Role Description The Medical Director provides physician support to Enterprise Clinical Services operations, the organization responsible for the initial clinical review of service requests for Enterprise Clinical Services. The Medical Director collaborates with Enterprise Clinical Services leadership and staff to establish, implement, support, and maintain clinical and operational processes related to benefit coverage determinations, quality improvement, and cost effectiveness of service for members. The Medical Director's activities primarily focus on the application of clinical knowledge in various utilization management activities with a focus on pre-service benefit and coverage determination or medical necessity (according to the benefit package), and on communication regarding this process with both network and non-network physicians, as well as other Enterprise Clinical Services. The Medical Director collaborates with a multidisciplinary team and is actively involved in the management of medical benefits. The collaboration often involves the member’s primary care provider or specialist physician. It is the primary responsibility of the medical director to ensure that the appropriate and most cost-effective quality medical care is provided to members. You’ll enjoy the flexibility to work remotely from anywhere within the U.S. as you take on some tough challenges. Primary Responsibilities: - Conduct coverage reviews based on individual member plan benefits and national and proprietary coverage review policies, render coverage determinations. - Document clinical review findings, actions, and outcomes in accordance with policies, and regulatory and accreditation requirements. - Engage with requesting providers as needed in peer-to-peer discussions. - Be knowledgeable in interpreting existing benefit language and policies in the process of clinical coverage reviews. - Communicate and collaborate with network and non-network providers in pursuit of accurate and timely benefit determinations for plan participants while educating providers on benefit plans and medical policy. - Communicate and collaborate with other internal partners. - Call coverage rotation. Qualifications - M.D or D.O. - Active unrestricted license to practice medicine. - Board certification in an ABMS specialty with Internal Medicine or Family Medicine preferred but other specialties can be considered. - 3+ years of clinical practice experience after completing residency training. - Demonstrated sound understanding of Evidence Based Medicine (EBM). - Proven solid PC skills, specifically using MS Word, Outlook, and Excel. Requirements - CA, OR, WA or AZ licensure or willing to obtain. - Experience in utilization and clinical coverage review. - Proven excellent oral, written, and interpersonal communication skills, facilitation skills. - Proven data analysis and interpretation aptitude. - Proven innovative problem-solving skills. - Proven excellent presentation skills for both clinical and non-clinical audiences. Benefits - Comprehensive benefits package. - Incentive and recognition programs. - Equity stock purchase. - 401k contribution (all benefits are subject to eligibility requirements). - Salary range from $248,500 - $373,000 annually based on full-time employment.

• Provide strategic guidance on industry trends, technology, and market opportunities • Support evaluation of potential investments and emerging startups • Introduce high-quality founders, investors, and ecosystem partners • Mentor and advise founders within the 16VC portfolio • Contribute to the development of 16VC’s investment theses and ecosystem initiatives

• Lead translational medicine and clinical biomarker strategy across oncology programs within and beyond the BioPharma BD portfolio. • Define and oversee biomarker plans supporting late-stage development in solid tumors within the BioPharma space (Pharma Lab Services, BD partnerships) including assay strategy, translational endpoints, data generation, data interpretation, publication planning, and regulatory filing support. • Partner closely with clinical development, bioinformatics, medical affairs, regulatory, diagnostics, and commercial teams to ensure assay development portfolio and biomarker strategies are aligned with overall BioPharma BD needs. • Work with external partners on their Natera-supported translational research efforts to help them leverage Natera capabilities to optimize the value of their projects: these may include identifying novel targets, characterizing resistance mechanisms, developing novel predictive biomarkers and next-generation clinical tools, including blood-based biomarkers, digital pathology, radiomics, and AI/ML-enabled approaches. • Support development and lifecycle strategies that enable successful product differentiation, launch readiness, reimbursement, and broader clinical adoption. • Contribute to study design and evidence-generation plans that support our BioPharma efforts across BD, Pharma Lab Services, and internal R&D. • Work with the RWD, AI, and bioinformatics teams to develop use cases for existing data and build out new concepts for new data types as they are created. • Apply translational insights to inform patient selection, development decisions, and clinical differentiation strategies for our customers. • Establish and lead strategic collaborations with BioPharma partners, academic institutions, cooperative groups, scientific consortia, and key opinion leaders. • Represent the company in external scientific and clinical initiatives that shape the future of biomarker-enabled oncology development. • Build productive external partnerships that accelerate innovation, evidence generation, and adoption of novel translational approaches. • Serve as a visible scientific leader through publications, invited presentations, advisory participation, and broader thought leadership in oncology and precision medicine. • Maintain strong credibility in the external scientific community, with the ability to engage effectively with academic leaders, consortia, and industry partners. • Contribute to the company’s scientific reputation through high-impact external presence and publication strategy.

• We are seeking a physician to serve as a Senior Medical Director to oversee global Phase 3 clinical trials and BLA (Biologic Licensing Application) filings. • The incumbent will be primarily responsible for developing and executing an integrated clinical trial programs including protocol design and medical oversight of new or ongoing studies. • They will be responsible for obtaining scientific advisory input, work with biostatisticians for phase 3 design and analyses, support regulatory interactions for product advancement, and work closely with clinical operations to provide advice and decision making regarding medical input to achieve operational excellence. • This position will provide medical insight across a myriad of functions from discovery to manufacturing are expected. • Additionally, the Medical Director will play a pivotal role in leading investigator engagements including travel to support face-to-face interaction and protocol training. • Prior experience in a mid-sized, fast-growing pharmaceutical environment is preferred, as this role will be working on product development in an extremely fast-paced and intense environment. • The Medical Director will serve as a leader on one multiple potentially pivotal programs.