Overview: We are seeking an experienced Medical Science Liaison (MSL) to join the TTR team and support Alnylam’s commitment to advancing the science and care of patients with transthyretin (TTR) amyloidosis. Patients often experience prolonged diagnostic journeys; this role is an opportunity to help elevate disease understanding and support evidence-based clinical decision-making through high-quality scientific exchange. The MSL will be principally responsible for building and sustaining scientific partnerships with key opinion leaders (KOLs), investigators, and other healthcare professionals within an assigned geography. The MSL will identify and address unmet medical education needs, deliver balanced scientific information (including mechanism of action and emerging clinical data), and gather actionable medical insights to inform internal stakeholders. Success in this role is grounded in Alnylam’s core values—our unwavering commitment to people, purposeful urgency, passion for excellence, fiercely innovative, and an open culture—while upholding the highest standards of integrity and compliance. This position partners closely with cross-functional colleagues (including Medical Affairs, Clinical Development, Market Access, and Patient Advocacy) to support strategic medical priorities for the TTR franchise and reports to the geographically aligned Field Medical Director. Key Responsibilities: - Partner closely with investigators and internal stakeholders to drive patient accrual. - Identify key opinion leaders and cultivate a network of experts for key Alnylam disease areas. - Develop, maintain, and execute US KOL and US Institution plans within respective geography. - Conduct and implement a comprehensive disease awareness tactical plan within the respective geography. - Collaborate with health care professionals to identify opportunities for the development of algorithms and guidelines to facilitate early diagnosis - Provide in-depth drug mechanism of action and emerging clinical information to health care providers in the respective geography. - Serve as a liaison to health care professionals and professional organizations and disease state advocacy groups. Support the efforts of patient support groups and educational foundations. - Provide medical and scientific input into the planning and execution of advisory boards and work with experts to review speaker presentations and provide additional medical background where requested. - Contribute to Alnylam's achievement of Company objectives for pre-approved products. - Provide educational meeting support at scientific congresses. - Coordinate required medical, legal, and regulatory review and approval of all field documents for distribution or presentation. - Require 60-70% travel. Qualifications: - PhD, PharmD, DNP or MD with 3 to 5 years’ industry experience. - Proven clinical background to enable engagement of Health Care Professionals in a scientifically meaningful exchange. - Prior experience in cardiology and rare disease strongly preferred. - Experience in clinical research, patient recruitment, and investigator-sponsored trials. - Experience in medical education and KOL management. - Effective communication of evidence based scientific information. - Ability to work collaboratively and cross-functionally. - Capable of managing shifting priorities in a rapidly changing environment - Decision-making and accountability. #LI-ST1 #LI-Remote U.S. Pay Range $187,700.00 - $253,900.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Overview: Reporting to the Site of Care National Director, the Strategic Account Lead, Site of Care will optimize access to Alnylam products through strategic engagement and contracting with key Alternate Site of Care accounts. This position requires a professional who can leverage their technical expertise and experience to facilitate access through innovation for patients and health care providers. A key component of this role is the ability to establish and deepen customer relationships through quality interactions at targeted strategic accounts. As such, extensive knowledge of ‘buy and bill’ products and prior experience with high-touch, specialty products is essential. The successful candidate must be passionate about science and deeply motivated by the quest of improving patient outcomes with the long-term success of the company in mind. They will work collaboratively with both internal and external stakeholders to execute strategic imperatives. Key Responsibilities: - Implement the comprehensive account strategy for key accounts to bring the best of Alnylam to the customer and to optimize access to Alnylam products. - Analyze and synthesize information from multiple sources to identify and prioritize business opportunities and potential risk across the accounts by applying relevant frameworks and analytical methods - Work with the National Strategic Account Director and provide insights that inform strategies, program objectives and KPIs for target accounts that are aligned with organizational and customer priorities - Anticipate and communicate likely or transpiring market and customer developments, identify third party factors and shape the account engagement strategy accordingly - Create and foster strong relationships and perception of Alnylam as a strategic partner with senior business stakeholders (C- and D-Suite) in target accounts and deliver on strategic goals for Alnylam’s products across the company portfolio - Ensure consistent, best-in-class site of care strategic account management practices across all customer engagements - Negotiate, manage and pull-through agreements that incorporate solutions to patient access and patient experience between Alnylam and strategic accounts - Collaborate with Commercial Leadership (Sales, Marketing, Market Access, Distribution and Operations) colleagues to ensure adequate Voice of the Customer in addition to own insights to influence strategic planning across stakeholders that encourages innovation and improves service delivery - Provide clear engagement direction to other field teams as they work