Genesis Molecular AI logo
Genesis Molecular AI

Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company’s generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets. Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.

Principal CADD Scientist

Research ScientistResearch ScientistFull TimeRemoteLeadTeam 51-200

Location

United States

Posted

72 days ago

Salary

0

Seniority

Lead

No structured requirement data.

Job Description

Principal CADD Scientist

Genesis Molecular AI

Genesis Molecular AI is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Principal CADD Scientist to join our team, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US. What You Will Do (Key Responsibilities) - Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents. - Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts. - Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches. - Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making. - Adapt to a fast-paced environment where innovation and quick iteration are encouraged. What you’ll bring - PhD in Computational Chemistry, Structural Biology, or a related field. This particular role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry with extensive experience in the lab, who have transitioned into industry roles in CADD. - Deep understanding of structure-based drug design and protein-ligand interactions. - Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite. - Minimum of 5+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs. - Onsite in our San Diego lab is preferred for this role, to be able to collaborate with our scientists. We are open to remote team members too. What we offer - Competitive Pay - Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees) - Stock Option Eligibility - 401(k) Plan - Open PTO Policy - Paid Company Holidays - Subsidized lunch and snacks at our offices About Genesis Molecular AI Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company’s generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets. Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.

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