell Patient Support Manager is responsible for coordinating comprehensive care for patients living with sickle cell disease. This role focuses on improving patient outcomes through education, care coordination, access support, and collaboration with healthcare providers and community resources. The Patient Support Manager serves as a key advocate for patients, ensuring timely access to treatment, adherence to care plans, and a high-quality patient experience. The Patient Support Manager will report to the regional Senior Manager Patient Access and Reimbursement Services. What you will do: - Contribute to the success of a best-in-class patient services program to support Agios’ Commercial Vision Mission - Maintain long-term relationships with patients, caregivers, families, and HCPs to proactively identify and address new and ongoing barriers to access an ultra-rare drug - Fosters collaborative relationships with Agios field-based and home-office teams to ensure One Agios unified approach to supporting patient access and brand strategy - Exceed in delivering positive patient experience by assessing patient needs and develop action plans that identify and troubleshoot future access barriers to support treatment initiation and ensure continuation of the patient’s treatment journey - Help patients make connections with other patients and serve as the “face of Agios” at patient meetings and industry conferences - Effectively shares reimbursement and other knowledge with customers and internal team members through collaboration and consultation for complex patient case studies - Maintains comprehensive understanding of the access process, navigation of health care systems, insurance plans, payer trends, and internal/external patient and financial assistance programs - Apply program business rules and work instructions to deliver uniform, consistent and sustainable service experience for patients - Maintain confidentiality of patient health information and act in compliance with all laws, regulations and Agios policies. - Demonstrates and maintains a high level of business acumen, understanding of Agios’ business model, and the role of the patient support manager in commercializing the business and driving initiatives to meet company goals - Consistently leverages CRM reporting tools and data analytics to make strategic decisions about their territory and prioritize patient and customer needs - Is proficient in the use of Customer Relationship Management tool - Approaches patient and caregiver interactions with empathy, cultural humility, and an understanding of the lived experience and historical challenges faced by individuals with a rare disease - Applies a trauma‑informed approach to patient engagement, recognizing the impact of chronic pain, repeated healthcare interactions, and historical inequities on patient trust and decision‑making - Exceed in delivering a positive, dignified patient experience by building trust, actively listening, and addressing patient needs with compassion and urgency What you bring: - Bachelor’s degree required. Health Care/Social Work/Nursing (or related field) a plus. - Minimum of five (5) years of experience directly related to patient service or market access (e.g., case management) in the healthcare or pharmaceutical/biotech industry. Ultra-rare disease experience a plus. - Knowledge of private payer, Medicare Part D and Medicaid structure, systems, and reimbursement process - Knowledge of benefit verification and prior authorization process for oral products - Experience and proficiency in working with a Customer Relationship Management System, such as Salesforce.com - Ability to proficiently use Microsoft Excel, Outlook, and Word - Ability to work independently and manage competing priorities - Experience working in cross-functional teams and effective in influencing without authority - Possess strong written and verbal communication skills, exceptional listening, critical thinking, and problem solving - This position may require ability to travel within the US up to 15% Preferred Qualifications - Rare, ultra rare, or genetic disease experience - Located in the Mid South region Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description.. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $110,029 and $165,044 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Title: Patient Support Manager, Market Access (Mid Atlantic) Location: United States Job Description: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Patient Support Manager (PSM) to join our growing Market Access team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping Sickle Cell patients. The Sickle Cell Patient Support Manager is responsible for coordinating comprehensive care for patients living with sickle cell disease. This role focuses on improving patient outcomes through education, care coordination, access support, and collaboration with healthcare providers and community resources. The Patient Support Manager serves as a key advocate for patients, ensuring timely access to treatment, adherence to care plans, and a high-quality patient experience. The Patient Support Manager will report to the regional Senior Manager Patient Access and Reimbursement Services. What you will do: - Contribute to the success of a best-in-class patient services program to support Agios’ Commercial Vision Mission - Maintain long-term relationships with patients, caregivers, families, and HCPs to proactively identify and address new and ongoing barriers to access an ultra-rare drug - Fosters collaborative relationships with Agios field-based and home-office teams to ensure One Agios unified approach to supporting patient access and brand strategy - Exceed in delivering positive patient experience by assessing patient needs and develop action plans that identify and troubleshoot future access barriers to support treatment initiation and ensure continuation of the patient’s treatment journey - Help patients make connections with other patients and serve as the “face of Agios” at patient meetings and industry conferences - Effectively shares reimbursement and other knowledge with customers and internal team members through collaboration and consultation for complex patient case studies - Maintains comprehensive understanding of the access process, navigation of health care systems, insurance plans, payer trends, and internal/external patient and financial assistance programs - Apply program business rules and work instructions to deliver uniform, consistent and sustainable service experience for patients - Maintain confidentiality of patient health information and act in compliance with all laws, regulations and Agios policies. - Demonstrates and maintains a high level of business acumen, understanding of Agios’ business model, and the role of the patient support manager in commercializing the business and driving initiatives to meet company goals - Consistently leverages CRM reporting tools and data analytics to make strategic decisions about their territory and prioritize patient and customer needs - Is proficient in the use of Customer Relationship Management tool - Approaches patient and caregiver interactions with empathy, cultural humility, and an understanding of the lived experience and historical challenges faced by individuals with a rare disease - Applies a trauma‑informed approach to patient engagement, recognizing the impact of chronic pain, repeated healthcare interactions, and historical