• Provide statistical support for Medical Affairs studies, including observational studies, real-world evidence (RWE) studies, and post-marketing and Phase IV studies • Contribute to study design, protocol development, and statistical analysis plans (SAPs) • Perform and/or oversee statistical analyses and ensure accuracy and quality of outputs • Collaborate with Medical Affairs, Clinical, Epidemiology, and HEOR teams • Interpret study results and contribute to clinical study reports, publications, and presentations • Ensure compliance with regulatory and internal standards • Support publication strategy and scientific communication activities • Mentor junior statisticians, if applicable

Role Description This is a remote position. We are seeking a detail-oriented and self-motivated Plumbing Estimator to manage our end-to-end bidding process for US-based construction projects. This is a remote role, aligned to US working hours, and well suited for experienced estimators based in South Africa who are interested in the US construction market. In this role, you will take ownership of plumbing estimates from opportunity identification through bid submission. You’ll work closely with US general contractors (GCs), analyze full construction plan sets, and deliver accurate, competitive estimates that help secure new work across commercial and residential projects. This position can be performed fully remotely, with estimating, takeoffs, GC communication, and bid management all handled online. Key Responsibilities - Identify and pursue new bid opportunities via GC portals, plan rooms, and direct outreach - Attend virtual pre-bid meetings and coordinate bid requirements - Review architectural, mechanical, and plumbing drawings; perform detailed takeoffs - Prepare accurate plumbing estimates using Excel and/or estimating software - Solicit pricing from suppliers and subcontractors; manage bid deadlines - Follow up with GCs, negotiate scope and pricing, and support bid closeout - Maintain a bid log and manage an active pipeline of opportunities Qualifications - Minimum 3+ years of plumbing estimating experience (commercial experience preferred) - Strong ability to read and interpret full construction plan sets - Proficiency with takeoff/estimating tools such as Bluebeam, OST, or similar - Understanding of US plumbing systems (DWV, water service, gas, underground) - Willingness to work US hours and collaborate with US-based stakeholders - Self-starter with strong organization and time management skills - Familiarity with US plumbing codes and standards Nice to Have - Prior experience estimating US-based projects Benefits - Competitive Salary - Completely Remote Position

• Develop scientific relationships with hematology thought leaders, investigators, and treatment centers focused on multiple myeloma and related hematologic malignancies. • Serve as Karyopharm’s scientific representative and facilitate balanced, compliant scientific exchange. • Gather and communicate medical insights, treatment trends, competitive intelligence, and unmet needs. • Support clinical trial awareness, site identification, and investigator engagement activities in partnership with Clinical Development. • Support investigator-sponsored research and scientific collaboration opportunities. • Participate in advisory boards, congresses, steering committees, and medical education initiatives. • Partner closely with Medical Affairs, Clinical Development, Commercial, Market Access, and HEOR teams. • Mentor less experienced MSLs and contribute to special projects as assigned.

• Validate documentation accuracy and ensure financial and funding readiness. • Create Sales Orders (SO) in LN. • Perform final accuracy checks on all received documentation. • Identify financial or system issues prior to installation execution. • Review all received documentation for completeness and accuracy. • Escalate documentation accuracy concerns as necessary. • Maintain system integrity by following established ERP entry standards. • Validate funding method, payment status, and financing details for completeness. • Ensure consistency between upstream systems and LN. • Manage assigned ERP entry queue to meet SLA expectations. • Maintain detailed system notes and documentation to support audits or corrections.