Iambic Therapeutics, Inc

Role Description We are seeking a talented and motivated Cloud Ops Engineer to join the tightly integrated technology and drug discovery operation at Iambic Therapeutics. You will work in the Software organization and closely with the ML organization to help drive the Cloud Ops Roadmap, leading and supporting delivery of the roadmap goals for projects across the organization. You will work with teams developing and deploying Iambic’s drug discovery platform, Computational Science applications, and Machine Learning models. You will also help deliver and support ISO 27001 compliant Cloud Ops processes. This job fully supports remote work but is preferably in Boston (with workspace support). Qualifications - Minimum of 12 years of related experience with a bachelor’s degree; or 10 years and a master’s degree; or equivalent experience. - Strong understanding of CI/CD pipelines. - Strong Infrastructure as Code skills – for example in Docker, Packer/Ansible and Terraform/Terragrunt. - Strong understanding of AWS services and underlying technologies such as AWS IAM service and managing Kubernetes as a service (AWS EKS) including managing zero-downtime upgrades and debugging issues with deployments, controllers, etc. Deployed in the cluster. - Strong understanding of computer networks: - TCP/IP protocols. - IP block allocation across an organization. - Routing and VPN protocols. - AWS networking: VPCs, Transit Gateways, Customer Gateways, VPNs, flow logs, security groups, NACLs, etc. - Cloudflare networking experience. - Understanding of issues facing ML deployments including model training and inference challenges. - Ability to communicate with a variety of teams including IT, Computational Scientists, Software Developers, Cloud Ops, and ML engineers. Requirements - Support and contribute to the Cloud Ops roadmap, aligning infrastructure initiatives with business priorities. - Provide technical leadership and drive architecture decisions across platform and infrastructure teams. - Lead the design and evolution of scalable, highly available AWS cloud infrastructure. - Build and operate production systems with a strong focus on reliability, performance, and cost efficiency. - Design and manage cloud networking (VPN, VPC, routing, DNS, load balancing, secure connectivity). - Implement Infrastructure as Code (Terraform) and automate provisioning and operations. - Troubleshoot complex issues across distributed systems, including networking and performance bottlenecks. - Apply security best practices and support the ISO 27001 compliance frameworks. - Improve observability, CI/CD pipelines, and overall operational maturity. - Mentor engineers in Cloud Services and influence Cloud Ops best practices across the org. Benefits - Industry leading competitive pay. - Company paid healthcare. - Flexible spending accounts. - Voluntary life insurance. - 401K matching. - Uncapped vacation. - Brand-new state-of-the-art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

Role Description We are seeking a Machine Learning Scientist to join the Enchant team at Iambic Therapeutics. Our mission is to deliver better medicines through innovation in AI-based discovery technologies. In this role, you will research, develop, and scale Enchant — our multimodal transformer model trained on a wide variety of biomedical data — pushing the boundaries of what large-scale foundation models can achieve in drug discovery. This role spans architecture research through to production deployment. - Research and implement architectural improvements to large-scale multimodal transformer models for biomedical applications - Investigate hybrid modeling approaches that combine learned representations with domain-informed structure or inductive biases - Optimize training pipelines for efficiency, stability, and scalability across many-GPU clusters - Develop and apply inference optimization techniques to support deployment in interactive discovery workflows - Design and maintain benchmarking and evaluation frameworks that track model quality across modalities and downstream tasks - Collaborate with ML and software engineering colleagues to deploy and operationalize models - Partner with computational chemists, medicinal chemists, and biologists to ensure model development is grounded in drug discovery needs - Communicate results to internal teams, external partners, and at conferences - Write high-quality research and engineering code: refactor, test, document, and package ML components to support team velocity - Depending on level: - Mentor interns and junior team members through technical guidance, code reviews, and best practices in ML experimentation - Contribute to the strategic research roadmap for Enchant and related multimodal technologies Qualifications - Required: - MS in ML/CS or a computational STEM field with relevant industry or research experience, or PhD or equivalent industry experience demonstrating comparable depth - Strong Python and PyTorch experience, including implementing and training deep learning models end-to-end - Demonstrated experience training transformer models at scale - Strong engineering habits: reproducible experimentation, clean code, testing, and performance-minded debugging - Comfort working with modern ML infrastructure (e.g., Docker, CUDA, Kubernetes, experiment tracking such as Weights & Biases) - Desired: - Experience with multimodal or multi-task model architectures - Training and inference optimization (e.g., mixed precision, kernel optimization, quantization, distributed strategies) - Familiarity with biomedical, chemical, or biological data domains - Distributed training at scale - HPC or large-scale training operations experience Location - Remote (US or UK) - On-site available in Bristol, UK and Boston, US Benefits - Industry leading competitive pay - Company paid healthcare - Flexible spending accounts - Voluntary life insurance - 401K matching - Uncapped vacation - Brand-new state-of-the-art facility in beautiful San Diego with an onsite gym and dining - Easy access to great places to live and play

