PSI CRO AG

• Participate in the identification of opportunities for AI-driven automation and process optimization • Architecture, develop, and implement AI/ML solutions for Clinical Data Management and operational processes using LLMs, RAG, traditional ML techniques, and rule-based approaches • Define and execute strategies for model development, testing, validation, benchmarking, and training data preparation • Integrate AI solutions into existing desktop and web-based software platforms (primarily C#/.NET applications) • Collaborate with cross-functional stakeholders to ensure alignment with regulatory, quality, and operational requirements • Prepare and maintain technical documentation related to software applications, AI models, and development processes • Stay current with advancements in AI, machine learning, and software engineering technologies, and proactively evaluate their applicability within the organization

• Write short-form and long-form content on PSI's clinical trial services (blogs, white papers, case studies) • Revise and edit content before publication • Work with Digital Marketing Strategists to monitor content performance and engagement • Conduct research on assigned topics and identify third-party sources to ensure PSI content is authoritative and accurate • Work with the Marketing Strategist and Global Marketing Manager to build editorial calendars • Conduct interviews with internal & external SME's to identify topics of interest and opportunities to showcase PSI expertise • Collaborate with team members to ensure consistency in branding, style and messaging and alignment with the PSI Style Guide

• Represents the department and serves as the liaison between Systems Development, Process Improvement, and business end-users from all functional areas • Determines operational objectives within the department • Reviews, analyses, and proposes modifications to business systems to support departmental business needs • Communicates departmental business technology priorities to Systems Development and Process Improvement • Manages internal department business technology projects • Writes and maintains user documentation, provides training to end-users • Provides support and communicates potential business impact to end-users from all functional areas, acting as an escalation point and subject matter expert for departmental business technology systems • Participates in department initiatives related to new and existing business applications

• Contribute to global marketing strategy • Plan and execute multi-channel marketing campaigns to generate qualified leads • Helps develop the strategic plan for social media channels and digital events • Managing day-to-day tactics and overall campaign management in alignment with overall marketing goals and business objectives • Plan, organize, and execute webinars and digital events, ensuring a seamless experience for participants and stakeholders • Managing vendors where appropriate • Helps develop PSI marketing strategy in support of sales and marketing • Monitors and analyzes marketing campaign performance and adjusts strategies, track marketing KPIs and evaluates ROI • Manage and maintain PR contacts in industry/paid advertisements/placements • Conduct market research • Manages marketing team activities across social channels and digital events

Title: Proposal Manager Location: Mississauga, ON, Canada remote Full-time Job Description: Company Description We are the company that cares – for our staff, for our clients, for our partners and for the quality of work we do. A dynamic, global company founded in 1995, we bring together more than 3,200 driven, dedicated and passionate individuals. We work on the frontline of medical science, changing lives, and bringing new medicines to those who need them. Compensation: CAD 90,000 - CAD 120,000 - yearly At PSI, Proposal Manager coordinates all phases of PSI’s proposal process while maintaining the company’s win rate of 30% and higher. You will contribute to everything from RFP strategy to bid defense slide decks. You will partner with global teams of subject matter experts from Feasibility, Medical Affairs, Project Management, Clinical Operations, Budgeting, and Business Development to rapidly produce winning proposals. This position is home-based This full proposal development cycle will include: - Preparing viable RFP calendars and ensuring RFP milestones are met by all involved individuals in a timely manner - Organizing, attending, and leading strategy calls for each RFP; preparing and distributing minutes/action items - Developing draft budgets: reviewing clients’ specifications, obtaining quality feedback from various stakeholders within the company - Working with the budgeting team to develop competitive budgets and obtaining missing costs - Preparing vendor RFPs and obtaining vendor quotes - Writing strategic proposals that meet our clients’ needs - Providing support for bid defense meetings - Maintaining all RFPs in Salesforce and PSI’s CTMS Qualification: - A minimum of a four-year degree from an accredited college or University - Experience managing full-service clinical trial proposals at a CRO - Writing and editing skills - Analytical skills - Time management and organization skills - Ability to manage multiple assignments under deadlines - Proven track record of proposal win rates - Flexibility and creativity in responding to potential clients - Proficiency in Microsoft Word, Excel and PowerPoint Additional Information This is a creative tight-knit team of professionals motivated by producing quality proposals that resonate with our customers. Our culture is open, collaborative, and purposeful. We’re now looking for talented people who don’t believe in one-size-fits-all templates and have a passion for writing proposals that get read and remembered.

• Coordinates all phases of PSI’s proposal process while maintaining the company’s win rate of 30% and higher. • Contributes to everything from RFP strategy to bid defense slide decks. • Partners with global teams of subject matter experts from various departments to produce winning proposals. • Prepares viable RFP calendars and ensures RFP milestones are met. • Organizes, attends, and leads strategy calls for each RFP; prepares and distributes minutes/action items. • Develops draft budgets by reviewing clients’ specifications. • Works with the budgeting team to develop competitive budgets and obtain missing costs. • Prepares vendor RFPs and obtains vendor quotes. • Writes strategic proposals that meet clients’ needs. • Provides support for bid defense meetings. • Maintains all RFPs in Salesforce and PSI’s CTMS.

Role Description As a Full stack Developer, you will be involved in development of projects for internal clients and will provide quality coding to support PSI business processes and operations with the focus on AI solutions. Full-time employment based in Lithuania. - Architect, develop and maintain business applications - Process user requests for developing of new and support for existing IT systems - Prepare documentation related to development and maintenance of business applications - Execute and implement software tests, participate in code reviews - Follow the development standards applied within the department - Track the development, maintenance and related tasks in the tracking system used within the team - Follow the progress of systems development technologies and advance professional skills as necessary Qualifications - BSc/BA in computer science, software engineering or relevant discipline - Full working proficiency in English - Knowledge of web technologies including JS(ES+) - Knowledge of C# language, Microsoft .NET frameworks, technologies and best practices - Knowledge of Transact SQL, MS SQL functions, stored procedures and other SQL objects Requirements - Experience with Machine Learning, Deep Learning, Neural Networks (CNNs, RNNs, Transformers), Natural Language Processing (NLP), Computer Vision (Good to have) - Python development experience (Good to have) - Experience with Blazor (Good to have) Benefits - Stable, privately-owned company, organically growing since 1995 - Opportunity to work remotely in Lithuania - Intensive induction program, technical and industry-related trainings for an optimal start and continuous development - Diverse projects that include but are not limited to web and desktop apps, ERP system, BPM system, document management system, AI initiatives and more - Friendly and supportive atmosphere in a committed team - International environment, with colleagues around the world - Opportunities to quickly see the results of your work - Gross salary range for Middle Developer: 3200-5000 EUR monthly (based on your overall experience and qualifications) - Corporate benefits: performance-based bonus, supplementary health insurance, annual team events

• Implement, manage and improve our compensation and benefits programs • Oversee the day-to-day analysis, execution, and communication of global pay and benefits. • Define a fair, equitable and competitive total compensation and benefits package that fits and is aligned with our company's strategy, business goals and talent needs. • Develop a consistent compensation philosophy in line with work culture and organizational objectives. • Utilize various methods and techniques to make data-based decisions on direct financial, indirect financial and nonfinancial compensation plans. • Support the Training & Resourcing team with recruitment and talent management activities. • Support the Finance team with budgets, year-end bonus incentive payment process and financial analysis of all compensation and benefit plans. • Support Legal team to ensure compliance of compensation and benefit programs with applicable laws and regulations. • Participate in salary and labor market surveys to determine prevailing pay rates and benefits. • Conduct ongoing research and report on emerging trends, issues and best practices. • Assess competitors' compensation and benefits plans and make recommendations for enhancements to our existing plans. • Provide subject matter expertise and internal support to key stakeholders including department heads, local country management, legal, finance and training & resourcing teams on a variety of compensation and benefit issues.

