Edetek logo
Edetek

This is a remote position, and we are open to candidates based in the United States. EDETEK is an equal opportunity employer and does not unlawfully discriminate against employees or applicants for employment on the basis of an individual’s race, color, religion, creed, sex, national origin, age, disability, marital status, veteran status or any other status protected by applicable law.

Senior Biostatistician

Location

Poland

Posted

51 days ago

Salary

0

Seniority

Senior

English

Job Description

Senior Biostatistician

Edetek

The Senior Biostatistician provides statistical support and leadership for oncology clinical trials across multiple phases of development. This role works closely with sponsors and cross-functional teams to support study design, protocol development, statistical analysis planning, data interpretation, and study reporting. The Senior Biostatistician is expected to contribute strong technical expertise, effective client communication, and high-quality delivery of statistical work products in a CRO environment.  Candidates with CRO experience are strongly preferred. Experience supporting oncology studies and Data Monitoring Committee (DMC/IDMC) activities is also preferred.  Essential Functions and Responsibilities - Provide statistical support for clinical trials from study start-up through final reporting and regulatory submission.   - Contribute statistical input to study design, sample size determination, endpoint definition, randomization, and analysis strategy.   - Author or review statistical sections of protocols, statistical analysis plans, mock shells, and other study documents.   - Collaborate with sponsors, clinical teams, data managers, statistical programmers, medical writers, and regulatory teams throughout the study lifecycle.   - Review statistical analyses and outputs, including tables, listings, and figures, to ensure quality, accuracy, and consistency.   - Support interim analyses, safety reviews, efficacy analyses, and final study reporting.   - Participate in the review of ADaM specifications, derived endpoints, and analysis datasets.   - Support the preparation of DMC materials, including review of analysis outputs and summaries for DMC meetings, in accordance with applicable procedures and confidentiality requirements.   - Interpret statistical results and communicate findings clearly to internal teams and sponsors.   - Ensure study deliverables are completed on time and in compliance with SOPs, regulatory requirements, and sponsor expectations.   - Support responses to sponsor questions, audit requests, and health authority queries related to statistical matters.   - Provide guidance to junior statisticians and support departmental process improvement and standardization efforts.   - Contribute to proposal development, bid defenses, and budget assumptions as needed.   Oncology-Specific Responsibilities  - Support oncology studies involving endpoints such as ORR, DOR, PFS, OS, BOR, CBR, and TTR.   - Contribute to statistical strategies for time-to-event analyses, censoring rules, subgroup analyses, and sensitivity analyses.   - Support studies using RECIST, iRECIST, or other disease-specific response criteria, as applicable.   - Work with cross-functional teams on tumor assessment data, adjudication, and endpoint derivation.   DMC / IDMC Experience - Support statistical activities related to DMC/IDMC reviews for ongoing clinical trials.   - Assist with preparation and review of DMC analysis outputs, safety summaries, and meeting materials.   - Contribute to DMC charter review and statistical content, where applicable.   - Work effectively within blinded and unblinded team structures and maintain strict confidentiality.

Job Requirements

  • Master’s degree or PhD in Statistics, Biostatistics, or a related quantitative field.
  • Typically 5 to 8+ years of relevant biostatistics experience in clinical research, pharmaceutical, biotechnology, or CRO settings.
  • CRO experience strongly preferred.
  • Experience supporting oncology clinical trials preferred.
  • Experience supporting DMC/IDMC activities preferred.
  • Strong knowledge of statistical methodology used in clinical trials, including survival analysis, categorical data analysis, and longitudinal data analysis.
  • Good understanding of ICH, GCP, and applicable regulatory requirements.
  • Experience developing or reviewing SAPs, protocols, and statistical outputs.
  • Familiarity with CDISC standards, including SDTM and ADaM.
  • Proficiency in SAS required. Familiarity with R is a plus.
  • Strong written and verbal communication skills.
  • Ability to manage multiple studies and priorities in a fast-paced CRO environment.
  • Preferred Qualifications
  • PhD preferred but not required.
  • Experience supporting global clinical trials and regulatory submissions.
  • Experience in early-phase or late-phase oncology studies.
  • Experience interacting directly with sponsors in a client-facing role.
  • Mentoring or training experience is a plus.
  • Working Relationships
  • The Senior Biostatistician works closely with:
  • Sponsors and external clients
  • Biostatistics and statistical programming teams
  • Data management teams
  • Clinical operations and medical teams
  • Medical writing and regulatory teams
  • DMC-related teams, where applicable
  • Success Measures
  • Timely and high-quality delivery of statistical outputs
  • Strong support for study design, analysis, and reporting
  • Positive sponsor and team feedback
  • Compliance with timelines, SOPs, and regulatory expectations
  • Effective collaboration across functions

Benefits

  • Benefits vary by country, but remain competitive. Below is a sample of the benefits offered to U.S. employees.
  • Choice of comprehensive Medical, Vision and Dental Insurance plans
  • Paid vacation time and sick days
  • Corporate holidays annually
  • Participation in the 401K Plan
  • Comprehensive perks and discount programs for AAA, wholesale, insurance, Rx, fitness, pets, entertainment, etc.
  • Health Advocate and Employee Assistance Program
  • Location
  • This is a remote position, and we are open to candidates based in the United States, India, Ukraine, Bulgaria, Poland, and Romania.
  • Equal Opportunity Employer Statement
  • EDETEK is an equal opportunity employer and does not unlawfully discriminate against employees or applicants for employment on the basis of an individual’s race, color, religion, creed, sex, national origin, age, disability, marital status, veteran status or any other status protected by applicable law. This policy applies to all terms, conditions and privileges of employment, including recruitment, hiring, placement, compensation, promotion, discipline, and termination. Whenever possible, the company makes reasonable accommodations for qualified individuals with disabilities to the extent required by law.

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