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Parabilis Medicines logo
Parabilis Medicines

Advancing ultra-tunable Helicon peptide therapeutics to achieve extraordinary outcomes for people affected by cancer.

Senior Director, Clinical Pharmacology, Pharmacometrics

DirectorDirectorOtherRemoteSeniorTeam 51-200Since 2016H1B No SponsorCompany SiteLinkedIn

Location

Massachusetts

Posted

158 days ago

Salary

$250K - $300K / year

Seniority

Senior

Postgraduate Degree12 yrs expEnglish

Job Description

Senior Director, Clinical Pharmacology, Pharmacometrics

Parabilis Medicines

• Provide scientific, functional, and operational leadership across assigned drug development programs. • Design and execute program-level clinical pharmacology and pharmacometric strategies. • Ensure integration into global development plans. • Work cross-functionally with Clinical Development, DMPK, Regulatory, and Biostatistics to optimize dose selection. • Oversee planning, conduct, and interpretation of clinical pharmacology studies. • Author and review clinical pharmacology sections of regulatory submissions.

Job Requirements

  • PhD, PharmD, MD, or equivalent in Clinical Pharmacology, Pharmaceutical Sciences, or a related quantitative discipline.
  • 12+ years of experience in clinical pharmacology, pharmacometrics, or quantitative drug development in the biopharmaceutical industry.
  • Demonstrated success in designing and leading clinical pharmacology strategies at the program or portfolio level.
  • Strong understanding of regulatory expectations (FDA, EMA, PMDA, NMPA) for clinical pharmacology and modeling & simulation.
  • Proficiency in modeling and data analysis tools (e.g., NONMEM, Monolix, Phoenix NLME, MATLAB, R).
  • Proven ability to lead in matrixed environments, influence cross-functional teams, and drive decision-making.
  • Experience with both small molecules and biologics; exposure to novel modalities (e.g., gene or cell therapies) preferred.
  • Excellent communication, collaboration, and presentation skills.
  • Demonstrated use of AI tools in your current role and responsibilities is required. Advanced or innovated use of AI is a strong plus.

Benefits

  • Parabilis’s total compensation package includes an annual target bonus
  • equity
  • a comprehensive suite of competitive benefits designed to support our employees’ overall well-being

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