Role Description Own engineering strategy for the product and partner closely with the Principal Architect on system-level decisions, while driving execution and delivery. - This is not a hands-off leadership role. You will operate as a primary individual contributor (80 to 90 percent hands-on) during the initial build phase, writing and shipping production code while setting the technical foundation and delivery pace. - Over time, transition from a deeply hands-on builder into a leader of a growing engineering organization, balancing technical direction with team development as the product scales. - Build high-concurrency backend services in Go or Python and leverage edge-first engineering with Cloudflare Workers and Durable Objects for global state synchronization. - Architect production-grade AI infrastructure, including RAG pipelines and streaming LLM orchestration, while creating the underlying systems that enable the team to build with AI effectively. - Integrate collaborative primitives such as CRDTs and real-time presence indicators to power a seamless multiplayer editing experience. - Partner with product and design leadership to translate ambiguous product direction into clear technical plans and staged delivery. - Establish and champion engineering excellence across the full stack, covering API design, type safety, testing, observability, and incident response. - Drive build-vs-buy decisions and manage multi-tenant infrastructure using GCP primitives such as Spanner, Pub/Sub, and Cloud Run, ensuring systems are scalable, reliable, and secure. Qualifications - 12+ years of professional software engineering experience, including 5+ years in senior leadership roles managing both individual contributors and engineering managers. - A track record of building and scaling products from zero to production, including direct ownership of at least one true zero-to-one B2B product or platform build. - Expert-level capability in Go or Python, along with React and TypeScript/Next.js. Must have written meaningful production code within the last 12 months and be willing to stay hands-on through the initial build phase. - Deep technical fluency in headless CMS architectures and structured content systems (e.g., JSON-based schemas or Portable Text), and how they power flexible frontend applications. - Direct experience building AI systems and developer tooling, including ownership of the underlying infrastructure (not just API integrations). - Advanced proficiency designing and operating globally distributed systems using GCP and Cloudflare, particularly for real-time data synchronization and shared state. - Strong systems thinking with the ability to balance speed and long-term scalability, and make decisions in ambiguous environments. - Proven ability to build and scale an engineering team from a small founding group, including hiring, developing, and leading engineers and managers. - Strong technical leadership with the ability to set standards, guide architectural direction, and raise the bar across the team. - Bachelor’s degree in Computer Science or related field; Master’s preferred. Requirements - Base Salary: $216-270K per year. Note: Final offers are based on individual technical depth, experience, and location. - Quarterly/annual bonus plus equity package. - Health, dental, and vision insurance. - Results-oriented PTO, sick days, and paid holidays. - Parental leave, family planning, and monthly wellness/learning stipends. - Equal Opportunity & Fair Chance: Decisions are made regardless of protected status. Pursuant to the San Francisco Fair Chance Ordinance, qualified applicants with arrest/conviction records will be considered. - Work Authorization: U.S. work authorization without sponsorship is required. Eligibility is confirmed via E-Verify.

Title: Director, Chemical (Drug Substance) Manufacturing Management Location: Brisbane, CA Job Description: Why Join Us? Be a hero for our rare disease patients At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them. Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work. If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team. Position Summary: ultrafocused – Work together to fearlessly uncover new possibilities The Director, Drug Substance Manufacturing provides technical and operational leadership for drug substance manufacturing activities supporting Ultragenyx’s small molecule and oligonucleotide programs. This role is responsible for execution of departmental manufacturing strategies, management of external CMOs, and delivery of reliable clinical and commercial supply under cGMP conditions. The Director partners cross‑functionally to ensure safe, compliant, and efficient manufacturing while operating within established functional strategies. Work Model: Flex: This role will typically require onsite work 2-3 days each week or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite. Responsibilities: - Lead and manage drug substance manufacturing for synthetic molecules and oligonucleotides in a cGMP environment, supporting both clinical and commercial supply. - Oversee production planning, execution, and performance tracking to ensure reliable fulfillment of agreed manufacturing services. - Manage and strengthen CMO relationships, including selection, onboarding, governance, and ongoing performance management. - Lead or contribute to CMC projects across the small molecule and oligonucleotide portfolio, ensuring alignment with development and supply strategies. - Author and/or provide expert input into CMC sections for global regulatory filings, including INDs, IMPDs, NDAs, and MAAs. - Serve as an integral member of cross‑functional and