• Generate SDTM, ADaM specifications, datasets, reviewer’s guide and define.xml files for multiple studies • Develop SAS programs which generate datasets, complex listings, tables (including those with descriptive and standard inferential statistics in collaboration with a Statistician), and complex graphs • Deliver high-quality statistical programming results including developing, validating, and maintaining SAS and/or R programs tailored to clinical development programs’ needs • Participate in overseeing CRO’s statistical programming deliverables for multiple clinical studies to ensure high-quality and meet the pre-specified timelines • Support the preparation of clinical study reports, regulatory submissions, publications, annual DSUR, and exploratory analyses • Understand and follow FDA regulations which affect the reporting of clinical trial data. This includes good clinical practice and guidelines for electronic submissions. • Contribute to the creation, maintenance, documentation, and validation of standards for programming tools, outputs, and macros • Participate in the development of CRFs, edit check specifications, and data validation plans • Provide review and/or author data transfer specifications for external vendor data • Collaborate with internal and external functions (e.g. CROs, software vendors, clinical development partners, etc.) to ensure meeting project timelines and goals • Provide review and/or author SOPs and/or Work Instructions related to statistical programming practices

Role Description Nous souhaitons renforcer notre capacité à concevoir, développer et maintenir des solutions internes et clients performantes et durables. Votre mission en tant que Lead Developer s’articule autour de trois grandes responsabilités : - Technique : - Garantir la qualité et la cohérence de l’architecture - Prendre les décisions technologiques structurantes - Maintenir les standards de code et anticiper la dette technique - Participer au développement - Humain : - Encadrer et faire monter en compétences les développeurs - Faciliter la collaboration au sein de l’équipe - Être un point de référence et débloquer les situations complexes - Stratégique : - Faire le pont entre le métier/product et l’équipe technique - Prioriser les efforts et challenger les besoins afin d’éviter la sur-ingénierie Au sein de notre département SI, rattaché(e) au pôle applicatif, le rôle de Lead Developer est central dans cette dynamique. Vous contribuerez directement à structurer nos pratiques de développement, à assurer la qualité technique de nos applications et à guider les choix technologiques sur des projets stratégiques. Ce poste intervient dans un contexte où la standardisation des pratiques et la montée en compétence de l’équipe sont des enjeux clés. Vous travaillerez en étroite collaboration avec : - Les équipes de développement et les QA (testeurs) - Les Product Owners - Les équipes IT infrastructure - Les interlocuteurs métiers Qualifications - Formation supérieure en école d’Ingénieur en informatique (EPITA, EPITECH, EFREI, etc.) ou équivalent - Expérience significative en développement et en architecture technique - Compétences techniques : C#, Angular, SQL Server, NoSQL, Azure, Terraform - Maîtrise des bonnes pratiques de développement et de la méthodologie Agile (Scrum) - Expérience avec Azure DevOps - Capacités à communiquer, documenter et à transmettre ses connaissances - Rigueur, autonomie, esprit d’initiative, travail en équipe et sens de l’innovation - Leadership naturel : capacité à fédérer une équipe, à prendre des décisions avec clarté et à embarquer les autres dans une vision technique commune - La méthodologie SAFe serait un plus Requirements - Accompagner et conseiller sur le choix des solutions technologiques à mettre en œuvre - Participer à la conception, à l’architecture et aux études de faisabilité - Assurer une veille technologique sur les langages, architectures, cloud, sécurité - Développer et maintenir les outils et solutions selon la feuille de route - Garantir la qualité du code, le respect des bonnes pratiques (tests, performance, sécurité) et l’IaC (Infrastructure as Code) - Mettre en place et améliorer les environnements et outils de développement - Participer aux tests, UAT et support Niveau 3 - Accompagner, guider et faire monter en compétence les développeurs - Favoriser le partage de connaissances et l’esprit d’équipe - Animer des présentations techniques et de l’évangélisation sur nos outils - Travailler dans un contexte Agile (Scrum) avec intégration continue - Documenter les applications et rédiger les dossiers techniques - Détecter et résoudre les problèmes de communication et de coordination dans l’équipe Benefits - Un rôle clé dans l’amélioration et la structuration des pratiques techniques - La possibilité de piloter des choix technologiques stratégiques - Un impact direct sur la qualité, la performance et l’innovation des solutions - Un environnement Agile où le test, l’apprentissage et l’autonomie sont encouragés

