Black Canyon Consulting

Role Description Black Canyon Consulting (BCC) is searching for a Clinical Trials Coordinator to support our work for the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), an institute of the National Institutes of Health. This opportunity is full time and onsite at the NIH-NCBI in Bethesda, MD and/or remote work. The National Center for Biotechnology Information (NCBI) is part of the National Library of Medicine (NLM) at the National Institutes of Health (NIH). NCBI is the world’s premier biomedical center hosting over six million daily users that seek research, clinical, genetic, and other information that directly impacts biomedical research and public health. You will join NCBI’s team of web developers and software engineers to build robust, flexible web applications, APIs, and services. This role calls for an expert web developer with knowledge and experience in modern web development, testing, UI design and usability principles, and the ability to work effectively with user researchers, designers, product managers, scientists, security, and DevOps engineers. Duties & Responsibilities - Assist with the development of protocol, policies, and procedures - Assist with documentation and training of new staff on protocol procedures and required competencies - Participate in protocol development, audits, and required reporting to regulatory bodies and intramural research programs - Ensure compliance with FDA and IRB requirements for IND protocol - Provide agendas for weekly team meetings and record minutes as needed - Contribute to scientific and technical writing including documentation, checklists, and contribution to protocol and manuscripts - Collaborate on related projects, particularly with shared equipment, purchases, and clinical needs - Monitor study progress and develop benchmarks to ensure performance goals are met - Develop and maintain spreadsheets to track study progress - Maintain data and records in compliance with NIH policies and ensure integration with other data systems - Create training materials and track training, including equipment and techniques - Perform lab research, record, and analyze data, including documentation of test results - Ensure adherence to timelines - Document progress using electronic lab notebooks - Prepare summaries and reports - Submit orders for supplies, equipment, and training using NIH systems (e.g., POTS) - Meet weekly with PI, lab members, and clinical staff - Communicate with prospective research participants, perform telephone screens, and work with NIH staff to determine eligibility - Coordinate subject payments, eligibility, calendars, etc. - Complete required clinical trainings and training for study-specific procedures Benefits - Competitive benefits package, including medical, dental, and vision coverage - 401(k) plan with employer contribution - Paid holidays, vacation, and tuition reimbursement - Competitive salary commensurate with experience and location

Role Description Black Canyon Consulting (BCC) seeks a Product Owner to support our work for the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), an institute of the National Institutes of Health. This opportunity is full time and onsite at the NIH-NCBI in Bethesda, MD and/or remote work. NCBI is part of the National Library of Medicine (NLM) at NIH. NCBI is the world’s premier biomedical center hosting over six million daily users that seek research, clinical, genetic, and other information that directly impacts biomedical research and public health – at NCBI you can literally help to accelerate cures for diseases! Job Responsibilities: - Lead team through a complete product lifecycle of discovery to delivery. - Lead data analysis and user research efforts and utilize findings in the development of product requirements and to inform objective decision making. - Develop product vision, goals, and strategic roadmaps and lead the execution. - Prioritize product team actions and provide clear guidance to create incremental value in an Agile environment. - Develop partnerships and collaborations with internal and external stakeholders to improve data usability and impact. Qualifications - Doctorate level degree in bioinformatics, molecular biology, computational biology, data science, computer science, information technology, or a similar field. - Conceptual knowledge of genomics, molecular biology, and computational biology. - Practical knowledge of bioinformatics, bioinformatic tools, and the application of genomic sequencing data to biomedical and other scientific use cases. - Experience leading teams, setting team goals, prioritizing work based on available information and stakeholder needs, and utilizing metrics to measure success. - Experience providing an effective work environment. - The ability to troubleshoot technical and staffing roadblocks and mitigate risks. - Experience in diplomatically resolving conflicting priorities from multiple user groups, technical stakeholders. - Excellent communication skills, including verbal, written, and presentation skills. - Strong interpersonal engagement, networking, and collaboration skills. Requirements - Experience working with SRA or similar sequence databases and applying next generation sequencing data to biological problems. - Experience serving in the capacity of post-doctorate Investigator, Product Owner or Product Manager experience. - Familiarity and commitment to FAIR data practices. - Familiarity or experience working in an Agile environment. - Familiarity with data storage and/or processing in commercial cloud platforms like AWS or GCP. - Working familiarity with one or more scripting languages. - Working familiarity with large SQL databases. - Familiarity with CI/CD pipelines, unit tests, integration, and regression testing. Benefits - Competitive benefits package that includes medical, dental and vision coverage. - 401k plan with employer contribution. - Paid holidays and vacation. - Tuition reimbursement. - Competitive salary commensurate with experience and location.

