Nuvation Bio

Role Description Nuvation Bio is looking for a highly motivated and productive Principal Scientist to join our Research Department supporting our drug discovery and development programs. The Principal Scientist will contribute to research for multiple oncology discovery programs. They will initiate, direct, and manage external and internal experimental studies that are critical to advancement of programs, informing corporate strategy, and working to serve the unmet medical needs in oncology. You will be responsible for: - Support the research strategy for multiple oncology programs by designing and executing critical and relevant experimental studies that further the understanding of Nuvation Bio compounds. - Responsible for study planning, protocol design, study execution, and data analysis of pharmacology and mechanism of action studies. - Manage outsourced studies with external vendors/CROs/academic collaborators. - Support medicinal chemists by providing data critical to understand SAR/biochemical characterization of early-stage programs. - Work cross-functionally with members of the broader research team and effectively collaborate with a fully integrated team to facilitate the success of Nuvation projects. - Build our reputation in the scientific community with conference presentations and publications. - All other duties as assigned. Qualifications - PhD in relevant biological discipline with a minimum of 5+ years’ experience preferred, or MS with 7+ years, Bachelor’s degree with 10+ years of relevant pharmaceutical industry experience in a fast-paced environment. - Demonstrated and broad expertise in cancer cell biology with knowledge of relevant experimental techniques, including in vitro and in vivo oncology model systems. - Demonstrated expertise in the evaluation and development of small molecules. - Strong track record in oncology demonstrating knowledge of multiple fields of biology, reflected in multiple successful projects and publications. - Exceptional problem solving, analytical thinking, and strategic skills. - Excellent written and verbal communication skills with the proven ability to work effectively as a member of a multidisciplinary team. Requirements - Problem-Solver: As an action-oriented self-starter, you’re eager to apply your expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges. - Personable: You establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives. - Credible: Thorough understanding of clinical methodologies and providing sound analytical support, you quickly establish credibility as a reliable resource. - Emotional intelligence, curiosity, and a knack to figure out a way to build something better. - Communication: Effectively listens, conveys, and receives ideas. Maintains a consistent flow of information. A strong presenter and effective communicator with the ability to influence stakeholders. - Accountability: Acts with a clear sense of ownership - whether the task is in their role description. Holds yourself and others accountable to execute all tasks at hand through seen and unforeseen circumstances with high quality and integrity. - Adaptability: Can manage in an environment of ambiguity. Embraces the change of a new system, process, technology, or idea in the organization. You could reassess priorities, alter goals and take risks. Benefits - Competitive Base Salary, Bonus, and Equity Plans. - Unlimited Vacation and 10 Sick Days Annually. - Excellent Medical, Dental, and Vision Coverage. - 401K with Company Matching. - And much more!

Role Description As a key member of Nuvation Bio’s commercial sales team, the Oncology Account Manager will act as the primary point of commercial contact within an assigned territory and customer base, working collaboratively with cross-functional field-based partners to consistently achieve and surpass sales targets within a designated geographic area. The ideal candidate will possess expert knowledge of oncology market dynamics; specifically, NSCLC, including key customers and accounts, and a passion for delivering impactful therapies and transforming the lives of appropriate patients. The chosen candidate will also be directly responsible for creating and executing strategic cross-functional account plans within the assigned territory. This role reports to the Regional Business Director and will be based in or near a major city within the assigned territory. Responsibilities - Act as the primary point of commercial contact to establish meaningful relationships with key stakeholders and healthcare professionals within the assigned territory. - Responsible for demand generation efforts and drive awareness by actively promoting Nuvation Bio and appropriate use of Nuvation Bio’s products to healthcare professionals in assigned geography. - Leverage intel and insights to develop account business plans, resulting in increased engagement with customers and achievement of sales goals at launch and beyond while ensuring customer expectations are exceeded. - Understand and lead local market analysis, gather insights in partnership with cross-functional partners to help identify opportunities. - Leverage new technologies (i.e., Omnichannel) to build strategies and tactics to the aligned opportunity and execute on the brand strategy. - Comprehensive understanding of Nuvation Bio competitor landscape in the NSCLC disease state as well as a general understanding of the reimbursement environment, and oral oncolytic distribution to enhance strategic business plans. - Conduct presentations and convey complex scientific information fluently to customers in a professional, compliant, and ethical manner. - Partner with the data and analytics team to maximize the use of data and reports that enable precision customer targeting and the highest level of customer service. - Demonstrate initiative and willingness to work hands-on with a