• Engage with Key Opinion Leaders (KOLs) across the Gamifant Immunology therapeutic areas. • Ensure that appropriate cross‑functional resources are coordinated to support scientific exchange, advocacy development, and compliant commercial collaboration. • Align with cross‑functional account plans and teams to orchestrate marketing and commercial resources for the top 10–15% of KOLs. • Identify, profile, cultivate, and maintain long‑term relationships with KOLs within the pHLH and MAS community. • Conduct compliant, on‑label discussions focused on product, disease state, and company topics in appropriate venues. • Execute approved KOL programs (e.g., disease‑state or product education) as directed by leadership. • Collaborate closely with field teams (MSLs, FRMs, CBDs) to ensure strategic and tactical alignment for each assigned KOL. • Plan and execute KOL executive encounters at local, regional, and national conferences, POAs, and other approved venues in partnership with MSLs and cross‑functional colleagues.

• The Thought Leader Liaison Director (TLLD) is a field‑based, non‑sales leadership role responsible for engaging with Key Opinion Leaders (KOLs) across the Gamifant Immunology therapeutic areas • Ensure that appropriate cross‑functional resources are coordinated to support scientific exchange, advocacy development, and compliant commercial collaboration • Align with cross‑functional account plans and teams to orchestrate marketing and commercial resources for the top 10–15% of KOLs • Identify, profile, cultivate, and maintain long‑term relationships with KOLs within the pHLH and MAS community • Conduct compliant, on‑label discussions focused on product, disease state, and company topics in appropriate venues • Execute approved KOL programs (e.g., disease‑state or product education) as directed by leadership • Collaborate closely with field teams (MSLs, FRMs, CBDs) to ensure strategic and tactical alignment for each assigned KOL • Plan and execute KOL executive encounters at local, regional, and national conferences, POAs, and other approved venues in partnership with MSLs and cross‑functional colleagues • Provide actionable insights to commercial leadership to inform strategy and execution • Support on‑label KOL advocate development by providing education using approved materials and presentations • Gather and relay KOL feedback on new pHLH and MAS franchise and brand‑related marketing strategies and materials, ensuring all requests and materials are approved by Legal, Compliance, and Regulatory. • Serve as the central point of contact for speaker logistics and scheduling, ensuring seamless cross‑functional communication.

• The Thought Leader Liaison Director (TLLD) is a field‑based, non‑sales leadership role responsible for engaging with Key Opinion Leaders (KOLs) across the Gamifant Immunology therapeutic areas. • The position ensures that appropriate cross‑functional resources are coordinated to support scientific exchange, advocacy development, and compliant commercial collaboration. • Align with cross‑functional account plans and teams to orchestrate marketing and commercial resources for the top 10–15% of KOLs. • Identify, profile, cultivate, and maintain long‑term relationships with KOLs within the pHLH and MAS community. • Conduct compliant, on‑label discussions focused on product, disease state, and company topics in appropriate venues. • Execute approved KOL programs (e.g., disease‑state or product education) as directed by leadership. • Collaborate closely with field teams (MSLs, FRMs, CBDs) to ensure strategic and tactical alignment for each assigned KOL. • Serve as the primary point of contact to resolve KOL commercial or marketing issues when directed by Gamifant Marketing leadership or Headquarters.

Director Observational Research remote type Remote locations United States - Remote time type Full time job requisition id R-244736 Career Category Clinical What you will do Let’s do this. Let’s change the world. In this vital role you will leads the company's strategic planning initiatives and oversees its operational performance, working with leaders across the organization to implement the strategic vision. Do you want an exciting position working with multiple teams to generate real-world evidence supporting a wide variety of business needs? The growing demand for real-world evidence (RWE) from regulatory and reimbursement authorities makes observational research a key component of drug development and commercialization. Amgen's Center for Observational Research (CfOR) is a global organization with an industry-leading analytical capability that generates RWE to support business needs across a product’s lifecycle. CfOR scientists partner with internal collaborators and industry experts to craft, conduct, interpret, and publish observational research that advises decision-making from the early development of a molecule to the design of clinical trials and the safety and efficacy of Amgen medicines. CfOR studies include but are not limited to evidence generation regarding the frequency and distribution of disease, the clinical burden of disease, the natural history or clinical course of the disease, the design of clinical trials, treatment cost, and utilization patterns, and the safety and efficiency of therapeutic interventions. Job Description Amgen is searching for a Director of Observational Research, who will lead an asset in the Oncology therapeutic area. A CfOR director is recognized as a strong scientific contributor and is a first or contributing author for papers in peer-reviewed journals or for internal reports that enhance the company’s mission. Working with the cross-functional teams, the Director will be responsible for establishing strategic direction, and providing technical and managerial leadership through: - Designing and executing studies to support evidence generation such as identifying appropriate patient populations, assessing disease burden and resource utilization, obtaining product registrations and label-expansions, meeting post-marketing requirements/commitments and product differentiation. - Finding opportunities to substitute for and/or complement interventional studies to reduce time and cost of drug development. - Influencing cross-functional stakeholders in the utilization and timing of non-interventional research to answer high-priority strategic business questions. - Leveraging real-world data and CfOR analytic approaches to inform high-value business decisions for multiple partners. - Tracking business and functional priorities and aligning resources for those priorities. - Contributing to the mission of the CfOR including progressing innovative epidemiological methods and analytical capabilities to support the CfOR’s leadership role within Amgen and the industry. - Effectively leading, developing and mentoring staff and teams. - Participating in initiatives to improve capabilities within the CfOR and providing input. - Supporting the development of product and CfOR strategies. - Developing and maintaining relationships with organizational leaders. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree and 4 years of scientific experience OR Master's degree and 7 years of scientific experience OR Bachelor's Degree and 9 years of scientific experience OR Associate’s degree and 10 years of scientific experience OR High school diploma / GED & 12 years of scientific experience Preferred Qualifications: •Doctorate in Epidemiology or other subject with high observational research content •Experience in the design, execution, and analysis of observational research studies within Pharmaceutical or Public Health setting •Experience in research to support drug development •Experience in observational research project planning and management •Excellent verbal and writing communication and interpersonal skills •Experience working in multi-disciplinary teams What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: - A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts - A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan - Stock-based long-term incentives - Award-winning time-off plans - Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Salary Range 202,250.70USD -273,633.30 USD