Our Mission Our passion for improving patients’ lives motivates us to apply our skills, experience and knowledge to advance medicine. We achieve this through flexible, innovative, high-quality solutions for our clients, delivered with integrity. The Role We are looking for an Associate Medical Director to join our Medical - Clinical Development team, where you will assume medical responsibility for clinical studies conducted by Simbec-Orion and is responsible for the clinical interpretation of data and to ensure clinical trials are conducted such that subjects' rights, safety and wellbeing are protected and that the clinical trial data are reliable. Assists in cross-departmental medical monitoring activities and works with the wider cross-functional team that include Clinical Operations, Project Management, Pharmacovigilance, Business Development, Biometrics and Regulatory and Technical Writing. Key Accountabilities - Acts as Medical Monitor for more complex trials. - Participates in all stages of the Clinical Trial Development process, e.g., feasibility assessments, protocol design, case report form design, investigational site selection, medical monitoring plan development, ongoing medical support, management of AE's and SAE's, and involvement in trial-related meetings. - Responds to study specific audit queries and supports in the resolution of the audit findings. - Supports the Medical Director in resolving general department CAPAs, escalations and cascading any audit findings to the study team during monthly department meetings. - Generation of protocol and synopsis writing with sponsor and Technical Writing team. - Review Clinical Study report and provides feedback to the Medical and Technical Writing team. - Generates Medical and Patient narratives and safety update reports. - Provide therapeutic area support throughout the organisation, including the provision of required internal training and review of study/bid proposals. - Maintain knowledge of trends and changes of importance in the medical management of indications, regulations and guidelines relevant to Simbec-Orion's projects. - Develops interactions with Key Opinion Leaders and investigators in therapeutic areas of interest to Simbec-Orion as a resource of specific information on indications, patient treatment, and safety assessment for ongoing studies and support business development activities. - Supports the Pharmacovigilance department in reviewing ICSRs, CIOMS narratives, and periodic safety reports and identifies and communicates emergent safety aspects and trends to the Clinical Project Teams and client. - Ensures that Clinical Trials conducted by Simbec-Orion meet the relevant regulations and guidelines and are conducted to the highest ethical standards. - Supports the development of Standard Operating Procedures to drive best practice across the Medical Department. - Interprets Clinical and Pharmacovigilance data (including the coding of clinical data and the review of relevant safety reports) to identify any potential safety concerns and advise the study team accordingly. - Supports in business development activities, e,g, proposal requests, feasibility and site contact, and attendance at bid defence meetings. - Supports the study team in reviewing audit findings that require medical input and communicates to the Head of the Department to apply corrective and preventive actions. Skills Required ESSENTIAL - Medical Degree - Background in Dermatology or Neurology, with demonstrable clinical experience in one of these therapeutic areas - Experience in medical monitoring, review of patient, laboratory, and safety within a clinical research environment - Experience in business development activities, including feasibility and strategic advice for proposal development and bid-defence meetings - Excellent organisation and time management skills. Ability to effectively manage any changes to priorities/deadlines - Experience in Regulatory and sponsor audit and resolving CAPAs. - Experience in Pharmacovigilance process, including medical review. - Professional communication and presentation skills - Strong computer skills including but not limited to the knowledge of electronic data capturing systems and MS-Office products such as Excel and Word DESIRABLE - GMC Registered with a License to Practice - Post-graduate Qualification in Clinical Pharmacology / Pharmaceutical Medicine - Previous experience of working within a small/mid-size CRO, biotech or pharmaceutical company - Proven experience in building effective relationships with external clients and sponsors About Us Simbec-Orion is a responsive and agile full-service CRO, delivering studies from first in man through to Phase III. Our experts leverage wide therapeutic experience and specialist expertise to execute a comprehensive portfolio of trials. We are perfectly structured to provide full-service clinical development solutions for small and mid-size drug developers, headed up by a centralised leadership team. With a focus on tailormade and scalable solutions, we adapt our delivery style, communications and operations to suit the demands of the project, helping clients achieve their clinical and commercial objectives. Because our goal is the same as theirs; to improve patients’ lives.

