About GitHub GitHub is the world’s leading platform for agentic software development — powered by Copilot to build, scale, and deliver secure software. Over 180 million developers, including more than 90% of the Fortune 100 companies, use GitHub to collaborate, and more than 77,000 organisations have adopted GitHub Copilot. Locations In this role you can work from Remote, United States Overview At GitHub, we are passionate about creating innovative solutions that enhance the developer experience for millions of people worldwide. As a Senior Design Engineer, you’ll work closely with designers, product managers, and engineers to shape the next generation of developer tools. Join us at this exciting time in our company’s journey, where your contributions will be essential in elevating our core experiences and driving GitHub toward a bold future! As a Senior Design Engineer at GitHub, you’ll focus on shaping and exploring UX patterns, pushing what’s possible with an AI. You’ll work hands-on with design primitives and open source systems, prototyping new concepts and experimenting with emerging front-end technologies. Collaborating closely with systems designers, engineers, and product managers, you’ll help build, iterate, and refine high-quality user experiences. Your curiosity and creativity drive you to explore new solutions, contribute to open source, and elevate design standards as you help define the future of GitHub’s products. Design Engineers at GitHub are expert individual contributors; they're given a lot of autonomy and trust to work on our most impactful design projects. For this specific role, you will report directly to the Senior Director, Core UX Design. Responsibilities - Collaboration & Planning: Work with your team and partners to estimate schedules, set priorities, and support product planning for ongoing projects. - Problem-Solving & Synthesis: Generate and iterate solutions for moderately complex product challenges by synthesizing user needs and business insights to improve product design. - Exploration & Prototyping: Rapidly explore and prototype interactive concepts, especially around emerging UX patterns and AI-ready design languages, moving fast to test ideas and learn what works. Experiment with design primitives and open source systems. - Front-End Craft & Adaptability: Deliver front-end experiences with a focus on quality and detail, adapting quickly to new technologies and approaches—even when all the answers aren’t clear. - Systems & Architecture: Support evolving and scaling design systems, contribute to robust information architecture, and help advance open source initiatives. - Design Systems Integration: Integrate and use design system components to deliver product consistency and alignment with company standards. - Communication: Collaborate and communicate clearly with cross-disciplinary teams throughout ideation, design, and development for inclusive and well-understood messaging. - Accessibility & Craft: Deliver accessible, high-quality visual and interaction designs from concept to completion, ensuring assets, flows, and animations support GitHub’s brand and principles. - Brand & Experience: Build and refine interactive experiences that fully reflect GitHub’s brand vision. Qualifications Required Qualifications: - 7+ years' experience in product or service design, - OR bachelor's degree in Industrial Design, Product Design, Human Computer Interaction, or related field AND 5+ years' experience in product or service design, - OR master's degree in Industrial Design, Product Design, Human Computer Interaction, or related field AND3+ years' experience in product or service design, - OR doctorate in Industrial Design, Product Design, Human Computer Interaction, or related field AND1+ year(s) experience in product or service design, - OR equivalent experience. Preferred Qualifications: - 8+ years of experience shipping products and/or delivering to customers as a result of an end-to-end design process - Knowledge of typical data center designs/architectures and be following industry design trends - Experience with performing complex business case analysis to justify technical decisions and present the justification to management in a high-level review - Engineering experience working in modern web development (e.g., React, CSS, HTML, JavaScript methodologies, etc.) - Experience with WCAG compliance and/or implementing accessibility best practices Compensation Range The base salary range for this job is USD $124,000.00 - USD $329,200.00 /Yr. These pay ranges are intended to cover roles based across the United States. An individual's base pay depends on various factors including geographical location and review of experience, knowledge, skills, abilities of the applicant. At GitHub certain roles are eligible for benefits and additional rewards, including annual bonus and stock. These rewards are allocated based on individual impact in role. In addition, certain roles also have the opportunity to earn sales incentives based on revenue or utilization, depending on the terms of the plan and the employee's role. GitHub values - Customer-obsessed - Ship to learn - Growth mindset - Own the outcome - Better together - Diverse and inclusive Manager fundamentals - Model - Coach - Care Leadership principles - Create clarity - Generate energy - Deliver success Who We Are GitHub is the world’s leading AI-powered developer platform with 150 million developers and counting. We’re also home to the biggest open-source community on earth (and 99% of the world’s software has open-source code in its DNA). Many of the apps and programs you use every day are built on GitHub. Our teams are dreamers, doers, and pioneers, leading the way in AI, driving humanitarian efforts around the globe, and even sending open source to Mars (and beyond!). At GitHub, our goal is to create the space you need to do your best work. We’re remote-first and offer competitive pay, generous learning and growth opportunities, and excellent benefits to support you, wherever you are—because we know that people flourish when they can work on their own terms. Join us, and let’s change the world, together. EEO Statement GitHub is made up of people from a wide variety of backgrounds and lifestyles. We embrace diversity and invite applications from people of all walks of life. We don't discriminate against employees or applicants based on gender identity or expression, sexual orientation, race, religion, age, national origin, citizenship, disability, pregnancy status, veteran status, or any other differences. Also, if you have a disability, please let us know if there's any way we can make the interview process better for you; we're happy to accommodate!