cross‑discipline CMC teams for programs containing synthetic components. - Oversee process development, optimization, technology transfer, and lifecycle management, including change controls, deviations, and investigations. - Ensure development and maintenance of manufacturing-related documentation, including Design History Files and Quality Risk Management Plans. - Drive RFPs, Statements of Work, Master Service Agreements, and other manufacturing and quality governance documents. - Promote continuous improvement, knowledge management, and operational excellence while representing Drug Substance Manufacturing on global and cross‑functional teams. Requirements: - Ph.D. in chemistry, chemical engineering, organic chemistry, or a related discipline, or equivalent industry experience. - 8–12 years of pharmaceutical or biopharmaceutical experience with progressive responsibility in CMC and manufacturing. - Demonstrated experience in managing small molecule synthetic chemistry, pharmaceutical CMC development, process scale‑up, and cGMP manufacturing. - Demonstrated experience managing and participating in cross‑functional CMC teams. - Strong background in development and clinical manufacturing of small molecule drug substances; experience with oligonucleotides is a plus. - Familiarity with QbD principles, DoE, process scale-up and optimization, validation/qualification, and phase‑appropriate controls. - Solid knowledge of cGMP requirements, ICH guidelines, and phase‑appropriate controls.. - Familiarity with analytical development and quality control is advantageous. - Strong track record of building and sustaining effective CMO partnerships. - Demonstrated ability to lead teams, manage complexity, and deliver results in a matrixed environment. - Excellent written and verbal communication skills in English; additional languages are a plus. - Demonstrated commitment to leadership development, coaching, and continuous learning. Physical Demand Requirements Office‑based role with occasional presence in manufacturing and partner facilities. requiring GxP gowning and wear protective clothing over the head, face, hands, feet, and body may be required during site visits or when attending as person-in-plant. This requires the ability to change clothes into appropriate gowning and personal protective equipment. #LI-CT1 #LI-Hybrid The typical annual salary range for this full-time position is listed below. This range reflects the characteristics of the job, such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicant's geographic location. This position is eligible for annual bonus and equity incentives. Actual individual pay is determined by demonstrated experience and internal equity alignment. Pay Range $212,800—$262,800 USD Full Time employees across the globe enjoy a range of benefits, including, but not limited to: · Generous vacation time and public holidays observed by the company · Volunteer days · Long term incentive and Employee stock purchase plans or equivalent offerings · Employee wellbeing benefits · Fitness reimbursement · Tuition sponsoring · Professional development plans * Benefits vary by region and country Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process. See our CCPA Employee and Applicant Privacy Notice. See our Privacy Policy. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation.

Title: Director of Hotel Intelligence, Americas Location: United States, Remote Job Description: If you're a hotel finance expert who's energised by getting in front of customers, translating complex P&L data into compelling narratives, and helping hospitality businesses see their performance in a completely new way — this role was built for you! As Director of Hotel Intelligence for the Americas, you'll be the subject matter authority on profit benchmarking and USALI, partnering with Duetto's sales teams to bring the combined power of Duetto and HotStats to hotels, resorts, and casinos across the region. What Makes Us Different? Duetto is the hospitality industry's leading revenue management platform, founded in 2012 by former Wynn Resorts executives who knew the industry needed better technology. We built the world's first Revenue & Profit Operating System — a suite of tools (GameChanger, ScoreBoard, BlockBuster, Advance and more) that goes beyond room pricing to give hotels, resorts and casinos a complete picture of their revenue and profitability. Trusted by clients ranging from independent boutique hotels to global chains, we've been named the #1 Revenue Management Software by HotelTechAwards four years running and the #1 Best Place to Work in Hotel Tech in 2025. Backed by GrowthCurve Capital since 2024, we're accelerating our investment in AI — and we're genuinely passionate about the industry we serve. We build products we're proud of, for customers we care about. A key part of that vision is HotStats — a Duetto company and the global authority on hotel profit benchmarking. HotStats provides unparalleled profitability and cost intelligence, enabling hotels to benchmark performance and make smarter, data-led decisions. Together, Duetto and HotStats give hoteliers a view no other platform can match. What You'll Be Doing - You'll serve as the primary subject matter expert on hotel P&L benchmarking, USALI, and profit intelligence across all sales and marketing activity in the Americas — the person in the room who makes the data make sense to a CFO. - You'll deliver technically grounded product demonstrations and executive presentations that connect HotStats benchmarking with Duetto revenue optimisation, building a unified value narrative that resonates with finance and revenue leaders alike. - You'll