• Provides clinical oversight and utilization management for Home Health, Durable Medical Equipment (DME), Home Infusion Therapy, Sleep Medicine, and related services. • Conducts medical necessity reviews using industry-standard clinical criteria and evidence-based guidelines to support coverage determinations and quality care outcomes. • Conducts efficient medical necessity reviews and peer to peer consultations in adherence with regulatory and compliance turnaround times on cases that may not meet clinical criteria. • Issues adverse determinations as needed. • Provides guidance to licensed and non-licensed associates on clinical issues and case reviews related to authorization requests and clinical guidelines criteria. • Completes peer to peer discussions when medical necessity criteria are not met. • Participates in CareCentrix Care Coordination, Utilization Management, Quality Improvement and clinical education activities, as requested. • Utilizes clinical integrity in all determinations and interactions with internal and external partners. • Collaborates with Health Plan clinical leadership as requested. • Achieves Service Level Agreement (SLA) metrics and performance guarantees as required by health plan clients. • Participates and supports different committees and clinical rounds as necessary or assigned.

Job title: Associate Director Commercial Excellence, US Vaccines - Location: Remote, US About the Job: As an Associate Director Commercial Excellence, US Vaccines for the Sanofi Vaccines Team, you are a leader with excellent influential leadership and business acumen skills. You are known for your ability to identify and exploit business opportunities with a great focus on developing and execution of sustainable business plans. You are a strong cross-functional collaborator with high accountability in helping your region drive peak performance. Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization. About Sanofi We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. Main Responsibilities - Operational excellence and strategic support to ensure seamless execution of product and portfolio sales strategy - Support Regional General Managers and Head of Commercial Excellence by regularly reviewing key upcoming business updates, daily meetings, and major focus projects to determine any preparations needed, deliverables, planning or preliminary stakeholder engagement follow-ups to ensure level of readiness for each key meeting and /or business update - Lead and coordinate the national and regional level business planning process and business review process. This includes identifying and holding the matrix team accountable to local Critical Business Priorities - Partner with GTMC to continuously improve insights and analytics needs and advancing our integrated omnichannel approach - Pull and analyze call activity data and deliver on ad hoc analyses when required - Develop and lead National implementation of brand/marketing strategies. (i.e., account initiatives, POA, field-based tactics) - Support and drive the project management of special projects as determined by the needs of the key priorities within the organization - Embed new ways of working/ elevate execution - Define and drive the collaborative & effective ways of working between field sales and account management - Lead national pull through initiative efforts and monitor plan for success - Develop insights on regional performance trends leveraging consistent KPI’s in concert with the head of sales, head of commercial excellence, and regional sales directors ensure metrics are being met - Identify and share best practices to multiply usage and implementation across nation/ enhance execution/ drive impact - Support business operations excellence - Drive Sales Force Effectiveness through 1:1’s dialogues with Field Leadership intended to identify specific local performance gaps and drivers - Responsible for supporting on operations and execution of POA meetings and other relevant sales meetings About You: Basic Qualifications: - BA/BS from an accredited school required. - 3+ years of successful cross-functional experience with home office / operations / sales / commercial excellence expertise - Ability to influence without authority a matrix team consisting of Sales, BO&S, digital, and Marketing members. - Ability to work internally with home office - Experience leading or working on multi – level operational plans or key projects - Proficiency in understanding sales and marketing strategy, and demonstrates ability to deliver support and solutions - An inspiring change agent mindset who is willing to challenge the status quo and align others to help drive business transformation - Strategic and analytic skills with the ability to translate complex data sets into action plans. - Possess effective communication and change agility skills - Ability to travel to Home Office and key sales meetings Preferred Qualifications: - Focus on business, life sciences or public health preferred. - 3+ years of successful field leadership experience with home office / operations / commercial excellence experience preferred - Experience in both marketing and a sales related function - Leader in an ever-evolving environment, with demonstrated use of change management strategies/tactics to influence new ways of thinking and working - Manages conflict with composure and demonstrates managerial courage - Embodies Sanofi’s Take the Lead behaviors to support a cultural transformation Why Choose Us? - Bring the miracles of science to life alongside a supportive, future-focused team. - Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. - Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. - Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. - Work at the forefront of AI-driven research, smart manufacturing, and groundbreaking mRNA platforms that are redefining the future of immunology. - Help protect half a billion people every year, contributing to one of the largest global vaccination efforts in healthcare. - Develop your career with access to mentoring, international mobility programs, and opportunities to grow across four continents. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SP #LI-SP #LI-Remote #vhd Pursue progress, discover extraordinary Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com! US and Puerto Rico Residents Only Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. North America Applicants Only The salary range for this position is: $133.500,00 - $192.833,33 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.

