Overview The Strategic Account Lead (SAL) role leads strategic engagement and contracting with target key accounts in order to drive growth, revenue, and joint value creation for Alnylam and the customer by enabling and optimizing access to Alnylam products and driving innovation for patients and health care providers. Key Responsibilities The Strategic Account Lead (SAL) will provide innovative, influential account engagement to shape and deliver the strategy for Alnylam Strategic Accounts in order to achieve access, create value and deliver profitable growth for Alnylam. - Lead the development and execution of the comprehensive account strategy for target accounts to bring the best of Alnylam to the customer and to maximize profitability, revenue growth and market share for Alnylam - - Analyze and synthesize information from multiple sources to identify and prioritize business opportunities across the account by applying relevant frameworks and analytical methods - Work with the Alnylam Leadership Team to co-develop and agree on strategies, programs objectives and KPIs for target regional accounts aligned with organizational and brand priorities and the wider business strategy - Support the account team with the prioritization of solutions, programs and specific pull-through tactics to ensure sustainable growth and mutual value creation - Anticipate likely market and customer developments, identify third party influence factors and shape the account strategy accordingly - Partner with target healthcare systems and organized customers to foster innovation in care through the adoption of Alnylam’s products - - Engage senior level stakeholders to influence policies, decisions and perceptions to enable patients to effectively navigate the treatment journey and ensure appropriate use of Alnylam products - Facilitate the introduction of new products and indications with institutional stakeholders by ensuring adequate budget allocation at the strategic account level - Leverage a range of strategies and tactics to maximize the level and quality of access for Alnylam products - Identify programs to partner with the Organized Customer to enhance the system of care and clinical decision making - Provide insights, education and information about scientific, clinical and technological innovation - Facilitate strategic partnership with account stakeholders to create mutual value for Alnylam and customers and deliver strategic goals - - Identify and maintain strong relationships with senior business stakeholders (Chief, VP, Director) in target accounts to support access for Alnylam’s products across the company portfolio - Strengthen the perception of Alnylam as a strategic partner by sharing insights and information to support patient identification and improving the delivery of care by establishing treatment pathways and protocols - Provide clear direction to other field teams to identify and prioritize stakeholders within their target accounts - Negotiate, review and agree contracts, incorporating solutions to strengthen partnerships with strategic account stakeholders - Collaborate with other functional and business leaders to ensure adequate Voice of the Customer to inform strategic planning across all stakeholders and channels - Support the delivery of account goals for National accounts, working closely with the Strategic Accounts Team - - Support the execution and pull through of contracting and initiatives with national organized customers to ensure value maximization - Measure, report and communicate value delivered for national organized customers in order to strengthen customer partnership - Share insights gathered through customer engagement Qualifications - - Bachelor’s degree, emphasis in Accounting, Marketing, Business Administration or equivalent work experience in business management, ideally complemented by an MBA - Minimum 7 years of experience in B2B selling in a life sciences environment - Previous account management experience with health systems and/or hospitals/ IDNs - High level of confidence and capability to understand and communicate complex scientific concepts to a range of stakeholders, plus executive presence and communication skills to engage with a C-Suite audience - Expertise and understanding of dynamic market access value models such as value-based propositions and budget impact and cost effectiveness models, etc - Strong interpersonal skills including written and oral communication skills, ability to synthesize data, interpret and translate into compelling and clear commercial strategies and plans - Demonstrated ability to successfully mobilize a cross-functional team, including interpersonal skills to foster collaboration and succeed in a highly matrixed environment by leading without direct authority - Understanding of the IDN environment, including coverage and reimbursement, pricing and contracting, formulary management and health technology assessment - Strong analytical skills and ability to think critically, challenge conclusions and underlying assumptions - Ability to synthesize multi-source information (qualitative and quantitative) to develop strategic plans - Knowledge of value based healthcare and outcome based models - Executive presence and the ability to interact and negotiate with C-suite customers - Highly proficient in Microsoft; Excel, Word, and PowerPoint Additional Preferred Experience - - Master’s degree: Master of Business Administration (MBA) preferred - Active