Sickle Cell Specialist, Sickle Cell Disease (Detroit) Location: Detroit, Ann Arbor, Grand Rapids, Milwaukee, Minneapolis, United States Remote Job Description: Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: We are seeking individuals with a demonstrated track record of success in launching rare diseases medicines and who are motivated by building durable markets in complex, underserved therapeutic areas. The Sickle Cell Specialist should possess an entrepreneurial “start-up” mentality and values consistent with the patient and science focused Agios culture. They will be energized by the opportunity to earn trust, advance disease education, and prepare the ecosystem for long-term impact which will lay the foundation for the success of Mitapivat and Agios’ pipeline of transformative rare genetic disease treatments. The Sickle Cell Specialist (SCS) will report to a Regional Business Director and will be responsible for raising awareness of Sickle Cell Disease (SCD) and the need for disease education in SCD and the treatment of hemolytic anemia. The SCS will have territory level goals focused on identifying appropriate patients, advancing disease education, and supporting treatment readiness in anticipation of a potential future approval. Additionally, the SCS will be responsible for raising awareness across their respective geographies in anticipation of the initial US approval of Mitapivat for Sickle Cell Disease. Territory to include these major markets: Detroit, Ann Arbor, Grand Rapids. This is a field-based role requiring consistent in-person engagement across priority accounts within the territory. What you will do: - As a Sickle Cell Specialist, you are the territory business owner, responsible for developing and executing a long-term market building strategy across your geography - Lead consistent, multi-touch disease education engagements to advance understanding of SCD pathophysiology, disease burden, and unmet need - Develop an integrated plan for your geography reflecting deep analysis, clear prioritization, and disciplined execution - Work with all field teams and marketing to ensure alignment on objectives, strategies, and communication - Develop credible, trust-based relationships with key customers and continue to build knowledge of the sickle cell marketplace - Collaborate with Regional Medical Affairs and Market Access colleagues to ensure seamless coordination and timely patient support - Advance appropriate patients toward treatment readiness while continuously assessing performance metrics and adapting strategies - Develop strong internal and external relationships to enable appropriate, compliant business partnerships - Ensure appropriate and compliant utilization of approved corporate, promotional and other resources to facilitate customer engagements - Represent Agios positively and professionally at company meetings and conferences, ensuring your activities are compliant with laws, regulations, policies and guidelines - Achieve or exceed sales forecasts and targets, within budget - Lead ad-hoc initiatives to contribute to the business as requested What Success Looks Like in this role: - Priority HCPs view you as a trusted SCD partner, not just a product representative - Disease education conversations deepen over time and lead to earlier identification of appropriate patients - Accounts are prepared to act efficiently once therapy is approved for appropriate patients - Cross‑functional partners rely on your insights to inform strategy and execution What you bring: - Bachelor’s degree required, Scientific degree a plus - Proven track record of success in Rare Disease sales; minimum 5 years’ experience in rare disease. - Sickle Cell/Hematology/Oncology sales experience preferred - Experience in building disease awareness and launching first in class therapies - Demonstrated business acumen with account management skills, data analysis and understanding, and competitive selling - Demonstrated ability to translate complex clinical and scientific concepts into credible, compliant dialogue - Demonstrated cross functional collaboration with internal stakeholders including marketing, medical affairs, market access, patient services, and sales operations - Demonstrated knowledge of the payer and clinical landscape, especially in specialty & rare diseases - Results-oriented with ability to thrive in a fast-paced, entrepreneurial environment - Ability to navigate ambiguity and drive results - Strong, resourceful, self-starter with an innovative mindset and ability to develop and execute new business solutions - Extraordinary commitment to customer experience and standards of excellence - Willingness to travel extensively across large geographies - Established relationships with Hematology/Oncology HCPs within designated geography strongly preferred - Prior experience launching rare disease products strongly preferred - Experience leading regional and/or national initiatives strongly preferred - Experience working in diseases with access challenges, health equity considerations, or historically underserved patient populations is strongly preferred Travel Requirements: Both virtual or in-person meetings are facilitated as needed and appropriate. Travel requirement will be an average of 50-60% within the territory focusing on the major market areas of Detroit, Milwaukee, and Minneapolis. Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific – Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Consistent in-person presence with priority accounts is expected. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $152,440 and $228,660 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators - Incentive design that recognizes both foundational market building and long-term value creation. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Role Description This is a remote position. Seeking a detail-oriented and highly analytical Registered Nurse (RN) to join our team in a HEDIS Abstraction role, supporting critical healthcare quality initiatives across Pennsylvania. While the home office is based in Harrisburg, this position is fully virtual and open to candidates located anywhere within the state. This role offers a unique opportunity for experienced RNs who are looking to step away from bedside care and apply their clinical expertise in a focused, data-driven environment that directly influences patient outcomes and healthcare performance. - Review and abstract clinical data from medical records in accordance with HEDIS measures. - Analyze documentation related to preventive care, chronic disease management, and behavioral health services. - Ensure all information is accurately captured and compliant with NCQA guidelines and measure specifications. - Utilize abstraction tools and electronic medical record systems to document findings. - Maintain audit readiness and ensure a high level of accuracy. - Consistently meet deadlines during peak reporting periods. - Impact healthcare quality scores, reimbursement, and public reporting. - Collaborate with healthcare providers, health plans, and internal quality teams to resolve discrepancies. - Manage workflow in a structured remote environment while maintaining performance expectations. This position is ideal for Registered Nurses seeking greater flexibility, a predictable schedule, and the opportunity to leverage their clinical knowledge in a non-patient-facing role. It provides exposure to healthcare quality improvement, compliance, and population health, helping you build specialized skills that are highly valued across the healthcare industry. Qualifications - Active RN license. - Strong understanding of medical terminology and clinical documentation. - Familiarity with coding systems such as ICD-10 and CPT (highly preferred). - Experience with electronic medical records. - Detail-driven and organized. - Comfortable working independently in a fully remote environment. Requirements - Ability to maintain high standards of accuracy and productivity.

