Exact Sciences

• Lead in the execution of the strategic direction for ML, NLP, LLM, and algorithm development within a world-class AI ML team, working closely with well-renowned experts in AI/ML modeling, ML engineering, data science, and data engineering • Partner with AI leadership to identify opportunities to leverage AI technologies to improve efficiency, productivity, and innovation • Collaborate closely with business stakeholders, data scientists, machine learning engineers, and software engineers to ensure smooth integration of machine learning models into production systems • Partner on the execution of custom ML, Gen AI, NLP, LLM Models for batch and stream processing-based AI ML pipelines including data ingestion, preprocessing modules, search and retrieval, Retrieval Augmented Generation (RAG), NLP/LLM model development and ensure the end-to-end solution meets all technical and business requirements, and SLA specifications • Complete the development and deployment of AI models and algorithms to solve complex problems • Ensure the robustness, scalability, and performance of AI systems and solutions • Stay updated on advancements in AI research and technology to guide initiatives • Foster a culture of innovation, collaboration, and continuous learning within the team • Coach, support, and provide mentorship for team members • Ensure stakeholder needs are met through effective communication and collaboration • Promote understanding of AI capabilities and limitations across the organization • Champion ethical AI practices and ensure compliance with regulatory standards • Address issues related to data privacy, security, and biases in AI systems • Develop policies that promote transparency and accountability in AI applications.

• Collaborate with CDX Strategists, CDX Researchers, the Experience Management & Capability team and the respective Experience Design team members to produce Service Design deliverables (e.g., Service Blueprints) for one or more Journeys in a given Experience that are integrated, cross-touchpoint, cross-Customer Type, and Cross-Experience/Journey. • Assist with the design, execution, and incorporation of user research into the design of the relative Journeys. • Facilitate the use of Design Thinking, storytelling, and conceptual prototypes to compellingly convey the vision, flow, and features of the products/services being designed. • Facilitate creation and adoption of design systems, website interaction models, information architectures, user task flows, and screen designs; turn complex information into intuitive graphics, charts, and other forms of visualization data. • Facilitate use of ideation and sketching for storyboards and prototyping; create low- and medium-fidelity prototypes to test proposed Journeys. • Support the adaption of the enterprise wide UX best practices, standards, principles, and design thinking processes for use by the respective UX, Product, and Engineering teams; advocate for these standards, principles, processes. • Support collaboration with Strategy, Product, and Engineering peer leadership to foster active collaboration across the teams, remove impediments, and ensure delivery of the overall Experience vision & OKRs. • Support advocacy for the Experience's/Journey’s UX vision. • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork. • Support and comply with the company's Quality Management System policies and procedures.

• Responsible for the accurate and timely work of filing insurance claims for Exact Sciences • Demonstrate medical insurance knowledge by determining initial and/or ongoing eligibility, coverage, and related insurance reimbursement order details • Identify order and reimbursement deficiencies and route orders for appropriate actions • Support broader activities ensuring appropriate coverage by utilizing Epic, external portals, and other software • Monitor WQ’s for claims needing additional research and actions taken to get on the path of resolution • Follow up with payors on unpaid aging claims • Complete position responsibilities within the appropriate time frame while adhering to quality standards

• responsible for the accurate and timely work of filing insurance claims for Exact Sciences • demonstrate medical insurance knowledge by determining initial and/or ongoing eligibility, coverage, and related insurance reimbursement order details • identify order and reimbursement deficiencies, route orders for appropriate actioning, and document actions taken within the systems for claims lifecycle tracking • support the broader activities of ensuring appropriate coverage by utilizing Epic, external portals, and other software • communicate insurance information to ancillary departments and other teams within the reimbursement operations departments

• Design clinical validity, clinical utility, health economics, and clinical experience studies. • Evaluate evidentiary requirements. • Contribute to proposals, FDA pre-submissions, and study protocols (selecting endpoints, power and sample size calculations, and analysis plans). • Review case report forms and data transfer requirements. • Author statistical analysis plans. • Apply rigorous statistical methodology and programming to monitor clinical data quality. • Develop evidence for clinical predictive models in clinical studies and trials. • Conduct simulation studies. • Communicate statistical results in tables, figures, and listings; statistical analysis reports; clinical study reports; abstracts; manuscripts; regulatory submissions; presentations; and marketing collateral. • Evaluate investigator sponsored study designs and analysis plans, evidence developed for external molecular tests, and applicability of novel statistical techniques.