membership of relevant pharmaceutical associations would be beneficial #LI-ST1 #LI-Remote U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we're helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Director, Consumer Debit, National Accounts Overview Our North America sales organization is seeking to build a diverse, strategic and consultative workforce of world-class relationship managers, problem-solvers, and technologists. We are looking for an Account Manager to join our team who can drive value for one of our largest, most strategic national issuers. The Director, Account Management role is a senior individual contributor responsible for driving strategy, revenue growth, financial performance, and execution for a large, complex Consumer Debit portfolio. The role serves as the primary client relationship owner on the Consumer Debit portfolio, accountable for outcomes and long-term strategic partnership development. This position drives portfolio and revenue growth through consultative sales leadership, portfolio and initiative expansion, and strategic account planning, while partnering closely with Product, Services, Finance, Analytics, and Technology to translate client priorities into scalable, enterprise solutions. Success in this role requires strong commercial judgment, excellent, executive-level communication skills, robust financial acumen, and the ability to lead high-impact initiatives across a matrixed organization. Responsibilities Account & Client Relationship Leadership• Own end-to-end strategy and execution for major portfolio-related initiatives, aligning Mastercard capabilities to client priorities and market dynamics.• Serve as the primary client portfolio relationship owner, leading commercial discussions, opportunity development, and long-term account growth strategies.• Act as a trusted advisor to key client stakeholders, delivering insight-driven recommendations that strengthen partnerships and portfolio performance. Financial & Commercial Ownership• Deliver consistent performance results across annual financial objectives, revenue targets, and portfolio goals.• Drive portfolio growth and profitability through consultative sales leadership, disciplined financial management, and identification of expansion opportunities within the existing client relationship.• Lead financial strategy and decision support for major commercial activities, including renewals, extensions, and new opportunities. Strategic Execution & Operational Leadership• Lead complex, cross-functional initiatives that address strategic or operational needs and enable sustainable portfolio optimization and growth.• Partner with internal teams to deliver integrated solutions that improve efficiency, scalability, and client outcomes.• Oversee planning and execution of strategic initiatives, managing risks, interdependencies, and trade-offs to ensure successful delivery. Cross-Functional Integration & Influence• Act as the central integrator across Product, Services, Finance, Analytics, and Technology to align strategy, execution, and delivery supporting the entire Consumer Debit portfolio.• Influence stakeholders driving alignment, accountability, and results across teams.• Proactively surface and resolve issues that could impact portfolio performance or client outcomes. Enterprise & Cross-Product Initiative Contribution• Advance the Bank's and Mastercard's priorities by supporting cross-product / cross-portfolio initiatives that drive performance, consistency, and scale across Consumer, SMB, and adjacent portfolios.• Contribute to the evolution of enterprise best practices by shaping operating models, portfolio management approaches, and scalable capabilities that can be applied across products and lines of business.• Act as a trusted partner across stakeholders, modeling a consultative, results-oriented approach that reflects Mastercard's values and reinforces a client-centric, enterprise mindset. Experience & Qualifications• Comprehensive experience executing and delivering innovative solutions, engagement initiatives and thought leadership related to Consumer Credit, Consumer Debit or Small Business portfolios• Demonstrated in-depth knowledge of MasterCard's core products with a focus on Consumer Credit, Consumer Debit or Small Business• Demonstrated project management and execution skills with strong ability to manage deliverables and deadlines for multiple initiatives and teams• Proven skills in relationship management and managing multiple stakeholders with professionalism and maturity• Experience partnering with Financial Institutions• Superior executive-level written and oral communications skills• Excellent interpersonal skills and the ability to work cross-functionally• Results driver, with flexible "can do" perspective and strong interest in serving our customers• Strong analytical skills and financial acumen, with the ability to interpret complex data, assess business performance, and support decision-making across portfolios• Travel required - ~ 25%. Mastercard is a merit-based, inclusive, equal opportunity employer that considers applicants without regard to gender, gender identity, sexual orientation, race, ethnicity, disabled or veteran status, or any other characteristic protected by law. We hire the most qualified candidate for the role. In the US or Canada, if you require accommodations or assistance to complete the online application process or during the recruitment process, please contact