Unleashing the power of genomics at scale
Staff Bioinformatics Scientist, Oncology Applications
Location
California + 2 moreAll locations: California | Massachusetts | Washington
Posted
63 days ago
Salary
$135K - $170K / year
Seniority
Lead
Job Description
Staff Bioinformatics Scientist, Oncology Applications
Ultima Genomics
• Develop, optimize, and maintain scalable bioinformatics pipelines for NGS data analysis such as WGS, WES, RNA-seq, and single-cell • Design and implement novel algorithms for secondary and tertiary NGS analysis tailored to Ultima’s sequencing chemistry • Lead and execute multiple projects simultaneously, effectively prioritizing deliverables in alignment with evolving company goals • Perform benchmarking and validation studies • Analyze large-scale genomic datasets and generate actionable insights for internal R&D, product development, and external collaborators • Collaborate closely with wet-lab scientists, software engineers, and product teams to translate experimental results into improved workflows and tools • Support external collaborations by preparing technical analyses, reports, presentations, and data summaries for customers, partners, and conferences • Contribute to scientific publications, application notes, white papers, and other external communication materials as needed • Participate in customer-facing discussions to explain data analysis approaches, performance metrics, and platform capabilities • Document methods clearly and communicate findings effectively to both technical and non-technical audiences • Stay current with emerging technologies and advances in genomics, computational biology, machine learning, and cancer biology • Other duties as assigned
Job Requirements
- PhD in Bioinformatics, Computational Biology, Genomics, Computer Science, or related field; or MS with significant industry experience
- PhD with 5+ years or MS with 8+ years of hands-on experience analyzing NGS data required
- Strong programming skills in Python and/or C++
- Experience with common bioinformatics and somatic variant calling tools such as BWA, minimap2, GATK, samtools
- Proficiency in Linux/Unix environments and workflow management systems (Nextflow, Snakemake, WDL)
- Experience working with large datasets in cloud environments (AWS, GCP)
- Solid understanding of genomics and cancer biology
- Strong statistical and data analysis skills
- Demonstrated ability to manage multiple concurrent priorities and deliver high-quality work under tight timelines
- Knowledge of machine learning approaches applied to genomics
- Clear and confident communicator, comfortable in external-facing settings
- Experience in regulated environments (CLIA, CAP) is a plus
- Thrive in a fast-paced, startup environment with evolving priorities
- Demonstrated scientific rigor and analytical thinking
- High ownership, accountability, and bias toward action
- Collaborative mindset with cross-functional agility
Benefits
- medical, dental, vision, life, and disability insurance
- 401(k) retirement plan
- flexible spending & health savings account
- paid holidays
- paid time off
- employee assistance program
- other company benefits
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