Overview Position: Scientific Director Of Oligonucleotide Drug Discovery Work Location: United States (Remote/Home-Based) Position Overview: We are seeking a strategic scientific leader to drive our Oligonucleotide Drug Discovery platform. This individual will focus on scientific strategy, client engagement, and program communication, acting as a key scientific voice and partner both internally and externally. The role requires deep expertise in Oligonucleotide Drug Discovery, and the ability to translate science into business growth. Responsibilities - Develop and implement strategic plans to advance the oligonucleotide drug discovery platform. - Build and maintain strong client relationships, understand their scientific needs, and ensure high levels of customer satisfaction. - Provide scientific leadership and guidance across projects, fostering innovation and ensuring scientific rigor. - Monitor emerging scientific trends and breakthroughs in oligonucleotide therapeutics, and recommend new capabilities or approaches. - Collaborate closely with cross-functional teams and senior management to align strategies and create synergies across the organization. - Support BD and marketing efforts through scientific presentations, client meetings, and contributions to proposals and marketing materials. - Ensure clear and effective communication of program updates, data, and scientific insights to clients and internal stakeholders. Qualifications - PhD. in biology or a relevant major with 6+ years of working experience in oligonucleotide drug discovery or related researches in industrial or academic institutes. Experience in siRNA or ASO focused industrial company is preferred.. - Comprehensive knowledge of the discovery of various oligonucleotide drugs, especially ASO and siRNA, including drug design, chemical modification, delivery system, in vitro and in vivo evaluations, ADME/PK and toxicology, bioanalysis, bioinformatics for oligonucleotide agents. - Familiar with the discovery and development of therapeutic oligonucleotides, especially ASO and siRNA agents. - A proven track record of scientific publications on ASO, siRNA, mRNA or other RNA drug discovery. - High motivation to embrace new technologies and tools. - Excellent written and oral communication skills in English, with the ability to engage effectively with clients and internal teams. - Proven ability to work collaboratively in a matrixed environment and support business growth through scientific excellence. - Strategic mindset with experience in client-facing

Oversee operational strategies and team growth while managing project efficiency and financial performance. Establish metrics for improvement and maintain strong business processes to ensure quality and timely project delivery.

Title: Senior Director, Immunology, Cardiovascular, & Neuroscience, Medical Evidence Generation Location: Princeton - NJ - US Madison - Giralda - NJ - US time type Full time job requisition id R1600692 Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. This Senior Director, Immunology, Cardiovascular, & Neuroscience (I, CV, & N), Medical Evidence Generation (MEG) role in Global Medical Affairs manages the evidence generation for the I, CV, & N portfolio (including Medical Affairs Sponsored studies [MAST], Clinical Research Collaborations [CRC], and investigator-sponsored studies [ISR]) and provides leadership for the cross-functional teams executing on the book of work. In this role, he/she will have a key role in ensuring the strategic data generation needs for the I,CV,&N organization are executed with speed and rigor. The I,CV,&N Senior Director will lead and participate in cross-functional matrix leadership teams focused on building these relationships and actively sourcing research concepts that address critical evidence gaps for early and late assets being developed in prioritized indications. The Senior Director reports to the Immunology, Cardiovascular, & Neuroscience (I,CV,&N) Vice President. Responsibilities include: - Build, manage, and coach for sustained high performance an externally focused global team accountable for defining and executing the I,CV,&N portfolio to address key data gaps. - Coach a team of MEG Leads, inclusive of Clinical Scientists and Clinical Trial Physicians, in successful oversight of Medical clinical trials end-to-end (i.e., start-up, influence governance outcomes, partner with contract Manager/Lead for agreement initiation, negotiation, and execution, oversight throughout study and support readout). - Design and drive strategies to successfully identify and advance new medical trials that accelerate the development of the BMS pipeline. - Should have experience in clinical concept development and partnering across the drug development continuum. - Project leadership, managing cross functional team members focused on scientific aspects (including results) and other study-related activities as appropriate. - Contribute to the evolution of the MEG organizational model and operational infrastructure. - Accountable for the I,CV,&N MEG book of work (including but not limited to MASTs, ISRs, CRCs, and IEP development) ensuring they are in alignment with the Integrated Evidence Plan (IEP), and executed with rigor and on time - Provide accountability and oversight for the authoring and development of the medical study protocol and ICF, providing medical input during protocol development to ensure clinical relevance, scientific rigor, patient safety, and alignment with study objectives. - Accountable for ensuring scientific integrity and data quality is maintained during executions of medical trial, ensuring quality execution of deliverables for all phases (start-up/conduct/closure). - Lead the team responsible for the co-development and maintenance of the IEPs, in partnership with Medical, HEOR, Development and other key internal stakeholders. - Partner closely with key stakeholders across Medical Affairs and Drug Development working on the I,CV,&N portfolio to ensure cohesiveness and one MEG voice. - Employ strong business acumen and fiscal stewardship focused on driving reciprocal scientific value creation and allocating resources consistent with company priorities. - Assist in reviews of concepts through RFP process, including providing context for ongoing book of work, area of interest development, and upcoming data read outs. Qualifications & Experience - MD preferred (or x-US equivalent). - 5+ years required clinical trial experience in pharmaceutical industry setting (e.g., Clinical Trial Physician, Clinical Scientist); expertise in drug development process and clinical research; with demonstrated proficiency in driving and managing company-sponsored clinical trials and leading teams. - 5+ years preferred strategic leadership experience in a pharmaceutical industry setting and possessing an in-depth understanding of clinical and business development, Medical Affairs, and Commercial functions related to the drug development process. - 10+ years of experience preferred in clinical science, clinical research, or equivalent. - Exhibits confidence and professional diplomacy, while effectively relating to people at all levels internally and externally. - Promotes a culture of scientific excellence, multidisciplinary problem solving, teamwork, consistency, flexibility, execution, quality, and effective communication. - Adeptness at building credibility with external investigators and collaborative partners competently balancing business and scientific acumen complemented by strong leadership behaviors, authenticity, agility, and an enterprise mindset. - Demonstrated ability to develop and sustain a high-performing team along with a proven ability to successfully lead teams (including matrix colleagues). - Demonstrated track record of leadership in a complex, matrix environment. - Exceptional communication and interpersonal skills to influence decision-making at all levels of the organization. This Position is preferably based at the Princeton Pike (PPK) site in Lawrenceville, NJ; Expected travel ~20%-30% globally. #LI-HYBRID If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview: Madison - Giralda - NJ - US: $229,380 - $277,956 Princeton - NJ - US: $229,380 - $277,956 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include: - Health Coverage: Medical, pharmacy, dental, and vision care. - Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). - Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. Work-life benefits include: Paid Time Off - US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) - Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. - Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. Supporting People with Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application. Candidate Rights BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Data Protection We will never request payments, financial information, or social security numbers during our application or recruitment process. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley. R1600692 : Senior Director, Immunology, Cardiovascular, & Neuroscience, Medical Evidence Generation

• Develop strategy, brand platforms, integrated campaigns, broadcast spots, web content, social, launch films, product and educational films • Produce work that is smart, strategic and beautifully crafted for a wide range of brands • Engage in ideation, production, design, creative processes, and workflows • Collaborate with a tight-knit team to make great work