Homebased role ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development We are currently seeking a Senior Global Regulatory Scientist to join our diverse and dynamic team. As a Senior Global Regulatory Scientist at ICON, you will provide high-level regulatory and scientific expertise to support global development strategies and submissions. You will collaborate with sponsors and cross-functional teams to navigate complex regulatory pathways and enable successful product development. What You Will Be Doing: - Leading the development of global regulatory strategies for clinical programmes, including plans for key health authority interactions and milestones. - Authoring and reviewing complex regulatory documents such as clinical trial applications, briefing books, and major submission components. - Interpreting evolving global regulations, guidelines, and precedents, and advising teams on implications for programme design and execution. - Providing strategic input into clinical development plans, risk management strategies, and labelling considerations. - Representing regulatory functions in sponsor and health authority meetings, ensuring clear, scientifically robust communication. - Mentoring junior regulatory colleagues and contributing to internal best practices, templates, and knowledge-sharing initiatives. Your Profile: - Bachelor's degree in life sciences, pharmacy, medicine, or a related discipline, or equivalent regulatory experience. - 4+ years experience in regulatory affairs or regulatory science within pharma, biotech, or CRO environments. - Strong knowledge of global clinical development regulations (e.g., FDA, EMA, ICH) and regional requirements. - Excellent scientific, analytical, and critical-thinking skills, with the ability to integrate complex data into regulatory positions. - Outstanding English written and verbal communication abilities - Proven experience interacting with health authorities and leading cross-functional regulatory projects What ICON can offer you: Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family. Our benefits examples include: - Various annual leave entitlements - A range of health insurance offerings to suit you and your family’s needs. - Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead. - Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being. - Life assurance - Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others. Visit our careers site to read more about the benefits ICON offers. At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here. Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles. Are you a current ICON Employee? Please click here to apply

• Serve as a core toxicology and nonclinical safety representative on project teams, providing scientific leadership and regular updates to teams and management. • Design, implement, manage and interpret nonclinical safety assessment programs in support of drug development candidates. • Originate novel study designs and protocols to address complex scientific questions and develop integrated strategies to achieve project goals. • Critically evaluate and interpret experimental data and author key sections of internal governance documents, INDs, BLAs, NDAs and other regulatory documents. • Coordinate and collaborate with internal Amgen scientists and external partners to advance research and development programs. • Participate in licensing, due diligence, and external partnering activities, as appropriate. • Mentor and support other Amgen scientists in the design execution and oversight of nonclinical studies. • Represent Amgen on nonclinical safety topics in interactions with U.S. and international regulatory agencies, and contribute to external industry initiatives aimed at advancing drug safety assessment paradigms.

Work Schedule Standard (Mon-Fri) Environmental Conditions Laboratory Setting, Office Job Description As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer. Location: This is a remote customer facing scientist position covering a Pacific Northwest and British Columbia territory. Residency within the Pacific Northwest territory is preffered. No relocation assistance will be provided. DESCRIPTION: Join our collaborative team at Thermo Fisher Scientific as a Staff Scientist, Field Applications and contribute by enabling customers to solve complex downstream and purification challenges. You'll serve as a technical expert, providing comprehensive support across our downstream technology platforms while building strong relationships with customers, sales teams, and internal partners. This role offers the opportunity to work with advanced scientific instrumentation and contribute to breakthroughs that make the world healthier, cleaner, and safer. Working both independently and collaboratively, you'll deliver technical training, optimize applications, troubleshoot complex issues, and demonstrate our technologies through presentations. Your expertise will help customers achieve their research and development goals while supporting the adoption of our solutions across multiple scientific disciplines. You'll have the opportunity to support colleagues, lead strategic projects, and contribute to product development by providing valuable customer feedback to our R&D teams. This position combines scientific expertise with customer engagement, allowing you to contribute to both technical advancement and business growth. REQUIREMENTS: • Advanced Degree plus 6 years of experience, or Bachelor's Degree plus 8 years of experience. • Preferred Fields of Study: Chemistry, Biochemistry, Biology, Materials Science, Engineering, or related scientific field • Technical knowledge in one or more core application areas required (downstream process for monoclonal antibodies, viral vectors, vaccines, or related fields) • Successful experience in customer-facing technical support and training • Strong communication skills with ability to explain complex concepts to diverse audiences • Problem-solving abilities and analytical troubleshooting expertise • Project management and organizational skills • Ability to work independently while collaborating effectively across teams • Proficiency in relevant software applications and data analysis tools • Presentation and technical writing capabilities • Fluency in English required; additional languages beneficial • Ability to travel up to 50-75% (2 weeks a month) within assigned territory • Valid driver's license and passport for international travel where required • Experience with method development and optimization • Leadership abilities and mentoring skills • Knowledge of regulatory requirements and quality systems (GMP, GLP) preferred Compensation and Benefits The salary range estimated for this position based in Washington is $104,000.00–$154,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: - A choice of national medical and dental plans, and a national vision plan, including health incentive programs - Employee assistance and family support programs, including commuter benefits and tuition reimbursement - At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy - Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan - Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

• Develop and maintain peer benchmarking models using platform usage signals to produce unit economic metrics: • Credits per 1,000 jobs. • Credits per TB scanned. • Workload mix (% spend on Data Engineering, BI, Data Science, ELT, etc.). • Cost efficiency percentiles (p25 / p50 / p75 / p90) by industry and customer segment. • Construct peer groups using unsupervised ML techniques (clustering, dimensionality reduction) on account-level feature vectors — combining industry vertical, usage fingerprint, and size normalization into meaningful comparable cohorts. • Engineer a benchmarking feature store from large-scale platform usage datasets using Snowpark and dbt, covering compute, storage, and workload dimensions at account and industry level. • Apply statistical rigor to handle skewed distributions, outlier accounts, and temporal variation in usage patterns across a highly diverse customer base. • Package benchmarking outputs into repeatable advisory assets — cost optimization playbooks, benchmarking dashboards, and narrative summaries — that can be consumed by field teams and scaled across the customer base. • Partner with Account Executives, Solution Engineers, and Customer Success Managers to embed FinOps benchmarking into the customer lifecycle — translating analytical outputs into field-ready narratives and customer conversations. • Collaborate cross-functionally with Product, FinOps, and Sales Strategy to ensure advisory insights feed back into product priorities and field positioning.