• Directly manage and develop field sales representatives across your region • Develop and efficiently implement the agent onboarding and training plans, tools and materials. • Work to proactively identify and elevate areas of opportunity for betterment to our agent facing systems and provisioning • Work with the Senior Director and other resources to establish staffing needs to grow production to goals • Establish and facilitate the agent identification and invitation process for state entry and expansion • Partner closely with the product, underwriting and sales support leaders to ensure communication and roadmaps remain aligned • Identifies options for innovative and practical solutions with go-to-market strategies across both personal and broad reach sales strategies for commercial and personal lines products • Partner closely with the Agile transformation and Product organization to ensure adoption of and leveraging best practices across other areas of the organization • Ensure consistent visibility with channel strategy OKR’s and KPI’s • Regularly monitors Agency onboarding and enablement, collecting and elevating opportunities to improve the agent experience, driving preference • Partners closely with senior leadership to monitor budget, forecasting and resource planning while finding opportunities for budget efficiencies • Facilitates talent management and calibration sessions in preparation for performance management.

• Partner with product leaders to help define and refine the IRM SaaS platform product strategy • Translate strategic priorities into executable roadmaps and cross-functional initiatives • Support prioritization decisions across platform capabilities, modernization efforts, and growth initiatives • Help ensure alignment across product, engineering, architecture, and delivery teams • Partner with the platform engineering leader to shape technology strategy • Drive strategic planning around architecture evolution, platform modernization, and engineering transformation • Lead enterprise-scale transformation initiatives across the product and technology organization • Drive migration programs, technology rationalization efforts, and other strategic change initiatives • Oversee platform release trains, release governance, and cross-functional release readiness across the organization • Champion adoption of AI tools across software development workflows, including design, coding, testing, documentation, and delivery.

Job Description General Summary: The Director, Clinical Pharmacology leads strategic, scientific and operational aspects at a program level. This role represents the department on strategic and operational cross-functional program teams and will be responsible for the development of clinical pharmacology plans; assists in departmental management through program reviews and collaborative decision-making; supervises asset leads, provides career development; routinely co-leads cross-functional efforts and leads department initiatives. Key Duties and Responsibilities: - Guides metabolic, co-dosing and drug-drug interaction issues, collaborating closely with cross functional colleagues - Co-leads or serves on cross-functional committees and/or contributes to or leads departmental initiatives - Creates protocol concepts and guides protocol start-up including site initiations and investigator meetings - Oversees and contributes to regulatory and safety documents - Contributes to clinical pharmacology summary documents - Guides PK analyses - Performs PK/PD or exploratory analyses and guides PK/PD modeling or simulations as appropriate - Provides management and career development to staff - Assists in recruitment and hiring - As a people manager within the organization, may have financial accountabilities and human resource responsibilities for assigned staff Knowledge and Skills: - Knowledge expert in Clinical Pharmacology - Effective leadership skills to drive performance and provide career development opportunities to staff - Critical thinking skills, with keen scientific and development judgment - Experience planning and executing Clinical Development Plans for new clinical entities particularly as it applies to the discipline of Clinical Pharmacology - Experience conducting and supervising clinical studies such as drug-drug interaction, special population or bioavailability - Experience conducting and supervising non-compartmental pharmacokinetic (PK) and PK/pharmacodynamic analyses - Experience with a range of clinical studies including first-in-human, proof-of-concept and registrational studies - Experience contributing to clinical and regulatory documents such as the Investigator’s Brochure and contributing to regulatory correspondence - Experience working on teams and in a matrix environment Education and Experience: - Ph.D. or Pharm D (or equivalent degree) in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 10+ years of relevant post-doctoral employment experience, or - Masters Degree (or equivalent degree) in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 15+ years of relevant employment experience - Typically requires 3 years of supervisory/management experience #LI-KM4 Pay Range: $200,000 - $300,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion – you’re always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Remote Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

