Role Description This role is a project-based consulting opportunity to conduct medical monitoring on an as-needed basis. This is not a full-time position. - Provide medical input into the development and execution of study documents and plans, such as study protocol, IB, SMP, DMP, SAP, Lab manuals, etc. - Provide medical expertise to sponsors in the drug development process. - Provide significant expertise as primary medical reviewer of individual adverse event reports, clinical, and safety documents. - Lead safety activities on assigned product(s) that may include interactions with other functional groups in the company. - Responsible for medical monitoring tasks, which may include: - Eligibility review - Review of safety-related protocol‑related deviations - Review of safety data - Develop Medical Monitor Plan - Participation in medical monitoring and/or safety review meetings as needed - Medical management of queries - Medical coding review - Maintain records and logs - Medical review of study documents - Responsible for strategies in pre and post marketing risk management, as well as keeping abreast of pharmacovigilance methods and trends in published literature and global regulations. - Responsible for strategies in monitoring and analysis of cumulative safety information. - Maintains significant knowledge of global and local regulations and guidance as they pertain to medical review and safety reporting. Qualifications - Medical degree required (MD or equivalent) - Specialty in Ophthalmology or comparable experience in Ophthalmology - 5 or more years of clinical experience and/or research experience required - Relevant experience in safety physician, safety committee membership, medical monitoring and/or medical reviewer in pharmaceutical industry - Excellent scientific writing skills - Ability to understand clinical data - Proficiency with MS Office applications - Good communication skills - Strong knowledge of current regulatory practices and domestic and international regulations

Role Description The Case Manager is a professional external-facing role, responsible for oversight of cases throughout the authorization/approval journey for patients and their providers. This role relies on critical thinking skills to drive cases through complex authorization and appeal processes, focusing on expediting patients’ access to care while securing payment channels to avoid unexpected out-of-pocket costs. This may involve interacting with private commercial or government-run insurers, healthcare providers, suppliers/distributors, and patients to ensure access across the care continuum. Must be available to work normal business hours (8A-5P) in either Central or Eastern Time Zones. Core Duties/Responsibilities: - Act as a single point of contact between the internal team, client, provider, payor, facility, and patient as needed. - Support cases through approval/denial process with a sense of urgency while maintaining accuracy. - Provide direction to the aligned Payor Specialist Team and coordinate efforts to ensure accuracy and completeness of each case. - Identify and share trends impacting business processes with management. - Prioritize and act on key client activities and follow up with customers to ensure problems are solved. - Manage through ambiguity while designing innovative client and payor solutions. - Make sound independent decisions in urgent and non-routine situations pertaining to client and patient scenarios. - Interpret complex clinical documentation to prepare authorization documentation for payor submission in relation to medical policy criteria for coverage. - Partner with the interdisciplinary team to champion their clients, patients, and customers and is responsible for the life cycle of their case to ensure successful completion. - Provide resources to patients, caregivers, health care providers, and clients with resources available for financial assistance and transportation. - Provide compassionate and empathetic support to patients and caregivers with life-threatening diagnoses. - Coordinate with various service providers and healthcare professionals to ensure patients receive the appropriate support before and after surgery. Qualifications - Maintains open, effective dialogue with effective communication and is both clear and thorough in reports, documentation, and other written communications. - High level of ability to coordinate multiple priorities and activities to accomplish goals. - Ability to independently manage case load, prioritize work, and use time management skills to manage deliverables. - Critical thinking and strong problem solving. - Suggests creative ideas and innovative solutions while exploring multiple alternatives and approaches to overcome obstacles and find solutions. - Excellent follow-through with solid levels of determination and tenacity. - Remains calm and productive during transitions or changing circumstances. - Demonstrates composure and professionalism under difficult circumstances. - Ability to communicate effectively both orally and in writing with a focus on customer satisfaction, with empathy, drive, and commitment to exceptional service. - Possess a strong understanding of the US Healthcare System, public and private payer nuances, and patient access challenges for new to market, high dollar or highly complex medical interventions, products, therapies. - Ability to leverage professional expertise and apply company policies and procedures to resolve challenges. - Ability to develop, maintain and navigate relationships. - Ability to interpret and understand medical documentation as it relates to each specific case and how it applies to a specific medical policy. - Ability to be agile and adaptable in responses to rapidly changing processes and consumer needs. Requirements - College Degree preferred (bachelor’s or associate degree). - 4 – 6 years of experience in a healthcare setting and/or medical insurance background with a customer service focus. - Nutrition background with Case Management experience strongly preferred. - Experience as Clinical Dietitian a plus. - Experience with prior authorizations and appeals submissions desired. - Knowledge of reimbursement processes a plus. - Experience with maintaining detailed records of client interactions, services provided, and progress made. - Experience in developing and/or implementing new technologies a plus. - Experience with complex medical products and associated insurance processes a plus. Physical Requirements - As a remote-forward organization, this position operates in a professional office environment and teleworking from the employee’s home address listed in their employment file. - Prolonged periods of sitting at a desk and working on a computer. - Keyboarding. - Speaking. - Must be able to lift up to 15 pounds at times. - Flexibility of working hours to support activities across CST to EST zones. Benefits - Robust medical, dental, and vision plans. - Life insurance and disability coverage. - Tax-advantaged savings accounts. - Employee Assistance Program. - Home office benefits. - Employee Ownership Program. - Paid time off, holidays, and bereavement leave. - 401(k)-retirement plan with employer matching. - Performance-based bonus opportunity.