• Collaborates with interdisciplinary, cross-functional teams to develop and establish evidence for molecular tests for screening, diagnosis, prognosis, monitoring, and therapy selection in oncology • Assist the biostatistical function on project-level work • Provide input into the design of analytical validity, clinical validity, clinical utility, health economics, and clinical experience studies • Evaluate evidentiary requirements • Contribute to proposals, FDA pre-submissions, and study protocols • Review case report forms and data transfer requirements • Draft statistical analysis plans • Monitor laboratory and clinical data quality • Develop evidence for clinical predictive models in clinical studies and trials • Conduct simulation studies • Communicate statistical results in various formats • Evaluate investigator-sponsored study designs and analysis plans

Role Description This position may be site-based or remote in Chicago, Boston, San Diego, or Minneapolis. Exact Science’s Customer Experience (CX) team is responsible for defining, driving, and delivering innovative, immersive, memorable customer-centric journeys for all our customers, across all channels. These journeys are grouped by Customer Types (e.g., Patient, Provider) and further categorized into a set of Experiences (e.g., Understand Risks & Complete Screening, Confirm Diagnosis). Each Experience has a set of specific, measurable Objectives and Key Results (OKRs) that the overall team is accountable to fulfill. As a Lead Designer, Marketing Communications, you will help shape, define, and drive high-impact design initiatives across digital, product, and marketing platforms. You will blend systems thinking with hands-on execution, bringing structure to complex problems and elevating the craft of design through thoughtful, scalable, human-centered solutions. You’ll lead by example, guiding teams toward clarity, consistency, and innovation. You will guide experience vision, interaction patterns, and system-level design across journeys and touchpoints, helping to unify design efforts across web, mobile, physical, and hybrid platforms. Your design work is grounded in deep empathy, curiosity, and a strong understanding of user mindsets, behaviors, and expectations. You design with people at the center, delivering solutions that reduce friction, build trust, and empower patients and providers to make confident, informed decisions. You excel at balancing the strategic and the tactical, able to see the big picture of experience ecosystems while refining the details of interaction design, flows, and component-level polish. You bring structure to ambiguity, elevate the role of design in cross-functional work, and advocate for excellence at every level of execution. Your approach is rooted in systems thinking, iterative testing, and collaborative problem-solving, always with an eye toward both business outcomes and human impact. As a hands-on, proactive, collaborative design leader, you’ll work closely with Product Managers, Engineers, Researchers, Content Strategists, and Legal, Marketing, and Medical partners. You’ll help teams navigate complexity, compliance, and competing priorities, driving forward experience strategies that are scalable, accessible, and compliant. You’ll shape the end-to-end design process and help teams deliver solutions that balance innovation with feasibility. As a craft leader and mentor, you’ll model design excellence and help build a culture of feedback, continuous learning, and shared ownership. You’ll support junior and mid-level designers in growing their skills and craft while contributing directly to high-impact work. You know how to guide vision, define process, manage stakeholders, and roll up your sleeves to contribute at every level, ensuring quality delivery. You have a strong track record of delivering thoughtful, inclusive, and high-quality digital experiences in complex environments. You’re able to balance priorities and understand the impact of key decisions. Your leadership empowers cross-functional teams to execute design that’s not only effective but deeply human. You should be prepared to share a portfolio that demonstrates your ability to simplify complexity, bring strategy to life through experience, and create work that resonates with diverse audiences. Your work reflects a deep commitment to solving the right problems, driving meaningful outcomes at scale, and facilitating thoughtful interactions. Essential Duties - Independently lead and facilitate active collaboration with strategists, researchers, product leaders, legal, regulatory, medical, labs, and the respective Experience Design team members to produce deliverables that scale across journeys and platforms, with minimal guidance. - Support a team of designers, providing informal coaching, feedback, and direction to help them do their best work on a project. - Research and stay up-to-date to help support the adoption of the enterprise-wide design best-practices, standards, principles, and the usage of AI into your daily practice. - Develop advanced prototypes and animations or define motion characteristics. - Advocate for the incorporation of user research into the experience's UX vision, provide strategic rigor and thoughtfulness throughout the creation of products and experiences, from vision and conception to launch and optimization/governance. - Evolve and champion our design system to ensure that it is driving efficiencies and is tailored to the respective audience needs. - Serve as a subject-matter expert in all things design and help lead both partners and peers alike to help think how design drives utility and inspires, equally. - Remove impediments and ensure delivery of the overall experience vision & results aligned