reasonable_accommodation@mastercard.com and identify the type of accommodation or assistance you are requesting. Do not include any medical or health information in this email. The Reasonable Accommodations team will respond to your email promptly. Corporate Security Responsibility All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must: - Abide by Mastercard's security policies and practices; - Ensure the confidentiality and integrity of the information being accessed; - Report any suspected information security violation or breach, and - Complete all periodic mandatory security trainings in accordance with Mastercard's guidelines. In line with Mastercard's total compensation philosophy and assuming that the job will be performed in the US, the successful candidate will be offered a competitive base salary and may be eligible for an annual bonus or commissions depending on the role. The base salary offered may vary depending on multiple factors, including but not limited to location, job-related knowledge, skills, and experience. Mastercard benefits for full time (and certain part time) employees generally include: insurance (including medical, prescription drug, dental, vision, disability, life insurance); flexible spending account and health savings account; paid leaves (including 16 weeks of new parent leave and up to 20 days of bereavement leave); 80 hours of Paid Sick and Safe Time, 25 days of vacation time and 5 personal days, pro-rated based on date of hire; 10 annual paid U.S. observed holidays; 401k with a best-in-class company match; deferred compensation for eligible roles; fitness reimbursement or on-site fitness facilities; eligibility for tuition reimbursement; and many more. Mastercard benefits for interns generally include: 56 hours of Paid Sick and Safe Time; jury duty leave; and on-site fitness facilities in some locations. Pay Ranges Purchase, New York: $158,000 - $253,000 USD Arlington, Virginia: $158,000 - $253,000 USD New York City, New York: $164,000 - $264,000 USD O'Fallon, Missouri: $137,000 - $220,000 USD Remote - Delaware: $137,000 - $220,000 USD Remote - North Carolina: $137,000 - $220,000 USD Job Posting Window Posting windows may change based on the volume of applications received and business necessity. Candidates are encouraged to apply expeditiously.

Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we're helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Director, Consumer Debit, National Accounts Overview Our North America sales organization is seeking to build a diverse, strategic and consultative workforce of world-class relationship managers, problem-solvers, and technologists. We are looking for an Account Manager to join our team who can drive value for one of our largest, most strategic national issuers. The Director, Account Management role is a senior individual contributor responsible for driving strategy, revenue growth, financial performance, and execution for a large, complex Consumer Debit portfolio. The role serves as the primary client relationship owner on the Consumer Debit portfolio, accountable for outcomes and long-term strategic partnership development. This position drives portfolio and revenue growth through consultative sales leadership, portfolio and initiative expansion, and strategic account planning, while partnering closely with Product, Services, Finance, Analytics, and Technology to translate client priorities into scalable, enterprise solutions. Success in this role requires strong commercial judgment, excellent, executive-level communication skills, robust financial acumen, and the ability to lead high-impact initiatives across a matrixed organization. Responsibilities Account & Client Relationship Leadership• Own end-to-end strategy and execution for major portfolio-related initiatives, aligning Mastercard capabilities to client priorities and market dynamics.• Serve as the primary client portfolio relationship owner, leading commercial discussions, opportunity development, and long-term account growth strategies.• Act as a trusted advisor to key client stakeholders, delivering insight-driven recommendations that strengthen partnerships and portfolio performance. Financial & Commercial Ownership• Deliver consistent performance results across annual financial objectives, revenue targets, and portfolio goals.• Drive portfolio growth and profitability through consultative sales leadership, disciplined financial management, and identification of expansion opportunities within the existing client relationship.• Lead financial strategy and decision support for major commercial activities, including renewals, extensions, and new opportunities. Strategic Execution & Operational Leadership• Lead complex, cross-functional initiatives that address strategic or operational needs and enable sustainable portfolio optimization and growth.• Partner with internal teams to deliver integrated solutions that improve efficiency, scalability, and client outcomes.• Oversee planning and execution of strategic initiatives, managing risks, interdependencies, and trade-offs to ensure successful delivery. Cross-Functional Integration & Influence• Act as the central integrator across Product, Services, Finance, Analytics, and Technology to align strategy, execution, and delivery supporting the entire Consumer Debit portfolio.• Influence stakeholders driving alignment, accountability, and results across teams.