Role Description Black Canyon Consulting (BCC) is searching for a Lead Ontologist supporting the delivery of knowledge-first systems. We turn fragmented scientific and enterprise data into structured, reusable knowledge assets. These systems are designed to support explainable reasoning, governed analytics, and trustworthy AI. The approach starts with the questions that matter and builds toward the semantics required to address them. This role sits at the boundary between business understanding and technical implementation. You will: - Work with stakeholders to clarify use cases, define competency questions, and translate those into semantic models, schemas, and query patterns. - Design and build models using LinkML and RDF/OWL. - Define query skeletons and ensure that data transformation aligns with the intent of the question. - Communicate results, both internally and with clients, explaining what the system can answer and why. This is a remote-first role, with a preference for U.S.-based candidates working East Coast hours. Travel is limited, generally no more than once per month, and focused on design workshops or key client interactions. Qualifications - Strong experience with semantic standards: RDF, RDFS, OWL. - SPARQL, including query design. - SHACL, with clear understanding of constraints versus semantics. - Experience designing and working with ontologies in real-world systems. - Understanding and practical experience with FAIR (Findable, Accessible, Interoperable, Reusable) Data. - Demonstrated ability to translate business problems into structured representations, including use cases, questions, and models. - Strong communication skills, able to explain technical concepts to non-experts and bridge technology and business needs. - Comfortable working in an iterative, ambiguous environment with evolving requirements. Requirements - Experience with LinkML. - Understanding of Labeled Property Graphs (LPG) and OpenCypher. - Experience with vocabulary standards such as SKOS. - Experience with data catalog and data product standards, including DCAT and DPROD. - Background in life sciences or pharma, including translational medicine, clinical data, or real-world data. - Familiarity with BioLink and other domain models. - Experience with bioinformatics and biomedical ontology resources. - Experience with data profiling, reconciliation, and mapping processes. - Experience with knowledge graph platforms or graph databases. - Experience in client-facing roles such as workshops, design sessions, and presentations. Benefits - Competitive benefits package, including medical, dental, and vision coverage. - 401(k) plan with employer contribution. - Paid holidays, vacation, and tuition reimbursement. - Competitive salary commensurate with experience and location.

Role Description Black Canyon Consulting (BCC) is searching for a Junior/Mid Full Stack Software Engineer with DevOps exposure supporting delivery of knowledge-first systems. You will build systems that turn fragmented scientific and enterprise data into structured, reusable knowledge assets that support explainable reasoning, governed analytics, and trustworthy AI. This is a hands-on engineering role focused on building and operating production-ready applications across frontend, backend, and deployment environments. You will support systems built around a question-driven approach, where APIs, data pipelines, and interfaces align to clearly defined query patterns and system behavior. This is a remote-first role with a preference for U.S.-based candidates working East Coast hours. Work is primarily asynchronous, with periodic coordination across the team. Duties & Responsibilities - Build and maintain web interfaces using React, Next.js, JavaScript, and TypeScript - Implement, debug, and improve backend services in Python, including GraphQL APIs and supporting REST endpoints - Integrate with storage and data sources including local files, SQLite, and S3-compatible systems - Implement application-level security features - Write and maintain automated tests and improve reliability - Support application deployment and operation across environments - Containerize applications using Docker and Docker Compose - Configure environments, logging, TLS, and monitoring - Collaborate across repositories and services Qualifications - 1–4 years of experience or equivalent - Strong Python experience - Experience with React or Next.js - Experience with APIs, including GraphQL or REST - Experience with Docker - Familiarity with Linux environments and debugging - Experience with authentication - Automated testing experience - Willingness to work across the stack Bonus Skills - AWS experience - Knowledge graph familiarity - Experience with graph databases - Exposure to deployment tooling Benefits - Competitive benefits package, including medical, dental, and vision coverage - 401(k) plan with employer contribution - Paid holidays, vacation, and tuition reimbursement - Competitive salary commensurate with experience and location