to OKRs. - Building and maintaining collaborative relationships with senior leadership and other departments (e.g., Marketing) will also be required. - Create systems and strategies that help designers thrive. - Lead the use of design thinking, storytelling, and conceptual prototypes to compellingly convey the vision, flow, and features of the products/services being designed. - Understand and prioritize time, problems, opportunities, and solutions that contribute to the product roadmap, strategy, and vision leveraging data, research, industry trends, and business objectives. - Maintain morale and support employee engagement initiatives. - Foster a welcoming environment regardless of background, sexual orientation, gender expression, religion, or ethnicity, and model these behaviors for the organization. - Work within established design systems to create bold and memorable experiences that are consistent across multiple channels including web and email marketing or other customer interaction points. - Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork. - Ability to effectively manage legal reviews and feedback cycles. - Support and comply with the company's Quality Management System policies and procedures. - Ability to act with an inclusion mindset and model these behaviors for the organization. - Travel Requirements: Ability to travel 10-20% of working time away from work location, may include overnight/weekend travel. Qualifications - Bachelor’s degree in Design, Marketing, Business, Life Sciences, or related field of study; or High School Degree/General Education Diploma and 4+ years of relevant experience as outlined in the essential duties in lieu of Bachelor’s degree. - 8+ years of experience working as a UX Designer, with at least 5 years of experience in a senior or lead capacity. - Extensive experience in applying techniques and methods of modern user experience design, discovery, and delivery – along with expertise with design/user experience platforms and tools (e.g., Adobe Creative Suite, Figma, Miro, Jira). - Experience with content management systems (Sitecore a plus) and user testing tools. - Experience in simplifying and communicating complex ideas to broad audiences. - Experience in managing a design process from strategy to delivery of final product. - Experience in collaborating with and influencing product, engineering, design, and operational teams. - Experience in creating designs that optimize for varied ecosystems that leverage known persona or archetypal work, SEO, and measurement objectives. - Advanced understanding of accessible, inclusive, and equitable design. - Experience with the principles of Agile/Scrum/Kanban. - Strong organizational and time management skills with a proactive and logical approach to workload and ability to work both independently and within a team. - Demonstrated ability to perform the Essential Duties of the position with or without accommodation. - Strong working knowledge of HTML, CSS, JavaScript, Adobe Creative Suite applications, and associated design tools. - Demonstrated strong understanding of the current web and mobile technology landscape. - Advanced understanding of human centered design and design thinking methodologies. - Experience creating accessible, inclusive, and equitable design. - Knowledge of best-in-class design systems (Material, Carbon, Fluent, etc) and their pros and cons. - Experience in evolving/adapting design systems or building them from scratch. - Extensive experience problem-solving, organizational, and analytical skills with the ability to evolve UX strategy based on research, data, and industry trends. - Strong analysis skills; including, but not limited to, process and user flow definition. - Extensive experience in translating complex user, business, operational, and technical requirements into clear, accurate, compelling user experience deliverables. - Experience in relationship building, motivation, and curiosity to bring together different personalities for creative thinking and collaborative solutioning. - Extensive experience engaging with strategists, product managers, engineers, researchers, SMEs, and company leaders in a constructive and collaborative relationship where you can both learn and influence. - Experience recruiting, coordinating, developing, and managing a team. - Excellent written and verbal communication skills, with the ability to agilely adapt to the respective audience (team member to senior leadership). - Strong organizational and time management skills with a proactive and logical approach to workload and ability to work both independently and within a team. - Demonstrated ability to perform the Essential Duties of the position with or without accommodation. - Applicants must be currently authorized to work in the country where work will be performed on a full or part-time basis. We are unable to sponsor or take over sponsorship of employment visas at this time. Preferred Qualifications - Experience in healthcare, wellness, or digital health. - Experience with service design and operations. - Experience with both B2C and B2B products and/or services. - Experience within large organizations. - Experience with Sitecore, React, and Angular frameworks. - Experience with no-code tools to help support the experience. - Experience using AI to help enhance experiences or create efficiencies in process. Benefits - Paid time off (including days for vacation, holidays, volunteering, and personal time). - Paid leave for parents and caregivers. - Retirement savings plan. - Wellness support. - Health benefits including medical, prescription drug, dental, and vision coverage. Salary Range - $124,000 - $211,000.00 (National Salary) - $150,420.00 - $225,630.00 (California Salary)

