Role Description As the Director/Senior Director, Program Leadership, you will own the operations and execution of advancing assets through IND-enabling studies, CMC, and regulatory submission across multiple programs. You will play a central role in moving programs efficiently toward the clinic while helping shape how program leadership operates and scales within the company. Reporting to the Chief Operating Officer, you will bring deep experience in preclinical program leadership, strong strategic and operational judgment, and clear communication to ensure programs progress effectively across complex, interdependent workstreams. Location: Remote What You’ll Do - Own the full program lifecycle from candidate nomination through IND clearance and Phase 1 enablement across multiple assets in parallel - Drive the critical path, including timelines, budgets, dependencies, and decision points - Build and maintain integrated development plans spanning nonclinical, CMC, analytical, formulation, and regulatory workstreams - Translate program progress into clear, actionable updates and recommendations for leadership - Own external partnerships with CROs and CDMOs, including vendor selection, scope definition, and ongoing performance management - Negotiate scope, cost, timelines, and deliverables and hold partners accountable to outcomes - Coordinate across multiple vendors simultaneously, managing handoffs, data flow, and interdependencies - Partner with internal technical experts to design studies and translate program needs into effective external workstreams - Oversee development of study protocols, incorporating cross-functional input and aligning stakeholders - Build the internal playbooks, processes, and operating structures needed to scale program execution across the pipeline Qualifications - Direct operational ownership of multiple IND programs in biologics, with at least one specifically in functional protein therapeutics - Advanced degree in biochemical, pharmacology, toxicology or related field such as biology and life sciences - 8+ years (Ph.D.) to 12+ years (Master’s) of relevant industry experience - Demonstrated success leading programs through CROs and CDMOs, including global vendors - Deep understanding of the drug development process from discovery through IND filing - Strong familiarity with GxP, ICH guidelines, and FDA preclinical requirements - Proven ability to align and influence stakeholders across functions and organizations Requirements - Strong strategic and operational judgment - Clear, concise communicator who can simplify complex programs - Highly organized and detail-oriented, with the ability to anticipate challenges - Hands-on leader who is comfortable owning outcomes directly - Effective at influencing without formal authority - Comfortable operating in a fast-moving, evolving environment Benefits - Opportunity to drive multiple programs from early development through IND and into the clinic in a highly integrated, fast-moving environment - Ability to work at the intersection of AI, biology, and experimental science on problems where the path forward is not always clear - Significant ownership and influence on how programs are executed, prioritized, and scaled as the pipeline grows - Exposure to both strategic decisions and hands-on execution in a lean team where your work directly impacts program outcomes Additional Information Compensation Range: $175,000 - $250,000. Individual compensation within this range is determined by a combination of factors, including but not limited to level, years of relevant job-related experience, and internal equity. This is what we believe in good faith is the range of possible base salary for this role at the time of this posting. We may ultimately pay more or less than the posted range. This range may be modified in the future.

• Own clinical quality strategy for a rapidly scaling network spanning 20+ states, 400+ clinicians, and multiple care models. • Design and operationalize frameworks for performance monitoring, documentation standards, and audit readiness that are built to scale — not patched as the organization grows. • Translate regulatory requirements into practical workflows. • Present quality trends, risk signals, and improvement recommendations to the extended leadership team alongside peers in Clinical, Operations, and Product. • Inform board-level reporting on clinical risk and compliance posture. • Define what effective, evidenced based clinical supervision looks like at Cartwheel and build the systems to measure and develop it. • Own HIPAA compliance, incident management, complaint and grievance workflows, and payer audit readiness across all operating jurisdictions. • Build clinical compliance policy infrastructure that anticipates growth rather than reacts to it. • Set the performance standard for Cartwheel's clinician network — not just identify when it's missed. • Lead and develop a team that grows with the organization.

Role Description Schulte Hospitality Group is seeking a dynamic, service-oriented Regional Director of Revenue Management to join our team! - Grow RevPAR and RevPAR Index. - Daily room inventory management. - Monitor hotel and competitor rates, availability, strategies, and seasonality and adjust pricing accordingly. - Review unconstrained demand and provide recommendations for the optimal mix of business. - Establish target pricing for Group and Transient and by segment. - Analyze local events and project their impact. - Prepare weekly and monthly forecasts. - Conduct displacement analysis with group or contract. Monitor online reviews. - Review STR reports and provide analysis of hotel performance against their comp set. - Review additional tools such as Hotelligence or Demand Positioning reports. - Assist with the preparation of the annual rooms revenue budget and business plans. - Ensure distribution channels have accurate content and pricing. - Develop relationships with the Online Travel Agencies (OTA) or Third Party Intermediaries (TPI) to maximize opportunities through these channels. - Assist with internet marketing campaigns, GDS advertising, etc. - Assist in developing the hotel managers so that they become proficient with revenue management. - Review prior days results and opportunities e.g. did the hotel sell out? Did overbooking have the desired effect? Did the hotel have the desired mix of business? - Monitor group blocks and cut off dates. - Work with the hotel to ensure coding and tracking is performed correctly. - Review production of negotiated accounts with hotel's sales leader. - Perform various other duties as assigned to meet business objectives. Qualifications - Minimum of two (2) years revenue management experience. - Experience with hotel sales software. Requirements - Exceptional service and customer relations skills with ability to foster effective relationships with staff, management and clientele. - Excellent verbal and written communication skills and ability to communicate ideas and concepts. - Highly proficient in computers including, but not limited to Internet, Microsoft Office programs and hotel sales related programs. - Strong facilitation and presentation skills. Benefits - Work Today, Get Paid today, with Daily Pay! - Free Telemedicine and Virtual Mental Health care access for All Associates starting day one! - Multiple Health Insurance and Life Insurance options. - 401k Plan + Company Match. - Paid Parental Leave. - Paid Time Off. - Holiday Pay. - Pet Insurance. - Employee Assistance Program. - Schulte Savings Marketplace Discounts on event tickets, electronics, gym memberships + more! Company Description Schulte Hospitality Group is a leading third-party management company with deep, multi-generational experience in all facets of the hospitality industry. We are a diverse team of innovative hoteliers and restauranteurs operating more than 200 locations across 38 states and 3 countries. Our portfolio includes a wide array of reputable brands like Marriott, Hilton, IHG and Hyatt as well as many unique, independent, boutique and lifestyle properties and restaurants.

Title: Global Safety Lead Location: Remote United Kingdom Full time Remote Join us as a Medical Director M-SERM - And lead our efforts in medical safety evaluation and risk management. What You’ll Do: • Maintain understanding of methods for recording time spent on project and administrative tasks, expense submissions and travel. • Ensure tasks delegated to PV are properly executed. Adhere to applicable regulations and ICH guidelines regarding clinical trials, regulatory documents, and safety issues. Adhere to client SOPs/directives and project specific WPDs for assigned projects. Adhere to CRG’s corporate policies and SOPs/WPDs. • Provide medical consultation to team members and answer all project/study related medical questions. Communicate clearly with associates and clients, maintaining an open line of communication to ensure all procedures are followed appropriately. • Provide safety reporting training on assigned projects/studies, as requested. • Medically reviews adverse events and serious adverse event data from all sources (solicited, spontaneous, literature, etc) as contracted. • Provide medical review of adverse events of special interest, serious adverse events and clinical outcomes events reported in Clinical Trials. • Perform data review as specified in the client contract and data validation manual including review of coding listings and/or full safety data to assess for potential safety concerns. • Assist in writing (interpretation of safety data) and/or review of CSR, IND/NDA report, ICSR, signal detection reports, periodic reports, RMP, REMS, CTD modules, etc. to ensure that the medical content is accurate and complete. • Manage signal detection activities, scientifically review periodic safety reports, contributes to label updates, supports dossier maintenance and risk management activities. Education and Experience: MD or equivalent required. History of an active medical license is highly preferred. Candidates should have at least one of the following: • Clinical experience in having direct responsibility for diagnostic and treatment decisions (comparable to 2 years); Or • Direct experience in medical review and assessment of safety information/Pharmacovigilance (comparable to 3 years). In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role. Knowledge, Skills and Abilities: • Fluent in spoken and written English • General medical knowledge of diagnostic and therapeutic approaches across multiple specialties. Therapeutic expertise across one or more medical specialties or sub-specialties preferred • Strong decision-making, problem solving, organizational skills and analytical skills • Excellent oral and written communication skills • Excellent interpersonal skills • Working knowledge of guidelines (FDA, ICH, EMA and GCP) • Understanding of basic biostatistics, data management, and clinical operations procedures • Excellent organizational skills • Ability to work independently, analyze work with attention to detail, process and prioritize sensitive complex information • Working knowledge of the drug development process and thorough understanding of guidelines for marketing authorization submissions and international guidelines for conduct of clinical studies • Working knowledge of clinical program and study design, relevant endpoints, safety considerations, and current regulatory and commercial landscape. • Working knowledge of marketed products pharmacovigilance regulations • Working knowledge of Drug Safety Dictionaries (e.g. MedDRA) • Working knowledge of relevant safety databases (e.g. ARGUS, ARISg) • Ability to act as a mentor/trainer to entry level staff within the Pharmacovigilance Department • Flexibility to travel domestically and internationally • Proficiency in basic computer applications • Ability to serve as a group liaison with other CRG groups and clients