identify and articulate operational and financial gaps within prospect and client organisations, positioning the combined Duetto and HotStats suite as the path to measurable performance improvement. - You'll partner with Duetto's Enterprise and Casino sales teams to surface HotStats opportunities within existing accounts and contribute to joint pursuit strategies for new logos across the region. - You'll collaborate with Marketing to develop regionally relevant content, campaigns, and thought leadership that build pipeline and strengthen brand authority in the Americas. - You'll maintain accurate CRM records across pipeline activity, client interactions, and deal progression — and feed structured market insights back to Sales, Product, and Marketing to sharpen GTM strategy and positioning. What We're Looking For You may be a good fit if you have: - A background in hotel finance combined with 6+ years of go-to-market experience in sales, solutions engineering, or pre-sales within hospitality technology or a closely adjacent industry - Deep knowledge of hotel financial operations: P&L structure, cost benchmarking, and USALI - Demonstrated ability to deliver technical product demonstrations and executive-level presentations with equal confidence - Experience navigating multi-stakeholder sales cycles and influencing executive decision-makers including CFOs and ownership groups - Willingness to travel approximately 30%, including internationally Strong candidates may also have: - Prior experience in a Solutions Engineer, Pre-Sales Consultant, or technical sales role within hospitality technology - A background in hotel finance or revenue operations within a hotel group or management company - Familiarity with revenue management systems, profit benchmarking platforms, or BI tools in a hospitality context - Knowledge of the Duetto platform or HotStats product suite - Fluency in Spanish and/or Portuguese Why Duetto? - A story worth telling. The combination of Duetto's revenue optimisation and HotStats' profit benchmarking is genuinely unlike anything else in the market — you'll be evangelising a product that solves a real, unsolved problem for hotel finance leaders. - Deep domain meets real commercial impact. This is a role where your hotel finance expertise isn't background knowledge — it's the core of the job. You'll use it every day in front of customers who speak your language. - AI is how we work. Duetto is an AI-first organisation across every function — you'll have tools and workflows that make you sharper and faster than in any comparable role elsewhere. - A market that's ready. Hospitality has historically relied on gut feel and lagging benchmarks — the appetite for standardised, data-led profit intelligence is accelerating, and you'll be at the front of that shift in the Americas. - Brand that opens doors. HotelTechAwards #1 RMS four years running, #1 Best Place to Work in Hotel Tech in 2025 — the reputation precedes you. The Details - Location: Remote (US) - Department: Sales - Travel: Approximately 30%, including international Duetto is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by applicable law. Sound like you? You don't need to tick every box. If you have the hotel finance fluency, the presence to hold a room, and a genuine passion for helping hospitality businesses perform better — we'd love to hear from you. #LI-REMOTE

Title: Director of Programs, IRiSS Location: Stanford, CA United States - ScheduleFull-time - Job Code4112 - Employee StatusFixed-Term - GradeJ - Requisition ID108945 - Work ArrangementHybrid Eligible Job Description: This position has been deemed critical by the School of Humanities and Sciences Dean's Office and is exempt from the hiring freeze. The School of Humanities and Sciences (H&S) is the foundation of a liberal arts education at Stanford. The school encompasses 24 departments and 25 interdisciplinary programs. H&S is home to fundamental and applied research, where free, open, and critical inquiry is pursued across disciplines. As the university's largest school, H&S serves as the foundation of a Stanford undergraduate education no matter which discipline students pursue as a major. Graduate students work alongside world-renowned faculty to pursue and shape foundational research that leads to breakthroughs and discoveries that shed new light on the past, influence the present, and shape the future. Together, faculty and students in H&S engage in inspirational teaching, learning, and research every day. Stanford Institute for Research in the Social Sciences (IRiSS) Expanding access to novel data sources, the development of powerful computing tools, and innovation in quantitative and qualitative research methods are opening a new frontier for social scientists to explore bold, inventive research questions. In this era of burgeoning social-science research, the Stanford Institute for Research in the Social Sciences (IRiSS) facilitates first-rate interdisciplinary collaborations, trains the next generation of scholars, and incubates medium- to long-term research projects to address critical social challenges. IRiSS ensures that world-class, evidence-based research is produced to meet evolving problems in areas of governance and democracy, economic inequality, immigration policy, and other social issues that affect communities across the globe. POSITION SUMMARY IRiSS is seeking a Director of Programs to oversee the planning, implementation, management, and evaluation of our existing portfolio of programs, as well as to develop new programs. Current programs include: - IRiSS Predoctoral Researchers Program - IRiSS Research Experience Programs: Community College Research