Who We Are: Cogent Biosciences is a publicly traded biotechnology company focused on developing novel precision therapies to treat a broad range of patients with unmet medical needs. Cogent’s lead program, bezuclastinib, is designed to selectively and potently inhibit exon 17 mutations found within the KIT receptor tyrosine kinase, including KIT D816V. KIT D816V is responsible for driving a rare and serious condition called Systemic Mastocytosis, and exon 17 mutations are also found in patients with gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. Bezuclastinib has exhibited promising initial data across all three trials: APEX in AdvSM, SUMMIT in NonAdvSM and PEAK in GIST, including an encouraging safety profile across 600+ patients in single agent and combination dosing. The Role: The Senior Medical Science Liaison (MSL) will serve as a senior field-based scientific expert supporting Cogent Biosciences’ lead program, bezuclastinib. This role focuses on scientific engagement across oncology (solid tumors/sarcoma, including Gastrointestinal Stromal Tumor [GIST]), hematology/oncology (Non-Advanced and Advanced Systemic Mastocytosis), and allergy/immunology (Non-Advanced Systemic Mastocytosis) within the assigned territory. The Senior MSL will collaborate with cross-functional partners to develop strategic, scientifically aligned regional business plans that support corporate objectives. The Senior MSL will mentor colleagues, work closely with Field Medical Affairs Area Directors and Medical Strategy, and ensure consistency in scientific communication nationally. This role will also contribute to ongoing education for Medical Affairs, Patient Advocacy, and Commercial teams. Maintaining alignment in field scientific discourse is essential to ensuring accurate communication of key data and scientific messages. The Senior MSL serves as a leader on the designated regional team and plays a critical role in fostering unified communication and collaboration across all external-facing functions, including commercial and patient advocacy. The Senior MSL will also promote and support consistency across the MSL team, share best practices, and guide prioritization of insights and administrative deliverables. The Senior MSL is Field Leader/Strategic Advisor that requires high emotional intelligence and the ability to influence without authority. The Senior MSL ensures that field strategies and tactics are supported by robust, fair-balanced scientific data. The successful candidate thrives in a fast-paced environment and is motivated by improving the lives of patients with unmet medical needs. This is an exceptional opportunity to join Cogent during a transformative period as the organization leads scientific exchange, engages with KOLs and HCPs, and advances our clearly differentiated, next-generation therapy for patients affected across the spectrum of NonAdvanced and Advanced SM and the potential for a paradigm shift of a new standard of care for second-line treatment of imatinib resistant or intolerant GIST patients. Responsibilities: - Manage the assigned territory as a scientific and medical expert in GIST and Systemic Mastocytosis. - Help shape marketing strategy by translating complex scientific data into actionable clinical insights, identifying unmet needs through KOL engagement, and mapping the therapeutic landscape to guide product positioning. - Support strategic priorities developed in collaboration with Medical Affairs and Patient Advocacy, aligned with corporate goals and ongoing clinical development and commercialization activities. - Develop and execute a territory strategy aligned with regional business objectives while ensuring compliant, accurate, data-driven scientific exchange. - Lead scientific engagement with thought leaders, subject matter experts, investigators, and HCPs to gather insights on clinical practice, scientific developments, and competitive trends. Cultivate peer-to-peer relationships with top-tier scientific and medical experts (KOLs). - Build and maintain a strong network of experts; implement thought-leader development plans; increase awareness of Cogent, bezuclastinib, and the pipeline. - Facilitate investigator-initiated research and real-world evidence proposals aligned with the Lifecycle Management Team. - Support the Market Access team in delivering educational programs and resources on an as needed basis. - Support Clinical Development to identify clinical trial sites as needed. - Collaborate with Research and Scientific Affairs to identify and engage KOLs with interest in pipeline programs as needed. - Demonstrate proactive, innovative thinking to support regional and corporate objectives. - Maintain required training and adhere to all compliance standards for scientific interactions and safety reporting. - Develop and implement educational outreach strategies including advisory boards, lunch-and-learns, roundtables, grand rounds, and encore presentations. - Support scientific congresses through booth staffing, session coverage, competitive intelligence gathering, and meeting coordination. - Monitor competitive activities and trends; communicate insights across U.S. and global teams. - Lead onboarding and ongoing training for new Medical Affairs, Commercial, and cross-functional colleagues. - Foster a collaborative, innovative culture. - Complete administrative tasks accurately and on time; ensure consistent CRM documentation and insights reporting. - Travel up to approximately 80% within the assigned territory. Qualifications: - Advanced medical or scientific degree required (Master’s or Doctorate). - Medical professional credentials preferred (MD, DO, PhD, DNP, PharmD, etc.). - 7+ years of biotech or pharmaceutical Medical Affairs experience, including commercial launch experience. - 3+ years of hematology/oncology experience required; mastocytosis or MPN/MDS, and/or allergy/immunology experience preferred. - Has demonstrated success in supporting product launch(es) - Established relationships with KOLs and HCPs in SM and/or GIST preferred. - Demonstrated success collaborating with multidisciplinary teams in small- to mid-size biopharma. - Experience engaging relevant Market Access scientific teams preferred. - Strong understanding of healthcare compliance and regulatory standards. - Excellent analytical skills and ability to interpret scientific literature and clinical data. - Strong communication, presentation, and interpersonal skills. - Creative problem-solving ability and a solutions-oriented mindset. - Highly adaptable, energetic, and comfortable in a fast-paced environment. Salary Range: $205,000 - 240,000 USD Target Bonus: 20% Exact compensation will vary based on skills, experience, and location. Our Locations Waltham, MA: Our headquarters is located in the Greater Boston life sciences community, with an open, collaborative office environment designed to support teamwork and connection. Employees benefit from convenient on-site amenities, including free on-site parking and gym facilities in the building. Boulder, CO: Our Boulder location is home to Cogent’s discovery research organization and a key scientific hub with strong leadership based on site. Situated in the greater Denver-Boulder biopharmaceutical corridor, this office plays a central role in advancing our discovery efforts and pipeline. Our Offer To You At Cogent Biosciences, we offer a competitive salary, bonus, and ongoing stock awards, alongside a benefits package that sets us apart. We cover 100% of medical, dental, and vision premiums for you and your family, and help reduce out-of-pocket costs by funding up to 75% of in-network deductibles. Our benefits also include a 401(k) match with immediate vesting, generous paid time off, 12 weeks of fully paid parental leave, paid family and medical leave for all employees regardless of location, and company-paid short-term disability coverage for up to 20 weeks. Additional perks like wellness programs, tuition reimbursement, and inclusive family-forming support help you thrive at work and beyond. We are proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability, or any other status protected under federal, state, or local law. All employment is decided on the basis of qualifications, merit, and business need.

Overview Perinatal Revewer can work anywhere in the United States. - Perinatal Reviewer, with minimal immediate direction or supervision, survey and/or review health care organizations throughout the United States. - Perinatal Reviewer apply sophisticated analysis skills and inductive reasoning skills to determine a health care organization's degree of compliance with applicable standards and functionality of care delivery systems. - Perinatal RN Reviewer must have the credentials, presence and expertise to earn the respect of the health care organizations' professional staff and leadership. - Perinatal RN Reviewer must be able to employ advanced and sometimes nuanced communication skills to engage health care organization staff in interactive dialogues on a broad array of health care issues in order to assess compliance and to identify opportunities for improving compliance. - Perinatal RN Reviewer must have superior written communication skills to prepare detailed, accurate management reports that clearly link individual standards deficiencies with potential systems vulnerabilities and related organization risk points. - Perinatal RN Reviewer must be able to professionally and effectively communicate survey results to health care organization leadership in a constructive and collegial style. - Perinatal RN Reviewer are also required to participate in other Joint Commission activities as assigned. Qualifications - DSC Perinatal Reviewers must be a healthcare professional (DO/ MD/RN) with at least three years’ experience in coordinating and/or managing the services of Delivery, Postpartum Care, Special Care Nursery, as well as Pediatrics with in an acute care setting. Must have direct experience with at least 2 Joint Commission certifications reviews. - Must have current experience in Labor & Delivery, Maternal Care or Neonatal Care. - The following certifications are preferred: NeoNatal-Perinatal medicine and/or RN-Board Certified in Perinatal Nursing and/or Perinatal Care Certification through Joint Commission. - Registered Nurses requires a Master’s Degree This position is a .23 FTE. ( One week per month and could include Sunday travel) All positions require 100% nationwide travel. We are currently hiring for our next orientation class to take place on May 5, 2026 or June 8, 2026 Min USD $115,000.00/year Max USD $115,000.00/year