sense of urgency, in a fast-paced entrepreneurial environment. - Identify and represent Nuvation Bio at local, regional, and national medical conferences, symposiums, and conventions. - Compliantly partner with marketing, market access, and medical to develop a well-defined strategy to support the need of each customer. - Perform all administrative functions required for the position, including reporting appropriate call activity, expense report submission, and strictly adhering to relevant regulatory, compliance guidelines, and company policies. Qualifications - Bachelor’s degree in business, Biological Sciences, or related discipline. - Minimum of 7+ years of account sales experience in the pharmaceutical/biotechnology industry, with 5+ years of relevant oncology experience (solid tumors and/or oral-oncolytic) preferred. - Proven and consistent track record of meeting/exceeding sales goals and objectives, preferably in small/rare competitive markets. - Direct experience working with key opinion leaders and/or executive-level customers of high influence in large practices, hospitals, and community networks in assigned territory. - Demonstrated success launching new products working in small to mid-size biotech companies, reflecting an entrepreneurial culture and innovative mindset. - Outstanding interpersonal, selling, presentation, and negotiation skills: focused on assisting customers in finding solutions to their needs and/or resolving issues. - Strong technical proficiency with experience promoting product(s) in a virtual environment using digital tools, systems, and technology. - Significant overnight travel may be required (up to 65% overnight travel), including travel for company meetings, conferences/exhibits. - Ability to travel by car, plane, or train is required. - Must live within the assigned geography. - An essential requirement of the position is to meet credentialing requirements for access to academic institutions, medical facilities, and organizations that are in the assigned territory. Behavioral Skills - Problem-Solver: Eager to apply expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges. - Personable: Establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives. - Credible: Establish credibility as a reliable resource through a thorough understanding of clinical methodologies and providing sound analytical support. - Emotional Intelligence: Curiosity and a knack to figure out a way to build something better. - Communication: Effectively listens, conveys, and receives ideas. A strong presenter and effective communicator with the ability to influence stakeholders. - Accountability: Acts with a clear sense of ownership and holds yourself and others accountable to execute all tasks at hand with high quality and integrity. - Adaptability: Can manage in an environment of ambiguity and embraces change in systems, processes, technology, or ideas. Benefits - Competitive Base Salary, Bonus, and Equity Plans - Unlimited Vacation and 10 Sick Days Annually - Excellent Medical, Dental, and Vision Coverage - 401K with Company Matching - And much more!

Role Description The Pharmacovigilance Physician will report to the VP of Pharmacovigilance. The PV/Drug Safety physician will be a medical professional responsible for ensuring drug safety throughout a product's lifecycle by detecting, assessing, and managing adverse events. They will conduct medical reviews of safety reports (ICSRs), identify risks, and ensure compliance with global regulations. You will be responsible for: - Providing clinical and scientific leadership within the pharmacovigilance function. - Engaging cross-functional internal workstreams including therapeutic area development, biostatistics, clinical operations, and regulatory affairs. - Providing clinical input to the design of clinical trials, signal detection and management activities, post-authorization studies, risk minimization, and risk communication. - Performing case series analysis of adverse events and review of passive surveillance data mining signals of disproportionate reporting as well as safety issues from other sources. - Leading clinical safety and benefit-risk sections of regulatory documents and preparation for meetings with regulatory and public health authorities as well as advisory committees. - Performing post-marketing surveillance and regulatory reporting, as needed. - Guiding the operations of contract research organizations. - Serving as an exemplary leader, mentor, and trainer. Qualifications - MD, D.O. or non-US equivalent required. - Residency training & board certification highly preferred. - Clinical practice experience highly preferred. - Experience working with public health agencies highly preferred. - 2-4 years of prior experience in pharmacovigilance in an industry setting, either in a comparable role, or in clinical development. Requirements - Proven ability to collaborate effectively within dynamic and fast-moving technical teams to deliver high-quality results within established timelines. - Utilize technology supporting pharmacovigilance (e.g. for signal detection and regulatory reporting). - Interpret and integrate concepts and guidelines from FDA, EMA, PMDA and other regulatory agencies, government research organizations (e.g. NIH), public health agencies and nongovernmental organizations, and clinical practice groups. - Investigate new safety issues. - Communicate medical product benefits and risks to regulatory and public health authorities as well as the public. - Ability to thrive in a fast-paced environment while providing appropriate attention to detail. - Excellent analytical, problem-solving, strategic planning, and interpersonal skills. Behavioral skills to be successful... - Problem-Solver: As an action-oriented self-starter, you’re eager to apply your expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges. - Personable: You establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives. - Credible: With a thorough understanding of clinical methodologies and providing sound analytical support, you quickly establish credibility as a reliable resource. - Emotional intelligence: Curiosity, and a knack to figure out a way to build something better. - Communication: Effectively listens, conveys, and receives ideas. Maintains a consistent flow of information. A strong presenter and effective communicator with the ability to influence stakeholders. - Accountability: Acts with a clear sense of ownership - whether the task is in their role description. Holds yourself and others accountable to execute all tasks at hand through seen and unforeseen circumstances with high quality and integrity. - Adaptability: Can manage in an environment of ambiguity. Embraces the change of a new system, process, technology, or idea in the organization. You could reassess priorities, alter goals and take risks. Benefits - Competitive Base Salary, Bonus, and Equity Plans. - Unlimited Vacation and 10 Sick Days Annually. - Excellent Medical, Dental, and Vision Coverage. - 401K with Company Matching. - And much more!

Regional Medical Director Medical Affairs | Remote - Any State US | Full Time | From $235,000 to $265,000 per year Job Description What you’ll be doing The Regional Medical Director will perform a key role within Medical Affairs, supporting the oncology portfolio, including taletrectinib and safusidenib, through strategic alignment and execution of activities related to investigator/KOL engagement, insight collection, support of investigator and company sponsored trials, medical communications, and cross-functional collaboration. As part of the execution of Nuvation Bio Pharmaceuticals’ strategy, he/she, as a member of Medical Affairs, will work closely with the Clinical Development, Commercial, and Market Access functions. You will be responsible for… - Responsible for realization of medical/scientific objectives for the RMD team - Establish & maintain professional relationships with external experts, academic institutions, community networks, and managed care communities - Present critical medical and scientific information to external audiences and individuals (such as healthcare professionals, formulary committees, and medical meetings) - Identify unmet medical, educational, and research needs within the medical community, and make an intelligent interpretation of key relevant scientific data and translate this information to meet educational and research needs - Collaborate with cross‐functional teams in assessing education/research needs and develop education/research strategies to meet those needs - Provide medical and scientific support for internal collaborations, such as sales training, speaker bureau training, and other educational initiatives - Assist in the identification of investigators and sites for company sponsored trials - Participate in objective setting as well as contributing to the professional development for the RMD team - Serve as a liaison for the review, submission, execution, completion of ISR (Investigator Sponsored Research) proposals and facilitate the initiation of research projects - Represent Nuvation Bio at medical meetings, conferences, advisory boards, outreach meetings at key institutions and in interactions with thought leaders - Maintain knowledge of the lung and neuro oncology fields, stay current on leading edge medicines and development efforts, and provide expertise for business development opportunities as appropriate - Contribute to & be able to lead select Medical Affairs projects and execution through hybrid Home Office Medical responsibilities - Assure RMD team compliance with all corporate policies and regulatory guidelines What Knowledge & Experience you'll bring to us... - Advanced degree (MD, PhD, PharmD) in a medical or science-related specialty, although significant experience in the medical field may be considered in lieu of an advanced degree. - Requires at least 4 years of experience as field MSL/RMD with demonstrated excellent communication skills (oral and written) - A combination of education and experience may be considered - Strong and established relationships and experience in lung/thoracic oncology preferred - Solid understanding of drug development and life‐cycle development of a product required - Understanding of the FDA, Pharma Code and other ethical guidelines relevant to the pharmaceutical industry - Ability to cultivate and maintain relationships with clinical investigators and key opinion leaders in the relevant fields, and to establish trust through the consistent demonstration of scientific expertise and satisfactory follow‐through to requests from key opinion leaders - Able to articulate ideas and concepts, be persuasive and have the ability to convey complex, scientific ideas fluently to any audience - Must utilize effective, professional communications to cultivate and nurture strong working relationships with internal and external colleagues - Ability to conduct oneself in a highly professional and ethical manner - A thorough understanding of the clinical trial and investigator initiated study processes - Ability to multi‐task, work independently and focus on priorities - Must deal with ambiguity and thrive in an ever‐changing environment - Must live in assigned region - Travel minimum 50 % and manage a demanding schedule Behavioral skills to be successful... - Problem-Solver - As an action-oriented self-starter, you’re eager to apply your expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges. - Personable - You establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives. - Credible - Thorough understanding of clinical methodologies and providing sound analytical support, you quickly establish credibility as a reliable resource. - Emotional intelligence, curiosity, and