Experience Programs (Foothill College, Mission College; online and in-person) and Community College Research Assistant Internship Program (Foothill College, Mission College) - IRiSS Research Centers and Initiatives: the Center for Affective Science, the Center for American Democracy, and the Center for Global Ethnography, the Stanford Institute for Excellence in Survey Research The position reports to the IRiSS executive director. A strong on-campus presence is essential to foster community, visibility, and direct engagement with faculty, graduate and undergraduate students, post baccalaureate researchers, and community college students who have been selected as research assistant interns in social science research labs. This is a 100% FTE, two-year fixed-term, exempt position, based on Stanford's main campus. It will be considered for an option of telecommuting (hybrid of working on-site and off-site), subject to operational need. If you believe that this opportunity is a match for your knowledge, skills and abilities, we encourage you to apply. For full consideration, please include a résumé and cover letter. Thank you for considering employment opportunities with the School of Humanities and Sciences. CORE DUTIES - Develop and manage research programs by conducting research activities, including outreach to varied stakeholders within the program, assigning resources and making program improvement recommendations that impact policies and programs. - Identify, recommend, and implement opportunities for new research. - Source, collect and analyze data, create reports, review and explain trends; formulate and evaluate alternative solutions and/or recommendations to achieve the goals of the program or function. - Write and/or edit complex content for proposals, research grants, peer-reviewed publications, and other program activities. - Contribute to and inform on strategic program/entity planning and related funding and financial sustainability. - May advise students and/or coach/mentor clients. - Develop or contribute to outreach strategy related to program communications, development, partnerships, and fundraising/funding. - Coach and mentor program staff. - Other duties may also be assigned. EDUCATION AND EXPERIENCE: Bachelor's degree and three years of relevant experience or combination of education, training, and relevant experience. An advanced degree in the social sciences or a related field is highly preferred. KNOWLEDGE, SKILLS, AND ABILITIES - Ability to develop program partnerships and funding sources - Excellent oral, written, and analytical skills, exhibiting fluency in area of specialization - Ability to oversee and direct staff and student workers - Basic knowledge of managing budgets and financial plans In addition, preferred requirements include: - Experience working with university faculty as well as students at both the undergraduate and graduate levels. - Broad understanding of the social science disciplines represented in the School of Humanities & Sciences, including familiarity with both quantitative and qualitative methods, data security protocols, IRBs, and research administration offices - Experience managing academic programs or research support services, including evidence-based program evaluation - Experience organizing and hosting typical academic events like conferences, workshops, panel discussions, etc. - Proficiency in cloud-based collaboration, especially using Google Workspace products, running hybrid meetings via Zoom, using project management platforms, etc. - Familiarity with basic communications tools like Drupal or Wordpress-based websites, MailChimp and other kinds of mailing lists, Qualtrics, PowerPoint or Google Slides, Canva or InDesign, major social media platforms, basic audio/video editing - Readiness to integrate agentic AI (Claude Cowork, Codex, etc.) into existing systems and workflows WORKING CONDITIONS: - May work extended hours, evenings or weekends. - May travel locally. - Occasional overnight travel. The expected pay range for this position is $116,966 to $150,114 per annum. Stanford University provides pay ranges representing its good faith estimate of the salary or hourly wage the university reasonably expects to pay for a position upon hire. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs. At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website provides detailed information on Stanford's extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process. Why Stanford is for You Imagine a world without search engines or social platforms. Consider lives saved through first-ever organ transplants and research to cure illnesses. Stanford University has revolutionized the way we live and enrich the world. Supporting this mission is our diverse and dedicated 17,000 staff. We seek talent driven to impact the future of our legacy. Our culture and unique perks empower you with: - Freedom to grow. We offer career development programs, tuition reimbursement, or audit a course. Join a TedTalk, film screening, or listen to a renowned author or global leader speak. - A caring culture. We provide superb retirement plans, generous time-off, and family care resources. - A healthier you. Climb our rock wall, or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits. - Discovery and fun. Stroll through historic sculptures, trails, and museums. - Enviable resources. Enjoy free commuter programs, ridesharing incentives, discounts and more The job duties listed are typical examples of work performed by positions in this job classifications and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned. Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities.