• The Senior CRA plays a critical role in supporting the clinical operations team throughout the conduct of clinical trials. • This position primarily focuses on trial planning, site monitoring, data quality oversight, as well as study tracking and reporting. • Conduct regular monitoring visits to ensure the trial is conducted in accordance with the protocol and that subject safety is maintained. Verify data accuracy through comprehensive Source Document Verification (SDV). • Ensure investigational products, biological samples, and study supplies are handled according to applicable requirements, including receipt, storage, return, destruction, and accountability. • Maintain the electronic and/or paper Trial Master File (TMF) to ensure proper documentation standards are met and tasks are performed independently. • Assist in the creation, distribution, management, and archiving of essential clinical trial documents. • Assist in the preparation and maintenance of study-related materials, including but not limited to site and CRA training materials, regulatory document templates, study binders, study plans, communication records, and presentation materials. • Support training activities for clinical research teams and site staff. • Assist in the execution and management of site-related contracts. • Support the review of vendor and site contract terms and verify associated invoices for accuracy and compliance with budget. • Ensure all responsibilities are carried out in compliance with company regulations, safety policies, and standard operating procedures (SOPs). • Manage all operational aspects of clinical trials, from Study Start-up through Database Lock. • Ensure all activities adhere to stated goals, timelines, budgets, and strictly comply with applicable regulatory requirements, ICH/GCP, and Standard Operating Procedure (SOP) standards. • Provide sponsor oversight of the CRO activities for the Global Phase 3 trial. • Responsible for the overall management and oversight of all study-related vendors, including Contract Research Organizations (CROs) and Contract Labs. • Review and provide input on vendor contracts and Statements of Work (SOWs). • Assist with invoice reconciliation and financial tracking, as needed. • Serve as the primary point of contact for key vendors and stakeholders. Responsible for managing and coordinating parties to effectively facilitate issue resolution. • Investigational Product (IP) Management: Manage the Investigational Product (IP). • Review protocol deviations and data listings as needed to ensure sponsor oversight. • Assist in the development of internal SOPs and processes to ensure ongoing compliance and inspection readiness. • Build and maintain strong rapport and trust with investigators and other stakeholders. • Perform activities to ensure investigators and stakeholders are equipped with relevant information/knowledge to perform the studies as requested by the company. • Provide necessary on-site assistance and guidance to trial centers (sites) to support their execution of Photoimmunotherapy (PIT), assuming a role similar to that of a Field Clinical Technician (FCT), when required. • Other duties as mutually agreed between the candidate and the company.

• Deliver clinical trial monitoring work to a high standard • Work closely with your team and stakeholders • Coordinate all activities for setting up and monitoring a study • Complete accurate study status reports and maintain study documentation • Run sponsor generated queries efficiently and take responsibility for study cost efficiency • Participate in the preparation and review of study documentation and feasibility studies for new proposals as required • Develop and maintain strong, collaborative relationships with key stakeholders, clinical investigators, and site staff • Ensure patient safety by ensuring compliance with ICON's procedures, protocols, and regulatory requirements

• You will lead on clinical trial monitoring tasks requiring technical depth, with a focus on quality and continuous improvement. • Monitoring clinical trial sites to ensure adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards. • Conducting site visits to assess site performance, resolve issues, and provide support to ensure successful trial execution. • Collaborating with cross-functional teams to ensure timely and accurate data collection and reporting. • Providing training and guidance to site staff and other CRAs to maintain high standards of clinical trial conduct. • Building and maintaining effective relationships with site personnel and stakeholders to facilitate smooth trial operations.

Role Description We are seeking a detail-oriented Technical Research Analyst to review, analyse, and interpret client research conducted throughout the financial year. The successful candidate will transform complex technical information from multiple sources into clear, concise, and professional technical reports. This is a fully analytical and report-writing role with no administrative responsibilities. - Review and analyse client research documentation provided in various formats, including: - Technical reports - System logs - Meeting transcripts - Research documentation - Supporting technical materials - Identify key findings, activities, outcomes, and innovations from the research conducted. - Evaluate technical information and determine its relevance and significance. - Consolidate information from multiple sources into a cohesive narrative. - Prepare comprehensive annual technical reports that accurately summarise research activities undertaken during the previous financial year. - Ensure all reports are professionally written, logically structured, and technically accurate. - Collaborate with internal stakeholders when clarification or additional context is required. Qualifications - Strong technical aptitude with the ability to understand and interpret complex technical information. - Experience working with technical documentation, research reports, IT systems, engineering documentation, software development projects, or similar technical environments. - Ability to quickly grasp unfamiliar technical concepts and terminology. - Excellent written English skills. - Proven ability to produce clear, concise, and professional technical reports. - Strong attention to detail, grammar, and document quality. - Ability to present complex information in a way that is easily understood by a range of audiences. - Strong critical thinking and analytical abilities. - Ability to identify key themes, trends, and outcomes from large volumes of information. - Experience synthesising information from multiple sources into a structured report. Ideal Candidate The ideal candidate combines strong technical understanding with exceptional writing ability. They enjoy analysing information, identifying key insights, and producing high-quality reports that accurately reflect complex research activities. Benefits - Remote working environment - Opportunity to work with a diverse range of technical projects and industries - Supportive team culture - Professional growth opportunities