Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting to the Executive Director of Field Medical Affairs, the Sr. Director will manage and coach a lung regional field medical team, oversee the regional field implementation plan and develop, deploy, and monitor key performance indicators and encourage individual professional development goals across the team. You will drive regional thought leader engagement strategy, foster scientific exchange, and lead insight generation strategies. Importantly, you will foster and identify opportunities to collaborate across functions and be instrumental in launch planning and execution. We are seeking a highly motivated and experienced leader to join our team as a Lung Regional Manager of Medical Science Liaisons. Key aspects of this front-line manager role will include: developing, mentoring, and coaching a team of MSL direct reports across approximately one half of the country. Required Skills, Experience and Education: - Collaborates with Field Medical Executive Director to build the Lung Revolution Medicines Field Medical Team (recruiting, hiring, and onboarding). - Provides critical input into Lung Field Medical Team strategic and tactical plans, overseeing execution of plans across aligned region. - Assists in the development of new field medical processes such as medical insight reporting, territory planning, congress coverage, investigator-sponsored research, etc. - Fosters a culture of empowerment, collaboration, and focus on patient impact across regional and national field medical teams. - Mentors, coaches and identifies opportunities for professional development for each MSL direct report. - Oversees execution of stakeholder engagement strategy across regional and community healthcare providers, including academic institutions and community centers across the aligned region to ensure timely and accurate scientific communication. - Monitors key performance indicators across region; deliver and communicate reports and trends to senior leadership as needed. - Identifies opportunities to support compliant and effective cross-functional collaboration across Clinical Development, Medical Affairs and Commercial teams, as needed and appropriate. - In collaboration with Clinical Development and Clinical Operations, develop and lead efforts to develop site identification/recommendation and clinical trial support plans. - Exhibits significant leadership experience in the pharmaceutical industry with the ability to work independently and collaboratively in cross functional team environment. - Encourages collaboration, innovation and new ideas while integrating information from various sources. - Demonstrates ability to develop and foster relationships with internal and external stakeholders. - Drives results; creates and nurtures a performance-based culture of continuous improvement, addressing concerns and conflict proactively. - Proven leadership, problem-solving and conflict resolution skills. - Highly effective presentation, communication, emotional intelligence, and interpersonal skills. Preferred Skills: - Advanced, medical/scientific doctoral level degree required: MD, PharmD, PhD. - Demonstrated ability to create departmental capabilities, processes, and procedures to ensure alignment with desired outcomes. - 10+ years of experience in the Pharmaceutical or Biotech Industry with Medical Affairs. - 5+ years of experience in a leadership role managing Field Medical teams. - 5+ years of lung targeted therapy experience. - Global product launch experience. - Demonstrated expertise in oncology. - Demonstrated experience recruiting, hiring, and retaining Field Medical talent. - Demonstrated leadership skills (proactive, strategic, creates a highly accountable team culture, provides clear direction), project management and organizational skills, with the ability to evaluate competing priorities to arrive at an appropriate decision. - Collaborative, team-based approach; ability to network and partner with internal and external stakeholders, including medical thought-leaders and a wide range healthcare professionals. - Thorough understanding of applicable regulatory requirements for field-based personnel and PhRMA guidelines, including geographic regulatory related guidelines. - Demonstrated in-depth knowledge of Field Medical best practices. - Experience in recruiting, on-boarding, managing, coaching, and retaining talent. - Effective oral, written, and interpersonal skills required. #LI-Remote #LI-VN1 The base pay salary range for this full-time position is listed below. Please note that base pay salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. In addition, some positions may include eligibility to earn commissions/bonus based on company and/or individual performance. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, field kit benefits, or any other form of compensation and field kit benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $268,000—$295,000 USD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting to the Executive Director of Field Medical Affairs, the Sr. Director will manage and coach a lung regional field medical team, oversee the regional field implementation plan and develop, deploy, and monitor key performance indicators and encourage individual professional development goals across the team. You will drive regional thought leader engagement strategy, foster scientific exchange, and lead insight generation strategies. Importantly, you will foster and identify opportunities to collaborate across functions and be instrumental in launch planning and execution. We are seeking a highly motivated and experienced leader to join our team as a Lung Regional Manager of Medical Science Liaisons. Key aspects of this front-line manager role will include: developing, mentoring, and coaching a team of MSL direct reports across approximately one half of the country. Required Skills, Experience and Education: - Collaborates with Field Medical Executive Director to build the Lung Revolution Medicines Field Medical Team (recruiting, hiring, and onboarding). - Provides critical input into Lung Field Medical Team strategic and tactical plans, overseeing execution of plans across aligned region. - Assists in the development of new field medical processes such as medical insight