Role Description The Direct Bill Commissions Specialist will: - Retrieve commission statements. - Post In-House and Outsourced Direct Bill Commissions. - Complete Revenue Tracking and Calculation logs daily. - Complete exception research and resolution. - Participate in month end closing. - Provide accounting support to financial accounting areas. A glimpse into your day: - Process benefits, personal, and/or commercial lines direct bill commissions. - Search customer and policy numbers and enter premiums and commissions received from insurance carriers. - Post via manual posting, commission download from the carrier, or through statement conversion. - Process Return Commission statements, ensuring funds have not already been paid to carriers. - Create Direct Bill (DB) entry and check request for payments to carriers when necessary. - Process all journal voucher entries needed to clear the Direct Bill Receivables GL account. - Manage the direct bill receivables report to ensure the ending balance is as close to zero as possible. - Maintain the Monthly Revenue Log including calculation columns and DB commission statement folders. - Communicate with carriers by email or phone to obtain missing commission statements. - Establish or ensure a working login(s) for each company website to pull commission statements. - Process statements received by email or mail. - Ensure all payments received during the month have corresponding statements received and are posted by month end. - Resolve discrepancies and exceptions with carriers and/or company personnel. - Reconcile Direct Bill General Ledger to the Direct Bill Revenue Log for month end closing. - Research and resolve Direct Bill posting issues with outsourcing company. - Act as primary contact for acquisitions following the data merge. - Complete special projects and other duties as assigned. Qualifications - High School Diploma or equivalent. - BA in Accounting, Finance, Economics, Business or Statistics preferred. - 2 years finance and accounting experience preferred. - Working knowledge of Microsoft applications, especially Word and Excel. - Working knowledge of website navigation, especially banking and insurance websites. - Basic knowledge of accounting rules, regulations, policies, and procedures reflective of the financial service industry. - Strong interpersonal skills; strong oral and written communication. - Strong problem solving, relationship management, and critical thinking skills. - Ability to prioritize multiple projects, meetings, and deadlines. - Willingness to assist internal and external customers with any concerns. - Ability to work independently and on a team. Benefits - Competitive pay. - A safe and healthy work environment provided by our robust benefit program including family health and wellness programs, 401K, employee assistance programs, paid time off, paid holidays, and more. - Career advancement and development opportunities.

Role Description OpenLoop’s mission is to bring care anywhere by powering telehealth solutions at scale. The Practice Authority Specialist is responsible for establishing, tracking, and submitting collaborative practice agreements (CPA) between healthcare providers, ensuring compliance with state regulations and organizational policies. This role serves as a vital link between clinicians, regulatory bodies, and internal stakeholders. - Manage Collaborative Practice Agreements (CPAs): Establish, submit, and track agreements for clinicians across multiple states, ensuring total alignment with varying state-specific regulations. - Monitor Compliance Lifecycles: Proactively track the status and renewal timelines of CPAs to ensure no lapse in provider practice authority. - Facilitate Stakeholder Relations: Act as a vital liaison between midlevel clinicians, collaborating physicians, and regulatory bodies to streamline agreement execution. - Educate Clinicians: Utilize internal resources to provide clear guidance to providers on complex regulatory requirements and onboarding processes. - System Maintenance: Leverage Jira, Excel, and GSuite to document activities and maintain an accurate, audit-ready database of all practice authority documents. - Other duties as assigned. Qualifications - Bachelor’s degree in Healthcare Administration, Business, or a related field. - 1+ years of experience in healthcare regulatory compliance, recruitment licensure, or collaborative practice management. - Interpersonal skills to simplify complex legal or regulatory concepts for clinicians and internal partners. - Thrive in task-based environments where tracking deadlines and managing documentation accuracy is paramount. - Experience with regulatory tracking systems, Excel, and GSuite; experience with Jira or similar tools is a plus. Benefits - Medical, Dental, and Vision plans - Flexible Spending/Health Savings Accounts - Flexible PTO - 401(k) + Company Match - Life Insurance, Pet insurance, and more