Director, US Commercial REMS Lead Location: Remote - US Job Code2464 # of openings1 Director, US Commercial REMS Lead Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. The impact you will make: The Director, US Commercial REMS Lead drives US Commercial strategies, activities, and insight gathering related to REMS (Risk Evaluation and Mitigation Strategies). The Director leads the development, implementation, and ongoing management of commercial related REMS activities to support compliance, patient safety, and effective execution across sales, field marketing, patient support, specialty distribution and other customer-facing teams. This role requires partnership with Commercial, Safety, Regulatory, Patient Services, and external vendors to translate REMS requirements into clear strategies, aligned tactics, and measurable outcomes. What you will do: - Serve as the primary Commercial liaison on REMS topics across internal stakeholders and external partners. Attend select Governance and REMS core team meetings. - Lead US Commercial strategy, operations, and insight generation across Agios products/indications with a REMS. - Partner with Sales, Marketing, Commercial Training, Patient Services, Safety, Quality Assurance and Regulatory teams to align strategy, communications, and execution. - Lead the Commercial implementation of new REMS programs/modifications and ongoing compliance activities. - Participate in cross-functional workstreams to implement initiatives that improve REMS effectiveness and ensure ongoing success of the program. - Support the development of Commercial REMS training, communication, and materials that enable effective REMS understanding and pull-through. - Use multiple data sources to generate Commercial insights, refine strategy, and strengthen operational performance. - Partner with Commercial Operations and Analytics to design, track, and present key commercial REMS related metrics and KPIs to leadership. - Foster strong collaboration and accountability across internal teams and external partners. What you bring: - Bachelor’s degree in a scientific or business discipline. - 10+ years of experience in biotechnology or a related industry. - Demonstrated REMS experience within a Commercial environment. - Strong record of high performance in operational and cross-functional roles. - Experience leading large, complex, cross-functional initiatives. - Excellent communication skills and the ability to build strong partnerships. - Strong understanding of compliance requirements and guidance governing REMS programs. - High learning agility, sound judgment, and strong people skills. - Experience leading people, projects, or both. - MBA or other advanced degree preferred. - Experience in rare disease preferred. Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $183,549 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Title: Senior Director, Engineering DT - Defense Engineering Location: Detroit United States Job Description: Job Description Summary In January of 2026, a new organization was created in GE Aerospace called Engineering and Future of Flight which integrates processes and teams across Engineering, Quality, Supply Chain, and Manufacturing. As part of that organization a team was created focused on the Engineering processes, digital products, and tools. The Senior Director, Engineering DT - Defense Engineering role, will be a strategic role in the Engineering and Future of Flight DT organization, reporting to the Engineering and Future of Flight CIO, and will be responsible for owning & operating organization-wide technology platforms, and ensuring stable operations. - Remote candidates will be considered Need to be able to travel as needed Job Description In this role you will: - Act as a thought leader leading multiple technology programs in Engineering and Future of Flight DT organization for Defense Engineering teams - Play a key role in supporting the unique engineering needs of the Defense business across both Defense Engines & Services (DES) and Edison Works. - Partner/collaborate across GE Aerospace to influence an GE Aerospace wide MBE strategy that serves both our defense and commercial businesses. - Explore and define AI applications within Engineering processes, digital products, and tools. - Act as primary liaison between the Defense Engineering organization and Engineering and Future of Flight DT Engineering. - Communicate effectively to engage, inform & influence business stakeholders as well as DT teams. - Establish and facilitate processes for decision making, process flows and handoffs. - Recruit and develop world-class global technical talent in Engineering and Future of Flight Engineering DT organization. - Ensure stable and secure operations across the Engineering and Future of Flight technology landscape. - Heavy cross functional influencing around a single vision as well as operating and engaging multiple levels within the organization. - Act as a practitioner and coach of FLIGHT DECK, GE Aerospace's proprietary Lean Operating System, to accelerate the deployment of strategic capabilities and value to the business, and to drive standard work in the way in which critical data & technology outcomes are designed, delivered, and supported. Required Qualifications: - Bachelor's degree from accredited university or college with minimum of 10 years of professional experience OR associate's degree with minimum of 13 years of professional experience OR High School Diploma with minimum of 15 years of professional experience - Minimum 7 years of professional experience in a variety of IT functional and leadership roles - Minimum of 5 years of professional experience as a People Leader - Note: Military experience is equivalent to professional experience - Legal authorization to work in the U.S. is required. We will not sponsor individuals for employment visas, now or in the future, for this job. This role requires access to U.S. export-controlled information. Therefore, employment will be contingent upon the ability to prove that you meet the status of a U.S. Person as one of the following: U.S. lawful permanent resident, U.S. Citizen, have been granted asylee or refugee status (i.e., a protected individual under the Immigration and Naturalization Act, 8 U.S.C. 1324b(a)(3)). Additional Information GE Aerospace offers a great work environment, professional development, challenging careers, and competitive compensation. GE Aerospace is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, religion, national or ethnic origin, sex, sexual orientation, gender identity or expression, age, disability, protected veteran status or other characteristics protected by law. GE Aerospace will only employ those who are legally authorized to work in the United States for this opening. Any offer of employment is conditioned upon the successful completion of a drug screen (as applicable). Relocation Assistance Provided: Yes

Title: Senior Director, Head of US Regulatory Affairs Policy & Intelligence Location: Washington, United States, Washington, 20001 Job Id: 67756 We Are Teva We’re Teva, a leading innovative biopharmaceutical company, enabled by a world-class generics business. Whether it’s innovating in the fields of neuroscience and immunology or delivering high-quality medicine worldwide, we’re dedicated to addressing patients’ needs now and in the future. Here, you will be part of a high-performing, inclusive culture that values fresh thinking and collaboration. You'll have the room to grow, the flexibility to balance life with work, and the opportunity to better health worldwide, together. Our Team, Your Impact Remote with frequent travel to the Washington DC area. This role combines senior‑level regulatory policy leadership, regulatory intelligence, and external advocacy, with accountability for shaping US regulatory outcomes, enabling development and portfolio strategy, and strengthening Teva’s influence and credibility with FDA and key stakeholders. The Head of US Regulatory Policy & Intelligence is responsible for defining and executing Teva’s US regulatory policy and intelligence strategy to enable timely patient access to medicines and support Teva’s generics, biosimilars, and innovative medicines portfolios. This role serves as Teva’s senior US regulatory policy lead, shapes policy positions, guides advocacy strategy, and provides timely actionable regulatory intelligence across FDA, Congress, and external stakeholders to Teva’s cross-functional leaders. This role has significant decision‑making authority and influence, requiring advanced regulatory judgment, strategic problem‑solving, and the ability to shape US regulatory policy outcomes in alignment with Teva’s business objectives and public health priorities. The role is accountable for strengthening Teva’s credibility and policy influence across FDA and key US stakeholder forums. US Regulatory Policy Strategy & Leadership - Lead the development and delivery of Teva’s US regulatory policy strategy across generics, biosimilars, and innovative medicines, aligned with enterprise priorities and portfolio needs. - Translate evolving FDA, congressional, and administration priorities into clear internal guidance and action plans. - Serve as the primary US policy advisor to Global Regulatory Affairs, R&D, and enterprise leaders. - Drive Teva’s US regulatory policy agenda, identifying opportunities for proactive advocacy and engagement. - Create and advance policy positions through agency engagement, trade association leadership, public comments, white papers, and advocacy initiatives. - Leverage trade associations and multi‑stakeholder forums to amplify Teva’s policy positions and influence regulatory outcomes How You’ll Spend Your Day External Engagement & User Fee Programs - Lead Teva’s US FDA policy engagement, including senior‑level interactions with FDA leadership on regulatory frameworks, policy interpretation, and program design. - Own Teva’s strategy and positioning for US FDA user fee programs (PDUFA, GDUFA, BsUFA), including negotiations, intelligence, implementation oversight, and internal capability building. - Drive policy solutions to address regulatory issues, review delays, and procedural barriers impacting product approvals. - Oversee internal implementation of FDA user fee commitments in partnership with R&D, Regulatory Affairs, and other stakeholders. - Develop and maintain relationships with FDA leadership, other key global health authorities, trade associations, and pharmaceutical industry counterparts. - Coordinate with Global and EU Regulatory Policy & Intelligence leads to ensure consistency of policy positions and alignment across regions. Regulatory Intelligence - Oversee US regulatory intelligence activities, including monitoring and analysis of guidances, RFIs, legislation, enforcement trends, and policy signals. - Ensure timely, high‑quality intelligence dissemination through alerts, briefings, written analyses, and leadership updates. - Anticipate policy risks and opportunities associated with changes in FDA leadership, administration priorities, and legislative cycles. - Establish, lead, and continuously improve structured regulatory intelligence forums, including recurring briefings and targeted policy deep dives. - Analyze regulatory and legislative developments to identify business, development, and portfolio impacts, affected stakeholders, and required actions. - Coordinate cross‑functional response strategies to policy developments, ensuring consistent internal and external messaging. Trade Associations & External Advocacy - Represent Teva in US and global trade associations, shaping industry positions and coordinated advocacy strategies. - Lead development and submission/socialization of Teva comment letters, white papers, briefing memos, and external policy positions. - Engage with Members of Congress and congressional staff in partnership with Government Affairs, and executive branch officials to advance Teva’s regulatory policy objectives. Cross‑Functional Partnership & Enablement - Partner with Regulatory Affairs, R&D, Quality, Manufacturing, Legal, Government Affairs, Operations, and Communications to align policy strategy with development, supply, and commercialization priorities. - Provide policy input for senior-level FDA engagements, congressional engagements, and external presentations. - Support portfolio-specific and enterprise-wide initiatives requiring US regulatory policy expertise, including innovation, development strategy, and external positioning. - Develop and execute coordinated regulatory policy and advocacy strategies, ensuring aligned messaging. Team Leadership & Global Alignment - Lead and develop US Regulatory Policy & Intelligence activities, setting clear priorities, objectives, and development pathways. - Contribute to the broader Policy & Intelligence team and global policy strategy. - Lead, mentor, and develop team members, fostering high standards for analytical rigor, written advocacy, and executive communication. - Establish clear objectives, operating models, and quality standards. Your Skills and Experience Required - Advanced degree (MS, PhD, JD, MPH, or equivalent) in a scientific, regulatory, or policy‑related discipline. - Minimum 12–15 years of experience in US regulatory affairs, regulatory policy, or health policy, including substantial FDA engagement. - Deep expertise in US regulatory frameworks, FDA programs, and the Food, Drug, & Cosmetic (FD&C) Act, the Public Health Service (PHS) Act, and FDA user fee legislation (e.g., PDUFA, GDUFA, BsUFA). - Demonstrated experience leading policy development, advocacy, and regulatory intelligence activities. - Proven ability to engage credibly with FDA leadership, industry associations, and government stakeholders. Also Good to Have Preferred - Prior FDA experience strongly preferred. - Experience representing companies within trade associations and multi‑stakeholder policy forums. - Strong executive communication skills, including briefing senior leadership and authoring high‑impact policy materials. Salary Range The annual starting salary for this position is between $248,000 – $310,000 annually. Factors which may affect starting salary within this range and level of role may include geography/market, skills, education, experience and other qualifications of the successful candidate. How We’ll Take Care of You We offer a competitive benefits package, including: - Comprehensive Health Insurance: Medical, Dental, Vision, and Prescription coverage starting on the first day of employment, providing the employee enrolls. - Retirement Savings: 401(k) with employer match, up to 6% and an annual 3.75% Defined Contribution to the 401k plan. - Time Off: Paid Time Off including vacation, sick/safe time, caretaker time and holidays. - Life and Disability Protection: Company paid Life and Disability insurance. - Additional benefits include, but are not limited to, Employee Assistance Program, Employee Stock Purchase Plan, Tuition Assistance, Flexible Spending Accounts, Health Savings Account, Life Style Spending Account, Volunteer Time Off, Paid Parental Leave, if eligible , Family Building Benefits, Virtual Physical Therapy, Accident, Critical Illness and Hospital Indemnity Insurances, Identity Theft Protection, Legal Plan, Voluntary Life Insurance and Long Term Disability and more.  The total compensation may also include restricted stock units and discretionary awards, depending on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment.   Teva’s Equal Employment Opportunity Commitment Teva Pharmaceuticals is committed to equal opportunity in employment. It is Teva's policy that equal employment opportunity be provided without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, genetic information, marital status, sexual orientation, gender identity or expression, ancestry, national or ethnic origin, citizenship status, military status or status as a disabled or protected veteran, or any legally recognized status entitled to protection under applicable federal, state, or local laws.    Please advise us of any accommodations needed to support you throughout the recruitment and selection process. All accommodation information provided will be treated as confidential and used only for the purpose of providing an accessible candidate experience. Request a reasonable accommodation by sending an email to AskHR@tevapharm.com with the nature of your request and your contact information. Only inquiries concerning a request for a reasonable accommodation will be responded to from this email address.   Important notice to Employment Agencies - Please Read Carefully   Teva Pharmaceuticals USA does not accept unsolicited assistance from agencies for employment opportunities.  All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Title: Director of Hotel Technology Location: Philadelphia, PA Job Description: Opportunity: Director of Hotel Technology HHM Hotels is an industry-leading hotel investment, management and development firm that provides turn-key management solutions to over 230 hotels across the United States, which includes world class brands (Hilton, Marriott, Hyatt, and IHG) in the select service and full-service markets as well as a collection of over 30 independent and boutique hotels. HHM Hotels is seeking a Director of Hotel Technology to oversee portfolio-wide support for guest-facing technology, telecommunications, and guest satisfaction (GSS) improvements, and act as a liaison with outside vendors and the operations team. Further, this individual will direct IT support for nearly 3,000 end users in hotels, corporate offices, and regionally located leaders. This position can be remote-based in the Northeast US, or out of our corporate offices in Harrisburg, PA or Philadelphia, PA. Your Growth Path Vice President of Hotel Technology – Vice President of Information Technology – Head of IT Your Focus Leadership: - Partner with Regional Operations, Hotel Leadership, and Corporate Teams to execute enterprise technology initiatives aligned with operational goals, guest experience, and business priorities. - Maintain awareness of emerging technologies and industry trends to support innovation and continuous improvement across the portfolio. - Develop and lead a high-performing team with strong technical expertise, operational knowledge, and service orientation. Execution and Oversite: - Lead portfolio-wide hotel technology projects from planning through execution, including scope, timelines, stakeholders, budgets, risks, and deliverables. - Partner with IT teams and property leadership to coordinate system implementations, upgrades, support strategies, and operational priorities across the portfolio. Service Delivery with 3rd Parties: - Oversee deployment, administration, and ongoing support for infrastructure, hotel operational systems, end-user technology, and guest-facing platforms. - Partner with vendors and IT teams to support business continuity, asset management, training, documentation, and knowledge transfer across the portfolio. Operational Effectiveness: - Collaborate with IT Teams to Identify and implement operational and service improvement metrics, SLA’s and support processes necessary to ensure service performance, scalability, reliability and uptime - Liaison with Corporate Human Resources, Operations and Training teams to maintain current knowledge of training and develop tools and systems, operational systems best practices and company policies and procedures - Develop and maintain relationships with Vendors, 3rd Party Business Partners and Service Providers. Ensure service providers perform to contractual SLAs and service obligations Financial & Governance: - Support IT financial planning, governance, security, compliance, and change management processes in alignment with enterprise standards and operational objectives. Your Background & Skills - 5+ years of technology leadership experience, preferably within hospitality or a multi-unit environment - Strong operational and technical understanding of hotel technology systems and support functions - Proven ability to manage multiple priorities, navigate complex challenges, and drive projects to completion in a fast-paced environment - Strong communication, collaboration, and stakeholder management skills - Bachelor’s degree in technology, business, accounting, or a related field preferred - Ability to travel to properties as needed HHM Hotels Benefits and Perks - Competitive wages for full time and part time opportunities - Medical, Dental and Vision Health Insurance - Paid Time Off - 401k Company Match - Free Basic Life Insurance - Travel Discounts - Commuter Transit and Commuter Parking Benefits - 24/7 access to TELUS Health, a confidential work-life resource. - Educational/Professional Development - Referral Bonus Program Work Environment and Context - Work schedule varies and may include working on holidays, weekends and alternate shifts. - Requires standing for extended periods, walking, pushing, lifting up to 50 pounds, bending and reaching. What We Believe People Are Our Capability – Hearts That Serve – Only Excellence – Stay Nimble - Own It