reporting, territory planning, congress coverage, investigator-sponsored research, etc. - Fosters a culture of empowerment, collaboration, and focus on patient impact across regional and national field medical teams. - Mentors, coaches and identifies opportunities for professional development for each MSL direct report. - Oversees execution of stakeholder engagement strategy across regional and community healthcare providers, including academic institutions and community centers across the aligned region to ensure timely and accurate scientific communication. - Monitors key performance indicators across region; deliver and communicate reports and trends to senior leadership as needed. - Identifies opportunities to support compliant and effective cross-functional collaboration across Clinical Development, Medical Affairs and Commercial teams, as needed and appropriate. - In collaboration with Clinical Development and Clinical Operations, develop and lead efforts to develop site identification/recommendation and clinical trial support plans. - Exhibits significant leadership experience in the pharmaceutical industry with the ability to work independently and collaboratively in cross functional team environment. - Encourages collaboration, innovation and new ideas while integrating information from various sources. - Demonstrates ability to develop and foster relationships with internal and external stakeholders. - Drives results; creates and nurtures a performance-based culture of continuous improvement, addressing concerns and conflict proactively. - Proven leadership, problem-solving and conflict resolution skills. - Highly effective presentation, communication, emotional intelligence, and interpersonal skills. Preferred Skills: - Advanced, medical/scientific doctoral level degree required: MD, PharmD, PhD. - Demonstrated ability to create departmental capabilities, processes, and procedures to ensure alignment with desired outcomes. - 10+ years of experience in the Pharmaceutical or Biotech Industry with Medical Affairs. - 5+ years of experience in a leadership role managing Field Medical teams. - 5+ years of lung targeted therapy experience. - Global product launch experience. - Demonstrated expertise in oncology. - Demonstrated experience recruiting, hiring, and retaining Field Medical talent. - Demonstrated leadership skills (proactive, strategic, creates a highly accountable team culture, provides clear direction), project management and organizational skills, with the ability to evaluate competing priorities to arrive at an appropriate decision. - Collaborative, team-based approach; ability to network and partner with internal and external stakeholders, including medical thought-leaders and a wide range healthcare professionals. - Thorough understanding of applicable regulatory requirements for field-based personnel and PhRMA guidelines, including geographic regulatory related guidelines. - Demonstrated in-depth knowledge of Field Medical best practices. - Experience in recruiting, on-boarding, managing, coaching, and retaining talent. - Effective oral, written, and interpersonal skills required. #LI-Remote #LI-VN1 The base pay salary range for this full-time position is listed below. Please note that base pay salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. In addition, some positions may include eligibility to earn commissions/bonus based on company and/or individual performance. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, field kit benefits, or any other form of compensation and field kit benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $268,000—$295,000 USD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Medical Director, Gastrointestinal & Inflammation in our Cambridge, MA office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. POSITION OBJECTIVES: Principal responsibilities include: - Serves as Global Safety Lead (GSL) and the Company-wide patient safety expert for assigned pharmaceutical / biological / drug-device combined products, accountable for the safety strategy and major safety deliverables for each assigned product. - Leads GPSE Safety Team (GST) and Safety Management Team (SMT) for assigned compounds and products. - Represents the cross-functional program team as a product safety profile and risk mitigation expert for internal (e.g., Takeda Safety Board) and external (e.g., Independent Data Monitoring Committee) stakeholders. - Manages cross-functional assessment of benefit-risk profile and communication of safety information for assigned compounds and products. POSITION ACCOUNTABILITIES: - Analyze and interpret safety data from various sources including non-clinical, clinical, post-marketing and scientific literature. - Conduct signal detection, monitoring, evaluation, interpretation, and management for assigned compounds and products. - Develop strategy for and lead preparation of responses to safety-related inquiries from regulatory agencies and ethics committees. - Ensure communication of all safety information that may impact the benefit-risk profile of assigned products to senior management. - Provide medical safety expertise, medical interpretation, review, and authorship of appropriate sections for critical documents (e.g., protocols and amendments, ICFs, IBs, IMPDs, clinical research reports, Health Hazard Evaluations, Signal Evaluation Reports, INDs, NDAs, BLAs, and CTAs) in collaboration with cross-functional colleagues. - Provide patient safety input to the clinical development program for assigned products and development compounds, and represent GPSE on internal governance bodies for study protocols, statistical analysis plans and other clinical study-related documents as applicable. - Manage benefit-risk profile, including authoring and updating of the benefit-risk documents, e.g., RMPs, for assigned compounds and products. - Collaborate and communicate safety issues with other functional areas such as Clinical Development, Regulatory Affairs, Quality Assurance, Medical Affairs, Marketing, Manufacturing, and Legal. - Interact with Regulatory Authorities as part of a cross-functional team to submit and defend regulatory inquires, MAAs, NDAs, and BLAs. - Ensure up-to-date representation of safety information in Company Core Data Sheet (including Reference Safety Information) and