• Lead integration programs end-to-end for external clients — from discovery and estimation through SOW shaping, stakeholder alignment, and delivery KPIs (on-time, on-budget, CSAT). • Navigate the full relationship stack. Translate architecture trade-offs to executives, earn trust with engineering teams, and keep both sides aligned throughout delivery. • Anticipate risk early, communicate trade-offs clearly, and protect margin through change-order discipline — without damaging the relationship. • Own your calendar, your estimates, and your commitments. No one will chase you for updates. You surface risks before they surface you. • Lead technical design, implementation, and deployment of large-scale MuleSoft integration and API solutions (CloudHub 2.0, Runtime Fabric, Anypoint MQ, Flex Gateway, or on-prem). • Develop and maintain DataWeave scripts, Mule flows, and CI/CD pipelines (Azure DevOps, GitHub Actions, Jenkins). • Enforce architectural and security standards (RAML/OAS, OAuth2, JWT, TLS, encryption). • Monitor and optimize integrations for performance, scalability, and maintainability. • Lead discovery sessions, shape estimates, and contribute to SOW development — you are the technical voice in the room with the client. • Own delivery KPIs: on-time rate ≥90%, estimate variance ≤±15%, client satisfaction scores that earn repeat business. • Proactively communicate status, risks, and decisions — updates go out without being asked. • Build trusted relationships that make scope conversations easier, not harder. • Provide coaching and technical guidance to engineers; lead code reviews and process improvements. • Operate as a peer, not a manager — lift standards through quality of work and direct feedback. • You reach for your AI-enabled IDE, LLM-based assistants, and AI-powered static analysis before anything else.

Position Summary: The Start Up (SU) Lead is an expert in global site start-up activities and is accountable for the execution of the site start-up strategy and planning, including the management and coordination activities such as Core/Site document collection and approval, ICF customization and approval, IRB/EC and CA/ MoH submissions and delivery of quality IMP release packages. Will act as Subject Matter Expert for questions by other in-country members (SUSs, CRAs, CSSs or others) supporting site start-up activities, Trainer for less-experienced staff on site start-up activities and may be identified as Owner of country specific tools and guidance documents to increase knowledge share of country specific site start-up activities. Essential functions of the job include but are not limited to: - Manage the site start up process through development of an activation readiness strategy to enable oversight of site start up delivery. - Coordinate, develop and present critical path planning including IRB/EC & CA/ MoH Strategy, ICF Customization, Risk Mitigations, IMP Release Requirements and Contract Execution. - Collaborate and communicate with stakeholders to secure input for milestone planning, and alignment of operational goals to ensure timely delivery of site start up activities to allow on time activation. - Participate in client meetings to establish client expectations for delivery, communication, risk mitigation strategy, status reporting, and metrics related to site start up. - Partner closely with Functional Leaders and Site Start up Specialists to proactively identify any risks to delivery and develop and execute mitigations to remove risks to timelines. - Provide oversight to ensure accuracy and completeness of agreed tracking and systems are maintained in real time to allow analysis of progress metrics against targets/timelines at study, country, and site levels. - Responsible to co-ordinate translations for documents required for submissions. - Maintain communication with other key functions participating to country start up i.e., Feasibility, Clinical Operations, Project Management, Regulatory and Site Contracts management group on project specific status and deliverables. - Act as SME for collection and maintenance of site level critical path to IMP Release data points such as local IRB/Ethics Committee (EC) timelines, other required reviews to secure activation, site contracts and budget negotiation requirements that may be in place as well as other start up requirements for assigned country. - If needed, directly support country or site level activities start up activities. - Support development of country specific Country Start-up summary and process flow identifying timelines, risks, and success factors. - Support development and facilitation of training sessions to expand Country Start-up knowledge and act as Subject Matter Expert for queries. - Mentor staff on local study start-up regulations, submissions, internal procedures and SSDL. - Interact with clients in proposal activities, including slide development and client presentation as required. - Performs other duties as assigned by management. Qualifications: Minimum Required: - Bachelors degree in life sciences or related field, or Registered Nurse (RN) or equivalent combination of education, training, and experience. - 5 years or more in start up, ideally with SU Lead or PM experience in either a CRO or pharmaceutical/ biotech industry or equivalent, relevant experience and/or demonstrated competencies. - 2 years or more experience in project milestone management, managing resources, budgets and coordinating team activities. Other Required: - Demonstrated leadership experience in driving cross-functional activities - Excellent communication and organizational skills are essential. - Experience using computerized information systems, electronic spreadsheets, word processing and electronic mail required. - Fluency in English and for non-English speaking countries the local language of country where position based. - Experience using milestone tracking tools/systems Preferred: - Advanced degree in life sciences or related field Competencies: - Knowledge of Good Clinical Practice/ICH Guidelines and other applicable regulatory requirements. - Ability to follow task-specific procedures, be attentive to detail and place importance on accuracy of information. - Excellent organizational skills. - Ability to effectively interact with project team(s) and effectively communicate in English and the local language of the country where located. - Ability to work independently in a fast-paced environment with a sense of urgency to match the pace. - Must demonstrate excellent computer skills. - Excellent time management and prioritization skills to ensure deadlines are met. - Excellent communication, presentation, interpersonal skills, both written and spoken, with an ability to inform, influence, convince, and persuade. - Occasional travel may be required. Any data provided as a part of this application will be stored in accordance with our Privacy Policy. For CA applicants, please also refer to our CA Privacy Notice. Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law. If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at QuestionForHR@precisionmedicinegrp.com. It has come to our attention that some individuals or organizations are reaching out to job seekers and posing as potential employers presenting enticing employment offers. We want to emphasize that these offers are not associated with our company and may be fraudulent in nature. Please note that our organization will not extend a job offer without prior communication with our recruiting team, hiring managers and a formal interview process.

