Experienced CRA I - Sponsor Dedicated | Oncology + Neurology | 6 months of monitoring experience preferred (Home-Based - Dallas, TX) Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress. Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need. Discover what your 25,000 future colleagues already know: Why Syneos Health • We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program. • We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life. • We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress. Job Responsibilities - Performs site qualification, site initiation, interim monitoring, site management activities and close-out visits (performed on-site or remotely) ensuring regulatory, ICH-GCP and/or Good Pharmacoepidemiological Practices (GPP) and protocol compliance. Uses judgment and experience to evaluate overall performance of site and site staff and to provide recommendations regarding site-specific actions; immediately communicates/escalates serious issues to the project team and with guidance develops action plans. Maintains a working knowledge of ICH/GCP Guidelines or other applicable guidance, relevant regulations, and company SOPs/processes. - Verifies the process of obtaining informed consent has been adequately performed and documented for each subject/patient, as required/appropriate. Demonstrates diligence in protecting the confidentiality of each subject/patient. Assesses factors that might affect subject/patient’s safety and clinical data integrity at an investigator/physician site such as protocol deviation/violations and pharmacovigilance issues. - For the Clinical Monitoring/Site Management Plan (CMP/SMP): Assesses site processes Conducts Source Document Review of appropriate site source documents and medical records Verifies required clinical data entered in the case report form (CRF) is accurate and complete Applies query resolution techniques remotely and on site, and provides guidance to site staff as necessary, driving query resolution to closure within agreed timelines Utilizes available hardware and software to support the effective conduct of the clinical project data review and capture Verifies site compliance with electronic data capture requirements - May perform investigational product (IP) inventory, reconciliation and reviews storage and security. Verifies the IP has been dispensed and administered to subjects/patients according to the protocol. Verifies issues or risks associated with blinded or randomized information related to IP. Applies knowledge of GCP/local regulations and organizational procedures to ensure IP is appropriately (re)labelled, imported and released/returned. - Routinely reviews the Investigator Site File (ISF) for accuracy, timeliness and completeness. Reconciles contents of the ISF with the Trial Master File (TMF). Ensures the investigator/physician site is aware of the requirement of archiving essential documents in accordance with local guidelines and regulations - Documents activities via confirmation letters, follow-up letters, trip reports, communication logs, and other required project documents as per SOPs and Clinical Monitoring Plan/Site Management Plan. Supports subject/patient recruitment, retention and awareness strategies. Enters data into tracking systems as required to track all observations, ongoing status and assigned action items to resolution. - For assigned activities, understands project scope, budgets, and timelines; manages site-level activities / communication to ensure project objectives, deliverables and timelines are met. Must be able to quickly adapt, with the oversight of the Lead CRA, to changing priorities to achieve goals / targets. - May act as primary liaison with project site personnel, or in collaboration with another CRA or Central Monitoring Associate (CMA). Ensures all assigned sites and project-specific site team members are trained and compliant with applicable requirements. - Prepares for and attends Investigator Meetings and/or sponsor face to face meetings. Participates in global clinical monitoring/project staff meetings (inclusive of Sponsor representation, as applicable) and attends clinical training sessions according to the project specific requirements. - Provides guidance at the site and project level towards audit readiness standards and supports preparation for audit and required follow-up actions. - For Real World Late Phase, the CRA I will use the business card title of Site Management Associate I. Additional responsibilities include: Site support throughout the study lifecycle from site identification through close-out Knowledge of local requirements for real world late phase study designs Chart Abstraction activities and data collection Collaboration with Sponsor affiliates, medical science liaisons and local country staff Qualifications: - Bachelor’s degree or RN in a related field or equivalent combination of education, training and experience - Knowledge of Good Clinical Practice/ICH Guidelines and other applicable regulatory requirements - Must demonstrate good computer skills and be able to embrace new technologies - Excellent communication, presentation and interpersonal skills - Ability to manage required travel of up to 75% on a regular basis - US ONLY: As part of your employment with Syneos Health, you may be deployed to Sites that require certain medical and other personal information to gain facility access. Pursuant to our Employee Privacy Notice, Syneos Health can provide the Sites with the information necessary for you to gain such access. Further, a Site may ask you for additional information beyond that which Syneos Health has in its possession. You are required to comply with any such Site requests as a condition of your employment with Syneos Health. Please note that failure to provide requested information may result in a Site barring you from entry, which could put your ongoing employment at risk. At  Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements. Salary Range: The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role. Get to know Syneos Health Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients. No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health. http://www.syneoshealth.com Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

