Associate Director, Inflammation Biology
Location
Massachusetts
Posted
16 days ago
Salary
$185K - $205K / year
Seniority
Senior
Job Description
Associate Director, Inflammation Biology
Apogee Therapeutics
• Apply deep expertise in biology and pharmacology to provide strategic scientific vision and guide therapeutic I&I biology research across atopic dermatitis, allergic asthma, EoE, and other I&I indications. • Design, develop, and oversee disease-relevant and complex in vitro and ex vivo models using multiple primary human cell types to evaluate the mechanism of action of Apogee antibodies and target biology. • Contribute to authoring and reviewing regulatory submissions and publications. • Manage and coordinate projects (in-house & CRO) to ensure adherence to timelines and goals. • Establish and promote laboratory best practices. • Analyze and interpret complex data from studies to inform on program decisions and effectively communicate outcomes and recommendations to the research group and senior leaders. • Collaborate with scientists across functions to generate high-quality data supporting programs from discovery through development.
Job Requirements
- Ph.D. degree and a minimum of 8 years of scientific/technical experience.
- Broad understanding of I&I disease biology (atopic dermatitis, asthma, and EoE) and underlying disease mechanisms is required and familiarity with inflammatory cytokine/chemokine networks is strongly preferred.
- Hands-on expertise developing and validating complex in vitro and ex vivo functional models using disease relevant cell types
- Proficiency with analysis of large, cross-platform data sets and assay platforms such as ELISA/MSD, flow cytometry, and cytokine/mediator release assays to characterize and advance therapeutic antibodies and target biology.
- Ability to manage multiple projects with competing timelines and shifting priorities simultaneously.
- CRO management experience including evaluation of new CROs is desired.
- Experience managing and developing junior scientists.
Benefits
- A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
- Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
- Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
- We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
- Commitment to growing you professionally and providing access to resources to further your development
- Apogee offers regular all team, in-person meetings to build relationships and problem solve
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