Job title: Associate Director Commercial Excellence, US Vaccines - Location: Remote, US About the Job: As an Associate Director Commercial Excellence, US Vaccines for the Sanofi Vaccines Team, you are a leader with excellent influential leadership and business acumen skills. You are known for your ability to identify and exploit business opportunities with a great focus on developing and execution of sustainable business plans. You are a strong cross-functional collaborator with high accountability in helping your region drive peak performance. Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization. About Sanofi We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. Main Responsibilities - Operational excellence and strategic support to ensure seamless execution of product and portfolio sales strategy - Support Regional General Managers and Head of Commercial Excellence by regularly reviewing key upcoming business updates, daily meetings, and major focus projects to determine any preparations needed, deliverables, planning or preliminary stakeholder engagement follow-ups to ensure level of readiness for each key meeting and /or business update - Lead and coordinate the national and regional level business planning process and business review process. This includes identifying and holding the matrix team accountable to local Critical Business Priorities - Partner with GTMC to continuously improve insights and analytics needs and advancing our integrated omnichannel approach - Pull and analyze call activity data and deliver on ad hoc analyses when required - Develop and lead National implementation of brand/marketing strategies. (i.e., account initiatives, POA, field-based tactics) - Support and drive the project management of special projects as determined by the needs of the key priorities within the organization - Embed new ways of working/ elevate execution - Define and drive the collaborative & effective ways of working between field sales and account management - Lead national pull through initiative efforts and monitor plan for success - Develop insights on regional performance trends leveraging consistent KPI’s in concert with the head of sales, head of commercial excellence, and regional sales directors ensure metrics are being met - Identify and share best practices to multiply usage and implementation across nation/ enhance execution/ drive impact - Support business operations excellence - Drive Sales Force Effectiveness through 1:1’s dialogues with Field Leadership intended to identify specific local performance gaps and drivers - Responsible for supporting on operations and execution of POA meetings and other relevant sales meetings About You Basic Qualifications: - BA/BS from an accredited school required. - 3+ years of successful cross-functional experience with home office / operations / sales / commercial excellence expertise - Ability to influence without authority a matrix team consisting of Sales, BO&S, digital, and Marketing members. - Ability to work internally with home office - Experience leading or working on multi – level operational plans or key projects - Proficiency in understanding sales and marketing strategy, and demonstrates ability to deliver support and solutions - An inspiring change agent mindset who is willing to challenge the status quo and align others to help drive business transformation - Strategic and analytic skills with the ability to translate complex data sets into action plans. - Possess effective communication and change agility skills - Ability to travel to Home Office and key sales meetings Preferred Qualifications: - Focus on business, life sciences or public health preferred. - 3+ years of successful field leadership experience with home office / operations / commercial excellence experience preferred - Experience in both marketing and a sales related function - Leader in an ever-evolving environment, with demonstrated use of change management strategies/tactics to influence new ways of thinking and working - Manages conflict with composure and demonstrates managerial courage - Embodies Sanofi’s Take the Lead behaviors to support a cultural transformation Why Choose Us? - Bring the miracles of science to life alongside a supportive, future-focused team. - Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. - Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. - Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. - Work at the forefront of AI-driven research, smart manufacturing, and groundbreaking mRNA platforms that are redefining the future of immunology. - Help protect half a billion people every year, contributing to one of the largest global vaccination efforts in healthcare. - Develop your career with access to mentoring, international mobility programs, and opportunities to grow across four continents. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SP #LI-SP #LI-Remote #vhd Pursue progress, discover extraordinary Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com! US and Puerto Rico Residents Only Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. North America Applicants Only The salary range for this position is: $133.500,00 - $192.833,33 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.