JOB SUMMARY The Contract Senior Talent Acquisition Partner – AI / Machine Learning provides full-cycle recruiting support for technical hiring initiatives at Iambic Therapeutics during a defined engagement period. This role partners closely with hiring managers and the Talent Acquisition lead within HR to drive hiring for machine learning, artificial intelligence, and software engineering roles critical to the company’s technology platform. Operating as a hands-on recruiting partner, the Contract Senior Talent Acquisition Partner proactively sources and engages qualified talent, manages searches from intake through offer and close, and ensures a positive candidate experience while adhering to established processes and compliance standards. This role is ideal for an experienced technical recruiter who thrives in fast-paced environments and has a strong track record of identifying and engaging top talent in machine learning, AI research, and engineering. This position supports hiring across technical and research teams. KEY RESPONSIBILITIES - Manage full-cycle recruiting for technical roles, including intake meetings, sourcing, screening, interview coordination, offer support, and closing candidates - Drive efficient hiring processes with a focus on speed, quality, and strong candidate experience - Partner closely with hiring managers to understand role requirements, hiring priorities, and candidate profiles - Execute sourcing and recruiting strategies aligned with business needs and approved hiring plans - Provide regular updates and maintain proactive communication with hiring managers and HR throughout the recruiting process - Build and maintain pipelines of qualified candidates, including both active and passive talent - Leverage recruiting tools and resources including LinkedIn Recruiter, referrals, networking, and targeted outreach to identify high-quality candidates - Support offer development and negotiation in partnership with HR and hiring managers, following established guidelines - Maintain accurate and compliant candidate records within the Ashby applicant tracking system - Ensure recruiting activities align with internal processes and relevant compliance standards - Deliver a professional and consistent candidate experience throughout the recruiting lifecycle - Represent the company positively in all candidate, vendor, and external interactions QUALIFICATIONS - Bachelor’s degree in Business Administration, Human Resources, or a related field, or equivalent experience - 6+ years of full-cycle recruiting experience, with a strong focus on technical recruiting - Experience recruiting for scientific, technical, or specialized roles in a fast-paced environment - Proven ability to manage multiple searches simultaneously while maintaining strong candidate and hiring manager relationships - Strong consultative partnership skills with the ability to influence and guide hiring managers - Excellent verbal and written communication skills with the ability to manage sensitive and confidential information - Solid understanding of recruiting compliance standards and best practices - Experience using Asby ATS strongly preferred - LinkedIn Recruiter experience required; familiarity with talent market intelligence tools is a plus ABOUT IAMBIC THERAPEUTICS Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai. MISSION & CORE VALUES Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

