Amgen logo
Amgen

#WeareBiotech

Principal Data Scientist - Optimization

Data ScientistData ScientistFull TimeRemoteLeadTeam 10,001+Since 1980H1B SponsorCompany SiteLinkedIn

Location

United States

Posted

99 days ago

Salary

$160K - $217K / year

Seniority

Lead

Job Description

Principal Data Scientist - Optimization

Amgen

Career Category Information Systems Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Principal Data Scientist - Optimization What you will do We are seeking a Principal Data Scientist, Optimization to join the Forecasting team, within the AI & Data organization. This role will lead the development, validation and deployment of advanced optimization models and decision-support solutions to guide strategic and operational decisions and help Amgen delivers on its “every patient, every time” mandate. This leader will partner across Commercial, Operations, Supply Chain, Manufacturing, Finance, and Technology to transform Amgen’s approach to operational decision making through rigorous analytical methods. The role is particularly well suited to a creative problem solver with deep expertise in mathematical optimization, including linear, nonlinear and mixed-integer programming, who is excited about applying these methods to hard problems in multi-echelon supply chain design, capacity allocation, and pricing/trade-off optimization. Key Responsibilities - Design, build and deploy optimization models using linear, nonlinear and mixed integer programming techniques to support high value business decisions. - Develop optimization solutions for challenging supply chain and commercial problems such as capacity allocation, supply planning, inventory optimization, portfolio tradeoffs, and price / margin optimization. - Partner with forecasting, simulation, and analytics teams to incorporate uncertainty, demand scenarios, and operational variability into optimization-based decision frameworks. - Own the end-to-end modeling lifecycle, including problem framing, prototype development, data analysis, model formulation, calibration, validation, testing, deployment, monitoring, and model explainability. - Architect and develop decision-support tools and self-service applications that enable business leaders to evaluate tradeoffs and respond rapidly to changing market and operational conditions. - Collaborate with cross-functional teams in Commercial, Operations, Finance, and Technology to ensure optimization solutions are integrated into critical business workflows and planning processes. - Develop a holistic understanding of Amgen’s systems and processes in relation to industry challenges and broader trends to identify opportunities and risks. - Evaluate emerging methods in optimization, reinforcement learning, and AI, and assess where they can complement classical operations research approaches. - Establish optimization as a rigorous, scalable capability across the organization, while mentoring junior team members and setting standards for technical excellence. Basic Qualifications - Doctorate degree and 2 years of data science in enterprise environments experience OR - Master’s degree and 4 years of data science in enterprise environments experience OR - Bachelor’s degree and 6 years of data science in enterprise environments experience OR - Associate’s degree and 10 years of data science in enterprise environments experience OR - High school diploma / GED and 12 years of data science in enterprise environments experience Preferred Qualifications - 8+ years applying operations research, data science or machine learning algorithms in an enterprise environment with demonstrated principal-level influence or equivalent depth of expertise. - Deep expertise in mathematical optimization including linear, non-linear, and mixed-integer programming, constrained optimization and scenario-based optimization. - Demonstrated experience building and deploying models that drive measurable business value in areas such as supply chain, manufacturing, logistics, pricing, or resource allocation. - Strong understanding of Python, SQL, with hands-on experience using frameworks such as Pyomo, PuLP, OR-Tools, Gurobi or equivalent. - Strong communication and story-telling skills, with demonstrated ability to simplify complex concepts and influence executive decision making. - Exceptional stakeholder management skills that can drive alignment on, relationships, and metrics, and communicate tradeoffs clearly. - An intellectually curious self-starter who is able to take ambiguous problems and build robust solutions from 0 to 1 - Experience building and scaling optimization platforms or decision-support systems for biotech, pharma, healthcare, manufacturing, retail, or consumer goods applications. - Familiarity with stochastic optimization, robust optimization, simulation-optimization, decomposition methods, heuristics, or metaheuristics for large-scale decision problems. - Exposure to reinforcement learning or approximate dynamic decisioning methods. - Knowledge of healthcare or biotech commercial concepts, including payer/provider dynamics, formulary/coverage considerations, or launch planning constraints What You Can Expect Of Us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: - A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts - A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan - Stock-based long-term incentives - Award-winning time-off plans - Flexible work models, including remote and hybrid work arrangements, where possible Apply now for a career that defies imagination Objects in your future are closer than they appear. Join us. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. .Salary Range 160,896.50USD -217,683.50 USD