Investigator Brochure, as well as other labeling documents. - Demonstrate knowledge of local and global health authority requirements. - Support GPSE in the maintenance of a highly effective global safety organization in full compliance to worldwide regulations. - Train and mentor Pharmacovigilance Physicians and Specialists. - Maintain professional knowledge and accreditation by active participation in continuing medical education activities, and fosters a community of continual learning. EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS: - M.D. or D.O. or internationally recognized equivalent, with direct clinical experience in patient care following post-graduate training and appropriate grounding and knowledge of general medicine. Board certification and licensure preferred. - At least 5 years of experience in pharmaceutical industry within Drug Safety/Pharmacovigilance, with both investigational and marketed products. - At least 3 years of experience with aggregate reporting, safety surveillance, signal management and/or risk management. - Knowledge and understanding of national and international PV and regulatory guidelines. Travel Requirements: - Local and international travel across Takeda sites may be required. This position is currently classified as “ remote” in accordance with Takeda’s Hybrid and Remote Work policy. Empowering Our People to Shine Discover more at takedajobs.com No Phone Calls or Recruiters Please. #LI-JV2 Locations Massachusetts - Virtual Worker Type Employee Worker Sub-Type Regular Time Type Full time

You could be the one who changes everything for our 28 million members as a clinical professional on our Medical Management/Health Services team. Centene is a diversified, national organization offering competitive benefits including a fresh perspective on workplace flexibility. Position Purpose: Assist the Chief Medical Director to direct and coordinate the medical management, quality improvement and credentialing functions for the business unit. - Provides medical leadership of all for utilization management, cost containment, and medical quality improvement activities. - Performs medical review activities pertaining to utilization review, quality assurance, and medical review of complex, controversial, or experimental medical services, ensuring timely and quality decision making. - Supports effective implementation of performance improvement initiatives for capitated providers. - Assists Chief Medical Director in planning and establishing goals and policies to improve quality and cost-effectiveness of care and service for members. - Provides medical expertise in the operation of approved quality improvement and utilization management programs in accordance with regulatory, state, corporate, and accreditation requirements. - Assists the Chief Medical Director in the functioning of the physician committees including committee structure, processes, and membership. - Conduct regular rounds to assess and coordinate care for high-risk patients, collaborating with care management teams to optimize outcomes. - Collaborates effectively with clinical teams, network providers, appeals team, medical and pharmacy consultants for reviewing complex cases and medical necessity appeals. - Participates in provider network development and new market expansion as appropriate. - Assists in the development and implementation of physician education with respect to clinical issues and policies. - Identifies utilization review studies and evaluates adverse trends in utilization of medical services, unusual provider practice patterns, and adequacy of benefit/payment components. - Identifies clinical quality improvement studies to assist in reducing unwarranted variation in clinical practice in order to improve the quality and cost of care. - Interfaces with physicians and other providers in order to facilitate implementation of recommendations to providers that would improve utilization and health care quality. - Reviews claims involving complex, controversial, or unusual or new services in order to determine medical necessity and appropriate payment. - Develops alliances with the provider community through the development and implementation of the medical management programs. - As needed, may represent the business unit before various publics both locally and nationally on medical philosophy, policies, and related issues. - Represents the business unit at appropriate state committees and other ad hoc committees. - May be required to work weekends and holidays in support of business operations, as needed. Education/Experience: - Medical Doctor or Doctor of Osteopathy. - Utilization Management experience and knowledge of quality accreditation standards preferred. - Actively practices medicine. - Course work in the areas of Health Administration, Health Financing, Insurance, and/or Personnel Management is advantageous. Experience treating or managing care for a culturally diverse population preferred. License/Certifications: - Board certification in a medical specialty recognized by the American Board of Medical Specialists or the American Osteopathic Association’s Department of Certifying Board Services. - Certification in Internal or Family Medicine specialty , preferred. - Current state license as a MD or DO without restrictions, limitations, or sanctions from government programs. Pay Range: $236,500.00 - $449,300.00 per year Centene offers a comprehensive benefits package including: competitive pay, health insurance, 401K and stock purchase plans, tuition reimbursement, paid time off plus holidays, and a flexible approach to work with remote, hybrid, field or office work schedules. Actual pay will be adjusted based on an individual's skills, experience, education, and other job-related factors permitted by law, including full-time or part-time status. Total compensation may also include additional forms of incentives. Benefits may be subject to program eligibility. Centene is an equal opportunity employer that is committed to diversity, and values the ways in which we are different. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or other characteristic protected by applicable law. Qualified applicants with arrest or conviction records will be considered in accordance with the LA County Ordinance and the California Fair Chance Act