Staff/Lead Site Reliability Engineer (SRE) San Francisco, California Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare. Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 500,000 patients worldwide. HeartFlow is transforming cardiovascular care with cutting-edge, non-invasive technology. We are launching a massive Platform Modernization initiative to power the next generation of our life-saving medical products. We're looking for an experienced Site Reliability Engineer (SRE) to join our cloud-native infrastructure team. You will work closely with our Platform engineers and development teams to ensure our critical systems are highly available, scalable, observable, and performant. If you thrive on eliminating toil, automating complex operations, and defining the standards for production excellence, we want to talk to you. Job Responsibilities As our Staff SRE, you'll be the primary expert responsible for our entire compute ecosystem. Your key responsibilities will include: As a Staff SRE, you'll operate at the highest level of technical expertise and influence. You won't just solve problems; you'll prevent them at a fundamental level across organizational boundaries. - Lead the design, implementation, and operation of reliable, scalable cloud infrastructure - Define and begin rollout of SLI/SLO standards across microservices - Develop self-service instrumentation tooling enabling engineering teams to own observability - Establish observability and monitoring using OSS toolchain - Serve as a technical escalation point for critical incidents, perform deep-dive root cause analyses (RCAs), and implement robust corrective measures to prevent recurrence. - Enhance our monitoring, logging, and tracing systems to provide comprehensive visibility into system health. - Set the technical direction and best practices for the entire SRE and engineering organization. Mentor mid-level and senior engineers on design patterns, operational rigor, and reliability principles. We're looking for a leader and a deep technical expert with a proven track record of solving the hardest scaling and reliability challenges. Required Qualifications - 8+ years of progressive experience in Site Reliability Engineering, Production Engineering, or a closely related role. - Deep expertise with: - AWS  - Kubernetes, Helm - Observability stack (Prometheus, Grafana, Mimir, Loki, Pixie, Tempo) - CI/CD systems (ArgoCD, Harness) - Fluency in at least one major scripting/programming language for automation and tooling (e.g., Python, Go, or Java). - Hands-on engineering mindset — able to instrument services directly, not just configure tooling - Track record of building or significantly improving incident detection and response systems - Have deep technical familiarity with Kubernetes ecosystems, containerization technologies, and modern IaC tooling (e.g., Terraform, Crossplane, or Operators) so you can effectively guide the team's technical decisions - Exceptional communication skills, capable of explaining complex technical issues to both technical and non-technical audiences. Nice-to-Have - Experience implementing Service Mesh technologies (e.g., Istio, Linkerd). - A strong understanding of security principles and practices in a cloud environment. - Certifications such as CKA (Certified Kubernetes Administrator) or CKAD (Certified Kubernetes Application Developer). A reasonable estimate of the base salary compensation range is $200,750 to $250,922, cash bonus, and equity. #LI-IB1 #LI-Hybrid