• Develop trusted relationships with qualified treatment centers (QTC’s), healthcare professionals and patient organizations • Supporting the QTC in Utrecht, The Netherland and coordinating patient’s treatment ensuring that it adheres to what is described in the Product Manual and facilitating the exchange of the related mandatory documentation with Orchard’s Supply Chain Team • In partnership with the Medical Director, engage disease experts via advisory boards and individual interactions to accelerate patient identification and diagnosis • Oversee the development of disease-related and product-related materials and their approval for use in the Benelux, in partnership with the Medical Director • Drive disease awareness and the identification of potential patient candidates for treatment with Libmeldy® and other Orchard gene therapies • Resolve issues of access to treatment by potential patient candidates to gene therapy, in collaboration with the Market Access function • Plan activities and track budget in the franchise • Role-model corporate values and behaviours; foster compliance with legal and regulatory requirements and corporate SOPs, and the pursuit of the highest ethical standards • Performs other tasks and assignments as needed and specified by management. regarding the strategy and operations in the neurometabolic franchise • Represent Orchard during meetings and congresses.

• Own the full lifecycle of government funding opportunities, including RFPs, tenders, grants, and alternative funding submissions • Lead narrative development, cross-functional coordination, submission, and quality control • Ensure all submissions are compliant, aligned to evaluation criteria, and delivered to a high standard under tight timelines • Act as the central orchestrator across US functions (Clinical, Legal, Finance, Product, Service Operations, Account Management) • Build and scale a high-quality, repeatable approach to procurement submissions • Develop and maintain templates, content libraries, and standardized workflows • Define clear win themes and positioning strategies for government buyers • Continuously improve submission quality through post-submission reviews and win/loss insights • Ensure consistency and scalability across US and UK markets • Strengthen how Kooth identifies and accesses funding pathways • Track and evaluate federal, state, and local funding opportunities, including grants and alternative funding streams • Monitor legislative and policy developments to anticipate market opportunities • Provide clear, actionable insights to Commercial Leadership on funding access and risks • Establish structured processes for tracking, prioritization, and coordinated response • Ensure funding strategy, service design, and commercial approach are aligned • Partner with Commercial Leadership on go/no-go decisions and bid strategy • Align funding requirements with service model design and commercial viability • Translate external funding dynamics into clear internal priorities and actions • Support a seamless transition from award to contract execution • Lead internal coordination from notice of award through contracting • Partner with Legal and Finance to ensure timely, accurate, and commercially aligned contracts • Track key requirements, deliverables, and dependencies • Enable a smooth handoff to implementation and account management • Drive clarity and accountability across complex, high-stakes work • Act as the central coordination point across Clinical, Legal, Finance, Product, Service Operations, and Account Management • Manage timelines, dependencies, and deliverables across concurrent submissions • Ensure high-quality outputs under pressure while maintaining a strong candidate and partner experience

• System Integrity: Ensuring every department (Sales, Marketing, Success, Admin) has a clear, documented, and automated operating system. • Strategic Execution: Turning high-level visionary goals into project plans with clear owners, timelines, and milestones. • Performance Management: Ensuring the team hits their KPIs and that the company stays on its "rhythm" (Daily/Weekly/Quarterly). • Operational Leverage: Finding ways to increase output and revenue without a linear increase in headcount or effort. • Infrastructure & Systems Architecture: Own the tech stack. Ensure our project management software, CRM, and communication tools are integrated and used properly. • Departmental Performance & Accountability: Conduct weekly 1:1s with department heads to track progress against quarterly rocks. • Project Management & Delivery: Act as the central hub for major company initiatives (e.g., event launches, geographic expansion). • Financial & P&L Oversight: Review departmental spending and budgets with the CEO. • Operating Rhythm: Own the cadence: Daily Huddles, Weekly Lead-Team Meetings, and Quarterly Offsites.

• Develop and implement systems and processes in the creative team • Automate repetitive tasks through AI adoption • Generate weekly reports on team and product performance • Manage operational layers including asset management and budget tracking