Intersog® is a Chicago-based provider of tailored software engineering solutions, offering dedicated development teams and custom software applications to help businesses meet their IT challenges. Our focus on innovation and efficiency allows us to partner effectively with clients across various industries. We are looking for a talented Java Software Engineer (BackEnd). Our client is looking to transform experiments into executable instructions for Workcells and devices. This is why we are looking for a dynamic Software Engineer to join our team. You will collaborate with a talented team of engineers and with cross-functional departments to deliver high-quality solutions that meet our clients' needs. If you're passionate about technology and creating user-centric applications, we want to hear from you! Responsibilities: - Java Backend Service Development: Design, develop, and maintain scalable and resilient Java-based Kubernetes services using the Spring Boot framework and its code generation capabilities. Leverage Spring's robust features, such as dependency injection, data access, and web development, to build efficient and maintainable microservices. - Microservices Architecture: Design and implement new microservices, and enhance existing ones, adhering to best practices of microservices architecture. This entails utilizing message-based communication systems and effectively leveraging SDK clients or APIs for inter-service interaction. Additionally, employ efficient data querying techniques to retrieve information from diverse data systems and ensure transactional data integrity to ensure no instruction is lost. - Akka Actors and Distributed Systems: Design, Build, and test execution logic partitioned by akka actors. Develop new distributed systems designs as needed to support the volume of experiment requests in a laboratory. - Constraint Solvers: The core capability of the Orchestration Layer is solving a scheduling problem. The scheduling problem is created by an input experiment and the available inventory in a target laboratory. Choose the best algorithms and frameworks for the experiment request volume and the quantity of workcells and devices present in our client laboratories. - Execution Engine: Computing the execution plan for an input experiment is the first half of the Orchestration Layer. The second half is managing the execution of said plan. Design, Build, and test the execution engine in the Orchestration Layer. - Workcell Software Expertise: Gain a deep knowledge of the execution models and access patterns for Workcell Software Systems. The Orchestration Layer does not communicate directly with Workcell Software Systems but must generate execution plans and execute them in accordance with the current capabilities of Workcell Software Systems.

About GitHub GitHub is the world’s leading platform for agentic software development — powered by Copilot to build, scale, and deliver secure software. Over 180 million developers, including more than 90% of the Fortune 100 companies, use GitHub to collaborate, and more than 77,000 organisations have adopted GitHub Copilot. Locations In this role you can work from Remote, United Kingdom Overview GitHub is the home for software development, where we collaborate to build the world's leading AI-powered developer platform. In the Copilot Agents organization at GitHub, we are passionate about ensuring the security and quality of the world’s software - from open source to the enterprise, written by humans and by AI tools. We believe that the best way to secure and improve the quality of software is to detect actionable issues early in the development process, and actively facilitate their remediation as part of the developer workflow. Our team develops detection and remediation engines that power several GitHub products used by hundreds of thousands of developers and projects every day: - Copilot Code Review agent is GitHub LLM-powered code review engine which provides feedback for immense volumes of code changes daily helping developers fix bugs and improve the quality of their code, leading to faster time to merge. - Copilot Autofix is GitHub's LLM-powered remediation engine that produces high-quality fix suggestions for security or quality findings, empowering developers to fix them as soon as they are found or burn down the debt already existing in their codebase. It is used as the remediation engine within the GitHub Code Security, GitHub Advanced Security, and Copilot code review products. - CodeQL is GitHub's semantic code analysis engine that uses world-class static analysis research and technology to deeply analyze code, enabling the early detection of security vulnerabilities and correctness errors in software. CodeQL supports a wide range of programming languages, including C/C++, C#, Go, Java, JavaScript/TypeScript, Kotlin, Python, Ruby, and Swift. It is used as the primary detection engine within the GitHub Code Security and GitHub Advanced Security products. We work as a distributed group within a distributed company. The majority of our team members live across Europe, the US, and Canada, and while we do have some offices, all our meetings are location-agnostic and happen online. We operate with a high degree of autonomy and trust, and we have a significant level of influence on the product and technical direction of security and code review products at GitHub. We value learning, introspection and reflection, and we’re always looking for ways to improve as a team and as individuals, so candor and a