Related Categories

Related Job Pages

More Data Scientist Jobs

DICK'S Sporting Goods logo

Lead Data Scientist, Search

DICK'S Sporting Goods

Headquartered in Coraopolis, Pennsylvania, DICK’S Sporting Goods offers sports fans and enthusiasts a “big store” selection of name-brand sports equipment

Data Scientist99 days ago

• lead design and implementation of advanced algorithms • developing & optimizing ranking algorithms • search personalization algorithms • collaborating with data & search engineers • collaborating with software engineers and architects • developing and implementing tools & processes for monitoring performance • collaboration with analytics teams for experimentation & A/B testing • staying updated with advancements in AI, ML, & search technologies • mentoring junior scientists and engineers

United States
$95.2K - $158.8K / year
Job Closed

Position Summary: MedReview is looking for a talented and experienced Data Scientist to join our dynamic team. As a part of our team, you will leverage your analytical skills and expertise in machine learning to extract insights from complex datasets and drive data-driven decision-making across our organization. You will collaborate closely with cross-functional teams to develop predictive models, uncover actionable insights, and solve challenging business problems. As part of a global team of developers and analysts, the Data Scientist will work with a larger team to design, build, validate, refine, and operationalize models. This position will sit in Austin, Texas. However, for the right fit, we may consider remote. Responsibilities: - Problem Identification: Collaborate with stakeholders to identify business challenges that can be solved through data analysis. - Data Collection & Preparation: Gather data from various sources (SQL databases, APIs, web scraping), then clean and "wrangle" it to ensure accuracy for modeling. - Model Development: Design and implement algorithms and predictive models using machine learning techniques to forecast outcomes or categorize information. - Exploratory Data Analysis (EDA): Analyze datasets to uncover hidden patterns, trends, and anomalies. - Communication & Visualization: Translate technical findings into "data stories" using tools like Tableau or Power BI to influence executive decisions. Qualifications: - Master’s degree or bachelors degree and equivalent experience in a quantitative field (Math, CS, Stats) - Programming: Proficiency in Python or R along with SQL for database querying. - Mathematics & Statistics: Strong foundation in linear algebra, calculus, and statistical modeling. - Machine Learning: Experience with frameworks like TensorFlow, PyTorch, or scikit-learn. Soft Skills: Critical thinking, curiosity, and the ability to explain complex concepts to non-technical audiences. Experience working with global and remote teams

United States

Senior Data Scientist, Acquisition Marketing

PrizePicks

PrizePicks is the fastest-growing sports company in North America according to the 2023 Inc. 5000 rankings, two years running, and the largest independent skill-based fantasy sports operator in the country.

Data Scientist99 days ago
Full TimeRemoteTeam 201-500H1B No Sponsor

• Own end-to-end media modeling (MMM), from data preparation and model development, to validation, calibration, and stakeholder delivery • Design, launch, and maintain incrementality testing frameworks, in partnership with paid media partners, including geo-holdout and platform-native lift study designs • Translate model outputs into actionable budget allocation and channel investment recommendations • Partner with channel leads to develop and maintain a structured learning agenda across paid media • Automate recurring measurement processes to improve accuracy, scalability, and speed-to-insight • Contribute to raising the analytical bar across the team through code review, documentation, and knowledge sharing

United States
$120K - $170K / year
Job Closed
Optum logo

Sr Data Scientist - Remote

Optum

Optum, part of the UnitedHealth Group family of businesses, is a global organization that delivers care, aided by technology to help millions of people live healthier lives. The work you do with our team will directly improve health outcomes by connecting people with the care, pharmacy benefits, data and resources they need to feel their best. Here, you will find a culture guided by inclusion, talented peers, comprehensive benefits and career development opportunities. Come make an impact on the communities we serve as you help us advance health optimization on a global scale. Join us to start Caring. Connecting. Growing together. At Optum, we support your well-being with an understanding team, extensive benefits and rewarding opportunities. By joining us, you’ll have the resources to drive system transformation while we help you take care of your future. We recognize the power of connection to drive change, improve efficiency and make a difference in health care. Join a team where your skills and ideas can make an impact and where collaboration is key to creating technology that produces healthier outcomes.

Data Scientist99 days ago
Full TimeRemoteTeam 160,000Since 2011

Requisition Number: 2357144 At UnitedHealthcare, we're simplifying the health care experience, creating healthier communities and removing barriers to quality care. The work you do here impacts the lives of millions of people for the better. Come build the health care system of tomorrow, making it more responsive, affordable and optimized. Ready to make a difference? Join us to start Caring. Connecting. Growing together A Senior Data Scientist with a general analytics focus, acting as a versatile contributor across EAR projects impacting the UHC COVE. This role functions as a primary contributor on data science efforts, complementing specialized AI roles by focusing on broad data analysis, statistical modeling, and cross-functional analytic support. It requires an advanced understanding of data and analytic techniques, plus the flexibility to prepare and shape data for analysis. You'll enjoy the flexibility to work remotely * from anywhere within the U.S. as you take on some tough challenges. For all hires in the Minneapolis or Washington, D.C. area, you will be required to work in the office a minimum of four days per week. Primary Responsibilities: - Exploratory Data Analysis (EDA): Dive deep into project datasets to uncover patterns, trends, and insights. Conduct thorough exploratory analyses that inform project direction or hypothesis generation, identifying key statistics and relationships in the data that drive decision-making - Feature Engineering & Data Preparation: Create and refine features for use in machine learning models or reporting. Work on combining data from multiple sources, cleaning and transforming raw data into structured formats (with help from data engineers when needed). Ensure that analytic datasets are comprehensive and of high quality for downstream use - Statistical Modeling & Insights: Develop statistical models or simpler machine learning models to solve a variety of project needs beyond the primary AI components. This could include predictive analytics (e.g., regression models for trend analysis), segmentation/clustering to understand different user or patient groups, or A/B test analysis for pilot interventions. Interpret model results and validate their accuracy and reliability - Business Intelligence & Reporting: Translate data findings into actionable insights for business stakeholders. Build dashboards, visualizations, or custom reports that track key metrics for the project. Present analytical results in clear business terms, and make recommendations based on data (e.g., identifying areas of improvement in program outcomes or user engagement metrics) - Collaboration & Support: Work closely with other team members to support overall project goals. Provide analytical assistance such as validating the main AI model outputs, performing deep-dive analyses when anomalies arise, or answering ad-hoc analytical questions from leadership. Also collaborate with data engineers to ensure that data pipelines align with analytical requirements (for example, suggest additional data sources or transformations that could enhance model performance) You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in. Required Qualifications: - Analytics Experience: 5+ years in data science, analytics, or related fields with demonstrable impact. Solid background in analyzing complex datasets and building models or analytical solutions. Experience should cover end-to-end analytics: gathering requirements, data acquisition, analysis/modelling, and delivering results - Proven Technical Skills: Proficiency in programming for data analysis (Python or R) and solid SQL capabilities for querying databases. Comfort with relevant libraries and tools (pandas, numpy, matplotlib or ggplot2, etc. for analysis; scikit-learn or similar for modeling). Solid understanding of statistical concepts (e.g., significance testing, distributions, regression analysis) and when to apply them - Data Handling Experience: Experience working with large-scale or complex data (such as claims or transactional data, etc.). Able to write efficient code or queries to manipulate and aggregate data. Familiarity with data warehousing concepts and possibly big data tools (like Hadoop/Spark) is helpful to manage volume - Proven Problem-Solving & Communication Skills: Excellent analytical thinking with the ability to break down ambiguous problems into solvable parts. Attention to detail in validating results. Solid written and verbal communication skills to explain findings to non-technical stakeholders and document methodologies clearly Preferred Qualifications: - Data Engineering Experience: Experience with or exposure to data engineering tasks - Big Data Technologies Experience: Familiarity with Apache Spark for data processing. Ability to leverage cluster computing for speeding up large data analysis - Domain Insight Experience: Background in healthcare data or operational analytics in health services. Knowledge of healthcare concepts (like patient vitals, claims, clinical metrics) - Advanced Analytics Methods Experience: Experience in specialized areas like natural language processing (NLP), time-series analysis, or geospatial analysis, depending on project needs, is an added advantage *All employees working remotely will be required to adhere to UnitedHealth Group's Telecommuter Policy Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The salary for this role will range from $91,700 to $163,700 annually based on full-time employment. We comply with all minimum wage laws as applicable. Application Deadline: This will be posted for a minimum of 2 business days or until a sufficient candidate pool has been collected. Job posting may come down early due to volume of applicants. At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission. UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. UnitedHealth Group is a drug - free workplace. Candidates are required to pass a drug test before beginning employment.

Minnesota
$91.7K - $163.7K / year
Job Closed