Role Description PSI Medical Monitors provide medical input to global clinical studies and advise the teams and business partners, while always focusing on patients' safety and well-being. Home-Based in United States Responsibilities: - Acts as the primary point of contact for all parties on all trial-specific medical and safety-related questions - Provides input for responses to regulatory authorities and Institutional Review Boards (IRBs)/Independent Ethics Committees (IECs) on trial-specific medical and safety-related questions - Monitors trial participant safety - Participates in trial participant recruitment boost and retention activities - Presents on medical matters at kick-off and investigator meetings - Trains trial team in the therapeutic area and medical aspects of the protocol - Develops and reviews trial-specific documents within the scope of medical monitoring - Manages ongoing trial risks related to medical monitoring - Performs ongoing medical review of the operational clinical trial database; provides support to Medical Reviewer(s) assigned to the trial - Reviews protocol deviations - Reviews RAE reports, writes and/or reviews SAE narratives, supports Pharmacovigilance team with outstanding safety queries, interacts with sponsor on site safety issues - Reviews IND/SUSAR Safety Reports, updates/amendments to essential trial records, and annual IND reports with sponsor data (per sponsor request) - Participates in management of trial-related committees (e.g., independent data monitoring committee (IDMC)/adjudication committees) as described in the corresponding trial-specific charter(s) - Supports Pharmacovigilance, Medical Data Review and Data Management with reconciliation of safety and operational clinical trial databases - Reviews clinical study reports (CSRs), including safety narratives and tables, figures, and listings (TFLs) - Provides medical expertise on an as-needed basis in trials where medical monitoring is not a contract deliverable - Prepares for and participates in trial audits, follows up on audit findings - Participates in feasibility assessment of potential and ongoing trials in the country/region - Participates in bid defense meetings and other interactions with clients - Acts as a medical expert and provides therapeutic expertise to other PSI departments Qualifications - Medical Doctor degree required - US Board Certification in psychiatry required - Experience as a practicing psychiatrist (minimum of 10 years) - Clinical Research experience preferred - Proficiency with MS Office applications - Communication, presentation and analytical skills - Problem-solving, team and detail-oriented Benefits - As part of PSI's Medical Monitoring team, you will join our international group of medical professionals - Build a career on the frontline of medical science - Use your knowledge and expertise to help bring new medications to patients that need them

Role Description PSI Medical Monitors provide medical input to global clinical studies and advise the teams and business partners, while always focusing on patients' safety and well-being. Home-Based in Canada. Responsibilities: - Acts as the primary point of contact for all parties on all trial-specific medical and safety-related questions. - Provides input for responses to regulatory authorities and Institutional Review Boards (IRBs)/Independent Ethics Committees (IECs) on trial-specific medical and safety-related questions. - Monitors trial participant safety. - Participates in trial participant recruitment boost and retention activities. - Presents on medical matters at kick-off and investigator meetings. - Trains trial team in the therapeutic area and medical aspects of the protocol. - Develops and reviews trial-specific documents within the scope of medical monitoring. - Manages ongoing trial risks related to medical monitoring. - Performs ongoing medical review of the operational clinical trial database; provides support to Medical Reviewer(s) assigned to the trial. - Reviews protocol deviations. - Reviews RAE reports, writes and/or reviews SAE narratives, supports Pharmacovigilance team with outstanding safety queries, interacts with sponsor on site safety issues. - Reviews IND/SUSAR Safety Reports, updates/amendments to essential trial records, and annual IND reports with sponsor data (per sponsor request). - Participates in management of trial-related committees (e.g., independent data monitoring committee (IDMC)/adjudication committees) as described in the corresponding trial-specific charter(s). - Supports Pharmacovigilance, Medical Data Review and Data Management with reconciliation of safety and operational clinical trial databases. - Reviews clinical study reports (CSRs), including safety narratives and tables, figures, and listings (TFLs). - Provides medical expertise on an as-needed basis in trials where medical monitoring is not a contract deliverable. - Prepares for and participates in trial audits, follows up on audit findings. - Participates in feasibility assessment of potential and ongoing trials in the country/region. - Participates in bid defense meetings and other interactions with clients. - Acts as a medical expert and provides therapeutic expertise to other PSI departments. Qualifications - Medical Doctor degree required. - Canada Board Certification in psychiatry required. - Experience as a practicing psychiatrist (minimum of 10 years). - Clinical Research experience preferred. - Proficiency with MS Office applications. - Communication, presentation and analytical skills. - Problem-solving, team and detail-oriented. Benefits - As part of PSI's Medical Monitoring team, you will join our international group of medical professionals, build a career on the frontline of medical science and use your knowledge and expertise to help bring new medications to patients that need them. - Compensation: CAD 170,000 - CAD 185,000 yearly.