We do Consulting Differently The Integrated Health Solutions (IHS) practice at Berkeley Research Group (BRG) provides end-to-end advisory support to healthcare providers, payers, investors, and other stakeholders navigating complex strategic, operational, financial, and clinical challenges. Led by seasoned healthcare executives, operators, and clinicians, IHS partners with organizations to drive sustainable performance improvement and long-term growth through strategic growth design, operating model transformation, AI and digital enablement, clinical quality and patient care optimization, and revenue strategy—helping clients build resilient, future-ready healthcare enterprises in an increasingly complex environment. Our four core service offerings include:  - Business Transformation Advisory - Margin & Operational Improvement - Clinical & Quality Transformation - AI & Digital Solutions Business Transformation Advisory partners with healthcare organizations to define enterprise-wide strategy and align financial, clinical, and operational priorities to long-term objectives. This work spans enterprise and service line strategy, population health and value-based care models, long-range financial forecasting, and regulatory and alternative payment methodologies—helping leaders make informed decisions that drive sustainable growth, resilience, and system-wide performance improvement. The Associate Director will play a critical leadership role in shaping and delivering strategic engagements for healthcare clients, including health systems, payers, and emerging healthcare platforms. This role blends client leadership, problem solving, and business development, with a strong focus on translating strategy into actionable, measurable outcomes. Willing to travel consistently (50%), depending on project requirements and client expectations, is required for this position. Responsibilities Client Leadership & Delivery - Lead day-to-day execution of complex strategic engagements (e.g., enterprise strategy, service line planning, M&A strategy, growth initiatives) - Serve as a primary client contact, building trusted relationships with executive stakeholders (C-suite, service line leaders, board members) - Translate ambiguous client challenges into structured problem statements, hypotheses, and actionable workplans - Ensure delivery of high-quality, data-driven insights with clear executive-level storytelling - Oversee development of financial models, market analyses, and strategic recommendations Strategic Problem Solving - Lead market assessments, competitive benchmarking, and growth opportunity identification - Drive service line strategy development (e.g., orthopedics, cardiovascular, oncology) - Support development of partnerships and affiliations - Integrate operational, financial, and clinical considerations into strategic recommendations - Incorporate AI, data, and digital capabilities into strategic solutions Team Leadership & Development - Manage and mentor junior team members (Senior Associates, Associates) - Provide guidance on analytical approach, deliverable quality, and client communication - Support team staffing, utilization, and performance feedback processes - Foster a collaborative, high-performance team environment Business Development & Practice Growth - Support proposal development, RFP responses, and pitch materials - Identify expansion opportunities within existing client relationships - Contribute to thought leadership (whitepapers, insights, market perspectives) - Participate in building repeatable methodologies, tools, and IP Qualifications - Bachelor’s degree required; MBA, MHA, MPH, or equivalent advanced degree preferred6–10+ years of experience in healthcare consulting, strategy, or health system operations - Experience leading strategic engagements (e.g., growth strategy, service line planning, transformation) - Demonstrated experience working with executive stakeholders - Strong strategic thinking and structured problem-solving capabilities - Experience with financial modeling, market sizing, and ROI analysis - Deep understanding of healthcare industry dynamics (providers, payers, regulatory environment) - Familiarity with data analytics, digital health, and/or AI-enabled solutions preferred - Proven ability to lead teams and manage multiple workstreams - Strong executive communication and presentation skills - Ability to influence decision-making at senior levels - High level of ownership, accountability, and professionalism Salary Range: $150,000 – $250,000 per year Job title and compensation to be determined based on qualifications and experience.   Candidate must be able to submit verification of his/her legal right to work in the U.S., without company sponsorship. About BRG BRG combines world-leading academic credentials with world-tested business expertise and purpose-built emerging technologies. Our culture centers on agility and connectivity which sets us apart and gets you ahead. At BRG, our professionals include specialist consultants, industry experts, renowned academics, and leading-edge data scientists. Together, they bring a diversity of real-world experience, data, and human and artificial intelligence, to economics, disputes, and investigations; corporate finance; and performance improvement services that address the most complex challenges facing organizations across the globe. Our unique structure nurtures the interdisciplinary relationships that give us the edge, laying the groundwork for more informed insights and more original, incisive thinking. When paired with our global reach and resources, our diverse perspectives and technical capabilities make us uniquely capable to address our clients’ challenges. We get results because we know how to apply our thinking to your world. At BRG, we don’t just show you what’s possible. We’re built to help you make it happen. BRG is proud to be an Equal Opportunity Employer. Our hiring practices provide equal opportunity for employment without regard to race, religion, color, sex, gender, national origin, age, United States military veteran status, ancestry, sexual orientation, marital status, family structure, medical condition including genetic characteristics or information, veteran status, or mental or physical disability so long as the essential functions of the job can be performed with or without reasonable accommodation, or any other protected category under federal, state, or local law.