• Maintain all Linux-based servers and clients located on premises and in an AWS cloud environment. • Follow system administration best practices. • Patch and configure systems in compliance with NOAA security requirements. • Upgrade operating systems in advance of end-of-support dates. • Support software development efforts. • Deploy software application updates for both COTS as well as internal applications. • Plan and implement migration of local systems to a cloud environment, where possible, in a cost-effective manner. • Ensure reliable system and data backups. • Manage/maintain server certificates. • Maintain Red Hat Enterprise Linux subscriptions. • Perform ongoing performance tuning, hardware upgrades, and resource optimization as required. • Participate in a rotation to provide 24x7x365 on-call support for the primary IT mission essential data processing, applications, and functions to support the continuity of operations of the NDBC information system. • Support IT architecture improvements to ensure continuity of operations for primary mission essential functions and the flow of data. • Support the annual NDBC IT Assessment and Authorization (A&A) audits through security patching and security-minded configuration updates; actively address changes needed as a result of Plan of Action & Milestones (POAM) requirements; help ensure NDBC maintains its Authority to Operate (ATO). • Communicate/brief upcoming maintenance efforts and/or anticipated impacts to stakeholders. • Implement strategies to automate routine administration tasks. • Maintain and monitor data center environmental equipment.

• Own and lead CG Oncology’s clinical, quality, and regulatory enterprise systems (eTMF, CTMS, EDC, IRT, QMS, Veeva QualityDocs & Training, RIM Vault) • Ensure systems are inspection-ready, compliant, and adopted across global Phase I–III trials • Act as the business owner for systems strategy, validation oversight, continuous improvement, and user enablement • Partner with CROs and vendors to ensure data quality, timelines, and budget discipline • Play a visible role in regulatory inspections, audits, and submissions • Help shape how systems scale as CG Oncology grows its pipeline

• Own day-to-day administration and optimization of core GTM systems (e.g., Salesforce, marketing automation, customer success platforms, revenue/billing tools) • Own system configuration, change management, and release processes to ensure reliability and minimize business disruption • Establish and enforce data governance, system standards, and best practices across GTM tools • Support the definition and maintenance of key GTM metrics, fields, and data models • Analyze existing GTM processes to identify opportunities for automation, standardization, and efficiency • Balance flexibility for the business with the need for system discipline and long-term scalability • Act as a trusted partner for leaders by translating business strategy into system architecture and workflows

• Administer and maintain Active Directory (AD), including: • User and group management • Organizational Units (OUs) • Group Policies (GPOs) • Access rights and permissions • Manage user access and permissions across systems, applications, and network resources following the principle of least privilege • Create, modify, and deactivate user accounts; manage onboarding and offboarding processes • Administer Google Workspace (Google Admin Console): • User and group management • Security settings and access controls • Email, Drive, and application permissions • Implement and enforce password policies and security controls, including: • Password complexity and rotation policies • Multi-Factor Authentication (MFA) • Account lockout policies • Monitor system access and security logs; identify and respond to potential security risks • Ensure compliance with internal security standards and IT best practices • Troubleshoot access, authentication, and permission-related issues • Collaborate with IT and security teams to improve infrastructure security and reliability