• Medical Lead for the Clinical Development Team (CDT) to deliver Phase 3 asthma and COPD studies • Provide medical leadership and oversight for late-stage clinical trials in asthma and COPD • Develop and refine clinical strategies and Target Product Profiles (TPPs) specific to asthma and COPD • Serve as key author of late-stage clinical protocols, aligned with regulatory requirements • Author clinical and scientific content for regulatory submissions (e.g., BLA, MAA) • Oversee study design, protocol development, data review, and safety monitoring • Perform medical monitoring for late-stage studies, ensuring patient safety, protocol compliance, and data integrity • Serve as a member of the Safety Management Team (SMT) • Collaborate cross-functionally with Clinical Operations, Regulatory, Biostatistics, and Pharmacovigilance • Serve as primary medical contact for clinical sites, investigators, and CROs • Interpret clinical trial data and contribute to study reports, regulatory filings, and publications • Represent Generate at internal and external scientific and medical meetings • Engage with external experts, advisory boards, and health authorities to support program goals

• The Regional Business Director will be directly responsible for the management and profitability of their territory and their Territory Business Managers (TBMs). • Coach and develop each TBM to achieve his/her maximum individual potential, resulting in the achievement of key performance results. • Provide leadership necessary to achieve sales goals for marketed products in a region. • Hold ultimate accountability for maintaining effective relationships with key customers in the region. • Develop and maintain relationships with key physician practices, hospitals/clinics, and patient advocacy organizations. • Act as an ambassador to provide insights to the larger organization and increase recognition as a leader in Rare Disease. • Ensure compliance with all Company, industry and government laws or guidelines regarding ethical standards. • Establish a high performing sales team to operate in line with SpringWorks’ sales model and standards. • Oversee the development and execution of strategic sales and account plans. • Monitor and understand sales trends and competitor activities within the area and nation. • Attend sales meetings, training programs and medical conventions as requested.

• The Regional Business Director will be directly responsible for the management and profitability of their territory and their Territory Business Managers (TBMs) including managing their performance and consistently providing quality feedback, coaching and development opportunities to set them up for success. • Provide leadership necessary to achieve sales goals for marketed products in a region. • Develop and maintain relationships with key physician practices, hospitals/clinics, and patient advocacy organizations. • Act as an ambassador to provide insights to the larger organization and increase recognition as a leader in Rare Disease. • Ensure compliance with all Company, industry and government laws or guidelines regarding ethical standards.

• You are an experienced product delivery leader who thrives in complex environments and knows how to turn strategy into execution. • You will own the delivery of product work across the Wellbeing platform by managing Product Owners and building a consistent, high-rigor delivery model. • You’ll be accountable for execution, PO performance, and team throughput, making sure strategy turns into high-quality product delivered with predictable cadence. • This is a delivery leadership role, not a strategy or vision role.