Role Description The Sr. Principal Medical Development Director, Breast Portfolio, will be responsible for clinical and translational leadership in the development and execution of the company’s precision oncology strategies; including, but not limited to, the design and implementation of next-generation sequencing (NGS) based assays. - Develop, validate, and gain regulatory approval for diagnostic tests for breast cancer patients. - Provide medical leadership during the design, implementation, and reporting of studies supporting pipeline products and line extensions. - Develop external relationships with oncology leaders and identify investigators for clinical trials. - Initiate and lead external ad boards involving medical leaders and key opinion leaders. - Review, interpret, and lead the translation of key study results into evidence-based claims. - Design and implement medical support for new or extended precision oncology tests and services. - Participate on internal cross-functional program teams and working groups. This position can be based in Redwood City, CA, San Diego, CA, or be field based. Qualifications - M.D., D.O., in a related field. - Completion of fellowship training or equivalent in medical oncology. - Demonstrated expertise in molecular oncology. - Demonstrated ability to lead cross-functional internal and external teams. - Familiarity with laboratory analytical process development and biostatistics. - Authorization to work in the United States without sponsorship. Requirements - 2+ years of experience in healthcare. - Experience in oncology within the pharmaceutical or biotech industry. - Experience working with various drug classes for breast cancer management. - Experience in the development of new oncology therapeutics and molecular diagnostics. - Strong knowledge of FDA and Ex-U.S. regulatory documentation and processes. Benefits - Paid time off (including vacation, holidays, volunteering, and personal time). - Paid leave for parents and caregivers. - Retirement savings plan. - Wellness support. - Health benefits including medical, prescription drug, dental, and vision coverage. Salary Range $300,000-$392,000. The annual base salary shown is a national range for this position on a full-time basis and may differ by hiring location. This position is also bonus eligible.

• Handle clinical, technical, and scientific inquiries from internal and external clients • Provide clinical expertise to laboratory staff and molecular geneticists • Collaborate with molecular geneticists and other departments • Contribute to marketing and business development • Support client and public education through development of educational materials • Assist with training genetic counseling assistants • Maintain professional certification through ongoing education

• Execute, manage and conduct projects associated with the company clinical study plans. • Responsible for site management deliverables on assigned protocols and may act as a lead CRA for the study, providing guidance and support to other CRAs on the team. • Establish and maintain primary Sponsor communication with clinical sites for in-house and outsourced studies. • Conduct oversight visits for outsourced studies to promote study engagement, enrollment and foster sponsor/site relationships. • Serve as a point of contact for investigators and site staff. • Maintain regular contact with study sites to ensure GCP/ICH/Protocol compliance, assessment of accrual rates. • Facilitate communication between the project team and site personnel to ensure that they are appropriately trained and remain current with project requirements. • Support the Clinical Study Manager in developing study-specific training materials. • Conduct thorough site qualifications visits and efficient site initiation visits.