• Proactively surface and resolve issues that could impact portfolio performance or client outcomes. Enterprise & Cross-Product Initiative Contribution• Advance the Bank's and Mastercard's priorities by supporting cross-product / cross-portfolio initiatives that drive performance, consistency, and scale across Consumer, SMB, and adjacent portfolios.• Contribute to the evolution of enterprise best practices by shaping operating models, portfolio management approaches, and scalable capabilities that can be applied across products and lines of business.• Act as a trusted partner across stakeholders, modeling a consultative, results-oriented approach that reflects Mastercard's values and reinforces a client-centric, enterprise mindset. Experience & Qualifications• Comprehensive experience executing and delivering innovative solutions, engagement initiatives and thought leadership related to Consumer Credit, Consumer Debit or Small Business portfolios• Demonstrated in-depth knowledge of MasterCard's core products with a focus on Consumer Credit, Consumer Debit or Small Business• Demonstrated project management and execution skills with strong ability to manage deliverables and deadlines for multiple initiatives and teams• Proven skills in relationship management and managing multiple stakeholders with professionalism and maturity• Experience partnering with Financial Institutions• Superior executive-level written and oral communications skills• Excellent interpersonal skills and the ability to work cross-functionally• Results driver, with flexible "can do" perspective and strong interest in serving our customers• Strong analytical skills and financial acumen, with the ability to interpret complex data, assess business performance, and support decision-making across portfolios• Travel required - ~ 25%. Mastercard is a merit-based, inclusive, equal opportunity employer that considers applicants without regard to gender, gender identity, sexual orientation, race, ethnicity, disabled or veteran status, or any other characteristic protected by law. We hire the most qualified candidate for the role. In the US or Canada, if you require accommodations or assistance to complete the online application process or during the recruitment process, please contact reasonable_accommodation@mastercard.com and identify the type of accommodation or assistance you are requesting. Do not include any medical or health information in this email. The Reasonable Accommodations team will respond to your email promptly. Corporate Security Responsibility All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must: - Abide by Mastercard's security policies and practices; - Ensure the confidentiality and integrity of the information being accessed; - Report any suspected information security violation or breach, and - Complete all periodic mandatory security trainings in accordance with Mastercard's guidelines. In line with Mastercard's total compensation philosophy and assuming that the job will be performed in the US, the successful candidate will be offered a competitive base salary and may be eligible for an annual bonus or commissions depending on the role. The base salary offered may vary depending on multiple factors, including but not limited to location, job-related knowledge, skills, and experience. Mastercard benefits for full time (and certain part time) employees generally include: insurance (including medical, prescription drug, dental, vision, disability, life insurance); flexible spending account and health savings account; paid leaves (including 16 weeks of new parent leave and up to 20 days of bereavement leave); 80 hours of Paid Sick and Safe Time, 25 days of vacation time and 5 personal days, pro-rated based on date of hire; 10 annual paid U.S. observed holidays; 401k with a best-in-class company match; deferred compensation for eligible roles; fitness reimbursement or on-site fitness facilities; eligibility for tuition reimbursement; and many more. Mastercard benefits for interns generally include: 56 hours of Paid Sick and Safe Time; jury duty leave; and on-site fitness facilities in some locations. Pay Ranges Purchase, New York: $158,000 - $253,000 USD Arlington, Virginia: $158,000 - $253,000 USD New York City, New York: $164,000 - $264,000 USD O'Fallon, Missouri: $137,000 - $220,000 USD Remote - Delaware: $137,000 - $220,000 USD Remote - North Carolina: $137,000 - $220,000 USD Job Posting Window Posting windows may change based on the volume of applications received and business necessity. Candidates are encouraged to apply expeditiously.

• Lead and manage the Rooms Division teams to deliver exceptional guest experiences. • Oversee daily operations of Front Office, Housekeeping, Laundry, and Guest Services departments. • Inventory management to include linen, pars, etc. • Ensure seamless interdepartmental communication and collaboration. • Monitor and respond to guest feedback, ensuring effective service recovery and continuous improvement. • Manage departmental budgets, labor productivity, and cost controls to meet or exceed financial targets. • Develop and implement strategies to elevate service quality and operational efficiency. • Recruit, train, mentor, and develop department leaders and team members. • Ensure compliance with all safety, hygiene, and brand standards. • Maintain a visible presence during peak guest periods to support the team and engage with guests. • Collaborate with other departments such as Sales, Engineering, and Food & Beverage to drive overall success.