a knack to figure out a way to build something better - Communication - Effectively listens, conveys, and receives ideas. Maintains a consistent flow of information. A strong presenter and effective communicator with the ability to influence stakeholders. - Accountability - Acts with a clear sense of ownership - whether the task is in their role description. Holds yourself and others accountable to execute all tasks at hand through seen and unforeseen circumstances with high quality and integrity. - Adaptability - Can manage in an environment of ambiguity. Embraces the change of a new system, process, technology, or idea in the organization. You could reassess priorities, alter goals and take risks. What we have for you! - Competitive Base Salary, Bonus, and Equity Plans - Unlimited Vacation and 10 Sick Days Annually - Excellent Medical, Dental, and Vision Coverage - 401K with Company Matching - and much more! The base pay offered will take into account internal equity and also may vary depending on the candidate’s job-related knowledge, skills, experience, and location among other factors. Our full-time regular positions also include an annual performance-based bonus and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, depending on the level and position offered.

Role Description As a key member of Nuvation Bio’s commercial sales team, the Oncology Account Manager will act as the primary point of commercial contact within an assigned territory and customer base, working collaboratively with cross-functional field-based partners to consistently achieve and surpass sales targets within a designated geographic area. The ideal candidate will possess expert knowledge of oncology market dynamics; specifically, NSCLC, including key customers and accounts, and a passion for delivering impactful therapies and transforming the lives of appropriate patients. The chosen candidate will also be directly responsible for creating and executing strategic cross-functional account plans within the assigned territory. This role reports to the Regional Business Director and will be based in or near a major city within the assigned territory. Responsibilities - Act as the primary point of commercial contact to establish meaningful relationships with key stakeholders and healthcare professionals within the assigned territory. - Responsible for demand generation efforts and drive awareness by actively promoting Nuvation Bio and appropriate use of Nuvation Bio’s products to healthcare professionals in assigned geography. - Leverage intel and insights to develop account business plans, resulting in increased engagement with customers and achievement of sales goals at launch and beyond while ensuring customer expectations are exceeded. - Understand and lead local market analysis, gather insights in partnership with cross-functional partners to help identify opportunities. - Leverage new technologies (i.e., Omnichannel) to build strategies and tactics aligned with opportunities and execute on the brand strategy. - Comprehensive understanding of Nuvation Bio competitor landscape in the NSCLC disease state as well as a general understanding of the reimbursement environment and oral oncolytic distribution to enhance strategic business plans. - Conduct presentations and convey complex scientific information fluently to customers in a professional, compliant, and ethical manner. - Partner with the data and analytics team to maximize the use of data and reports that enable precision customer targeting and the highest level of customer service. - Demonstrate initiative and willingness to work hands-on with a sense of urgency in a fast-paced entrepreneurial environment. - Identify and represent Nuvation Bio at local, regional, and national medical conferences, symposiums, and conventions. - Compliantly partner with marketing, market access, and medical to develop a well-defined strategy to support the needs of each customer. - Perform all administrative functions required for the position, including reporting appropriate call activity, expense report submission, and strictly adhering to relevant regulatory, compliance guidelines, and company policies. Qualifications - Bachelor’s degree in business, Biological Sciences, or related discipline. - Minimum of 7+ years of account sales experience in the pharmaceutical/biotechnology industry, with 5+ years of relevant oncology experience (solid tumors and/or oral-oncolytic) preferred. - Proven and consistent track record of meeting/exceeding sales goals and objectives, preferably in small/rare competitive markets. - Direct experience working with key opinion leaders and/or executive-level customers of high influence in large practices, hospitals, and community networks in assigned territory. - Demonstrated success launching new products working in small to mid-size biotech companies, reflecting an entrepreneurial culture and innovative mindset. - Outstanding interpersonal, selling, presentation, and negotiation skills focused on assisting customers in finding solutions to their needs and/or resolving issues. - Strong technical proficiency with experience promoting product(s) in a virtual environment using digital tools, systems, and technology. - Significant overnight travel may be required (up to 65% overnight travel), including travel for company meetings, conferences/exhibits. - Ability to travel by car, plane, or train is required. - Must live within the assigned geography. - An essential requirement of the position is to meet credentialing requirements for access to academic institutions, medical facilities, and organizations that are in the assigned territory. Behavioral Skills - Problem-Solver: As an action-oriented self-starter, eager to apply expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges. - Personable: Establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives. - Credible: Thorough understanding of clinical methodologies and providing sound analytical support, quickly establishing credibility as a reliable resource. - Emotional Intelligence: Curiosity and a knack to figure out a way to build something better. - Communication: Effectively listens, conveys, and receives ideas. Maintains a consistent flow of information. A strong presenter and effective communicator with the ability to influence stakeholders. - Accountability: Acts with a clear sense of ownership. Holds self and others accountable to execute all tasks at hand through seen and unforeseen circumstances with high quality and integrity. - Adaptability: Can manage in an environment of ambiguity. Embraces the change of a new system, process, technology, or idea in the organization. Benefits - Competitive Base Salary, Bonus, and Equity Plans - Unlimited Vacation and 10 Sick Days Annually - Excellent Medical, Dental, and Vision Coverage - 401K with Company Matching - And much more!

Role Description The Regional Marketing Manager will play a pivotal role in developing and executing marketing strategies to drive the continued success of the commercial launch of Taletrectinib, a ROS1 inhibitor. This individual will engage closely with key lung cancer thought leaders (TLs) and healthcare professionals (HCPs), ensuring alignment with brand commercial strategies while leading promotional initiatives that foster innovation and market penetration. Working in collaboration with cross-functional teams, the Regional Marketer will focus on building and maintaining strong relationships with TLs, serving as their primary point of contact for marketing efforts, and driving strategic initiatives at both national and regional levels. This Regional Marketer requires a deep understanding of oncology and an ability to gather insights, track performance, and adjust strategies to meet business objectives. The Regional Marketers will report to the VP Executive Director, Taletrectinib Marketing. This is a field-based role. Responsibilities - Develop commercial thought leader strategy and execution plan for company’s first product. - Create and manage a strategy for TL interactions specific to lung cancer, including building and maintaining US TL lists, tracking engagements, and ensuring consistent communication. - Develop and maintain relationships with TLs in lung cancer. Serve as their primary marketing contact, and work with other functions to support HCP engagement plans. - Identify and engage with promotional speakers to represent the brand in regional and national events. - Partner with other internal teams to implement commercial strategies and manage interactions with key accounts, ensuring alignment with business goals. - Develop proposals for national or local promotional projects that support innovation while meeting business objectives. Lead TL interface in these projects, including managing peer-to-peer programs and coordinating TL initiatives. - Lead insight collection from TLs through direct engagements, advisory boards, and national/regional events, providing actionable data to inform commercial strategy. - Lead peer-to-peer development plan and execution inclusive of vendor management, speaker identification and training, contracting and third-party coordination. - Develop success metrics to measure the effectiveness of the TL engagement strategy and adjust plans based on performance. Qualifications - Bachelor’s Degree in the field of computer science, information science, management information systems, business analytics, or business administration or equivalent experience. - 10+ years of experience in the pharmaceutical industry, with a proven track record in building relationships with TLs and influencing stakeholders. - Field-Based/Regional Marketing/ TLL experience required. - Oncology experience is required, with an emphasis on lung cancer. - Strong communication skills, both in one-on-one settings and larger group engagements. - Demonstrated success in building productive relationships with internal and external stakeholders, and an ability to influence cross-functional teams. - Proven ability to identify business needs, gather insights, and propose innovative strategies that align with business goals. - Ability to work in a fast-paced environment and manage workload independently. - Experience in sales, sales management, and marketing is an asset. - Experience in organizing advisory boards and conventions is a plus. - Team-focused mentality. - Ability to travel up to 65% of the time. Behavioral Skills - Problem-Solver: As an action-oriented self-starter, you’re eager to apply your expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges. - Personable: You establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives. - Credible: Thorough understanding of clinical methodologies and providing sound analytical support, you quickly establish credibility as a reliable resource. - Emotional Intelligence: Curiosity, and a knack to figure out a way to build something better. - Communication: Effectively listens, conveys, and receives ideas. Maintains a consistent flow of information. A strong presenter and effective communicator with the ability to influence stakeholders. - Accountability: Acts with a clear sense of ownership - whether the task is in their role description. Holds yourself and others accountable to execute all tasks at hand through seen and unforeseen circumstances with high quality and integrity. - Adaptability: Can manage in an environment of ambiguity. Embraces the change of a new system, process, technology, or idea in the organization. You could reassess priorities, alter goals and take risks. Benefits - Competitive Base Salary, Bonus, and Equity Plans. - Unlimited Vacation and 10 Sick Days Annually. - Excellent Medical, Dental, and Vision Coverage. - 401K with Company Matching. - And much more!