inequities on patient trust and decision‑making - Exceed in delivering a positive, dignified patient experience by building trust, actively listening, and addressing patient needs with compassion and urgency What you bring: - Bachelor’s degree required. Health Care/Social Work/Nursing (or related field) a plus. - Minimum of five (5) years of experience directly related to patient service or market access (e.g., case management) in the healthcare or pharmaceutical/biotech industry. Ultra-rare disease experience a plus. - Knowledge of private payer, Medicare Part D and Medicaid structure, systems, and reimbursement process - Knowledge of benefit verification and prior authorization process for oral products - Experience and proficiency in working with a Customer Relationship Management System, such as Salesforce.com - Ability to proficiently use Microsoft Excel, Outlook, and Word - Ability to work independently and manage competing priorities - Experience working in cross-functional teams and effective in influencing without authority - Possess strong written and verbal communication skills, exceptional listening, critical thinking, and problem solving - This position may require ability to travel within the US up to 15% Preferred Qualifications - Rare, ultra rare, or genetic disease experience - Located in the Central region Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description.. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $110,029 and $165,044 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Role Description You will be responsible for defining and executing Runware’s hardware and datacenter strategy, including GPU sourcing, server infrastructure, hosting partnerships, and long-term capacity planning. You will help the company scale its infrastructure globally while optimizing performance, reliability, and cost efficiency. This is a highly strategic role sitting at the intersection of engineering, operations, and business, with direct impact on the company’s ability to scale its AI platform. Responsibilities - Define and execute Runware’s hardware and compute infrastructure strategy. - Own the GPU procurement and supply strategy, including relationships with vendors and hosting providers. - Design and optimize server and datacenter infrastructure supporting AI inference workloads. - Evaluate and negotiate partnerships with datacenter providers, GPU vendors, and infrastructure partners. - Work closely with engineering teams to ensure infrastructure supports evolving product and model requirements. - Drive cost/performance optimization across hardware deployments. - Lead capacity planning to support rapid company growth and global infrastructure expansion. - Monitor industry trends across GPU hardware, AI infrastructure, and datacenter innovation. - Support the deployment of infrastructure across multiple regions and providers. - Help build the long-term roadmap for Runware’s global compute platform. Qualifications - Strong experience with GPU infrastructure, servers, or datacenter operations. - Experience managing large-scale compute infrastructure for cloud, AI, or high-performance workloads. - Background working with GPU vendors, hosting providers, or infrastructure partners. - Strong understanding of AI workloads and GPU performance optimization. - Experience negotiating infrastructure contracts or managing hardware procurement. - Ability to balance technical decisions with business and cost considerations. - Comfort working in a fast-moving startup environment. - Excellent communication skills and ability to collaborate across technical and business teams. Nice to Have - Experience working in AI infrastructure, cloud providers, or GPU hosting companies. - Experience building or scaling global compute infrastructure. - Background in HPC, cloud infrastructure, or datacenter operations. Benefits - Generous paid time off – vacation, sick days, public holidays. - Meaningful stock options – share in the upside you create. - Remote-first setup – work from home anywhere we can employ you. - Flexible hours – own your schedule outside core collaboration blocks. - Family leave – paid maternity, paternity, and caregiver time. - Company retreats – twice-yearly gatherings in inspiring locations.

Role Description The Country Manager – Thailand & Vietnam will lead the commercial growth, market expansion, and operational development of both markets, with full responsibility for building regional presence, strengthening existing team structures, and scaling the business significantly. This role is suited to a commercially driven leader with strong experience in brokerage, fintech, or financial services who can grow revenue, lead teams, build partnerships, and deliver market-specific strategies across Thailand and Vietnam. The position will play a critical role in expanding local market share, improving team performance, and growing the regional setup to 5x its current scale. Responsibilities - Develop and execute the growth strategy for Thailand and Vietnam, covering market expansion, client acquisition, revenue generation, and long-term business development. - Lead, manage, and scale the existing regional team across sales, business development, partnerships, and supporting functions, ensuring the structure is built to achieve 5x growth. - Own core commercial KPIs including accounts opened, deposits, trading volume, revenue, team productivity, and overall regional performance. - Build and strengthen strategic relationships with high-value clients, IBs, affiliates, partners, and other local business channels to accelerate market penetration. - Work closely with marketing, product, and regional leadership teams to localize go-to-market strategies, improve client conversion, and enhance retention across both countries. - Ensure strong execution standards across people leadership, budget control, reporting, compliance awareness, and operational effectiveness in line with business priorities. Qualifications - 8+ years of relevant experience in Leading Forex, CFD, brokerage, fintech, financial services, or a closely related trading environment. - Proven experience leading and scaling commercial teams, with strong people management and performance leadership capability. - Demonstrated success in market expansion, business development, and revenue growth within competitive regional markets. - Strong understanding of FX/CFD products, trader behaviour, client lifecycle management, and sales performance metrics. - Excellent commercial judgment, negotiation skills, stakeholder management, and the ability to build trusted external partnerships. - Fluent English communication skills, with the ability to operate in a fast-paced, target-driven, and cross-functional environment. Requirements - Direct experience managing Thailand and/or Vietnam markets within a brokerage, fintech, or trading business. - Existing network of IBs, affiliates, sales partners, or high-value clients across Southeast Asia. - Experience launching or scaling a market from early-stage growth into a more established regional operation. - Strong knowledge of digital acquisition channels, regional marketing strategy, and conversion-focused growth initiatives. - Familiarity with regulated financial products, compliance-sensitive environments, and cross-border stakeholder management. - Local language capability in Thai and/or Vietnamese would be a strong advantage. Additionally, we prefer candidates who speak Chinese or Cantonese.