• Monitor and analyze payer and LBM medical policies, coverage decisions and reimbursement trends across commercial and government payers to assess impact on company pipeline • Interpret payer and policy changes and communicate implications to the broader internal stakeholders • Clinical and product expert for the Market Access team and responsible for presenting clinical data to market access policy makers, including Medical Directors and Medical Policy groups, and meetings and conferences • Own and support the development of evidence generation plans, value propositions and technical assessment submission packages to submit to gain coverage of Caris products to assigned payers and LBMs • Engage with payer stakeholders including Medical Directors and Medical Policy contacts to communicate updates to data and to advocate for coverage of Caris's tests • Maintain policy relationships with industry, including trade associations and professional societies • Support National and State legislative initiatives advocating for coverage of evidence-based biomarkers for all cancer patients to improve access and promote health equality • Market Access representative and advocate in strategic and tactical planning within the business units, focused on evidence generation, product development, and commercialization from a Payer perspective • Partner with market access, marketing, HEOR and other related solutions teams to support the execution of business plans for the business unit • Closely track and understand professional society guidelines and technology assessments that influence payer policy decisions • Ability to work in a deadline-driven and fast-paced environment, including managing multiple projects on time and within budget completion • Ability to use expert knowledge and judgment to make sound decisions • Ability to effectively collaborate, interface, and influence with all levels of an internal organization • Ability to lead, manage, and prioritize strategies, initiatives, and workload independently and proactively in a fast-paced, entrepreneurial environment • Adaptable, open to change, and ability to work in ambiguous situations and respond to new information and unexpected circumstances • Ability to develop a value proposition and effective business case to influence medical policy • Apply outstanding problem solving, project and program management skills • Exercise strong analytical and business skills; ability to communicate effectively with high level executives • Exercise strong collaboration, influencing, project management, organizational, and change management skills • Exercise strong oral and written communication and presentation skills • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork • Maintain regular and reliable attendance • Develop and maintain payer engagement strategies to support long-term access and reimbursement goals • Lead internal training sessions to educate commercial and medical teams on payer trends and policy changes • Track and report on key performance indicators (KPIs) related to payer coverage, policy wins, and access milestones • Collaborate with Clinical Development and HEOR to align evidence generation with payer expectations • Support pricing strategy development by providing insights into payer value perception and reimbursement benchmarks • Represent the company at external policy forums, payer advisory boards, and industry coalitions

Role Description The USMA Health Systems Oncology (HSO) Director, Strategic Medical Implementation Lead, plays a critical leadership role in advancing the strategic priorities of US Medical Affairs (USMA) across a dynamic and growing portfolio. Reporting to the AVP, Health Systems Oncology, this role is a key member of the USMA Health Systems Field Medical Leadership Team and drives alignment, innovation, and execution across the Health Systems field medical enterprise. The USMA HSO Director, Strategic Medical Implementation Lead, holds primary responsibility for integrating cross-functional strategic direction into medical field execution to optimize impact across Strategic Accounts. In partnership with cross-portfolio stakeholders, the USMA HSO Director, Strategic Medical Implementation Lead, leads strategic planning, communication, and innovation initiatives to ensure coordinated, data-driven, and future-ready engagement with the evolving healthcare ecosystem. Responsibilities and Primary Activities - Enterprise Strategy Integration: - Advance non-therapeutic area strategic initiatives (i.e., quality, value and implementation) that shape the direction of USMA Health Systems field activities across Oncology portfolio. - Lead strategic alignment across multiple Regional Medical and Scientific Director (RMSD) teams and the Health Systems (HS) team, including Medical Account Planning, joint initiatives, etc. - Serve as a critical connector between overall Health Systems strategy and product-level strategies, ensuring collaboration with Integrated Account Management (IAM), Strategic Insights Team, Payer Marketing, Organized Customer Access & Reimbursement (OCAR), and other enterprise partners. - Leadership & Strategic Execution: - Influence field medical planning through collaboration with FMADs, PASLs, and SDMAs to ensure coordinated execution and prioritization. - Support strategic communications, leadership alignment, and executional excellence across all touchpoints between Headquarters and the Field. - Partner with leadership on culture-shaping initiatives, team development, and performance enablement to ensure a high-performing, innovative, and agile field medical organization. - Field Medical Innovation and Enablement: - Drive simplification, innovation, efficiency and effectiveness across field medical health systems, tools, and processes to increase agility and measurable outcomes. - Lead and evolve strategic frameworks for initiative reporting, Medical Affairs / Commercial meetings, medical leadership reviews, and impact communications. - Manage and enhance the US Value & Implementation Goal tracking, aligning resources to support major initiatives with robust 30/60/90-day milestone tracking. - Performance Measurement & Analytics: - Lead Health Systems Oncology value creation by identifying areas of high impact and translating into messaging that resonates with senior leadership. - Develop and assess team data and analytics via KPI dashboards, scorecards, and other analytics systems to track performance against team goals and impact metrics. - Identify and accelerate best practices across HSO MADs and cross-functional partners through data-driven insights. - Co-lead the development of impact reports in partnership with the Executive Director to highlight progress and strategic contributions. Qualifications - Advanced healthcare/science doctoral degree (e.g., MD, PharmD, PhD) - 5+ years field medical affairs experience, including: 2 or more years as a HS/Payer Medical Liaison OR equivalent - Agile mindset, ability to multitask among many competing priorities, and ability to work across a portfolio along the product life-cycle - Ability to handle a demanding and changing workload and respond efficiently to timelines and changing market events - Excellent interpersonal, analytical, strategic, and tactical planning, project management, communication, and organization skills - Exceptional ability to effectively communicate information to internal and external stakeholders at all levels (e.g., senior leadership, management and individual contributor) and create presentation concepts and slides that are visually appealing with compelling content - Commitment to keeping team members, departmental colleagues (as appropriate), and management fully apprised of project/initiative status and issues - Proven ability to work with cross-functional Matrix teams and collaborate across multiple stakeholder groups (e.g., therapeutic areas) - Working knowledge of development and application of evidence base, real world analytics, health economics and outcomes research in defining the value proposition of products - Proven track record of contribution to commercial and medical development strategies within the pharmaceutical industry - Strategy lead and/or additional experience in a strategy and operations type role preferred (including experience working in managed care /health systems) - Team lead or management experience preferred but not required Required Skills - Clinical Oncology - Immuno-Oncology - Medical Affairs - Medical Knowledge - Performance Measurement - Pharmaceutical Medical Affairs - Professional Networking - Project Management - Strategic Insights - Strategic Planning - Strategic Thinking Benefits - Medical, dental, vision healthcare and other insurance benefits (for employee and family) - Retirement benefits, including 401(k) - Paid holidays, vacation, and compassionate and sick days

• Develop, design and manage the technical component of engagements and solutions that align with business requirement • Managing resources that will build and configure RPA deployments and Conversational AI models to improve their accuracy and efficiency • Troubleshooting and resolving any issues related to technical implementations • Collaborating with cross-functional teams to understand their requirements and provide AI-based solutions • Collaborate with stakeholders to gather requirements, understand user needs, and define technical requirements of solutions

• Responsible for guiding the strategic product direction for department • Responsible for the product road map, development and implementation, opportunity identification, business case development, industry research, and new product introduction across the product set • Responsible for end-to-end product governance from concept to production of multiple products at a global level • Align and engage stakeholders on complex business needs into a product strategy on a global level • Lead the translation of business strategy into product strategy and roadmaps by facilitating the collaboration and alignment of business leaders and technology teams • Responsible for the overall product lifecycle of multiple enterprise-wide products including design, development and implementation and support • Ensure the ongoing funding and investment of product development and ensure the measure efficiencies gained, value realized and ROI • Ensure the overall health of the agile development process providing coaching and monitoring of the process to ensure productivity and efficiency of the development process and teams engagement • Collaborate and influence senior leadership and technology teams to negotiate and agree on proposed new systems and changes to existing systems and practices • Actively synthesize and integrate market changes and technology improvements into actionable improvements for products • Act as a thought leader by partnering closely with internal and external stakeholders to provide a global viewpoint and extend applications across use cases • Drive a sustainable cyclical process of business value, financial review, forecasting, idea generation, opportunity sizing, business case preparation, product development, and implementation • Own the end-to-end product governance from concept to production of multiple products at a global Centene level • Performs other duties as assigned • Complies with all policies and standards