Role Description The Senior Director, Head of Field Medical will lead the Field Medical Affairs team and strategy. They will also be a strategic partner to the Clinical, Regulatory, and Commercial teams for all Nuvation clinical programs and products. - Core & integral member of Medical Affairs Leadership Team providing guidance & mentorship across functions - Develop & mentor a US field medical plan integrating strategy, processes, team size, and scope - Develop & implement the US external engagement strategy in partnership with Medical Leads - Continue to define structure, sizing, and recruit field medical team - Drive development of high-performing Regional Medical Directors (RMDs) with ongoing performance and talent assessment - Oversee RMD expertise and capability training in partnership with key stakeholders - Lead and manage field medical team in alignment with internal medical affairs strategy - Provide direction and prioritization to RMDs around external engagement plans, clinical trial support, scientific exchange and collaborative research within the US - Manage financial and budget accountabilities for the RMD team per corporate guidelines/requirements - Work with cross functional partners to optimally lead and support congress planning & execution - Systematically compile and report key insights from the field medical team - Develop and implement compliant field medical structural processes, systems, and policies - Partner across internal stakeholders in Medical Affairs, Clinical Development, Commercial, and Leadership in implementation and execution of field medical initiatives - Develop and manage strategic relationships with oncology thought leaders. Engage and facilitate relationships with external societies, advocacy groups, and alliance partners Qualifications - Advanced degree (MD, PhD, PharmD) in a medical or science-related specialty, although significant experience in the medical field may be considered in lieu of an advanced degree. - 10+ years of pharmaceutical or biotech related experience in Medical Affairs - Experience managing direct reports and vendor/project management preferred - Experience in thoracic and/or neuro-oncology preferred - Proven track record of matrix teamwork, leading teams, timely decision making, prioritization, and results oriented mindset in successfully achieving objectives - Strong scientific acumen required to communicate with key thought leaders, Medical Affairs personnel, Research and Development personnel, Commercial personnel, as well as other key internal and external stakeholders - Possesses superior communication skills, both oral and written, and capability to engender trust and respect of peers, subordinates, superiors, and external stakeholders - Firm understanding of the key phases, processes, and techniques that are involved in both the pre-clinical and clinical aspects of drug development - Demonstrated understanding of legal and regulatory environment of pharmaceutical industry - Adaptability to thrive in a fast-paced evolving environment - Ability to travel to Nuvation Bio Headquarters and professional congresses as appropriate (~30-50%) - An essential requirement of the position is to meet credentialing requirements for access to academic institutions, medical facilities, and organizations that are in the assigned territory. Requirements - Problem-Solver: As an action-oriented self-starter, eager to apply expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges. - Personable: Establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives. - Credible: Thorough understanding of clinical methodologies and providing sound analytical support, quickly establish credibility as a reliable resource. - Emotional intelligence, curiosity, and a knack to figure out a way to build something better. - Communication: Effectively listens, conveys, and receives ideas. Maintains a consistent flow of information. A strong presenter and effective communicator with the ability to influence stakeholders. - Accountability: Acts with a clear sense of ownership. Holds yourself and others accountable to execute all tasks at hand through seen and unforeseen circumstances with high quality and integrity. - Adaptability: Can manage in an environment of ambiguity. Embraces the change of a new system, process, technology, or idea in the organization. Benefits - Competitive Base Salary, Bonus, and Equity Plans - Unlimited Vacation and 10 Sick Days Annually - Excellent Medical, Dental, and Vision Coverage - 401K with Company Matching - And much more!

