Mirum Pharmaceuticals, Inc.

• Understands and effectively communicates complex scientific information • Develops and implements strategic region-level business plans • Collaborates cross-functionally with internal stakeholders (e.g., Marketing, Market Access, Medical, Operations, Compliance) • Drives innovative, accountable, and entrepreneurial approaches to business challenges • Demonstrates strong organizational and time management skills • Exhibits a strong commitment to customer experience and standards of excellence • Applies strong business acumen to inform decision-making • Demonstrates high integrity and adherence to compliance standards • Demonstrates adaptability and effectiveness in fast-paced, dynamic, and collaborative environments

• Collaborates across all appropriate functional groups to support ongoing clinical trials, medical and scientific affairs research initiatives, and other scientific affairs activities for the adult hepatology program. • Supports and drives scientific and clinical communications for internal and external stakeholders, including supporting advisory boards related to adult liver disease indications. • Leverages expertise and relationships within adult hepatology and gastroenterology to support patient enrollment for the adult liver clinical research studies, while working closely with the clinical study leads, the CTLs and VP of Clinical Development. • Identifies knowledge gaps for existing areas of interest for the program and develops strategy to mitigate these gaps utilizing internal resources as well as external scientific collaborations. • Leads and collaborates across appropriate functional groups to execute compassionate use and expanded access programs for Brelovitug and Volixibat. • Oversees both internal and external research activities and initiatives such as, but not limited to, natural history studies, collaborative forums, real world data registries, data mining for areas of interest for publication, and other ongoing and future research efforts. • Leverage expertise in liver disease to support Safety and Regulatory teams. • Leverages analytical skills in discovering data insights from clinical research data, including literary research of relevant clinical data. • Support strategic publication planning and development and editing of conference abstracts, posters, presentations, and manuscripts to support programs, and execution of the strategic publication plan. • Works closely with other members of the medical affairs infrastructure.

• Understands and effectively communicates complex scientific information • Develops and implements strategic region-level business plans • Collaborates cross-functionally with internal stakeholders (e.g., Marketing, Market Access, Medical, Operations, Compliance) • Drives innovative, accountable, and entrepreneurial approaches to business challenges • Demonstrates strong organizational and time management skills • Exhibits a strong commitment to customer experience and standards of excellence • Applies strong business acumen to inform decision-making • Demonstrates high integrity and adherence to compliance standards • Demonstrates adaptability and effectiveness in fast-paced, dynamic, and collaborative environments

• Drive awareness and understanding of HDV among Infectious Disease specialists, community-based HBV treaters, and Advanced Practice Providers. • Educate healthcare professionals on the relationship between HBV and HDV, including the critical role of HBsAg in HDV replication and disease progression. • Provide education about HDV screening and testing protocols within HBV patient populations. • Identify barriers to diagnosis and collaborate with stakeholders to improve patient identification and referral processes. • Develop and execute comprehensive account plans for prioritized institutions, health systems, community practices, and referral networks. • Identify key stakeholders involved in HDV care pathways across clinical, operational, and administrative functions and provide disease education information where appropriate. • Identify geographic or institutional gaps in HDV disease awareness, screening education, and referral-process understanding. • Establish and strengthen referral pathways between community providers, Infectious Disease specialists, hepatology centers, and transplant programs. • Leverage data, insights, and customer feedback to continuously refine account strategies. • Build trusted relationships with key opinion leaders and emerging HDV advocates. • Facilitate peer-to-peer education and disease awareness initiatives. • Identify opportunities to advance HDV testing, diagnosis, and patient management practices across local and regional networks. • Compliantly collaborate with Marketing, Medical Affairs, Market Access, Patient Services, Advocacy, and Commercial leadership to execute integrated account strategies. • Share field insights to inform market development, launch readiness, and future commercial planning. • Contribute to the development of best practices and scalable approaches for HDV market activation. • Assess account readiness and identify gaps in diagnostic, referral, and infrastructure. • Support disease-state education, screening awareness, diagnostic pathway understanding and referral process education. • Maintain a deep understanding of evolving HDV market dynamics.

• Responsible for disease-state education and account-readiness activities in Hepatitis Delta Virus (HDV). • Work across Infectious Disease, and community-based healthcare providers caring for patients with chronic Hepatitis B Virus (HBV) infection. • Drive awareness and understanding of HDV among Infectious Disease specialists, community-based HBV treaters, and Advanced Practice Providers. • Educate healthcare professionals on the relationship between HBV and HDV. • Provide education about HDV screening and testing protocols within HBV patient populations. • Identify barriers to diagnosis and collaborate with stakeholders to improve patient identification and referral processes. • Develop and execute comprehensive account plans for prioritized institutions, health systems, community practices, and referral networks. • Identify key stakeholders involved in HDV care pathways and provide disease education information. • Build trusted relationships with key opinion leaders and facilitate peer-to-peer education.

• As Regional Account Manager, you are the regional business owner with focus on increasing HCP awareness and understanding of promoted Mirum product • Identifies and establishes strong relationships with key thought leaders and customers; demonstrated ability to recognize and devote the necessary time and resources needed to engage with HCP’s to create advocates • Possesses an entrepreneurial approach with a focus on ownership and accountability to maximize/exceed individual and company goals • Understand healthcare trends in the Rare Disease community and apply strategies to mitigate account access challenges • Employ strong organizational and analytical skills to optimize growth, including the ability to analyze business data to develop strategic and actionable business plans • Demonstrates and enhances Mirum’s culture of compliance, integrity, and transparency • Development and maintain strong partnerships across commercial, compliance, medical affairs functions. • Drive change through influence and innovation

• As Regional Account Manager, you are the regional business owner with focus on increasing HCP awareness and understanding of promoted Mirum product • Identifies and establishes strong relationships with key thought leaders and customers; demonstrated ability to recognize and devote the necessary time and resources needed to engage with HCP’s to create advocates • Possesses an entrepreneurial approach with a focus on ownership and accountability to maximize/exceed individual and company goals • Understand healthcare trends in the Rare Disease community and apply strategies to mitigate account access challenges • Employ strong organizational and analytical skills to optimize growth, including the ability to analyze business data to develop strategic and actionable business plans • Demonstrates and enhances Mirum’s culture of compliance, integrity, and transparency • Development and maintain strong partnerships across commercial, compliance, medical affairs functions • Drive change through influence and innovation

• Identifies, can gain access to, and develops professional relationships with thought leaders and other healthcare professionals • Supports research initiatives across development and provides support to clinical site investigators • Serves as a liaison between HCPs who express interest in conducting investigator-initiated research • Engages in scientific exchange in response to HCP requests • Effectively articulates relevant scientific and clinical information relative to the therapeutic area to HCPs and researchers • Utilizes scientific resources to deliver impactful presentations in various settings • Provides accurate and unbiased assessment of community needs to senior management • Within PhRMA guidelines, supports company-sponsored research, investigator-initiated research, and publications • Supports planning and execution of advisory boards • Stays abreast of emerging scientific literature and clinical data • Supports congress and conference strategy, providing scientific support and communication of scientific insights • Fully compliant with all company SOPs, regulatory requirements, and applicable laws • Completes other responsibilities in a timely manner, as assigned

• Own and deliver Zone business performance across the liver portfolio with a strategic, big-picture mindset • Drive change and innovation • Develop and execute zone-specific business plans aligned to national strategy • Analyze market trends, competitive dynamics, and performance data to inform actions • Lead, coach, and develop first-line leaders to maximize team effectiveness • Build a strong leadership pipeline and succession plans • Foster a culture of accountability, engagement, and continuous improvement • Ensure consistent and high-quality execution of brand strategy in the field • Monitor KPIs and drive disciplined performance management • Identify and scale best practices across regions • Partner with Marketing, Market Access, Medical Affairs, Patient Services and Operations • Ensure alignment on strategy and coordinated execution • Provide field insights to inform brand planning and lifecycle strategy • Maintain strategic relationships with key opinion leaders (KOLs) and top accounts • Understand regional nuances in referral patterns and treatment pathways • Support teams in navigating complex access and reimbursement environments • Ensure all activities comply with regulatory, legal, and company policies • Model integrity and patient-first decision making • Reinforce a culture of compliance across the organization

• Develop and communicate the strategic vision and operational plan for engaging KOLs. • Develop and oversee development and execution of individual KOL Mapping KOLs plans. • Partner closely with the Director, Marketing – KOL Strategy and Congress Planning to ensure alignment. • Build and maintain productive, collaborative, and compliant relationships with peers leading teams in Marketing, Market Access, Patient Services, and Medical Affairs. • Work closely with the Field Sales team on the execution of all thought leader-related initiatives and programs. • Build mechanisms to collect insights, synthesize and integrate them, and communicate to brand to inform tactics • Bring thought leaders closer to Mirum by ensuring compliant, value-added connections across the organization. • Collaborate with Medical Leadership on engagement strategy and planning as appropriate, including support and coordination of commercial advisory boards. • Engage with KOLs to solicit feedback that shapes and informs brand strategy. • Contribute Marketing strategy for conferences/congresses including sponsorships, communication/messaging, and advocacy group engagement. • Work in partnership with the Marketing portfolio leaders and field leadership to develop appropriate KPIs and metrics to support the brand marketing and executional goals. • Act as primary point of contact for the field, maintaining an effective two-way dialogue on KOL engagement, potential speaker identification, and up-and-coming thought leaders and experts. • Analyze market data, confirm data reliability and inform team stakeholders to make informed decisions. • Proactively engage partners in Legal and Compliance to ensure programs and processes are being delivered with the highest ethical standards