• Develop and execute a strategic sales plan, targeting U.S. federal agencies, focusing on increasing product adoption and customer retention. • Cultivate strong, lasting relationships with key decision-makers and stakeholders within federal agencies. • Identify customer needs and align them with our products to provide tailored protection solutions. • Conduct product presentations, demonstrations, and training sessions to federal agency personnel and procurement teams. • Collaborate with internal teams (R&D, Marketing, and Product Management) to communicate market feedback and ensure products meet client requirements. • Manage the entire sales cycle, from prospecting and lead generation to closing deals and account management. • Stay up to date with industry trends, federal procurement guidelines, and competitor products. • Prepare and submit accurate sales forecasts, activity reports, and market analysis to the VP Federal Sales.

Overview: At Alnylam Pharmaceuticals, we are leading the RNAi Revolution, developing innovative therapies that transform the lives of patients with rare and prevalent diseases. As a Federal Account Director, you will play a key role in executing our U.S. federal market access strategy, with a primary focus on assigned Department of Veterans Affairs (VA) VISN and VA Hospital accounts, as well as supporting Department of Defense (DoD) ecosystems where applicable. This position requires expertise in the federal healthcare landscape, including VA/DoD reimbursement dynamics, formulary processes, Criteria for Use (CFU), utilization management, and stakeholder engagement, particularly for therapies requiring administration by healthcare professionals under the medical benefit. You will focus on optimizing access and appropriate utilization of Alnylam's HCP-administered products by ensuring compliant application of the VA National Formulary and CFU at your assigned accounts. In collaboration with cross-functional partners, you will educate site administrators, department chairs, and clinical influencers on the value proposition of Alnylam products for Veterans and service members. You will also support cross-functional pull-through efforts, contribute to federal access strategies, and provide insights to inform broader team initiatives. This role demands agility to navigate evolving policies, market conditions, and federal requirements while identifying opportunities to enhance product utilization. You will collaborate with internal teams, including sales, medical affairs, health economics, and strategic accounts, to align with Alnylam's commercial objectives and mission to deliver groundbreaking RNAi therapeutics to patients in federal systems. This is a field-based remote position requiring up to 50-70% travel and reports to the Senior Director, Federal Accounts. Key Responsibilities: - Execute federal access strategies within assigned VISN and VA Hospital accounts to optimize patient access and appropriate utilization of Alnylam's portfolio. - Ensure compliant application of the VA National Formulary and Criteria for Use (CFU) for Alnylam products at the site level. - Partner with the cross-functional team to ensure that critical education is delivered to key stakeholders including site administrators, department chairs, and healthcare professionals. This education includes: disease-state education, clinical information, as well as administration requirements of Alnylam’s therapies. - Analyze account-specific data, trends, and utilization metrics to identify opportunities for enhanced pull-through and appropriate use. - Collaborate with field sales, Regional Business Directors, and cross-functional partners to implement pull-through tactics and support sales performance in federal accounts. - Contribute to the development and execution of account plans, sharing insights and best practices with the federal team. - Support federal market development initiatives, including engagement with organizations such as the Association of Military Surgeons of the United States (AMSUS). - Provide federal payer and account insights to market access, HEOR, patient services, and leadership teams to inform strategies and address gaps. Accountabilities: - Build and maintain multi-level relationships within assigned federal accounts (VISNs, VA Hospitals, and related DoD entities), positioning Alnylam as a trusted partner for HCP-administered innovations benefiting Veterans and service members. - Navigate federal provider structures to engage key decision-makers, influencers, and clinical stakeholders, fostering long-term partnerships that support Alnylam's current products and pipeline. - Prioritize account activities to ensure consistent, compliant implementation of national formulary and CFU, addressing site-specific needs for medical benefit therapies. - Collaborate with internal experts (e.g., Medical Affairs, national contracting, and policy teams) to support access positioning and medical policy alignment. - Deliver tailored education on the value proposition of Alnylam products, emphasizing benefits for patient populations served in federal settings. - Review sales, utilization, and trend data to uncover pull-through opportunities, developing tactics aligned with team KPIs. - Work with field sales teams to execute pull-through plans, providing training on federal payer dynamics, formulary processes, CFU requirements, and reimbursement for HCP-administered therapies. - Maintain compliance with all legal, regulatory, and company policies in stakeholder interactions and program execution. - Contribute to team knowledge sharing by documenting best practices, participating in training, and supporting pilot programs or initiatives. Qualifications: - Bachelor's degree required (business or science preferred); advanced degree (e.g., MBA, PharmD) a plus. - Minimum 7+ years of pharmaceutical/biotech experience, with at least 3 years in account management, payer access, or related roles; direct experience in VA/DoD or federal channels preferred. - Proven track record in managing complex accounts, influencing stakeholders, and driving results in healthcare environments. - In-depth knowledge of federal healthcare systems, including VA National Formulary, Criteria for Use (CFU), VISN dynamics, aprocurement process for HCP-administered therapies, medical benefit coverage, utilization management, site-of-care strategies, and reimbursement pathways. - Strong analytical skills to interpret data, identify opportunities, and develop actionable account plans. - Consultative approach to stakeholder engagement, with expertise in value communication and educational program delivery. - Understanding of payer economics, utilization management, and evolving U.S. policies impacting federal systems. - Comprehensive knowledge of pharmaceutical operations, including prescribing, regulations, supply chain, managed care, sales, and compliance. - Excellent communication, presentation, and relationship-building skills; ability to collaborate effectively in cross-functional teams. #LI-ST1 #LI-Remote U.S. Pay Range $211,500.00 - $286,100.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

• Lead client accounts in excess of £400K revenue • Provide strategic direction for campaigns and projects • Manage client relationships and satisfaction • Ensure quality deliverables within timelines and budgets • Facilitate client meetings and drive annual strategy • Identify new business opportunities and drive organic growth

• Reporting to the Sr Regional Director of Sales • Responsible for aggressively building a pipeline, delivering revenue, and expanding the Cofense market share • Identify, build and test Champions/key decision-makers in Information Technology & Security departments • Prospecting, conducting creative and thoughtful discovery, technical presentation, pipeline management and a demonstrated ability to close • Accurately and consistently qualify sales forecasts and opportunity funnels using MEDDPICC • Drive the full sales cycle from lead generation, solution demos, negotiations, and closing deals with new customers • Represent the company at events as required