Role Description The Senior Director, Clinical Research serves as a key scientific and functional program lead as part of the CRS team. The CRS will be empowered to work collaboratively and cross-functionally to support and implement strategic objectives including clinical development plan. You will be responsible for: - Develop and support the clinical scientific strategies of the Clinical Development Plan (CDP) - Contribute to the design, start-up, execution, analysis and communication of the clinical studies for a product candidate - Review and author clinical documents as needed - Deep understanding and familiarity with assigned study and protocol requirements - Responsible for scientific oversight, data integrity and quality of the clinical trials(s) with attention to details to all aspects of assigned clinical studies - Drive and support all study related activities including: - Maintenance of clinical documents - Protocol writing, amendments, informed consent - Provide study related data to support regulatory documents (IB, regulatory documents, etc) - Site and CRA training - Site selection and activation in collaboration with clinical operation - Collaborate with clinical operation to define study activities, deliverables, instructions relating to assigned studies (e.g. IVRS, central lab, site monitoring plan, lab manual, etc) - Eligibility review - Data review, analysis and interpretation of clinical trial data - Demonstrate advanced understanding of clinical protocols - In collaboration with Clinical Operations, responsible for timely delivery of high-quality clinical study data analysis - Form and enhance working relationships with external clinical research partners/vendors to support clinical development of a drug product candidate - Support regulatory activities, medical affairs, and payer engagements; represent Nuvation Bio in external scientific and medical forums Qualifications - Advanced Degree in life sciences (medicine, pharmacy, biology, etc) - 10+ years of working experience in clinical research/development in Phase 3/pivotal space in Oncology or equivalent with demonstrated proficiency in clinical research and development - Experience in pivotal study conduct and regulatory interactions with the FDA (additional global regulatory authorities is a plus) - Extensive data listing review experience for pivotal studies - Demonstrated ability to lead the development of project strategy and to be accountable for project plans, timelines, progress, and outcomes - Expert knowledge in ICH/GCP and all aspects of clinical research and development including study design, statistics, and clinical operation - Experienced in protocol writing, data review and cleaning, ability to analyze, interpret and communicate data with clarity - Deep knowledge in disease, competitive landscape, pipeline compounds, and regulatory requirements - Strong knowledge of other key functional areas (e.g., toxicology, pharmacology, chemistry/manufacturing, clinical research and/or biometrics) appreciated - Proven leadership and collaboration skills in managing teams both directly and indirectly - Ability to work and lead in a matrix environment - Ability to effectively communicate and present data in front of external audience and at multiple levels within the organization - Ability to travel nationally and internationally as needed - An equivalent combination of education and experience may be considered Requirements - Problem-Solver: As an action-oriented self-starter, eager to apply expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges - Personable: Establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives - Credible: Thorough understanding of clinical methodologies and providing sound analytical support, quickly establishing credibility as a reliable resource - Emotional intelligence, curiosity, and a knack to figure out a way to build something better - Communication: Effectively listens, conveys, and receives ideas. A strong presenter and effective communicator with the ability to influence stakeholders - Accountability: Acts with a clear sense of ownership. Holds yourself and others accountable to execute all tasks at hand with high quality and integrity - Adaptability: Can manage in an environment of ambiguity. Embraces change and reassesses priorities as needed Benefits - Competitive Base Salary, Bonus, and Equity Plans - Unlimited Vacation and 10 Sick Days Annually - Excellent Medical, Dental, and Vision Coverage - 401K with Company Matching - And much more!

Who we are… Nuvation Bio is a biopharmaceutical company tackling some of the greatest unmet needs in oncology by developing differentiated and novel therapeutic candidates. Our vision is to significantly change the practice of oncology by developing medicines that provide truly meaningful improvements in quality of life and survival for people with cancer. What you’ll be doing Nuvation Bio is seeking a highly skilled and proactive Senior Manager, Data Acquisition & Implementation to support our enterprise data strategy and enable data-driven decision-making across the organization. This role is essential in driving how internal and external data assets are sourced, integrated, governed, and made analytics-ready. You will lead third-party data partnerships, ensure compliance and quality across data onboarding processes, and partner with cross-functional teams to support R&D, Clinical, Commercial, and Regulatory functions. This is an opportunity to join a growing biotech environment where data is central to innovation, insights, and impact. You will be responsible for… Assist in executing the data acquisition roadmap for sourcing internal and external datasets. Lead third-party data agreements, including contract negotiation, usage rights, and compliance. Organize and support Quarterly Business Reviews (QBRs) with data and technology vendors. Catalogue and assist with technical details on contracts, NDAs, data sharing agreements, ensuring alignment with legal, business, and regulatory policies. Oversee vendor audits, performance reviews, and data delivery SLAs. Data Integration & Implementation Oversee ingestion, validation, transformation, mapping, and integration of datasets into internal data platforms. Define and implement ETL/ELT workflows, data schemas, metadata, and mappings to ensure data traceability and usability. Collaborate with engineering and IT teams to ensure scalable, reliable, and secure data pipelines. Manage initiatives related to data cataloging, metadata management, and master/reference data alignment. Data Governance & Quality Execute data quality checklists and enforce data standards, metrics, and KPIs (completeness, consistency, timeliness, accuracy). Identify, investigate, and resolve data quality issues; drive root cause analysis and remediation plans. Maintain and enhance data governance policies, including access control, privacy (e.g., HIPAA, GDPR), and security compliance. Ensure robust documentation of data assets, including data dictionaries, lineage, and source trust scores. Align with cross functional partners on data quality checklist Cross-Functional Collaboration Communicate project status, risks, timelines, and outcomes to stakeholders and senior leadership. Define and improve internal processes for data acquisition and onboarding (intake, validation, deployment, maintenance). Collaborate with Legal, R&D, Clinical, Commercial, and Regulatory teams to ensure data assets meet business needs. Process Improvement & Strategic Enablement Promote data management best practices across documentation, automation, and reusability. Support budgeting, forecasting, and resource planning related to data acquisition and implementation projects. What Knowledge & Experience you'll bring to us... 5–8 years of professional experience in Data Management, Data Strategy, Data Quality, or Analytics roles within biotech, pharma, or life sciences. Proven experience managing third-party data vendors, contracts, and licensing agreements. Strong understanding of data integration (ETL/ELT), data modeling, metadata, and cataloging practices. Experience applying data quality frameworks and maintaining compliance with regulatory/privacy standards (e.g., HIPAA, GDPR). Proficiency in SQL and experience with data pipeline tools and platforms. Strong communication, vendor negotiation, and stakeholder engagement skills. Behavioral skills to be successful... Problem-Solver - As an action-oriented self-starter, you’re eager to apply your expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges. Personable - You establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives. Credible - Thorough understanding of clinical methodologies and providing sound analytical support, you quickly establish credibility as a reliable resource. Emotional intelligence , curiosity, and a knack to figure out a way to build something better Communication - Effectively listens, conveys, and receives ideas. Maintains a consistent flow of information. A strong presenter and effective communicator with the ability to influence stakeholders. Accountability - Acts with a clear sense of ownership - whether the task is in their role description. Holds yourself and others accountable to execute all tasks at hand through seen and unforeseen circumstances with high quality and integrity. Adaptability - Can manage in an environment of ambiguity. Embraces the change of a new system, process, technology, or idea in the organization. You could reassess priorities, alter goals and take risks. What we have for you! Competitive Base Salary, Bonus, and Equity Plans Unlimited Vacation and 10 Sick Days Annually Excellent Medical, Dental, and Vision Coverage 401K with Company Matching and much more! The base pay offered will take into account internal equity and also may vary depending on the candidate’s job-related knowledge, skills, experience, and location among other factors. Our full-time regular positions also include an annual performance-based bonus and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, depending on the level and position offered. Disclaimer Nuvation Bio, Inc. is an equal opportunity employer, and, in accordance with applicable federal, state, and/or local law, all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by the law. This job description reflects the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to this job. Nothing restricts management’s right to assign or reassign duties and responsibilities to this job at any time.