Purpose: The Clinical Research Lead helps drive the Foundation Fighting Blindness’ genetic testing program and My Retina Tracker® registry by coordinating with laboratory and scientific partners, managing data access requests, and contributing to strategic program evaluation while ensuring all work complies with contracts, standard operating procedures, and regulatory standards. Primary Responsibilities: The following are representative of the duties and responsibilities associated with this position and are not meant to be an all-inclusive list: - Serve as the primary point of contact for the sponsored genetic testing program, including management of relationships with laboratory partners and coordination of case identification activities - Use registry data to identify relevant cases that support sponsored genetic testing partnerships and fulfill data access requests from scientific collaborators. - Manage scientific partnerships, including contracting, data-sharing agreements, and ongoing relationship stewardship. - Build analytic datasets for scientific partnerships and data access requests, collaborating with internal team members who manage data infrastructure, cleaning, and import tools. - Contribute to the strategic evaluation of the genetic testing program, including analysis of program performance, partnership value, and potential alternative models to inform future funding and program decisions - Develop regular scientific publications and accessible research insights to be shared with registry participants and the broader community - Support the scientific activities of the My Retina Tracker® registry program, including annual review and update of data collection modules in collaboration with registry team members - Contribute to the development of policies and standard operating procedures, pertaining to data access, data privacy, and protection - Support annual priority and budget planning alongside the SVP and registry team. - Perform additional responsibilities as needed to support program success. Requirements: - Master of Science in Genetic Counseling (MSGC) or equivalent advanced degree in genetics, genomics, or a related life science field - Minimum 3 years of post-degree experience in a research, industry, or patient advocacy setting; experience with patient registries or sponsored genetic testing programs a plus - Demonstrated expertise working with genetic data, including variant-level analysis; familiarity with rare disease genetics and inherited retinal diseases preferred - Analytical mindset with an interest in program evaluation, strategic thinking, and evidence-based decision-making beyond day-to-day program operations - Strong interpersonal, verbal, and written communication skills; proven ability to work effectively with laboratory partners, scientific collaborators, and patient communities - Highly organized, detail-oriented, and able to manage multiple projects simultaneously in a fast-paced environment - Proactive, self-directed, and comfortable working independently in a remote setting - Proficiency with Microsoft Office; experience with research databases preferred Position Specifics: - Full-time (40 hours/week); Exempt; No Direct Reports - Work Environment: This is a work‑from‑home position, but not a “work from anywhere” role. Candidates must reside in the DC/MD region or the NC Triangle area to support collaboration and occasional in‑person activities. - Starting Salary: $112k-$125k annually. The range considers a wide range of factors that are considered in making compensation decisions, including but not limited to: geographic markets, skill sets, experience, and internal equity to comparable roles. - Monthly technology stipend provided - Annual incentive bonus eligible

Join Our Team as a Full-Time GWTG Clinical Data Abstractor (Exempt) at Carta Healthcare! Company: Carta Healthcare Inc. Position: Clinical Data Abstractor Location: 100% Remote (Exempt Position) Are you experienced in clinical data abstraction? Carta Healthcare Inc. is seeking talented individuals to join our growing team as Full-Time Clinical Data Abstractors! Join our team at Carta Healthcare, where we offer opportunities for experienced clinical data abstractors. We offer a flexible work schedule that allows for a balanced work-life experience. About Us: At Carta Healthcare, we are revolutionizing the way healthcare data is managed and used with innovative software solutions. Position Overview: As a Full-Time Clinical Data Abstractor, you will be responsible for abstracting and coding patient information from medical records to meet the requirements of various target registries. What We’re Looking For: - Minimum of 1 year of recent clinical data abstraction experience - Proficiency with EMR systems - Maintain a 98% or higher IRR score - Previous remote work experience preferred - Available for a minimum of 60 abstraction hours monthly Why Join Us? - Full-time, salaried exempt - 40 hours per week, Monday-Friday - $68,000.00 Annually - 100% remote - Laptop provided for Carta abstraction - Paid Holidays: 12 days per year - PTO: Carta Healthcare offers a flexible paid time off plan. Additional details will be shared during the hiring process. - Health Benefits: Medical, dental, and vision insurance. Includes extended PTO, bonus eligibility, and enhanced health plan tiers. - Overtime: No overtime eligibility (exempt classification) - Sick Leave: Per state/company policy In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire. All applicants are required to reside within the continental United States. Carta Healthcare is dedicated to building a diverse and inclusive company because we serve health systems across the country; we’ve seen how our product and impact are strengthened the more we reflect that diversity. In addition, we have found and strongly believe that diverse teams are higher-performing, and we embrace the varied perspectives that our team members share with each other. As such, we are an Equal Opportunity Employer. #LI-Remote #BI-Remote

Join Our Team as a Cath PCI Clinical Data Abstractor at Carta Healthcare! Company: Carta Healthcare Inc. Position: Full Time Cath PCI Clinical Data Abstractor Location: 100% Remote Are you experienced in clinical data abstraction? Carta Healthcare Inc. is seeking talented individuals to join our growing team as Full-Time Cath PCI Clinical Data Abstractors! Join our team at Carta Healthcare, where we offer opportunities for experienced clinical data abstractors. We offer a flexible work schedule that allows for a balanced work-life experience. About Us: At Carta Healthcare, we are revolutionizing the way healthcare data is managed and used with innovative software solutions. Position Overview: As a Full-Time Clinical Data Abstractor, you will be responsible for abstracting and coding patient information from medical records to meet the requirements of various target registries. What We’re Looking For: - Minimum of 1 year of recent clinical data abstraction experience - Proficiency with EMR systems - Maintain a 98% or higher IRR score - Previous remote work experience preferred - Available for a minimum of 60 abstraction hours monthly Why Join Us? - Schedule: 40 hours per week, Monday–Friday - Location: 100% remote - Equipment: Laptop provided - Paid Holidays: 12 days per year - PTO: PTO: Carta Healthcare offers a flexible paid time off plan. Additional details will be shared during the hiring process. - Health Benefits: Medical, dental, and vision insurance. Includes extended PTO, bonus eligibility, and enhanced health plan tiers. - Overtime: No overtime eligibility (exempt classification) - Sick Leave: Per state/company policy In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire. All applicants are required to reside within the continental United States. Carta Healthcare is dedicated to building a diverse and inclusive company because we serve health systems across the country; we’ve seen how our product and impact are strengthened the more we reflect that diversity. In addition, we have found and strongly believe that diverse teams are higher-performing, and we embrace the varied perspectives that our team members share with each other. As such, we are an Equal Opportunity Employer. #LI-Remote #BI-Remote