Rhythm Pharmaceuticals

Lead global payroll operations, ensuring compliance and accuracy across multiple regions. Manage payroll teams, oversee wage payments, and collaborate with finance and HR to enhance payroll processes and resolve employee inquiries.

Title: Director, Value and Evidence Location: Boston, MA Department: Medical Affairs Job Description: Company Overview Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together. Opportunity Overview Rhythm seeks an experienced individual to join our Medical Affairs North America team as Director, Value & Evidence. This position will serve as a strategic bridge between clinical development, regulatory and commercial roles, responsible for generating high quality evidence to maximize the value proposition of our assets across multiple indications associated with rare neuroendocrine diseases. This role requires leading the design and execution of studies with a focus on Patient Reported Outcomes (PRO)/Clinical Outcomes Assessments (COA), real world evidence generation and health economics and value dissemination. This individual will collaborate across regional teams, delivering evidence and/or tools to optimize decision making, support access and reimbursement and inform medical and clinical research protocols. This position will report to the Head of Value & Evidence (V&E). Responsibilities and Duties - Demonstrate proven methodological and analytical expertise regarding the collection, analysis, and utilization of real-world data to provide high-quality project deliverables including abstracts, posters, and manuscripts. - Demonstrate proven expertise leading Health Economic and Outcomes Research (HEOR)/real world research in the forms of COA development and/or its validation, database analysis, observational research, PRO endpoint inclusion in product labeling and other types of HEOR research. - Proactively propose and prepare outcomes research protocols, statistical analysis plans (SAPs), and reports. - Drive longitudinal retrospective studies of existing databases to assess patient characteristics, treatment patterns, and associated clinical, economic and/or patient-reported outcomes. - Lead retrospective or prospective evaluations of disease natural history and treatment patterns, including drug utilization and adherence. - Drive cross-sectional surveys of patients, caregivers, health care providers/practitioners, and/or payers/health technology assessment authorities. - Lead clinical-economic models and assessments exploring burden of illness and/or comparative effectiveness. - Ensure findings are communicated effectively, and as appropriate in conference presentations, publications, dossiers and other means. - Create robust health technology assessment (HTA) tools to meet the evidentiary standards of regulators, HTA organizations, reimbursement authorities, third-party payers and other organizations that review evidence for formulary and access decision making. - Ensure and drive strategic alignment with internal teams including Medical Affairs, Market Access, Regulatory, Commercial, International and Clinical Development to incorporate strategic HEOR and COA needs at every stage of development program and throughout commercial availability. Qualifications and Skills - 10+ years of relevant education and experience, including time in the bio-pharmaceuticals industry, with majority of experience in PRO drug development, regulatory submissions and the commercialization process, including designing health economics and outcomes research and evidence generation independently/autonomously. - Advanced degree in epidemiology, health economics, pharmaceutical sciences, or related discipline (MS, MPH, PharmD, PhD) preferred. - Experience in rare diseases strongly preferred. - Knowledge of the drug development & commercialization process, HTA assessment methodologies, global reimbursement, US payers and regulatory requirements. - Experience in developing submissions to European-based HTA organizations. - Excellent communication, collaboration and influencing skills across internal and external stakeholders. - Well-organized with strong project management skills and ability to prioritize workload This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve some travel. The expected salary range for this position is $182,000 - $275,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units. More about Rhythm We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism. At Rhythm our core values are: - We are committed to advancing scientific understanding to improve patients’ lives - We are inspired to tackle tough challenges and have the courage to ask bold questions - We are eager to learn and adapt - We believe collaboration and ownership are foundational for our success - We value the unique contribution each individual brings to furthering our mission Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law.

Company Overview Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to learn, adapt and our tenacity to overcome barriers, together. Opportunity Overview The (Senior) Brand Manager, Germany, Switzerland, Austria (GSA) is responsible for (co)-leading the development, localization, and execution of marketing initiatives across Germany, Switzerland, and Austria. Reporting to the Marketing Director GSA, and working closely with International Marketing, Medical Affairs, Sales, other cross‑functional stakeholders, and the Swiss and Austrian Country Operations Leads, the role ensures strong brand integration, compliant execution, and measurable business impact across the GSA region. Responsibilities & Duties Strategy & Planning - Support the execution of international strategic and tactical marketing plans, ensuring effective localization and implementation across the GSA region. - Act as the regional marketing responsible person, alongside the Marketing Director for GSA, ensuring alignment with international brand strategy and regional business priorities. - Lead the development and implementation of local tactics and programs. Marketing Execution & Omnichannel Excellence - Drive the development and execution of integrated marketing initiatives across the full product lifecycle, in close collaboration with Medical Affairs, Sales, and other cross‑functional teams. - Oversee the creation and implementation of local high‑impact promotional programs, with a strong focus on digital innovation, omnichannel engagement, and patient‑centric initiatives. - Act as marketing specialist and brand integrator for regional initiatives, proactively identifying opportunities and addressing local market challenges. - Responsible from the handoff from marketing to the sales team, ensuring an aligned strategic and tactical execution with the support needed to deliver impact in HCP interactions. Compliance & Stakeholder Management - Guide marketing tactics through internal approval processes, ensuring full compliance with Legal, Medical, and Regulatory (LMR) requirements. - Build and maintain strong relationships with key internal and external stakeholders, including agencies and partners, to ensure high‑quality execution. Events & Congresses - Lead the planning and execution of congresses and events relevant to the GSA markets. Performance, Budget & Analytics - Establish and monitor key performance indicators (KPIs), analyze trends, and optimize marketing tactics using a data‑driven approach. - Effectively manage and optimize the regional marketing budget across all projects within scope. - Generate actionable insights from performance data (e.g., omnichannel engagement, campaign results, sales), translating findings into clear recommendations to refine strategy, optimize tactics, and improve customer experience. Qualifications & Experience Education - Bachelor’s degree in science, pharmacy, or medical science; Master’s degree in Marketing and/or Business Administration are an advantage. Professional Experience - Minimum of 5 years’ experience in national pharmaceutical marketing (within GSA region); experience in Sales is a key requirement - Experience in rare diseases and pharmaceutical product launches is highly desirable. - Proven track record of commercial success through strong execution in complex, cross‑functional environments. - Prior experience in a start up or fast growing small to mid-size company preferred Qualifications & Skills - Strong experience in omnichannel campaign development targeting HCPs and/or patients, including CRM, opt‑in programs, and digital formats such as webinars. - Excellent project management skills with the ability to manage multiple initiatives in parallel while maintaining a high level of execution and on time delivery. - Strategic, out‑of‑the‑box thinker with a strong interest in innovative marketing approaches. - Strong leadership skills with the ability to influence without direct authority in a fast‑moving environment. - Self‑starter with a hands‑on mindset who takes ownership and drives execution. - Excellent written and verbal communication skills in English and German; Italian and French is an advantage, yet no requirement. - Proficient in Microsoft Office (PowerPoint, Word, Excel) and familiar with AI tools. This role will be based within the GSA region (with an affiliate office in Central-Munich) in a remote setting. Although remotely, candidates applying must be willing and able to meet for collaborative purposes (e.g. workshops, strategic and tactical planning) & congresses (regional, national, international) and have easy access to transportation and airports. More about Rhythm We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel