Title: Associate Director, Biologics Manufacturing Management Location: Bedford, MA; Woburn, MA; or Somerville, MA Job Description: Why Join Us? Be a hero for our rare disease patients At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them. Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work. If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team. Position Summary: ultrainnovative – Tackle rare and dynamic challenges You will provide technical expertise for critical starting materials, drug substance, and/or drug product manufacturing over the life cycle of the products in the Ultragenyx biologics/gene therapy portfolio from development through commercialization. You will serve as external manufacturing relationship manager at the respective contract manufacturing organizations (CMOs) and represent manufacturing as part of cross-functional Ultragenyx CMC teams. Work Model: Flex: This role will typically require onsite work 2-3 days each week, or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite. Responsibilities: - Oversee external manufacturing of plasmid DNA, biologics and gene therapy drug substance, as well as aseptic drug product manufacturing for biologics and oligonucleotides. - Ensure fulfillment of agreed manufacturing services at CMOs for clinical and commercial supply plans. - Lead relationships with CMOs and foster collaborative partnership. - Participate in Health Authority interactions as a subject matter expert. - Author global CMC filings in accordance with applicable regulations and guidance. - Identify and enable selection of DS and DP CMOs, ensure CMO compliance to cGMPs and establish strategic fit. - Actively identify and manage product or manufacturing process risks. - Manage process optimization, tech transfer, and change control. - Drive troubleshooting and quality deviation investigations occurring at manufacturing sites. - Direct key business agreements, manage budget & cost control, approve purchase orders & invoices, and improve COGS development. Requirements: - BS in Pharmaceutical, Biological or Bioengineering Sciences or Engineering. - 10+ years of relevant combined experience in Process Development, MSAT, Quality Assurance, or Manufacturing in biotech / pharmaceutical industry. Fewer years are acceptable if combined with relevant advanced degree. - Technical experience in process development and commercial bioprocess manufacturing, including one or more of plasmid DNA, enzymes, antibodies, gene therapies, or aseptic drug product manufacturing. - Substantial experience working in an outsourcing model, involving CMO/CDMO management. - Proficient in cGMPs and pharmaceutical industry procedures and regulations. - Good understanding of financial figures, cost management and financial decision making. - Strong collaboration, communication skills and drive for results. - Excellent problem-solving skills and verbal/written communication skills. - Ability to support work requirements across multiple Ultragenyx time zones and reflective of 24/7 manufacturing schedules at CMO sites, as applicable. - Up to 25% travel commitments (domestic and international) and occasional person-in-plant activities. LI-C1 #LI-Hybrid The typical annual salary range for this full-time position is listed below. This range reflects the characteristics of the job, such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicant's geographic location. This position is eligible for annual bonus and equity incentives. Actual individual pay is determined by demonstrated experience and internal equity alignment. Pay Range $179,300—$221,400 USD Full Time employees across the globe enjoy a range of benefits, including, but not limited to: · Generous vacation time and public holidays observed by the company · Volunteer days · Long term incentive and Employee stock purchase plans or equivalent offerings · Employee wellbeing benefits · Fitness reimbursement · Tuition sponsoring · Professional development plans Benefits vary by region and country Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com. See our CCPA Employee and Applicant Privacy Notice. See our Privacy Policy. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to: talentacquisition@ultragenyx.com.

Role Description The Opportunity We’re hiring an Executive Creative Director, Digital Experience to define and elevate the creative direction of our global digital ecosystem. This role will shape how our website and owned digital experiences express our brand, product strategy, and innovation. Sitting at the intersection of storytelling, interaction, and system design, you will define what exceptional looks like across product, solutions, and educational experiences—ensuring our digital presence is as compelling as the technology behind it. As AI reshapes how people discover, evaluate, and engage with products, this leader will help reimagine how modern digital experiences should look, feel, and evolve. What You’ll Do - Define Creative Direction for Digital Experience - Articulate a bold, future-oriented creative vision for our website and owned digital platforms. - Reimagine how product and solution experiences come to life online—balancing clarity, inspiration, and performance. - Shape how storytelling, interaction, and modular systems work together across a growing portfolio. - Anticipate the impact of AI, LLM-driven discovery, and evolving digital behaviors on experience design. - Elevate Craft and Experience Quality - Raise the bar for design excellence, interaction, and digital storytelling. - Guide the evolution of layout systems, motion, content models, and expressive frameworks that scale. - Establish a clear creative quality standard across digital touchpoints. - Champion thoughtful, modern approaches to web design that differentiate us in the market. - Partner Across the Organization - Collaborate closely with Brand, Product Marketing, Product Design, Growth, and Engineering to ensure cohesive and impactful experiences. - Serve as a creative bridge between brand expression and product truth within digital environments. - Influence senior stakeholders and contribute to executive-level conversations about the future of digital experience. - Innovate for a Digital-First World - Think in systems, flows, and adaptive moments—not just pages. - Explore new tools, technologies, and production models that enhance creative capability. - Contribute to the long-term evolution of how digital experiences perform and mature. Qualifications - 15+ years of experience leading digital creative direction at scale—within product-led companies, agencies, or global brands. - A portfolio demonstrating exceptional craft, systems thinking, and strategic storytelling across complex digital ecosystems. - Deep fluency in modern web design, UX principles, modular systems, and digital platforms. - Experience partnering across cross-functional teams in matrixed environments. - Strong executive presence with the ability to clearly articulate and advocate for creative direction. - A sharp eye for detail and an uncompromising bar for quality. - Curiosity about emerging technologies, AI-driven behaviors, and evolving digital platforms. Additional Information - Work Personas - We approach our distributed world of work with flexibility and trust. Work personas (flexible, remote, or required in office) are categories that are assigned to ServiceNow employees depending on the nature of their work and their assigned work location. - Equal Opportunity Employer - ServiceNow is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, sex, sexual orientation, national origin or nationality, ancestry, age, disability, gender identity or expression, marital status, veteran status, or any other category protected by law. - Accommodations - We strive to create an accessible and inclusive experience for all candidates. If you require a reasonable accommodation to complete any part of the application process, or are unable to use this online application and need an alternative method to apply, please contact [email protected] for assistance. - Export Control Regulations - For positions requiring access to controlled technology subject to export control regulations, including the U.S. Export Administration Regulations (EAR), ServiceNow may be required to obtain export control approval from government authorities for certain individuals. Employee Information - Employee Type: Regular - Region: AMS - North America and Canada - Work Persona: Flexible or Remote

• Lead and manage a team of Spend Managers overseeing and guiding their activities • Drive action and optimize the national and/or commit group purchasing organization by implementing strategies • Collaborate with Spend Executives and other organization executives to ensure support alignment • Ensure implementation of strategic programs by Spend Managers • Coach team on Quarterly Business Review contributions • Conduct skills practice with Spend Managers • Participate in performance improvement initiatives • Bring forward ideas for improvements related to standard work and automation • Oversee the direction and implementation of standard work • Provide key contributions to training curriculum

Role Description The Key Accounts Director is a senior sales leadership role responsible for managing and growing Tosoh Quartz Inc.’s most strategically important customer relationships. This role represents an evolution of the Key Account Manager position, with expanded accountability for account strategy, cross-account support, and internal leadership. The Key Accounts Director will act as the primary owner for Intel and oversee other major accounts, while also supporting broader key account development across the organization. This role serves as a critical bridge between executive leadership and account teams, ensuring consistent, strategic, and high-quality customer engagement. This position reports to the Vice-President of Sales and is a key component of TQI’s long-term leadership pipeline. Key Responsibilities - Strategic Account Leadership - Own and lead Tosoh Quartz Inc.’s most critical accounts - Develop long-term account strategies aligned with customer roadmaps and company capabilities - Serve as the executive-level point of contact for key customer stakeholders - Revenue Growth & Account Development - Identify and execute opportunities for revenue expansion within key accounts - Lead commercial negotiations, contract renewals, and strategic positioning - Maintain strong focus on priority accounts while delivering measurable growth - Cross-Account Support & Influence - Provide hands-on support and guidance to other Account Managers across key accounts - Leverage industry relationships to strengthen broader account performance - Contribute to complex or high-value customer engagements beyond primary account responsibility - Team Leadership & Mentorship - Mentor and develop junior and mid-level account managers - Support development of internal sales capabilities, including communication and strategic account planning - Provide consistent domestic leadership to complement global sales activities - Executive Support & Business Leadership - Develop high-quality customer presentations, reports, and strategic materials - Translate account insights into executive-level summaries and recommendations - Reduce administrative and reporting burden at the VP level by owning mid-tier strategic work - Organizational Impact & Scaling - Support the evolution of the sales organization structure over time - Potentially assume leadership of additional Key Account Managers as the role expands - Establish best practices in account management and customer engagement Reporting Structure - Reports to: Vice President of Sales - Potential future direct reports: Key Account Managers and Account Representatives - Works cross-functionally with global sales leadership and internal stakeholders Qualifications - Required - 10+ years of semiconductor industry experience in key account management, strategic sales, or related roles - Proven success managing complex, high-value customer relationships - Strong executive presence and communication skills - Ability to operate both strategically and tactically - Preferred - Experience in semiconductor, advanced materials, or technical manufacturing environments - Background combining commercial and operational experience - Experience mentoring or leading account managers Key Success Factors - Ability to elevate the quality and consistency of customer engagement - Strong ownership mindset with a drive to expand scope and impact - Balance between deep account focus and broader organizational contribution - High level of polish in communication and customer-facing outputs Career Path & Growth Opportunity This role is positioned as a key leadership pipeline role within Tosoh Quartz Inc., with potential progression into Vice President or broader executive leadership positions over time. Additional Information - Remote role with domestic travel requirement - No immediate relocation required - Scope expected to expand based on business needs and individual performance