culture that values safety to speak up are highly important to us. Responsibilities We are looking for a Senior Software Engineer to join one of the distributed software engineering teams responsible for building and expanding code analysis engines and agents at GitHub. You will work closely with various engineering teams, product managers, designers, and technical writers that build different aspects of the products, to influence product direction and deliver features to users, with clear focus on quality, reliability, and user experience. You will engage with internal users and external users (both from enterprise customers and the open-source community) to help them succeed with the product. You’ll influence and provide feedback on the organizational culture and processes, always looking for opportunities to improve in a continuous pursuit of excellence. Qualifications Required Qualifications: For this role, we’re looking for an experienced software engineer with: - 6+ years experience in Software Engineering, Computer Science, or related technical discipline with proven experience maintaining and delivering production software coding in languages including, but not limited to, C, C++, C#, Java, JavaScript/TypeScript, Go, Ruby, Rust, or Python. - OR Associate’s Degree in Computer Science, Electrical Engineering, Electronics Engineering, Math, Physics, Computer Engineering, or related field AND 5+ years experience in Software Engineering, Computer Science, or related technical discipline with proven experience maintaining and delivering production software coding in languages including, but not limited to, C, C++, C#, Java, JavaScript/TypeScript, Go, Ruby, Rust, or Python. - OR Bachelor's Degree in Computer Science, Electrical Engineering, Electronics Engineering, Math, Physics, Computer Engineering, or related field AND 4+ years experience in Software Engineering, Computer Science, or related technical discipline with proven experience maintaining and delivering production software coding in languages including, but not limited to, C, C++, C#, Java, JavaScript/TypeScript, Go, Ruby, Rust, or Python - OR Master's Degree in Computer Science, Electrical Engineering, Electronics Engineering, Math, Physics, Computer Engineering, or related field AND 2+ years experience in Software Engineering, Computer Science, or related technical discipline with proven experience maintaining and delivering production software coding in languages including, but not limited to, C, C++, C#, Java, JavaScript/TypeScript, Go, Ruby, Rust, or Python. - OR Doctorate in Computer Science, Electrical Engineering, Electronics Engineering, Math, Physics, Computer Engineering, or related field. - OR equivalent experience. - 3+ years of experience with one or more of the following areas: - Experience building developer tools that operate on source code, such as compilers, parsers, linters, static analyzers, debuggers, CLI tools, or IDE extensions. - OR Machine learning and AI applied to understanding source code, specifically building systems that use large language models (LLMs) to generate or reason about code, and systematic benchmarking and evaluation of those systems. Preferred qualifications: Additionally, we would highly encourage applying if you have one or more of the following skills: - Experience with both of the areas listed above - Experience designing and running statistically-sound experiments to measure performance and quality, evaluating results to minimize bias and noise. - Experience with code security analysis - Industry or research knowledge of compilers, program analysis, programming language design and implementation. GitHub values - Customer-obsessed - Ship to learn - Growth mindset - Own the outcome - Better together - Diverse and inclusive Manager fundamentals - Model - Coach - Care Leadership principles - Create clarity - Generate energy - Deliver success Who We Are GitHub is the world’s leading AI-powered developer platform with 150 million developers and counting. We’re also home to the biggest open-source community on earth (and 99% of the world’s software has open-source code in its DNA). Many of the apps and programs you use every day are built on GitHub. Our teams are dreamers, doers, and pioneers, leading the way in AI, driving humanitarian efforts around the globe, and even sending open source to Mars (and beyond!). At GitHub, our goal is to create the space you need to do your best work. We’re remote-first and offer competitive pay, generous learning and growth opportunities, and excellent benefits to support you, wherever you are—because we know that people flourish when they can work on their own terms. Join us, and let’s change the world, together. Equal Employment Opportunity GitHub is made up of people from a wide variety of backgrounds and lifestyles. We embrace diversity and invite applications from people of all walks of life. We don't discriminate against employees or applicants based on gender identity or expression, sexual orientation, race, religion, age, national origin, citizenship, disability, pregnancy status, veteran status, or any other differences. Also, if you have a disability, please let us know if there's any way we can make the interview process better for you; we're happy to accommodate!