Position Summary: The Start Up (SU) Lead is an expert in global site start-up activities and is accountable for the execution of the site start-up strategy and planning, including the management and coordination activities such as Core/Site document collection and approval, ICF customization and approval, IRB/EC and CA/ MoH submissions and delivery of quality IMP release packages. Will act as Subject Matter Expert for questions by other in-country members (SUSs, CRAs, CSSs or others) supporting site start-up activities, Trainer for less-experienced staff on site start-up activities and may be identified as Owner of country specific tools and guidance documents to increase knowledge share of country specific site start-up activities. Essential functions of the job include but are not limited to: - Manage the site start up process through development of an activation readiness strategy to enable oversight of site start up delivery. - Coordinate, develop and present critical path planning including IRB/EC & CA/ MoH Strategy, ICF Customization, Risk Mitigations, IMP Release Requirements and Contract Execution. - Collaborate and communicate with stakeholders to secure input for milestone planning, and alignment of operational goals to ensure timely delivery of site start up activities to allow on time activation. - Participate in client meetings to establish client expectations for delivery, communication, risk mitigation strategy, status reporting, and metrics related to site start up. - Partner closely with Functional Leaders and Site Start up Specialists to proactively identify any risks to delivery and develop and execute mitigations to remove risks to timelines. - Provide oversight to ensure accuracy and completeness of agreed tracking and systems are maintained in real time to allow analysis of progress metrics against targets/timelines at study, country, and site levels. - Responsible to co-ordinate translations for documents required for submissions. - Maintain communication with other key functions participating to country start up i.e., Feasibility, Clinical Operations, Project Management, Regulatory and Site Contracts management group on project specific status and deliverables. - Act as SME for collection and maintenance of site level critical path to IMP Release data points such as local IRB/Ethics Committee (EC) timelines, other required reviews to secure activation, site contracts and budget negotiation requirements that may be in place as well as other start up requirements for assigned country. - If needed, directly support country or site level activities start up activities. - Support development of country specific Country Start-up summary and process flow identifying timelines, risks, and success factors. - Support development and facilitation of training sessions to expand Country Start-up knowledge and act as Subject Matter Expert for queries. - Mentor staff on local study start-up regulations, submissions, internal procedures and SSDL. - Interact with clients in proposal activities, including slide development and client presentation as required. - Performs other duties as assigned by management. Qualifications: Minimum Required: - Bachelors degree in life sciences or related field, or Registered Nurse (RN) or equivalent combination of education, training, and experience. - 5 years or more in start up, ideally with SU Lead or PM experience in either a CRO or pharmaceutical/ biotech industry or equivalent, relevant experience and/or demonstrated competencies. - 2 years or more experience in project milestone management, managing resources, budgets and coordinating team activities. Other Required: - Demonstrated leadership experience in driving cross-functional activities - Excellent communication and organizational skills are essential. - Experience using computerized information systems, electronic spreadsheets, word processing and electronic mail required. - Fluency in English and for non-English speaking countries the local language of country where position based. - Experience using milestone tracking tools/systems Preferred: - Advanced degree in life sciences or related field Competencies: - Knowledge of Good Clinical Practice/ICH Guidelines and other applicable regulatory requirements. - Ability to follow task-specific procedures, be attentive to detail and place importance on accuracy of information. - Excellent organizational skills. - Ability to effectively interact with project team(s) and effectively communicate in English and the local language of the country where located. - Ability to work independently in a fast-paced environment with a sense of urgency to match the pace. - Must demonstrate excellent computer skills. - Excellent time management and prioritization skills to ensure deadlines are met. - Excellent communication, presentation, interpersonal skills, both written and spoken, with an ability to inform, influence, convince, and persuade. - Occasional travel may be required. Any data provided as a part of this application will be stored in accordance with our Privacy Policy. For CA applicants, please also refer to our CA Privacy Notice. Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law. If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at QuestionForHR@precisionmedicinegrp.com. It has come to our attention that some individuals or organizations are reaching out to job seekers and posing as potential employers presenting enticing employment offers. We want to emphasize that these offers are not associated with our company and may be fraudulent in nature. Please note that our organization will not extend a job offer without prior communication with our recruiting team, hiring managers and a formal interview process.