with strategic accounts - Manage the ongoing contractual agreements and relationships with strategic accounts - Oversee the execution of quarterly business reviews, strategic planning sessions, and long-term roadmap development with key accounts Qualifications: - Bachelor’s degree required, emphasis in business management; Master’s degree preferred - Minimum 10 years’ of experience in the life sciences environment - Minimum 5 years’ previous account management experience with health systems or alternate sites of care C- and D-Suite or payors - High level of confidence, exceptional written and oral communication skills and executive presence required to engage with a C-Suite audience - Strong knowledge of the US payer landscape, value-based care and outcome-based models - Demonstrated ability to successfully mobilize cross-functional partners, including interpersonal skills to foster collaboration and succeed by leading without direct authority - Deep understanding of both medical benefit and pharmacy benefit - Strong analytical skills, able to synthesize multi-source information for strategic planning and ability to think critically, challenge conclusions and underlying assumptions - Self-starter who is enthusiastic about rare disease and Alnylam’s core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people - Highly proficient in Microsoft Office Suite - Ability to travel up to 75% - Should live near a mid-sized to major airport #LI-ST1 #LI-Remote U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

• Ensure adherence to standard operating procedures to maintain process consistency across the Ontario pharmacy network. • Ensure compliance with all regulatory and governing body requirements within the Ontario pharmacy network. • Advise business units, including Patient Support Programs and Provider Solutions, on regulatory compliance for pharmacy-related initiatives. • Facilitate effective collaboration and communication with stakeholders to sustain national pharmacy standards and processes in the Atlantic region. • Lead multidisciplinary teams at corporate, division, and facility levels to align quality and operational initiatives with organizational priorities. • Oversee the development and management of regional pharmacies, driving operational excellence. • Support regulated compounding activities, ensuring compliance with NAPRA standards. • Inform executive leadership about regulatory changes impacting pharmacy operations. • Manage relationships with pharmacy partners within the Atlantic region. • Monitor, and analyze performance metrics to meet established targets. • Align regional pharmacy objectives with corporate strategy, supporting the strategic planning process. • Oversee the regional pharmacy budget and capital investments. • Create and implement continuing education programs for pharmacy staff. • Collaborate with Pharmacy Managers to ensure budget adherence and identify cost-saving opportunities. • Oversee licensing and renewals for network pharmacies in the Atlantic region. • Represent pharmacy services at client quarterly business reviews, new business pitches, physician/clinic meetings, and internal discussions. • Inform and audit regional pricing strategies in Kroll. • Provide leadership and support to direct reports, including work allocation, hiring, training, and performance management. • Execute continuous improvement initiatives across regional pharmacies, sharing best practices across facilities. • Participate in audits and assist in implementing corrective actions as required. • Assist with other duties as assigned by the manager

• Establish the overall vision, mission, and strategic goals for PinnacleCare’s CIM program • Lead the development and implementation of a multi-year strategic plan to expand CIM services, identify innovative opportunities, and strengthen partnerships that enhance member value • Serve as PinnacleCare’s subject matter expert on complementary and integrative medicine, providing direct clinical consultation and guidance to health advisors and internal teams • Collaborate with the Chief Medical Officer (CMO) and organizational leadership to expand and manage the CIM Medical Advisory Board and provider referral network • Oversee program operations, productivity, and budget performance to ensure sustainability and measurable impact • Develop strategies to advance the visibility and increase usage of CIM services across the organization • Collaborate with the Research and Medical Intelligence teams in developing evidence-based reports, literature reviews, and data summaries on CIM topics • Work with the Director of Research to identify qualified members of the CIM clinical community to produce high level research reports for internal and external distribution • Maintain and enhance the CIM clinician and facility database to ensure it remains current, credible, and aligned with evidence-based practice standards • Participate in complex case reviews and facilitate referrals to qualified CIM clinicians and specialists within the network • Develop and deliver training and professional development programs on CIM approaches, modalities, and evidence-based practices for internal staff • Collaborate with Marketing and Communications to highlight CIM program value, outcomes, and innovations in internal and external publications • Represent the CIM program at internal meetings, external conferences, and industry events to build awareness and credibility • Support Membership Development and Relationship Management teams with CIM-related education, resources and client consultations • Provide operational oversight for all CIM activities to ensure high-quality member experience and alignment with PinnacleCare standards • Build and maintain relationships with CIM clinicians, vendors, and strategic partners to support service excellence and continuity of care • Identify and implement process improvements to enhance efficiency, member satisfaction, and cost effectiveness • Resolve clinical and operational issues related to CIM services and referrals in collaboration with internal and external partners