JOB SUMMARY The Contract Life Science Recruiter provides full-cycle recruiting support across key hiring priorities at Iambic Therapeutics for a defined engagement period. This role partners closely with hiring managers and the Talent Acquisition lead within HR to deliver timely, high-quality hiring outcomes in support of company growth. Operating as a hands-on recruiting partner, the Contract Senior Talent Acquisition Partner proactively sources and engages qualified talent, manages searches from intake through offer and close, and ensures a positive candidate experience while adhering to established processes and compliance standards. This role is ideal for a highly execution-focused recruiter who thrives in fast-paced, high-growth environments and is comfortable managing multiple complex searches simultaneously. This position supports hiring across scientific, technical, and corporate functions. KEY RESPONSIBILITIES - Manage full-cycle recruiting for assigned roles, including intake meetings, sourcing, screening, interview coordination, offer support, and closing candidates - Drive efficient hiring processes with a focus on speed, quality, and strong candidate experience - Partner closely with hiring managers to understand role requirements, hiring priorities, and candidate profiles - Execute sourcing and recruiting strategies aligned with business needs and approved hiring plans - Provide regular updates and maintain proactive communication with hiring managers and HR throughout the recruiting process - Build and maintain pipelines of qualified candidates, including both active and passive talent - Leverage recruiting tools and resources including LinkedIn Recruiter, referrals, networking, and targeted outreach to identify high-quality candidates - Support offer development and negotiation in partnership with HR and hiring managers, following established guidelines - Maintain accurate and compliant candidate records within the Ashby applicant tracking system - Ensure recruiting activities align with internal processes and relevant compliance standards - Deliver a professional and consistent candidate experience throughout the recruiting lifecycle - Represent the company positively in all candidate, vendor, and external interactions QUALIFICATIONS - Bachelor’s degree in Business Administration, Human Resources, or a related field, or equivalent experience - 3+ years of full-cycle recruiting experience, with experience in biotech, life sciences, or pharmaceutical recruiting strongly preferred - Experience recruiting for scientific, technical, or specialized roles in a fast-paced environment - Proven ability to manage multiple searches simultaneously while maintaining strong candidate and hiring manager relationships - Strong consultative partnership skills with the ability to influence and guide hiring managers - Excellent verbal and written communication skills with the ability to manage sensitive and confidential information - Solid understanding of recruiting compliance standards and best practices - Experience using Asby ATS strongly preferred - LinkedIn Recruiter experience required; familiarity with talent market intelligence tools is a plus ABOUT IAMBIC THERAPEUTICS Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai. MISSION & CORE VALUES Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

JOB SUMMARY This role leads Quality Systems and Compliance, with responsibility for designing and implementing a Quality Management System (QMS) that supports current clinical development programs and the organization’s growing pipeline. The role partners closely with Regulatory, Medical, Clinical, R&D, and Technology leadership to ensure quality systems enable innovation, maintain compliance, and support continuous inspection readiness across U.S. and global clinical programs. This job is based in San Diego, CA, or can be remote, and based in the US KEY RESPONSIBILITIES - Lead the design, implementation, and ongoing effectiveness of the Quality Management System (QMS) - Establish policies, procedures, and governance frameworks covering core quality processes, including document control, change management, deviations, CAPA, training, and risk management - Act as a strategic quality partner to Regulatory, Medical, Clinical Operations, R&D, and CMC teams - Define and execute a quality roadmap that translates regulatory and quality requirements into practical, scalable operating models aligned with current compliance needs and future organizational growth - Partner with Regulatory and Clinical teams to ensure quality systems support global clinical trial programs, including alignment across regions. - Proactively identify and mitigate compliance risk through data-driven monitoring and governance - Define key quality metrics and dashboards to monitor system health, compliance trends, and continuous improvement opportunities - Foster a culture of accountability, transparency, and quality ownership across the organization - Provide quality oversight and coordination for health authority interactions, internal audits, and third-party audits, as applicable - Ensure inspection readiness for U.S. and global clinical programs through established quality systems, governance, and cross-functional alignment QUALIFICATIONS Education & Experience: - Bachelor’s degree in chemistry, biology, engineering, or related health science Experience: - 10+ years of progressive experience in Quality Systems, Compliance, and/or Quality leadership within a regulated industry - Experience designing, implementing, or improving Quality Management Systems - Experience leading initiatives, projects, or teams in matrixed or growing organizations - Experience partnering with cross-functional teams, including Regulatory, Medical, Clinical Operations, R&D, and Technology - Strong understanding of risk-based quality systems and continuous improvement concepts - Ability to define and use quality metrics to monitor system performance and compliance trends - Clear, effective communicator with the ability to influence and align stakeholders - Comfortable operating in environments with evolving processes and priorities. - Experience with electronic quality management systems (eQMS); Veeva experience a plus - Familiarity with global regulatory expectations applicable to clinical development, including U.S. and international considerations. - Working knowledge of GCP and applicable GMP principles as they relate to clinical quality systems - Experience supporting inspection readiness, audits, or regulatory interactions through quality systems and cross-functional collaboration - Demonstrated ability to translate regulatory and quality requirements into practical, scalable processes ABOUT IAMBIC THERAPEUTICS Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai. MISSION & CORE VALUES Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies. PAY AND BENEFITS We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.