• In addition to providing therapy services, the Associate Clinical Director partners with the Clinical Director and practice leadership team to support ethical, compliant, and high-quality care in accordance with company policies and applicable regulatory and professional standards. • Serve as an operational leader focused on provider onboarding, supervision support, clinician development, training delivery, and follow-through on quality improvement initiatives established by Clinical Leadership. • Train new clinicians on documentation principles, clinical standards, and organizational policies and conduct ongoing performance reviews. • Provide individual and peer coaching to clinicians to support professional growth, clinical excellence, and ethical practice. • Ensure compliance with BBS standards for supervision, ethical practice, and clinical documentation in conjunction with Clinical Director and Leadership team. • Provide therapy services to a caseload of clients, maintaining a clinical caseload of 12-15 clients per week.

Role Description We are seeking a Senior Regional Medical Director, MSL Team Lead to serve as Solid Biosciences’ senior scientific representative within an assigned geography, drive meaningful engagement with key external stakeholders, and generate actionable insights to inform development, evidence generation, and Medical Affairs strategy. This foundational role will help establish Solid’s U.S. Medical Affairs presence while supporting clinical development, trial readiness, and scientific exchange activities across the Duchenne and broader rare disease portfolio. As the Medical Affairs organization grows, the Senior Regional Medical Directors will play a key role in building and leading the U.S. field medical organization and are expected to transition into regional leadership positions overseeing Medical Science Liaison (MSL) teams. This is a remote, US-based role, reporting to the Executive Director, Global Head of Medical Affairs. Key Position Responsibilities - Scientific Engagement - Develop and maintain peer-to-peer scientific relationships with key opinion leaders, investigators, and multidisciplinary care teams. - Execute regional medical engagement plans aligned with Global Medical Affairs strategy. - Represent Solid at scientific congresses, advisory boards, investigator meetings, and other external forums. - Provide scientific education and exchange regarding Solid’s research and development programs. - Clinical Development & Trial Readiness - Gather insights to inform protocol design, endpoint selection, and development strategy. - Support future launch preparedness through deep understanding of regional care pathways and treatment landscapes. - Insights & Evidence Generation - Capture, synthesize, and communicate actionable medical insights. - Identify opportunities for real-world evidence generation, natural history collaborations, and investigator-sponsored research. - Support scientific communication and publication priorities through stakeholder engagement. - Leadership Responsibilities - Contribute to the development of Solid’s U.S. field medical organization. - Support recruitment, onboarding, and mentoring of future MSL team members. - Establish best practices for scientific engagement and insight gathering. - Transition into regional leadership responsibilities as the MSL organization expands. Qualifications - Advanced scientific or clinical degree (MD, PharmD, PhD, DNP). - 10+ years of biotechnology, pharmaceutical, clinical, or academic experience. - Rare disease, neuromuscular disease, genetics, or gene therapy experience preferred. - Demonstrated success in KOL engagement and scientific exchange. - Ability to travel extensively within assigned territory. Requirements - The base compensation range for this role is: $281,611 – $325,826. - Base salary offered is determined through an internal analysis utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity. - Regular employees are eligible to receive both short-term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward individual performance and align incentives to Solid’s long term company performance. Benefits - Competitive Health and Dental programs with flexible plan offerings, including FSA and HSA programs. - 401(k) program participation with competitive company matched contributions. - Eligibility to participate in Solid’s Employee Stock Purchase Plan. - Mobile phone subsidy for eligible employees. - Tuition Reimbursement. - Vision Coverage. - Life Insurance. - Voluntary Pet Insurance. - Employee Discount Program on Travel, Entertainment, and Services. - Daily Subsidized Lunch Delivery (onsite @ Hood Park). - Free Onsite Full-Service Gym (onsite @ Hood Park). - Employee Parking (onsite @ Hood Park).