Title: Medical Monitor (Canada Board-Certified Gastroenterologist) Location: Remote, REMOTE, Canada Job Description: Full-time Company Description PSI is a leading Contract Research Organization with more than 30 years in the industry, offering a perfect balance between stability and innovation to both clients and employees. We focus on delivering quality and on-time services across a variety of therapeutic indications. Job Description PSI Medical Monitors provide medical input to global clinical studies and advise the teams and business partners, while always focusing on patients' safety and well-being. Home-Based in Canada Responsibilities: - Acts as the primary point of contact for all parties on all trial-specific medical and safety-related questions - Provides input for responses to regulatory authorities and Institutional Review Boards (IRBs)/Independent Ethics Committees (IECs) on trial-specific medical and safety-related questions - Monitors trial participant safety - Participates in trial participant recruitment boost and retention activities - Presents on medical matters at kick-off and investigator meetings - Trains trial team in the therapeutic area and medical aspects of the protocol - Develops and reviews trial-specific documents within the scope of medical monitoring - Manages ongoing trial risks related to medical monitoring - Performs ongoing medical review of the operational clinical trial database; provides support to Medical Reviewer(s) assigned to the trial - Reviews protocol deviations - Reviews RAE reports, writes and/or reviews SAE narratives, supports Pharmacovigilance team with outstanding safety queries, interacts with sponsor on site safety issues - Reviews IND/SUSAR Safety Reports, updates/amendments to essential trial records, and annual IND reports with sponsor data (per sponsor request) - Participates in management of trial-related committees (e.g., independent data monitoring committee (IDMC)/adjudication committees) as described in the corresponding trial-specific charter(s) - Supports Pharmacovigilance, Medical Data Review and Data Management with reconciliation of safety and operational clinical trial databases - Reviews clinical study reports (CSRs), including safety narratives and tables, figures, and listings (TFLs) - Provides medical expertise on an as-needed basis in trials where medical monitoring is not a contract deliverable - Prepares for and participates in trial audits, follows up on audit findings - Participates in feasibility assessment of potential and ongoing trials in the country/region - Participates in bid defense meetings and other interactions with clients - Acts as a medical expert and provides therapeutic expertise to other PSI departments Qualifications - Medical Doctor degree required - Canada Board Certification in Gastroenterology required - Experience as a practicing Gastroenterology (minimum of 10 years) - Clinical Research experience preferred - Proficiency with MS Office applications - Communication, presentation and analytical skills - Problem-solving, team and detail-oriented Additional Information As part of PSI's Medical Monitoring team, you will join our international group of medical professionals, build a career on the frontline of medical science and use your knowledge and expertise to help bring new medications to patients that need them.

Role Description PSI Medical Monitors provide medical input to global clinical studies and advise the teams and business partners, while always focusing on patients' safety and well-being. Home-Based in the United States. Responsibilities: - Acts as the primary point of contact for all parties on all trial-specific medical and safety-related questions. - Provides input for responses to regulatory authorities and Institutional Review Boards (IRBs)/Independent Ethics Committees (IECs) on trial-specific medical and safety-related questions. - Monitors trial participant safety. - Participates in trial participant recruitment boost and retention activities. - Presents on medical matters at kick-off and investigator meetings. - Trains trial team in the therapeutic area and medical aspects of the protocol. - Develops and reviews trial-specific documents within the scope of medical monitoring. - Manages ongoing trial risks related to medical monitoring. - Performs ongoing medical review of the operational clinical trial database; provides support to Medical Reviewer(s) assigned to the trial. - Reviews protocol deviations. - Reviews RAE reports, writes and/or reviews SAE narratives, supports Pharmacovigilance team with outstanding safety queries, interacts with sponsor on site safety issues. - Reviews IND/SUSAR Safety Reports, updates/amendments to essential trial records, and annual IND reports with sponsor data (per sponsor request). - Participates in management of trial-related committees (e.g., independent data monitoring committee (IDMC)/adjudication committees) as described in the corresponding trial-specific charter(s). - Supports Pharmacovigilance, Medical Data Review and Data Management with reconciliation of safety and operational clinical trial databases. - Reviews clinical study reports (CSRs), including safety narratives and tables, figures, and listings (TFLs). - Provides medical expertise on an as-needed basis in trials where medical monitoring is not a contract deliverable. - Prepares for and participates in trial audits, follows up on audit findings. - Participates in feasibility assessment of potential and ongoing trials in the country/region. - Participates in bid defense meetings and other interactions with clients. - Acts as a medical expert and provides therapeutic expertise to other PSI departments. Qualifications - Medical Doctor degree required. - US Board Certification in Gastroenterology required. - Experience as a practicing Gastroenterologist (minimum of 10 years). - Clinical Research experience preferred. - Proficiency with MS Office applications. - Communication, presentation and analytical skills. - Problem-solving, team and detail-oriented. Benefits - As part of PSI's Medical Monitoring team, you will join our international group of medical professionals. - Build a career on the frontline of medical science. - Use your knowledge and expertise to help bring new medications to patients that need them.